Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin by Anna Maria Cybulska, Daria Schneider-Matyka, Ireneusz Walaszek, Mariusz Panczyk, Dorota Ćwiek, Anna Lubkowska, Elżbieta Grochans, Kamila Rachubińska, Katarzyna Malewicz, Mariusz Chabowski, Mariusz Chabowski

“…The selection of visfatin, adropin, and adiponectin as biomarkers is based on their significant roles in metabolic regulation and inflammation, which are critical factors in cardiometabolic risk. Visfatin is known for its pro-inflammatory properties and its ability to modulate insulin resistance. …”
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Current status and development trends of deep coalbed methane research in China by Wei JU, Shu TAO, Zhaobiao YANG, Jiayao CHENG, Haiyan SHANG, Weike NING, Chunlong WU

“…Conducting geology and engineering integrated research for deep CBM exploration and development, based on the quantitative characterization of geological and engineering parameters and using three-dimensional geological and geomechanical modeling, is a critical pathway to ensuring profitable development. …”
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Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer by Maria Elena Lacruz, Saskia Thies, Andrea Schmidt-Pokrzywniak, Ian Wittenberg, Tobias Engler, Fabian Reinwald, Monika Klinkhammer-Schalke, Sylke Ruth Zeissig, Bianca Franke, Kerstin Weitmann, Atanas Ignatov

“…While metastatic behaviour, treatment and long-term response in HER2-low were comparable to HER2-zero, the hormone receptor status seems to play a critical role in these outcomes.…”
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Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration by Riginos, Cynthia, Popovic, Iva, Meziere, Zoe, Garcia, Vhon, Byrne, Ilha, Howitt, Samantha M., Ishida, Hisatake, Bairos-Novak, Kevin, Humanes, Adriana, Scharfenstein, Hugo, Richards, Thomas, Briggs, Ethan, Clark, Vanessa, Lei, Chuan, Khan, Mariam, Prata, Katharine E.

“…Incorporating the expectation that coral cryptic taxa with incomplete species boundaries will frequently be encountered is critical to the long-term success of coral conservation and restoration programs. …”
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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…Background Nigeria faces a critical shortage of healthcare professionals yet experiences a significant annual exodus of doctors and dentists. …”
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Effect of dietary starch inclusion, feeding level and their combination on nutrient digestibility, bile acid balance, faecal waste production and characteristics of yellowtail king... by Yaqing Zhang, Roel M. Maas, Peter Horstmann Zuther, Jeroen Kals, Satya Prakash, Thomas W.O. Staessen, Fotini Kokou, Johan W. Schrama

“…High dietary starch levels resulted in increased faecal waste production, and higher amounts of non-removed faeces by settling due to reduced faecal removal efficiency. The critical dietary starch content was estimated to be 6 %. …”
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Recommendations of the Russian Gastroenterological Association on Clinical Use of High-Resolution Manometry in Diagnosis of Esophageal Disorders by V. T. Ivashkin, I. V. Mayev, A. S. Trukhmanov, O. A. Storonova, S. A. Abdulkhakov, D. N. Andreev, D. S. Bordin, E. R. Valitova, I. L. Klyaritskaya, V. V. Krivoy, Yu. A. Kucheryavyi, T. L. Lapina, S. V. Morozov, O. A. Sablin, E. V. Semenikhina, Yu. P. Uspenskiy, A. A. Sheptulin

“…It enables a medical professional to obtain evidence that may critically affect the choice of optimal patient care strategy and effective treatment. …”
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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Hence, it is necessary to investigate the potential of medication history as a predictor of survival outcomes among AKI patients in the intensive care unit (ICU). Methods Critically ill AKI patients were sourced from the MIMIC-IV database. …”
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Efficient adsorption of ofloxacin in a novel nanocomposite formed by nano-hexagonal boron nitride fused with zeolite imidazolite skeleton-8: Experimental and molecular dynamics sim... by Zefang Huang, Yuankai Hong, Yiqun Cui, Huiying Guo, Yan Long, Jinshao Ye

“…With the widespread application of antibiotics in the medical field, associated wastewater pollution has become a critical environmental issue, creating potential risks to ecosystems and public health. …”
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Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes by Haiyong Zeng, Fei Yu, Haofei Hu, Yong Han, Ruixue Ye, Changchun Cao

“…Furthermore, a nonlinear relationship was identified between HSI levels and the reversion to NGR, with a critical threshold at an HSI value of 43.08. Below this threshold, a strong negative association was observed, markedly enhancing the probability of returning to normoglycemic status (HR = 0.91, 95% CI: 0.88–0.94, P < 0.0001). …”
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Development of a novel strategy for the quantification of ultra-trace impurity elements in high-purity magnesium using inductively coupled plasma tandem mass spectrometry by Liang Fu, Guangsheng Huang, Yaobo Hu, Xianhua Chen, Jingfeng Wang, Fusheng Pan

