Systematic underestimation of type-specific ecosystem process variability in the Community Land Model v5 over Europe by C. Poppe Terán, C. Poppe Terán, C. Poppe Terán, B. S. Naz, B. S. Naz, H. Vereecken, H. Vereecken, R. Baatz, R. A. Fisher, H.-J. Hendricks Franssen, H.-J. Hendricks Franssen

“…<p>Evapotranspiration (ET) and gross primary production (GPP) are critical fluxes contributing to the energy, water, and carbon exchanges between the atmosphere and the land surface. …”
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Content and face validity in virtual reality with children: a validation in five steps+1 of a wheelchair basketball game by Imanol Ceberio, Mohammad Al-Rashaida, Maitane García, Juan Francisco Lopez Paz, Monika Salgueiro, Nicole Passi, Humberto Pavel, Imanol Amayra

“…In this sixth step, the ages 7–8 years versus 10–11 years showed significant differences in validity. The study also criticized the face validity cut-offs often used in adult-focused research, emphasizing the need to adapt them for children´s developmental stages.ConclusionThis study proposes a sixth step not traditionally included in content and face validity processes, specially focusing on the child user. …”
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Decarbonization and technology cost drivers: considerations for potential future thermoelectric water use in the power sector by Stuart Cohen, Raquel Valdez, Vincent Tidwell, Saroj Khanal, Thushara Gunda

“…Such assessments will be critical for ensuring decarbonization and other infrastructure-oriented investments lead to a reliable and resilient power grid.…”
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SOCIAL AND ECONOMIC DEVELOPMENT OF MAGADAN: FROM A PLANNED ECONOMY TO A MARKET ECONOMY (1960–2020) by Natalya V. Galtseva, Oksana S. Favstritskaya, Olga A. Sharypova

“…Although northern cities are relatively younger than their central and southern counterparts, they serve as strategic hubs for the development of critical territories, including the Arctic. One such city is Magadan, located in the Russian Far East. …”

A suite of wildlife crossing structures facilitates mammal movement across tropical forest fragments in a city by Li Si Tay, Ruisheng Choo, Max D. Y. Khoo, Eunice Kong, Yi Xiang Chan, Wivian H. Y. Neo, Sebastian Ow, Yuet Hsin Toh, Han Ling, Malcolm C. K. Soh, Benjamin P. Y.‐H. Lee, Adrian H. B. Loo, Kenneth B. H. Er

“…Fourteen mammal species were detected across all crossing types, with wild boar (Sus scrofa) being the most prevalent species (68.2%). Locally critically endangered species such as the Malayan porcupine (Hystrix brachyura), Sunda pangolin (Manis javanica), and Raffles' banded langur (Presbytis femoralis femoralis) were also recorded to use culverts, roads, and rope bridges for crossings, respectively. …”
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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of... by Andrew Clegg, James Wason, Miles Witham, Nina Wilson, Claire J Steves, Helen C Hancock, Avan A P Sayer, Leanne Marsay, Claire McDonald, Thomas von Zglinicki, Katherine J Rennie, Penny Bradley, Stephen Connolly, Shaun Hiu, Laura Robertson, Laura Simms, Alison J Steel, Bryony Storey

“…Finding alternatives is critical to alleviate the burden of adverse outcomes associated with sarcopenia and physical frailty. …”
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MultiTax-human: an extensive and high-resolution human-related full-length 16S rRNA reference database and taxonomy by Zhiwei Bao, Bin Zhang, Jianhua Yao, Ming D. Li

“…ABSTRACT Considering that the human microbiota plays a critical role in health and disease, an accurate and high-resolution taxonomic classification is thus essential for meaningful microbiome analysis. …”
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Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity by Tomoko Ohtani, Shinji Kuroda, Nobuhiko Kanaya, Yoshihiko Kakiuchi, Kento Kumon, Masashi Hashimoto, Chiaki Yagi, Ryoma Sugimoto, Satoru Kikuchi, Shunsuke Kagawa, Hiroshi Tazawa, Yasuo Urata, Toshiyoshi Fujiwara

“…In conclusion, tumor-derived exosomes play a significant role in DC maturation following OBP-702 treatment and are critical for the systemic activation of antitumor immunity, leading to the abscopal effect.…”
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The MADS-Box Transcription Factor ClAG2 Is a Key Regulator for the Formation of Double Flower in <i>Clematis</i> L. by Xuerong Chen, Ping Zhou, Nanhong Guo, Yiping Zheng, Xiumei Hou, Lihui Zeng

“…Flower morphology is a critical ornamental trait in flowering plants. Elucidating the molecular mechanisms underlying flower development is essential for the breeding of diverse ornamental plant cultivars. …”
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Identifying Factors Influencing Urban Bus Drivers’ Distraction: A Qualitative Study in Tehran, Iran by Fatemeh Sadat Mirnajafi Zadeh, Mojtaba Khosravi Danesh, Ali Nahvi, Abbas Rahimi Foroushani, Mohammad Javad SheikhMozafari, Adel Mazloumi

