Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…The hydrogel group exhibited a significant promotion in collagen content and reduction in HIF-1α, which effectively hastened tract maturation.Conclusion: Therefore, our study provides new and critical insights into a strategy to design bioactive hydrogels with multiple functions, which can open up a new avenue for accelerated wound healing after gastrostomy. …”
Get full text

Comparing physician associates and foundation year two doctors-in-training undertaking emergency medicine consultations in England: a mixed-methods study of processes and outcomes by Simon de Lusignan, Mary Halter, Carly Wheeler, Laura Nice, Sally Brearley, James Ennis, Jonathan Gabe, Heather Gage, Phil Begg, Chao Wang, Jim Parle, Vari Drennan

Get full text

Sputum Smear Positive Pulmonary Tuberculosis Diagnostic Dropout Rate in Public Health Facilities, Addis Ababa, Ethiopia by Daniel Melese Desalegn, Kumera Terfa Kitila, Boja Dufera Taddese, Tinsae Kidanemariam Hailu, Tariku Takle Dinku, Kassahun Demisse Asferie, Hanna Mekonnen Balcha, Chalachew Sisay Gebeyehu, Girmay Medhin

“…This implies such dropout patients without completing diagnosis are critical as infected individuals remain untreated in the community, providing more opportunities for transmission of the disease and adversely affecting the epidemic. …”
Get full text

CXCR4 promotes tumor stemness maintenance and CDK4/6 inhibitors resistance in ER-positive breast cancer by Qiangfeng Shi, Wang Yang, Yiye Ouyang, Yujie Liu, Zijie Cai

“…Results In our study, we focused on cancer stem cells, a critical contributor to cancer metastasis and therapy resistance, and detected an upregulation of stemness in our established palbociclib-resistant ER-positive breast cancer cells. …”
Get full text

Optimization of SiC reinforced Al7039/Cu composites for enhanced thermal conductivity and hardness via response surface methodology by Fetene Teshome Teferi, Kishor Purushottam Kolhe, Assefa Asmare Tsegaw, Samuel Olawale Fatoba

“…The optimized Al7039/Cu/SiC composites exhibit significant enhancements over the base alloy, offering excellent properties suitable for demanding applications such as heat sinks, heat exchangers, mold tooling, and critical components in the automotive and aerospace sectors. …”
Get full text

Cost Savings in Chronic Pain Patients Initiating Peripheral Nerve Stimulation (PNS) with a 60-Day PNS Treatment by David M. Dickerson, Hemant Kalia, Kevin E. Vorenkamp, Konstantin V. Slavin, Jonathan M. Hagedorn, Candace Gunnarsson, Eric L. Keuffel, Andrew J. Epstein, Mark Stultz, Nathan D. Crosby

Get full text

Co-producing a safe mobility and falls informatics platform to drive meaningful quality improvement in the hospital setting: a mixed-methods protocol for the insightFall study by Ben Glampson, Clare Leon-Villapalos, Erik Mayer, Rachael Lear, Phoebe Averill, Catalina Carenzo, Rachel Tao, Robert Latchford

Get full text

An ensemble machine learning-based performance evaluation identifies top In-Silico pathogenicity prediction methods that best classify driver mutations in cancer by Subrata Das, Vatsal Patel, Shouvik Chakravarty, Arnab Ghosh, Anirban Mukhopadhyay, Nidhan K. Biswas

“…Abstract Background and objective Accurate identification and prioritization of driver-mutations in cancer is critical for effective patient management. Despite the presence of numerous bioinformatic algorithms for estimating mutation pathogenicity, there is significant variation in their assessments. …”
Get full text

Preparation of Mo2C/MWCNT catalysts and its performance in electrocatalytic oxidation of methanol by Leixin MAO, Lin FU, Lei LIU, Zhihua GAO, Wei HUANG, Zhijun ZUO

“…The anode catalyst of direct methanol fuel cell is the most critical component, and its catalytic performance directly affects the performance of the cell. …”
Get full text

Developing a Machine Learning–Based Automated Patient Engagement Estimator for Telehealth: Algorithm Development and Validation Study by Pooja Guhan, Naman Awasthi, Kathryn McDonald, Kristin Bussell, Gloria Reeves, Dinesh Manocha, Aniket Bera

“… BackgroundPatient engagement is a critical but challenging public health priority in behavioral health care. …”
Get full text

Multivariate Statistical Analysis Reveals the Heterogeneity of Lacustrine Tight Oil Accumulation in the Middle Permian Jimusar Sag, Junggar Basin, NW China by Yuce Wang, Jian Cao, Keyu Tao, Xiuwei Gao, Erting Li, Chunhua Shi