“…Impurities in high-purity magnesium affect material properties, which has become the most critical factor restricting its application. However, accurate analysis of multiple ultra-trace impurity elements in high-purity magnesium is extremely challenging. …”
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Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae by Lisa Zierke, Rodi Mourad, Thomas P. Kohler, Mathias Müsken, Sven Hammerschmidt

“…IntroductionThe capsular polysaccharide (CPS) of pathogenic bacteria is a critical virulence factor, often evading phagocytosis by host immune cells, while also interfering with the contact of the pathogen with host cells and contributing to biofilm formation. …”
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A medical insurance fund operation performance evaluation system under the DRG payment mode reform by Zijian Wang, Zijian Wang, Zijian Wang, Weifu Chang, Weifu Chang, Aijing Luo, Aijing Luo, Aijing Luo

“…BackgroundAn evaluation system for comprehensively measuring medical insurance fund operational performance under China’s Diagnosis Related Groups (DRG) payment reform holds critical theoretical and practical significance, especially for enhancing the efficiency of medical insurance fund utilization and the quality of healthcare services. …”
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Assessing the Direct Impact of Typhoons on Vegetation Canopy Structure and Photosynthesis by Yaoyao Zheng, Simin Zhan, Zaichun Zhu, Sen Cao, Jiana Chen, Pengjun Zhao, Weimin Wang, Ranga B. Myneni

“…These ecosystems provide critical ecological, social, and economic functions, making accurate assessment of typhoon impacts essential for effective management and disaster risk reduction. …”
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Sociodemographic, lifestyle, and psychological factors as controllable predictors of academic self-efficacy after reforming a medical education system; the Egyptian Nationwide expe... by Ahmed Amir Samir, Ahmed Hussein Elamir, Mohamed Basyouni Helal, Yomna Goudy, Khaled Elbarbary, Mohamed El-Mezayen, Wesam Abo-Elenien, Ebtehal Hashem Abdelazim, Manar Alaa Mabrouk, the ASE-Egypt Group, Kerollos Abdelsayed

“…Abstract Background Academic self-efficacy (ASE), influenced by various sociodemographic, lifestyle, and psychological factors, is a critical determinant of academic performance in medical students. …”
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Geospatial Modelling for Estimation of PM2.5 Concentrations in Two Megacities in Peninsular India by V. P. Lavanyaa, S. Varshini, Souvik Sankar Mitra, Kiran M. Hungund, Rudrodip Majumdar, R. Srikanth

“…These spatiotemporal maps of PM2.5 concentration are critical to overcoming the misclassification of exposure and will form a crucial input to much-needed PM exposure-response studies in these two megacities. …”
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TEACHERS’ AND STUDENTS’ ATTITUDES TOWARDS THE USE OF ARTIFICIAL INTELLIGENCE: ALL-UKRAINIAN RESEARCH by Stanislav Dovgyi, Svitlana Babiichuk, Lidiia Davybida, Mariia Biletska

“…Understanding the essential role of teachers and students as active participants in this transformation, as well as the factors influencing their perceptions and attitudes toward AI, is critical. In Ukraine, the emergence and rapid spread of accessible AI tools occurred during a time of full-scale military conflict, bringing about drastic disruptions to traditional educational processes. …”
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Digital Literacy on SME Business Performance and The Mediating Role of Entrepreneurial Skills by Intan Novela Q.A, Hunik Sri Runing Sawitri, Asri Laksmi Riani, Suryandari Istiqomah, Anastasia Riani Suprapti, Mugi Harsono

“…By linking digital literacy to strategic business study highlights its critical importance in navigating the modern digital economy. …”
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Exploring patient preferences for intraocular lenses selection in age-related cataract: a discrete choice experiment study by Qiaolin Zhu, Qiaolin Zhu, Qiaolin Zhu, Qianqian Sun, Qianqian Sun, Qianqian Sun, Yujia Huo, Yujia Huo, Yujia Huo, Xiaoling Yang, Xiaoling Yang, Xiaoling Yang, Hehe Huang, Hehe Huang, Hehe Huang, Shanshan Qian, Shanshan Qian, Shanshan Qian, Wenjing Lin, Wentao Yan, Wentao Yan, Wentao Yan

“…Multinomial logistic regression analysis further showed that male patients were more likely to choose toric IOLs, while individuals with higher education levels were significantly less likely to prefer multifocal IOLs.ConclusionThis study highlights significant heterogeneity in cataract patient preferences for IOLs attributes. Cost was the most critical factor, followed by presbyopia and aberration correction. …”
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The hypoxia adaptation strategy of the big-belly seahorses (Hippocampus abdominalis) with tuft gills by Long-Wu Jia, Le-Le Zhang, Hong-Wei Yang, Chun-Yu Hou, Lin Shi, Yu-Ping Hou, Guo-Dong Zheng, Xiao-Lei Su, Kai Wang

“…Hypoxia tolerance is a critical trait in fish breeding, however, the mechanisms underlying hypoxia regulation in the tuft gills of seahorses remain unclear. …”
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