Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization by Lu Ding, Bo Chen, Zhou Zhou, Zhaojun Mei, Kan Cao, Xinyu Lu, Wei Chen

“…ER-related signaling pathways and the regulation of DNA damage may play a critical role in the pathogenesis of both diseases.…”
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FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers by Yongchang Tang, Hong Wang, Jiankun Zhang, Chunhui Yang, Fei Xu, Yan Song, Tianen Li, Qiangbo Zhang

“…Abstract The crosstalk between cancers and the immune microenvironment plays a critical role in malignant progression. FMS-like tyrosine kinase 3 (FLT3) is a frequently mutated gene in acute myeloid leukemia (AML). …”
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Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR by Liang Cao, Wen Jun Pi, Qiang Zhang, Qing Li

“…Aberrant patterns of 5-methylcytosine (m5C)-based ribonucleic acid (RNA) methylation have critical roles in various human diseases, but their importance in spinal cord injury (SCI) is largely unknown. …”
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Temporal and Spatial Characteristics and Influencing Factors of Carbon Storage in Black Soil Area Under Topographic Gradient by Zhaoxue Gai, Wenlu Zheng, Bonoua Faye, Hongyan Wang, Guoming Du

“…The spatial pattern of carbon storage varies significantly under different topographic gradients from 1990 to 2020. The most critical driving factors influencing the spatial distribution pattern of carbon storage were land use and annual average temperature. …”
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Diagnostic Accuracy of Mammography, Ultrasound, and Fine-Needle Aspiration in Detecting Breast Cancer in Patients with Painful Breast Masses:A Medical Record-Base Study by Hassan Vafapour, Sajad Borzoueisileh, Fatemeh Vafapour, Zafar Masoumi Moghaddam, Frough Nikeghbali, Yaghoub Barfar, Amir Hekmatifar

“…Breast cancer is a prevalent malignant tumor, and early detection is critical for successful treatment. Diagnostic methods include physical examination, mammography, ultrasound, magnetic resonance imaging (MRI), and fine-needle aspiration (FNA). …”
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Health-Related Quality of Life Subdomains in Patients with Parkinson’s Disease: The Role of Gender by Anja Ophey, Carsten Eggers, Richard Dano, Lars Timmermann, Elke Kalbe

“…However, both the dimensionality of the eight PDQ-39 subscales and their summary score recently faced criticism. Furthermore, data on disease-related and neuropsychological determinants and the role of gender on HrQoL in PD are inconclusive yet. …”
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Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p. by Shengjuan Lu, Lin Zeng, Guojun Mo, Danqing Lei, Yuanhong Li, Guodi Ou, Hailian Wu, Jie Sun, Chao Rong, Sha He, Dani Zhong, Qing Ke, Qingmei Zhang, Xiaohong Tan, Hong Cen, Xiaoxun Xie, Chengcheng Liao

“…Our findings indicate SNHG17 as critical for promoting DLBCL progression by regulating the EZH2 signaling pathway and sponging miR-34a-5p. …”
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Optimal aspiration pressure of suction pump for oocyte retrieval in infertile patients undergoing in vitro fertilization. by Sung Woo Kim, Hye Yun Kim, Ji Yeon Han, Hoon Kim, Seung-Yup Ku

“…<h4>Background</h4>The oocyte retrieval is a critical step in assisted reproductive technologies, including in vitro fertilization and fertility preservation. …”
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A headspace-gas chromatography method for isopropanol determination in warfarin sodium products as a measure of drug crystallinity by Rahman Ziyaur, Akhtar Sohail, Siddiqui Akhtar, Ciavarella Anthony B., Nguyenpho Agnes, Faustino Patrick J., Khan Mansoor A.