“…This issue is particularly critical in the public transport sector, especially among urban bus drivers, as distraction can lead to serious injuries and fatalities. …”
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Impact of commercial gut health interventions on caecal metagenome and broiler performance by Gladys Maria Pangga, Banaz Star-Shirko, Androniki Psifidi, Dong Xia, Nicolae Corcionivoschi, Carmel Kelly, Callie Hughes, Ursula Lavery, Anne Richmond, Umer Zeeshan Ijaz, Ozan Gundogdu

“…Abstract Background Maintaining gut health is a persistent and unresolved challenge in the poultry industry. Given the critical role of gut health in chicken performance and welfare, there is a pressing need to identify effective gut health intervention (GHI) strategies to ensure optimal outcomes in poultry farming. …”
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Sustainable aquaculture and sea ranching with the use of vaccines: a review by Alma Alfatat, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Muhammad Fachri, Hagai Nsobi Lauden, Shaoliang Lyu, Xuefeng Wang, Sahya Maulu, Berchie Asiedu, Syaifiuddin Syaifiuddin

“…As aquaculture takes on a major role in global seafood production, the industry has encountered several hurdles, notably in disease management and overharvesting in natural habitats challenges. Vaccination is a critical component of immunological preventive strategy essential for the health management of animals. …”
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Completion of the Central Italy daily precipitation instrumental data series from 1951 to 2019 by Gamal AbdElNasser Allam Abouzied, Guoqiang Tang, Simon Michael Papalexiou, Martyn P. Clark, Eleonora Aruffo, Piero Di Carlo

“…Abstract Precipitation is a critical part of the global hydrological cycle that determines the distribution of water resources. …”
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Investigation and analysis of clinical medical undergraduate learning behaviors under different teaching models by Yang-Zheng Lan, Yang-Zheng Lan, Wen-Ting Lin, Zheng Wu, Zheng Wu, Wen-Jia Chen, Wen-Jia Chen, Dan Guo, Shu-Hui Liu, Shu-Hui Liu, Jing Liu, Jing Liu

“…Medical education plays a critical role in preparing future doctors, responsible for the well-being and health of individual patients. …”
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Categorization of early embryonic malformations in broilers by a new classification method combining light microscopy and high-resolution Episcopic Microscopy by Yuval Cinnamon, Natalia Slutsky, Maxim Quint, Olga Genin, Dalit Sela-Donenfeld

“…These early days are critical, as malformations acquired during this period may severely affect growth and development of both the embryo and the hatchling chick. …”
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Role of Astrocytic Dysfunction in the Pathogenesis of Parkinson’s Disease Animal Models from a Molecular Signaling Perspective by Lucas Udovin, Cecilia Quarracino, María I. Herrera, Francisco Capani, Matilde Otero-Losada, Santiago Perez-Lloret

“…Despite the fact that astrocytes are the most abundant glial cells, critical for brain function, few studies have dealt with their possible role in neurodegenerative diseases like Parkinson’s disease (PD). …”
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Multi-omics integration and immune profiling identify possible causal networks leading to uterine microbiome dysbiosis in dairy cows that develop metritis by S. Casaro, J. G. Prim, T. D. Gonzalez, F. Cunha, A. C. M. Silva, H. Yu, R. S. Bisinotto, R. C. Chebel, J. E. P. Santos, C. D. Nelson, S. J. Jeon, R. C. Bicalho, J. P. Driver, Klibs N. Galvão

“…An effective immune response is critical for maintaining uterine health. Nonetheless, periparturient cows experience immune dysregulation, which seems to be intensified by prepartum over-condition. …”
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Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae by Tien-Huang Lin, Chen-Yu Wang, Chien-Chen Wu, Ching-Ting Lin

“…Conclusion: Our findings highlight the critical role of the Pta-AckA pathway in K. pneumoniae pathogenesis. …”
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Integrated metabolome and transcriptome analysis reveals potential mechanism during the bud dormancy transition of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsi... by Huan Guan, Huan Guan, Yuhuan Zhao, Yuhuan Zhao, Qing Chen, Qianqian Zhang, Qianqian Zhang, Pengpeng Yang, Pengpeng Yang, Shuying Sun, Shuying Sun, Guilin Chen, Guilin Chen

“…The transcription factors MYB, ERF, bHLH, zinc finger, and MADS-box may regulate the genes involved in hormone signal transduction and starch and sucrose metabolism, which are critical for regulating the transition from endo- to ecodormancy in AMM buds. …”
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Conceptualising cultural safety at an Indigenous-focused midwifery practice in Toronto, Canada: qualitative interviews with Indigenous and non-Indigenous clients by Michelle Firestone, Sara H Wolfe, Cheryllee Bourgeois, Janet K Smylie, Mackenzie E Churchill, Helle Moeller

“…Interviews were transcribed and analysed thematically using an iterative, consensus-based approach and a critical, naturalistic, and decolonising lens.Participants Saturation was reached after 20 interviews (n=9 Indigenous participants, n=11 non-Indigenous participants).Results Three domains of cultural safety emerged. …”
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