Multimodality imaging features of systemic amyloidosis: a case report by Yi Yu, Zhi-Chao Li, Guang-Yin Li, Ting Wang, Yi-Gang Li

“…The utility of echocardiographic features such as reduced GLS and abnormal ECG findings emerges as critical in early identification of myocardial amyloidosis. …”
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Machine Learning and Intelligent Diagnostics in Dental and Orofacial Pain Management: A Systematic Review by Taseef Hasan Farook, Nafij Bin Jamayet, Johari Yap Abdullah, Mohammad Khursheed Alam

“…The risk of bias was assessed by JBI-DTA critical appraisal, and certainty of the evidence was evaluated using the GRADE approach. …”
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Outpatient chemotherapy drug costs and expensive chemotherapy drug use in 340B and Non-340B hospitals: an observational study by Jianhui Hu, David R. Nerenz

“…Abstract Background The 340B Drug Pricing Program has been controversial since its inception in 1992, a major criticism being that 340B hospitals use more outpatient drugs, and more expensive drugs, because of financial incentives to “make money” through the program. …”
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Multistate Markov model application for blood pressure transition among the Chinese elderly population: a quantitative longitudinal study by Bin Zhao, Juan Xiong, Yuxin Wang, Xujuan Zheng, Yiqin Zhang, Liping Xu, Lina Zhou

“…Increasing age, BMI and glucose were critical risk factors for developing hypertension. …”
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Rapid Detection of microRNA-122 in Serum and Finger Blood Using a Lateral Flow Nucleic Acid Biosensor by Min Zhang, Meijing Ma, Jiahui Wang, Yurui Zhou, Xueji Zhang, Guodong Liu

“…An expanding body of research has demonstrated that miR-122 is a critical regulator in both the initiation and progression of a wide range of liver diseases. …”
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The effect of Baby-Friendly Hospital Initiative compliance on the association between mode of birth and breastfeeding initiation in Sri Lanka by Laavanya Lokeesan, Elizabeth Martin, Rebecca Byrne, Yvette D. Miller

“…Conclusions Improving compliance with mother-baby skin-to-skin contact (BFHI Step 4) and no supplementation (BFHI Step 6) is critical for Sri Lankan health services to support all women to establish breastfeeding initiation within one hour of birth, as these practices attenuate the negative effect of caesarean section on breastfeeding initiation.…”
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Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry by Prasad T. Oommen, Tilmann Kallinich, Juergen Rech, Norbert Blank, Julia Weber-Arden, Jasmin B. Kuemmerle-Deschner

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Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates depression-like behaviour in female mice after a mild chronic stress paradigm by Christa Hohoff, Nicole Kerkenberg, Mingyue Zhang, Weronika Palkowska, Lydia Wachsmuth, Maja Peng, Lena Stiehl, Christiane Schettler, Johannes C. S. Zang, Andreas Huge, Evgeni Ponimaskin, Cornelius Faber, Bernhard T. Baune, Weiqi Zhang

“…ZDHHC7 might modulate also the response to CS via palmitoylation of sex steroid hormone receptors and other proteins critical for neuronal structure and functions. Therefore, we aimed to investigate the role of ZDHHC7 in response to CS on different system levels in a mouse model of Zdhhc7-deficiency. …”
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An analysis of observed and predicted extreme heat and precipitation trends across four pulse producing regions in North America: North Dakota, Montana, Saskatchewan, and Northeast... by Sophia Weiss, Erin Coughlan de Perez

“…As the demand for plant-based proteins, like pulse crops, continues to grow, it is critical to understand the impact of climate change on crop production. …”
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Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis by Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao

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A Novel Approach to Optimize Key Limitations of Azure Kinect DK for Efficient and Precise Leaf Area Measurement by Ziang Niu, Ting Huang, Chengjia Xu, Xinyue Sun, Mohamed Farag Taha, Yong He, Zhengjun Qiu

