Altitudinal patterns of bacterial communities across soil layers in the alpine meadows of the Qinghai-Tibet Plateau by Zhiyuan Chen, Yeteng Xu, Xinyue Wang, Tong Ma, Yang Liu, Xiang Qin, Wei Zhang, Tuo Chen, Guangxiu Liu, Binglin Zhang

“…This enhanced understanding is critical for advancing knowledge regarding the functional roles of soil microorganisms in alpine meadow ecosystems and their adaptive responses to climatic fluctuations.…”
Get full text

Effect of cooling rate on metallurgical and mechanical properties in continuous wave laser welding of hot-dip galvanised steel-to-aluminium sheets in a zero part-to-part gap lap jo... by A. Baghbani Barenji, M.B. Russo, S. Jabar, H.R. Kotadia, D. Ceglarek, K.F. Ayarkwa, J.R. Smith, P. Franciosa

“…The work investigates how cooling affects the formation of intermetallic compounds (IMCs) and the behaviour of Zn vapours, both of which are critical factors to the joint strength. IMCs are recognised as the most decisive factor in welding steel to aluminium, while Zn vapours significantly impact welding in a zero part-to-part gap overlap configuration. …”
Get full text

Social media warfare: investigating human-bot engagement in English, Japanese and German during the Russo-Ukrainian war on Twitter and Reddit by Wentao Xu, Kazutoshi Sasahara, Jianxun Chu, Bin Wang, Wenlu Fan, Zhiwen Hu

“…By elucidating these network dynamics, our study contributes to a deeper understanding of how digital platforms can be manipulated in geopolitical conflicts, offering critical perspectives for future research and policy-making.…”
Get full text

QUIET WARRIOR – Rationale and design: An ancillary study to the Women's IschemiA TRial to Reduce Events in Nonobstructive CAD (WARRIOR) by Osama Dasa, Eileen Handberg, Damini Dey, Pinaki Sarder, Margaret C. Lo, Balaji K. Tamarappoo, Steven M. Smith, Leslee J. Shaw, C. Noel Bairey Merz, Carl J. Pepine

“…This research will address critical gaps in managing nonobstructive CAD, promoting more equitable cardiovascular care.…”
Get full text

Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr... by Yue Chen, Biqi Ren, Ningsheng Wang, Shuang Lei, Shuzhi Lin, Lianye Liu, Yufang Xiang, Bianling Feng

“…Introduction The management of diabetes has become a critical public health issue in China. The development of community-based type 2 diabetes management in China has not yet reached an ideal state, and the most suitable management methods for diabetic patients are still being explored. …”
Get full text

Exploring information technology utilization and needs in community pharmacies: a cross-sectional survey in Shanghai, China by Qin Li, Zhao Jin, Yun Liao, Huihua Dai, Jie Meng, Ling Li

“…BackgroundCommunity pharmacists are critical in managing medication therapy and ensuring patient safety. …”
Get full text

Assessment of atmospheric correction methods in MSI imagery for deriving bathymetry and substrates of shallow-water coral reefs by Wei Huang, Wei Huang, Wei Huang, Wei Huang, Jun Zhao, Mingjie Li, Mingjie Li, Mingjie Li, Quansheng Lou, Quansheng Lou, Nanyang Yan, Nanyang Yan, Nanyang Yan, Shaojie Sun

“…This study underscores the critical role of accurate AC in retrieving bathymetry and coral reef substrate information from optically shallow waters using medium- to high-resolution MSI imagery. …”
Get full text

Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

“…Abstract Background Acute Osteofascial Compartment Syndrome (AOCS) stands as a critical surgical emergency, often secondary to various diseases. …”
Get full text

Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection by Ekong E. Udoh, Ubong A. Udoh, Abiodun Egwuenu, Ekpereonne B. Esu, Aruk Eteng, Faithman E. Ovat, Uduak Okomo, Olabisi Oduwole, Joseph Okebe, Martin Meremikwu

“…Contributions: Primary studies addressing this critical question are required to guide public health recommendations and policies.…”
Get full text

Mathematical modelling and optimization of cutting conditions in turning operation on MDN 350 steel with carbide inserts by Syed Adil, A. Krishnaiah, D. Srinivas Rao

“…Hard metals are victorious in offering greater functional life in various critical applications because of their excellent material characteristics. …”
Get full text

Exploring the Antioxidant and Neuroprotective Potential of Muscari armeniacum: Phenolic Profiling and Enzyme Inhibition by Fevzi Topal, Firat Yılmaz, Meryem Topal, Ahmed Menevşeoğlu

