Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis by Hongbin Luo, Qunya Zheng, Youzheng Zhou, Weipeng Lai, Nanwen Zhang, Peng Chen

“…Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA). …”
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Corrosion Mitigation with Chemical Injection in Welded Carbon Steel Pipe for Offshore Water Treatment Plant by Henry Ekene Mgbemere, Johnson Olumuyiwa Agunsoye, Kenechi Ijeoma Ojemeni, Obianuju Vivian Izuegbu

“…This research has the potential to significantly impact offshore water treatment, providing valuable insights into the challenges and potential solutions for corrosion mitigation in this critical area. …”
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The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation. by Mathieu F Chevalier, Gaël Petitjean, Catherine Dunyach-Rémy, Céline Didier, Pierre-Marie Girard, Maria Elena Manea, Pauline Campa, Laurence Meyer, Christine Rouzioux, Jean-Philippe Lavigne, Françoise Barré-Sinoussi, Daniel Scott-Algara, Laurence Weiss

“…Impairment of the intestinal barrier and subsequent microbial translocation (MT) may be involved in chronic immune activation, which plays a central role in HIV pathogenesis. Th17 cells are critical to prevent MT. The aim of the study was to investigate, in patients with primary HIV infection (PHI), the early relationship between the Th17/Treg ratio, monocyte activation and MT and their impact on the T-cell activation set point, which is known to predict disease progression. 27 patients with early PHI were included in a prospective longitudinal study and followed-up for 6 months. …”
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Enhancing technological sustainability in academia: leveraging ChatGPT for teaching, learning and evaluation by Labaran Isiaku, Abubakar Sadiq Muhammad, Hyelda Ibrahim Kefas, Fitzgerald Chidozie Ukaegbu

“…Findings – The study indicates that ChatGPT can have a significant impact on personalized learning, lesson planning, providing feedback, creating study materials, generating quizzes and exam questions, supporting language learning, offering virtual teaching assistance, tutoring and fostering critical thinking. However, it also sheds light on the ethical issues and challenges associated with its use, including privacy and data protection, transparency and alignment with educational principles. …”
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Efficacy and safety of non-pharmacological interventions for neonatal pain: an overview of systematic reviews by Xufei Luo, Qiao Shen, Zixuan Huang, Hongyao Leng, Xianlan Zheng

“…Based on AMSTAR 2, seven reviews were found to be of ‘high quality‘, eight of ‘moderate quality’, five of ‘low quality’ and nine of ‘critically low quality’. The GRADE results suggested that facilitated tucking, kangaroo care, sweet solutions, familiar odour or combined non-pharmacological interventions, such as a combination of sucrose and non-nutritive sucking, were effective and safe in reducing pain from medical procedures in neonates. …”
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“The Founder and Father of his Empire”: Voltaire on the Peace of Nystad and the Imperial Status of Russia by S. A. Mezin

“…According to Voltaire, the specific feature of the Russian Empire, created by Peter I, lies in the fact that it was a self-civilizing empire, bringing enlightenment on the neighboring «barbaric» peoples.The author of the paper, reviewing specific cases, arrives at a conclusion, that Voltaire’s works of high confidence for their time took a worthy standing in the world historiography of the Petrine era, due to a wide range of sources, the historian’s ability for their critical assessment, his seeking to maintain a certain evaluation independence in the description of events from different perspectives, his commitment to historical truth, his talent of a writer.The work is carried out within the project, aimed at publishing a first complete scientific edition of «The History of the Russian Empire under Peter the Great» in Russian.…”
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Distribution of energy in propagation for ocean extreme wave generation in hydrodynamics laboratory by D. Fadhiliani, M. Ikhwan, M. Ramli, S. Rizal, M. Syafwan

“…The Hamiltonian formula that describes the phenomenon of phase singularity is used to observe energy. This data is critical in determining the parameters used to generate extreme waves.METHODS: The envelope of the Benjamin Bona Mahony wave group can be used to study the Benjamin Bona Mahony wave. …”
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Dynamic Connectivity Hub: Multiple ISPs Smart Aggregation for Optimized IoT Connectivity by Hany Ali, Mohamed A. Abouelatta, Khaled Y. Youssef

“…As IoT ecosystems grow increasingly complex, multiple Internet Service Providers (ISPs) aggregation and dynamic traffic optimization have become critical for ensuring reliable, cost-effective, and high-performance network services. …”
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Hypercapnic Ventilatory Response in the Weaning of Patients with Prolonged Mechanical Ventilation by Chung-Shu Lee, Ning-Hung Chen, Li-Pang Chuang, Chih-Hao Chang, Li-Fu Li, Shih-Wei Lin, Hsiung-Ying Huang