“…Maize leaf area offers valuable insights into physiological processes, playing a critical role in breeding and guiding agricultural practices. …”
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Climate change and urban forests: generational differences in women’s perceptions and willingness to participate in conservation efforts by Rahim Maleknia, Raluca Elena Enescu, Tayebeh Salehi

“…Urban forests, as a vital form of natural infrastructure, play a critical role in mitigating the adverse impacts of climate change. …”
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Spatial and temporal predictability drive foraging movements of coastal birds by Madeleine Foley, Kimberly A. Lato, Matthew Fuirst, Richard R. Veit, Robert M. Cerrato, Lesley H. Thorne

“…Abstract Background Temporal and spatial predictability of food resources are critical to the foraging efficiency of central place foragers. …”
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Spatiotemporal dynamics and prevention strategies of cervical cancer incidence in Addis Ababa, Ethiopia: an ecological study by Mathewos Assefa, Eva Johanna Kantelhardt, Teferi Gedif Fenta, Tariku Shimels

“…To address these challenges, the implementation of school-based human papillomavirus vaccination programmes, alongside targeted interventions, active campaigns and sustained surveillance, is critical. These strategies are essential to effectively reduce the cervical cancer burden and improve health outcomes in the community.…”
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Impact of changes in primary care attachment: a scoping review by Kamila Premji, Leanda Godfrey, Antoine St-Amant, Jonathan Fitzsimon

“…Two researchers conducted all stages of screening, and study quality was assessed using JBI critical appraisal tools. Key themes included causes of attachment change, direction of change and outcomes aligned with the quintuple aim framework. …”
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RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells by Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M

“…Importantly, the inhibition of autophagy appears to be a critical component of SPP86’ s mode of action, with the modulation of autophagic processes influencing the cytotoxicity against melanoma cells.Conclusion: These promising findings suggest that SPP86 is a potential drug candidate for the treatment of melanoma, warranting further research and development.Keywords: melanoma, SPP86, autophagy, DNA damage, apoptosis, PI3k/AKT…”
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Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach by Sravanthi Gandu, Kumaraswamy Gandla, Lalitha Repudi

“…This study presents the development and validation of a sensitive LC-MS/MS method for the simultaneous quantification of tadalafil and macitentan in rat plasma, enabling detailed pharmacokinetic profiling following single-dose administration. Optimization of critical parameters, including organic phase composition (50% acetonitrile), flow rate (1.0 mL/min), and pH (3.2), was achieved using a Box-Behnken Design, ensuring accurate separation and quantification. …”
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Status of fish health management and biosecurity measures in fish farms, cages and hatcheries in Western Kenya by Domitila Kyule-Muendo, Elick Otachi, Fonda Awour, Erick Ogello, Kevin Obiero, Jacob Abwao, Cecilia Muthoni, Jonathan Munguti

“…Abstract Background Aquaculture is one of the critical sectors contributing to food and nutrition security, income and employment opportunities to millions of people, and is currently the fastest growing food-producing sector globally. …”
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Type of arrhythmias and the risk of sudden cardiac death in dialysis patients: a systematic review and meta-analysis by Subhash Chander, Ahmad Bin Aamir, Rabia Latif, Om Parkash, F. N. U. Sorath, Sam Tan, Abhi Chand Lohana, Sheena Shiwlani, Mohammed Yaqub Nadeem

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A hybrid fuzzy decision-making approach for evaluating the suppliers based on industry 5.0 and viable supply chain dimensions: a case study in medical devices manufacturing by Zeinab Asadi, Hassanali Aghajani, Mohammad Valipourkhatir, Erfan Babaee Tirkolaee

“…In this regard, the medical devices industry has played an important role in crisis management and providing healthcare and has faced several major challenges in supplying raw materials, production activities, and distribution activities due to the disruptions caused by the pandemic. One of the critically important issues in the medical devices supply chain is supplier selection. …”
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