“…Additionally, the total phenolic and flavonoid contents of the extracts were determined, as these compounds are critical indicators of antioxidant potential. The antioxidant activity of Muscari armeniacum was compared with five standard antioxidants commonly used for benchmarking: BHA, α-tocopherol, BHT, trolox, and ascorbic acid. …”
Get full text

How can urban expansion and ecological preservation be balanced? A simulation of the spatial dynamics of production-living-ecological spaces in the Huaihe River Eco-Economic Belt by Tonghui Yu, Shanshan Jia, Yu Zhang, Xufeng Cui

“…Overall, considering the vulnerability of production space to further encroachment, future strategies for the Huaihe River Eco-Economic Belt should prioritize protecting high-quality farmland and critical ecological zones, while regulating urban expansion and strengthening land-use planning to ensure PLES sustainability. …”
Get full text

Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations by Lucas Tricoli, Sunetra Sase, Julia L. Hacker, Vi Pham, Maxwell Chappell, Laura Breda, Stephanie N. Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Matthew Hogenauer, Aoife Roche, John Everett, Frederic Bushman, Peter Kurre, Rebecca Ahrens-Nicklas, Laura A. Adang, Adeline L. Vanderver, Stefano Rivella

“…Our top-performing vector (EA1) showed at least 4× more ARSA activity than the currently US and European Union (EU)-approved vector and a superior ability to secrete vesicle-associated ARSA, a critical modality to transfer functional enzymes from microglia to oligodendrocytes. …”
Get full text

Verbal fluency and semantic association deficits in children with in birth nonprogressive neuromuscular diseases by Maria Koriakina, Maria Koriakina, Olga E. Agranovich, Ioannis Ntoumanis, Maxim Ulanov, Isak B. Blank, Anna Shestakova, Evgeny Blagovechtchenski

“…This relevance is particularly noted in children with severe motor disorders (MD) from birth, highlighting a need to explore how these disorders may impede cognitive functions.MethodsIn this study, we assessed verbal fluency, a critical component of speech function, in 68 children aged 7 to 15. …”
Get full text

Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study by Gaoyang Li, Shrikant S. Kolan, Franco Grimolizzi, Joseph Sexton, Giulia Malachin, Guro Goll, Tore K. Kvien, Tore K. Kvien, Nina Paulshus Sundlisæter, Manuela Zucknick, Siri Lillegraven, Espen A. Haavardsholm, Espen A. Haavardsholm, Bjørn Steen Skålhegg

“…IntroductionAchieving remission is a critical therapeutic goal in the management of rheumatoid arthritis (RA). …”
Get full text

Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Radiation oncologists and immunologists convened a virtual consensus discussion to identify current deficiencies, challenges, pitfalls and critical gaps when combining radiotherapy with immunotherapy and making recommendations to the field and advise National Cancer Institute on new directions and initiatives that will help further development of these two fields.This commentary aims to raise the awareness of this complexity so that the need to study radiation dose, fractionation, type and volume is understood and valued by the immuno-oncology research community. …”
Get full text

Best practice mechanisms for biodiversity conservation law and policy by Callum Brockett, Katie Woolaston, Felicity Deane, Fran Humphries, Ethan Kumar, Amanda Kennedy, Justine Bell-James

“…Laws for the conservation of biodiversity form a critical component for minimising the drivers of extinction, with species extinction being an extreme outcome of biodiversity loss. …”
Get full text

HIV status and contraceptive use in Zimbabwe among sexually active adolescent girls and women: Secondary analysis of Zimbabwe Demographic Health survey data by G Musuka, G Murewanhema, Z Mukandavire, I Chingombe, D Cuadros, F Mutenherwa, T Dzinamarira, R Eghtessadi, N Malunguza, M Mapingure

“…Understanding the pattern of contraceptive use among women living with HIV is critical for formulating relevant public health interventions to improve the uptake and use of reliable methods in this population. …”
Get full text

An Efficient and Hybrid Deep Learning-Driven Model to Enhance Security and Performance of Healthcare Internet of Things by Muhammad Babar, Muhammad Usman Tariq, Basit Qureshi, Zabeeh Ullah, Fahim Arif, Zahid Khan

“…However, H-IoT devices present security and Quality of Service (QoS) concerns because of their critical nature, complexity, and dynamic features, which make them incompatible with conventional network topologies. …”
Get full text

Indoor Air Exposure to Multiple Agricultural Pesticides Potentially Posing the Highest Risk to Young Children by Sithembiso Sifiso Msibi, Chung-Yu Chen, Cheng-Ping Chang, Chiou-Jong Chen, Su-Yin Chiang, Kuen-Yuh Wu

“…Abstract Pesticides are extensively used to improve crop yield and quality in many African countries where agricultural production is a critical economic activity, including Eswatini (formerly Swaziland) in southern Africa. …”
Get full text