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Optimizing Solid Oxide Fuel Cell Performance Using Advanced Meta-Heuristic Algorithms by Siva Ram Rajeyyagari, Srinivas Nowduri

“…The background of this research is rooted in the need for enhanced SOFC efficiency and reliability, which are critical for sustainable energy solutions. Our approach utilizes a Radial Basis Function (RBF) neural network trained with experimental data encompassing five input parameters: oxygen concentration, operating temperature, instrumentation, electrolyte thickness, and electrical current, with the goal of optimizing the single output parameter of power. …”
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Protein palmitoylation is involved in regulating mouse sperm motility via the signals of calcium, protein tyrosine phosphorylation and reactive oxygen species by Yuping Xiong, Chenchen Yi, Haixia Zheng, Ya Ni, Yamei Xue, Kun Li

“…Abstract Background Protein palmitoylation, a critical posttranslational modification, plays an indispensable role in various cellular processes, including the regulation of protein stability, mediation of membrane fusion, facilitation of intracellular protein trafficking, and participation in cellular signaling pathways. …”
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Cross-Modal Augmented Transformer for Automated Medical Report Generation by Yuhao Tang, Ye Yuan, Fei Tao, Minghao Tang

“…Prior investigations often overlook this critical aspect, primarily relying on traditional image captioning frameworks initially designed for general-domain images and sentences. …”
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WeARTolerance: Evaluating the impact of an arts-based program to reduce mental health-related stigma in young people. by Ana Beato, Leonor Pereira da Costa, Ana Carvalho, Sara Albuquerque, Isabel Santos

“…The invisibility of mental health issues highlights the critical need for improved knowledge and stigma reduction, underscoring the urgency of tackling this issue. …”
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ADVANCING UNDERSTANDING OF SERVICE-LEARNING: A CASE STUDY OF A UNIVERSITY IN MALAYSIA by Fong Wei Diong, Phaik Kin Cheah, Poh Chua Siah

“… Purpose – This study aims to advance the understanding of service-learning within the context of Malaysian higher education, employing multiple qualitative approaches to source information relating to student perspectives whilst critically analysing findings through triangulation. …”
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Cataract surgery in Australia: a review of the regional literature and outcomes from 5018 cases at a tertiary teaching hospital by Chameen Samarawickrama, Muhammad A Khan, Brendon W H Lee, Lauren Sartor

“…The lack of a regional cataract surgery registry represents a critical need in assessing and claiming key performance indicators, capturing emerging trends and identifying region-specific risk factors to deliver the best patient outcomes.…”
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Specialty choice among final-year medical students and house officers in Nigeria: implications for anaesthesia practice – a cross-sectional study by Thankgod Chukwunnonso Okonkwo, Gbolahan Deji Olatunji, Victor Mayowa Adeleye, Mukaila Oyegbade Akinwale

“…Anaesthesia faces particularly critical shortages. Medical graduate specialty choices have a vital impact on the workforce and are essential for healthcare planning. …”
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Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report by Weng D, Zhou H, Huang G, Cao Q, Wang H, Cao Z, Xie Q

“…It underscores the value of mNGS in identifying rare infections and emphasizes the role of TDM in optimizing antibiotic therapy, providing a reference for future cases of rare and critical infections with fever of unknown origin.Keywords: pyogenic thoracic spondylitis, metagenomic next-generation sequencing, mNGS, therapeutic drug monitoring, TDM, antibiotic therapy, fever of unknown origin…”
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Advances in the carbon-ceramic composites oxidation and ablation resistance: A review by Anna Didenko, Alexey Astapov

“…A review and critical analysis of recent advances in the field of oxidation and ablation resistance of carbon-ceramic composite materials, which are the most promising for high temperature applications in load-bearing structures and heat-protective systems of rocket and aerospace engineering, is carried out. …”
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A Model of ESG-Transparency Index in Corporate Reporting by R. P. Bulyga, M. V. Melnik, I. V. Safonova, V. B. Gisin

“…By leveraging mathematical tools, this model quantitatively measures the level of Environmental, Social, and Governance (ESG) transparency, taking into account the requirements of stakeholders and evaluating a public company's ability to disclose comprehensive information.The research hypothesis posits that assessing ESG transparency in public company reporting based solely on the "quantity" of estimated values, while neglecting the critical factors of "quality" and "reliability," undermines the accuracy and reliability of the results. …”
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Strength and durability of indirect protection against SARS-CoV-2 infection through vaccine and infection-acquired immunity by Sophia T. Tan, Isabel Rodríguez-Barraquer, Ada T. Kwan, Seth Blumberg, Hailey J. Park, Justine Hutchinson, David Leidner, Joseph A. Lewnard, David Sears, Nathan C. Lo

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