Comprehensive computational analysis of differentially expressed miRNAs and their influence on transcriptomic signatures in prostate cancer by Fahad M. Aldakheel, Hadeel Alnajran, Ayesha Mateen, Shatha A. Alduraywish, Mohammed S. Alqahtani, Rabbani Syed

“…This analysis uncovered their substantial impact on critical biological processes and molecular functions, such as cyclin-dependent protein kinase activity, mitotic DNA damage checkpoint signalling, stress-activated MAPK cascade, regulation of extrinsic apoptotic signalling pathway, and positive regulation of cell adhesion. …”
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The development and pilot testing of a behavioral activation-based treatment for depressed mood and multiple health behavior change in patients with recent acute coronary syndrome. by Emily C Gathright, Katherine Diaz Vickery, Woubeshet Ayenew, Matthew C Whited, Melissa Adkins-Hempel, Michelle Chrastek, Jill K Carter, Rochelle K Rosen, Wen-Chih Wu, Andrew M Busch

“…Behavioral Activation (BA) offers an intervention framework for an integrated treatment targeting both depression and critical health behaviors post-ACS. Behavioral Activation for Health and Depression (BA-HD) was developed and pilot tested in a multiphase iterative process.…”
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Analytical performance of OncoPrism-HNSCC, an RNA-based assay to inform immune checkpoint inhibitor treatment decisions for recurrent/metastatic head and neck squamous cell carcino... by Jeffrey Hiken, Jon Earls, Kevin C. Flanagan, Rachel L. Wellinghoff, Michelle Ponder, David N. Messina, Jarret I. Glasscock, Eric J. Duncavage

“…Clinical tests that guide the use of ICIs are therefore critically needed. OncoPrism-HNSCC was developed to address this need. …”
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Prognostic risk factors of pneumonia associated with COVID-19 in patients with lymphoma by Dan Liu, Xia Yin, Hui Wang, Lijie Xing, Ping Li, Haichen Wei, Ji Ma, Qiang He, Linna Xie, Ke Lu, Zengjun Li

“…Lymphoma is the most prevalent hematologic malignancy. It is critical to identify patients at high risk of contracting COVID-19-associated pneumonia.MethodsFrom January 11–31, 2023, we distributed questionnaires to patients diagnosed with lymphoma according to 2016 World Health Organization diagnostic and classification criteria. …”
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Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level by Giusy Rita Maria La Rosa, Alejandro Ismael Lorenzo-Pouso, Vito Carlo Alberto Caponio, Mariangela Valentina Puci, Mariangela Valentina Puci

“…The bias risk was assessed using the Joanna Briggs Institute critical appraisal tools and a biases' report selected from the Oxford Centre for Evidence Based Medicine Catalogue of Bias. …”
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Validation of the REDS score in hospitalised patients who deteriorated and were admitted to the intensive care unit—a retrospective cohort study by Narani Sivayoham, Oliver Mason, Harriet O’Mara, Natasha Trenchard Turner, Katie Sysum, Georgina Wicks

“…The National Early Warning Score2 (NEWS2), REDS, Sequential Organ Failure Assessment (SOFA) and change-in-SOFA (ΔSOFA) scores were calculated at the time of referral to the Critical Care Outreach Team (CCOT). The primary outcome measure was in-hospital all-cause mortality. …”
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The Association Between COVID-19 Vaccination Uptake and Information-Seeking Behaviors Using the Internet: Nationwide Cross-Sectional Study by Kazuya Taira, Misa Shiomi, Takayo Nakabe, Yuichi Imanaka

“…The study highlights the critical role of credible online sources in public health communication and the challenge of combating misinformation on less regulated platforms. …”
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Spectrum, Pattern, and Clinical Outcomes of Adult Emergency Department Admissions in Selected Hospitals of Western Ethiopia: A Hospital-Based Prospective Study by Ashenafi Habte Woyessa, Birhanu Yadecha Dibaba, Getahun Fetensa Hirko, Thanasekaran Palanichamy

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Assessment in education: Current trends, problems and contradictions (review of scientific publications) by I. B. Shmigirilova, A. S. Rvanova, O. V. Grigorenko

“…In addition, an obstacle to ensuring effective assessment of students’ educational achievements is the insufficient level of competence of teachers as assessors, the unpreparedness of students themselves to take responsibility for the results of their learning.Scientific novelty. From a critical standpoint, the ideas are presented and the results of discussions on the problems of assessing the educational results of students in scientific sources are summarised. …”
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Development and Evaluation of an ICU Nurse Training Program on Oral Mucosal Pressure Injury Prevention and Management Using the ADDIE Model by Jia T, Lan Y, Pang J, Ma M, Ding Z, Wang Y, Jiang E