“…This heterogeneity, however, is hard to investigate by conventional geological and (organic) geochemical tools and thus is critical and challenging to study. Here, we attempted multivariate statistical analysis to reveal the heterogeneity based on a case study in the lacustrine tight oil accumulation in the middle Permian Lucaogou Formation of the Jimusar sag, Junggar Basin, NW China. …”
Get full text

Engagement and Follower Growth: Social Media Strategies of Swiss Athletes at the Paris Olympics by Larssyn Staley, Florian Droux

“…Understanding the factors driving engagement and follower growth on social media during high-visibility events is critical for athletes to leverage their athletic performance for brand growth and endorsement opportunities (Bredikhina et al., 2023; Su et al., 2020). …”
Get full text

A STUDY OF THE INFLUENCE OF EXTRACELLULAR VESICLES ON THE MORPHOFUNCTIONAL STATE OF THE ENDOMETRIUM IN VITRO by Оксана Александровна Мелкозерова, Ирина Викторовна Крутинь, Александра Юрьевна Храмцова, Мария Валерьевна Улитко, Алсу Фармутовна Мустафина

“…When adding vesicles, no critical changes in the structure of the cell cytoplasm were detected, it remains homogeneous. …”
Get full text

Sibling Species Composition and Susceptibility Status of Anopheles gambiae s.l. to Insecticides Used for Indoor Residual Spraying in Eastern Uganda by Julius Iga, Stephen Ochaya, Richard Echodu, Elizabeth A. Opiyo, Alex K. Musiime, Angella Nakamaanya, Geoffrey M. Malinga

“…Malaria remains one of the most critical disease causing morbidity and mortality in Uganda. …”
Get full text

Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study by Wang Q, Yin Y, Liu W, Li L, Wang Z, Tian Y, Fan J

“…Qing Wang,1,* Yishan Yin,2,* Wei Liu,3,* Lingyu Li,1 Zhen Wang,1 Yue Tian,1 Jing Fan1 1Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 2Department of Orthopedics, The Armed Police Forces Hospital of Shandong, Jinan, Shandong, 250000, People’s Republic of China; 3Department of Emergency Critical Care Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Fan, Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email sddzfanjing@163.comBackground: This study investigates the correlation between the weight-adjusted waist index (WWI) and cognitive performance in the senior American population, focusing on those without diabetes from 2011 to 2014.Methods: We analyzed data from the 2011– 2012 and 2013– 2014 National Health and Nutrition Examination Surveys (NHANES), focusing on non-diabetic participants aged 60 and older who completed cognitive tests: Establish a Registry for Alzheimer’s disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). …”
Get full text

Migration, race, and gender: the policing of subversive solidarity actors in Morocco by Sébastien Bachelet, Maria Hagan

“…This article investigates the policing of “subversive solidarity actors”: human rights defenders and activists who publicly or covertly engage in a critical stance on migration control policies and practices in Morocco. …”
Get full text

Efficient virtual machine placement in cloud computing environment using BSO-ANN based hybrid technique by Pradeep Singh Rawat, Sachin Gaur, Varun Barthwal, Punti Gupta, Debjani Ghosh, Deepak Gupta, Joel JP C. Rodrigues

“…Efficient virtual machine placement is a critical aspect of optimizing resource utilization, reducing operational costs, energy consumption, service level agreement and minimum virtual machine migrations, execution time, and ensuring the overall performance of cloud services. …”
Get full text

Soil-transmitted helminthiasis among adolescents in Anaocha Local Government Area, Anambra State, Nigeria: Insights and recommendations for effective control. by Ogechukwu B Aribodor, Eunice C Jacob, Nwadiuto O Azugo, Uche C Ngenegbo, Ifeanyi Obika, Emmanuel M Obikwelu, Obiageli J Nebe

“…Our study aimed to address this critical knowledge gap by assessing soil-transmitted helminthiasis (STH) prevalence and contextual factors hindering effective control among adolescents in Anambra State, Nigeria. …”
Get full text

Genome-wide identification of short-chain dehydrogenases/reductases genes and functional characterization of ApSDR53C2 in melanin biosynthesis in Arthrinium phaeospermum by Jiao Liao, Yisi Wang, Han Liu, Sijia Liu, Peng Yan, Hang Chen, Shujiang Li, Shujiang Li

“…The results of phenotypic and stress conditions analysis indicate that ApSDRs are critical for the growth, development, stress response, and fungicide resistance of A. phaeospermum. …”
Get full text

Appropriate nitrogen application under ridge-furrow plastic film mulching planting optimizes spring maize growth characteristics by improving soil quality in the Loess Plateau of C... by Fan Zhang, Mengru Chen, Yingying Xing, Xiukang Wang

“…Soil properties exhibited highly correlated with crop growth characteristics, among which AP, SPA, SCA, and SUA were identified as critical soil factors for monitoring crop growth, yield, and WP. …”
Get full text