“…Coumadin® a nd s everal generic products of warfarin s odium (WS) contain the crystalline form (clathrate) in which WS and isopropanol (IPA) are associated in a 2:1 molar ratio. IPA is critical in maintaining the WS crystalline structure. …”
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Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked to Solanum mauritianum scope: Discovery of antibacterial and anticancer properties by Abraham Goodness Ogofure, Ezekiel Green

“…This study provides critical insights into the microbial diversity of S. mauritianum and underscores the potential of its endophytic bacteria as sources of bioactive compounds with diverse biotechnological applications.…”
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Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…Risk of bias assessment with RoB2 was low to high and ROBINS-1 was moderate to critical. Conclusion This was the first comprehensive scoping review of unintended side effects of cannabis in Otolaryngology. …”
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Comparison of the risk of obesity in the FTO rs9939609 genotype in a multiethnic group in Asia systematic review and meta-analysis by Donna Pratiwi, Miko Sidartha, Elvan Wiyarta, Elvan Wiyarta, I Wayan Agustinus Harimawan, Ni Made Dwi Asti Lestari, Bonglee Kim, Nurpudji Astuti Taslim, Trina Ekawati Tallei, Fahrul Nurkolis, Rony Abdi Syahputra

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A community-based father education intervention on breastfeeding practice in Ethiopia: a quasi-experimental study by Wolde Melese Ayele, Tesfaye Birhane Tegegne, Asnakew Molla Mekonen

“…The government and healthcare workers should implement policies supporting father-inclusive breastfeeding initiatives such as creating awareness and the critical role fathers’ play.…”
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Investigating Fire Collapse Early Warning Systems for Portal Frames by Ming Xie, Fangbo Xu, Zhangdong Wang, Li’e Yin, Xiangdong Wu, Mengqi Xu, Xiang Li

“…Due to the complexity of an actual fire, it is difficult to accurately predict the critical temperature of fire−induced instability in columns and the failure mode after the instability, and there are deviations in the collapse warnings. …”
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Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle by Ju Qiu, Zheng Ma, Zhipeng Hong, Xu Yin, Yun Chen, Hafiz Qadeer Ahmed, Linsen Zan, Anning Li

“…Abstract Background Muscle and adipose tissue are the most critical indicators of beef quality, and their development and function are regulated by noncoding RNAs (ncRNAs). …”
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Trauma surgical skill sustainment at the University of Chicago AMEDD Military-Civilian Trauma Team Training Site: an observation report by Priya Prakash, Kenneth Wilson, Jennifer Cone, Selwyn O Rogers, Andrew Benjamin, Timothy P Plackett, Nicholas Jaszczak, David A Hampton

“…Abstracted data included tasks met under the Army’s Individual Critical Task List (ICTL) for general surgeons. The Knowledge, Skills, and Abilities (KSA) score was estimated based on previously reported point values for procedures. …”
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Seroprevalence of Hepatitis C Viral Infection in Ethiopia: A Systematic Review and Meta-Analysis by Teshiwal Deress, Yihenew Million, Teshome Belachew, Mohabaw Jemal, Mekonnen Girma

“…Strengthening the scope of existing prevention and control programs and implementing novel approaches, including screen-and-treat, could significantly help to tackle this critical public health issue. The study provides a current estimate which is valuable for policymakers and other responsible bodies.…”
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Fostering transformative learning and whole patient care among teaching hospital staff through artistic creation: a qualitative study by Kang-Ju Chou, Ying-Yao Cheng, Wen Cheng, Hsueh-Hua Chuang, Chun-Teng Tsai, Hua-Chang Fang

“…Conclusions Our results align with Mezirow’s phases of TL, with art creation highlighting key phases such as self-examination and critical reflection. Physicians showed greater engagement in these phases than other professionals. …”
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Cardiometabolic index as a predictor of gallstone incidence in U.S. adults: insights from NHANES 2017–2020 by Ji Li, Shou-jun Bai

“…These findings underscore the importance of CMI as a critical risk factor and emphasize the necessity of targeted interventions for high-risk populations.…”
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Finite element stress analysis to evaluate and compare the effect of splinting in periodontally compromised teeth having 55 % bone loss with different materials by Shivangi Joshi, Prakash Talreja, Prajakta Rao, Nilesh Joshi, Vinayak Thorat, Ruhi Mohta

“…Conclusion: The study highlights the critical role of splint material in reducing stress on the PDL of periodontally compromised teeth. …”
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