“…The ICU nurses’ knowledge, attitude, and practice in preventing medical device-related pressure injury in critically ill patients and the incidence of oral MMPI were compared before and after the training program.Results: A particular training course program for the ICU nurses to care for oral MMPI was constructed in this study. …”
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Mitigation of environmental impacts in ornamental rock and limestone aggregate quarries in arid and semi-arid areas by M.A. Peñaranda Barba, V. Alarcón Martínez, I. Gómez Lucas, J. Navarro Pedreño

“…FINDINGS: According to the environmental impact assessment studies analysed, the importance of the most significant environmental impacts has been calculated, indicating whether the impacts are critical, severe, moderate or compatible, and based on it, preventive and corrective measures are proposed together in an impact mitigation management system based in flow charts that will serve to more easily apply and control these measures, in order to prevent them from causing significant or irreversible damage to the environment. …”
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Integrating CT-based radiomics and clinical features to better predict the prognosis of acute pancreatitis by Hang Chen, Yao Wen, Xinya Li, Xia Li, Liping Su, Xinglan Wang, Fang Wang, Dan Liu

“…Conclusions CT-based radiomics incorporating clinical features was superior to other models in predicting AP prognosis, which may offer additional information for AP patients at higher risk of developing poor prognosis. Critical relevance statement Integrating CT radiomics-based analysis of pancreatic and peripancreatic features with clinical risk factors enhances the assessment of AP prognosis, allowing for optimal clinical decision-making in individuals at risk of severe AP. …”
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Self-reported knowledge and difficulties towards palliative care among healthcare professionals in rural China: a cross-sectional study by Junwei Niu, Min Feng, Changhui Song, Hui Xie

“…Conclusions This study highlights critical gaps in rural China’s PC services, including inadequate training, limited focus on spiritual needs and death education, and disparities in insurance coverage. …”
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Gait-based Parkinson’s disease diagnosis and severity classification using force sensors and machine learning by Navita, Pooja Mittal, Yogesh Kumar Sharma, Anjani Kumar Rai, Sarita Simaiya, Umesh Kumar Lilhore, Vimal Kumar

“…It is acknowledged that the early detection of Parkinson’s disease is contingent upon critical parameters, including stride length, stance duration, swing interval, double limb support, step time, and step length. …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Our findings lay the groundwork for further investigation of the therapeutic scope of NRTIs and the mechanisms underlying their anti-inflammatory effects across non-retroviral infectious diseases.IMPORTANCEInflammatory responses are critical for host control of bacterial infection, but excessive inflammation can damage host tissues and lead to sepsis. …”
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Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma by Lanhua Wu, Liang Li, Mingjing Zhu, Ziyan Zhou, Xuejin Su, Yueming Jiang, Min Kang, Li Jiang

“…H2B clustered histone 9 (H2BC9), a member of the H2B family, plays critical roles in gene expression regulation, chromosome structure, DNA repair stability, and cell cycle regulation. …”
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DIGITALIZATION OF THE ECONOMY AS THE BASIS OF HUMAN CAPITAL POTENTIAL by Ahmadova Akima Amir, Rzayev Mirza Agharza, İsmayilova Lala Hamlet, Muradova Jala Nizami

“…Digitalization of the economy is critically important in the era of global changes in the modern world. …”
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Multispectral, Thermal, and Hyperspectral Sensing Data Depict Stomatal Conductance in Grapevine by Kesevan Veloo, Carlos Zúñiga Espinoza, Alberto Espinoza Salgado, Pete W. Jacoby, Sindhuja Sankaran

“…In such scenarios, conservation of water using different approaches, including subsurface irrigation, becomes critical. Detecting crop water status becomes key to evaluating and managing such approaches. …”
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Evaluation of Delay Characteristics at A 4- Legged Signalised Intersection for Improvement in The Level of Service. A Case Study of Jinja Road Intersection. by Babirye, Joanitor

“…Intersections are a critical aspect of street design as the point where motorist, bicycle, and pedestrian movements converge. …”
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Effect of Gender Equality on Economic Development of Household Heads in Uganda: A Case Study of Rwamucucu Sub-County, Rukiga District. by Nsimire, Millicent

“…The objectives of the study included the following: to investigate the cause of gender equality economic development of household heads in Rwamucucu sub-county, Rukiga district, to find out the effects of gender equality on economic development of household heads of Rwamucucu sub-county, Rukiga district and to identify possible solutions that have been suggested on economic development of household heads of Rwamucucu sub-county, Rukiga district. There was critical review of the issues that have explored and studied both theoretically and empirically in the existing literature on of gender equality as an independent variable economic development as the dependent variable and the methods of data collection were put into action. …”
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