Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway by Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao

“…Our study indicates a critical role for cellular cholesterol deficiency in AD-related synaptopathy, thus highlighting the potential for targeting cellular cholesterol metabolism in therapeutic strategies.…”
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Entrepreneurship education for women through project-based flipped learning: The impact of innovativeness and risk-taking on course satisfaction by Seung-chul Yoo, Tu Anh Truong, Kwanghee Jung

“…Further, we question the established importance of risk-taking, necessitating a critical reassessment in this domain. These pivotal theoretical contributions challenge prevailing assumptions, enrich scholarly discourse, and open new avenues for research. …”
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Evolution and effectiveness of bilateral and multilateral development assistance for health: a mixed-methods review of trends and strategic shifts (1990–2022) by Yan Luo, Ying Chen, Beibei Yuan, Ming Xu, Shuduo Zhou, Zhijie Zheng, Siwei Xie, Sijin Du, Yuxin Huang

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Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017–2021: a retrospective study by Andre A. N. Bovell, Thendo Ramaliba, Sekeena O. Goodwin, Joycelyn C. Phillip, Jabulani Ncayiyana, Themba G. Ginindza

“…In Antigua and Barbuda, understanding the burden of common cancers such as female breast, cervical, colorectal and prostate cancers is critical. This study aimed to assess the incidence, trends, and patterns of these four cancers from 2017 to 2021. …”
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Managing cardiovascular events, hyperglycemia, and obesity in type 2 diabetes through microRNA regulation linked to glucagon-like peptide-1 receptor agonists by Xiaolei Miao, Maryam Davoudi, Zahra Alitotonchi, Ensieh Sadat Ahmadi, Fatemeh Amraee, Ashraf Alemi, Reza Afrisham

“…Liraglutide modulates critical regulators of endothelial cell function and atherosclerosis, including miR-93-5p, miR-26a-5p, and miR-181a-5p. …”
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Efferocytosis and inflammation: a bibliometric and systematic analysis by Xin Cao, Xin Cao, Fen Li, Fen Li, Xi Xie, Xi Xie, Guanghui Ling, Guanghui Ling, Xiaoyu Tang, Xiaoyu Tang, Wenfang He, Jing Tian, Jing Tian, Yan Ge, Yan Ge

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Synergistic effect of mulch and nitrogen management on growth and essential oil yield of Salvia sclarea L. by Diksha Dhiman, Sakshi Vishvamitera, Sidharth Baghla, Sanatsujat Singh, Dinesh Kumar, Ashok Kumar, Ramesh Chauhan

“…Abstract Balanced plant nutrition and optimal micro-climate are critical for achieving higher production sustainably. …”
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Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study by Rahaf Hamdan BinHamdan, Salwa Abdulrahman Alsadhan, Arwa Zohair Gazzaz, AlBandary Hassan AlJameel

“…In Saudi Arabia, where platforms like WhatsApp, Snapchat, and Instagram are widely used, the quality and credibility of oral health information shared digitally remain critical issues. Misconceptions about oral health can negatively influence individuals’ behaviors and oral health outcomes. …”
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Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…The machine learning model exhibited commendable classification capability and outperformed the diagnostic performance of less-experienced radiologists. Critical relevance statement The ultrasound radiomics-based machine learning model holds the potential to elevate the professional ability of less-experienced radiologists and can be used to assist in the clinical screening of ovarian cancer. …”
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MANAGING MAXILLARY BONE LOSS USING GROWTH FACTORS IN PRE-IMPLANT THERAPY by Cardas Adelina, Stratan Ion, Moraru Daliana, Tibeica Andreea, Agop-Forna Doriana, Norina Forna

“…Bone augmentation and sinus lift procedures are critical components of implant dentistry, particularly for patients experiencing insufficient bone volume in the maxilla due to tooth loss and maxillary sinus pneumatization. …”
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The association between bone density of lumbar spines and different daily protein intake in different renal function by Chia-Lin Lee, Kun-Hui Chen, Wei‑Ju Liu, Ching-Hsien Chen, Shang-Feng Tsai

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Multi-modal characterisation of early-stage, subclinical cardiac deterioration in patients with type 2 diabetes by Ambre Bertrand, Andrew Lewis, Julia Camps, Vicente Grau, Blanca Rodriguez

“…Detection of early signs of cardiac deterioration in T2DM patients is critical for prevention. Our goal is to quantify T2DM-driven abnormalities in ECG and cardiac imaging biomarkers leading to cardiovascular disease. …”
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The influence of walking accessibility on station-to-station passenger flow and its interaction with metropolitan race/class segregation: A case study of MARTA’s heavy-rail network... by Luis Enrique Ramos-Santiago, Luke Derochers

“…In several ways this is a more valid unit of analysis for rail ridership studies as it captures critical factors between and at both ends of the trip that are experienced by the passenger. …”
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A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance by Annie Sparrow, Meghan Smith-Torino, Samuel M. Shamamba, Bisimwa Chirakarhula, Maranatha A. Lwaboshi, Christine Stabell Benn, Konstantin Chumakov

“…The World Health Organization (WHO), part of the One Health alliance, focuses mainly on antibiotics and vaccines to reduce deaths due to superbugs and largely ignores the critical role of chlorine to control water-borne diseases (including polio) and other infections. …”
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A MALDI-TOF MS-based multiple detection panel of drug resistance-associated multiple single-nucleotide polymorphisms in Candida tropicalis by Feifei Wan, Min Zhang, Jian Guo, Huiping Lin, Xiaoguang Zhou, Lixin Wang, Wenjuan Wu

“…The SNP panel enables identification of specific mutations at critical sites of drug-resistant strains to facilitate the rapid selection of appropriate antifungal agents and efficient monitoring of the regional epidemiological trends of resistance of C. tropicalis.IMPORTANCEC. tropicalis infections pose a growing global public health challenge, with mortality rates approaching 40%. …”
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Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus by Qiong Huang, Wenbin Nan, Baimei He, Zhenhua Xing, Zhenyu Peng

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Short humeral stem in total shoulder arthroplasty does not jeopardize primary implant stability by Giulia Galteri, MSc, Sara Montanari, PhD, Giacomo Dozza, BSc, Marco Palanca, PhD, Luca Cristofolini, PhD

“…A torsional load was applied to generate the most critical loading condition. The specimens were loaded with 100 cycles between 2 Nm and 10 Nm, at 1 Hz. …”
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Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review by Amelia Wild, Clare Shortall, Omar Dewachi, Carine Naim, Alex Green, Sarah Hussain, Aula Abbara

“…A total of 1,942 distinct microbiological isolates were reported, representing all four critical and high priority GLASS pathogen categories. …”
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Proteomic analysis of spinal dorsal horn in prior exercise protection against neuropathic pain by Binglin Chen, Jiabao Guo, Chan Gong, Chenchen Zhu, Yang Wu, Shengbo Wang, Yili Zheng, Haixia Lu

“…GO and KEGG enrichment analysis revealed that oxygen transport capacity and the complement and coagulation cascades may be the critical mechanism by which prior exercise protects against NP. …”
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Delta Neutrophil Index in Coronary Artery Bypass Surgery: An Innovation in Postoperative Mortality Assessment by Bilgiç A, Toprak B, Kaya H

“…A 1-unit increase in postoperative DNI measurement was associated with a 10.21-fold (95% Confidence Interval: 5.08– 20.05) increase in the risk of death.Conclusion: Elevated DNI values are strong independent predictors of postoperative mortality, underscoring its critical role in perioperative risk assessment for CABG patients. …”
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