Lights and Siren Transport and the Need for Hospital Intervention in Nontrauma Patients: A Prospective Study by Olivier Bertholet, Mathieu Pasquier, Elina Christes, Damien Wirths, Pierre-Nicolas Carron, Olivier Hugli, Fabrice Dami

“…The use of lights and siren transport (LST) has been a matter of debate because of the short time savings and well-established increased risks for Emergency Medical Services (EMS) and bystanders. Time-critical hospital intervention (TCHI) denotes urgently needed procedures that cannot be performed properly in an out-of-hospital setting. …”
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ALMA Spectral Survey of an Eruptive Young Star, V883 Ori (ASSAY). II. Freshly Sublimated Complex Organic Molecules in the Keplerian Disk by Jae-Hong Jeong, Jeong-Eun Lee, Seonjae Lee, Giseon Baek, Ji-Hyun Kang, Seokho Lee, Chul-Hwan Kim, Hyeong-Sik Yun, Yuri Aikawa, Gregory J. Herczeg, Doug Johnstone, Lucas Cieza

“…According to our analyses, using only optically thin lines is critical to deriving the reliable column densities of COMs. …”
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Archival Research, Underwater Optical Surveys, and 3D Modelling: Three Stages for Shaping the Wreck of the Steamship <i>Bengala</i> (Isola di Capo Rizzuto, Crotone, Italy) by Salvatore Medaglia, Fabio Bruno, Ana Castelli, Matteo Collina, Barbara Davidde Petriaggi, Luca De Rosa, Julieta Frere, Fabrizio Fuoco, Guillermo Gutiérrez, Antonio Lagudi, Francesco Megna, Raffaele Peluso

“…Archival research, including consultation of official documents, provided critical information on the ship’s dimensions, superstructure, rigging, materials, and construction methods. …”
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Undetectable = Untransmittable (U = U): insights from people living with HIV attending health facilities in Rwanda by Pierre Gashema, Felix Ndahimana, Eric Saramba, Tumisime Musafiri, Etienne Ishimwe, Patrick Gad Iradukunda, Angelique Ingabire, Vedaste Masengesho, Sam Kanyesigye, Nadine Rujeni, Muhayimpundu Ribakare, Claude Mambo Muvunyi, Tafadzwa Dzinamarira

“…Further research is essential to better understand the challenges faced by PLWH, which is critical for achieving the UNAIDS goal of ending the HIV/AIDS epidemic by 2030.…”
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Trends and Clinical Implications of Pediatric Pulmonary Function After Hematopoietic Stem Cell Transplantation: A Systematic Review by Xiaowei Zhao, Yuqi Zhao, Guoyu Ding, Xue Li, Xiaoyue Zhang, Yanli Leng, Hongmei Wang

“…Conclusion Monitoring pulmonary function is critical for the early identification of complications in pediatric HSCT recipients. …”
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X-ray pulsed light curves of highly compact neutron stars as probes of scalar–tensor theories of gravity by Tulio Ottoni, Jaziel G. Coelho, Rafael C. R. de Lima, Jonas P. Pereira, Jorge A. Rueda

“…We focus on the high-compactness regime, i.e., close to the critical GR value $$GM/(c^2 R)=0.284$$ G M / ( c 2 R ) = 0.284 , over which multiple images of the spot appear and impact crucially the light curves. …”
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Fusion of Remotely Sensed Data with Monitoring Well Measurements for Groundwater Level Management by César de Oliveira Ferreira Silva, Rodrigo Lilla Manzione, Epitácio Pedro da Silva Neto, Ulisses Alencar Bezerra, John Elton Cunha

“…In this study, we integrated multisource data by applying the LMC to model the spatial relationships of variables and then utilized block support regularization with collocated block cokriging (CBCK) to enhance our predictions. A critical engineering challenge addressed in this study is support homogenization, where we adjusted punctual variances to block variances and ensure consistency in spatial predictions. …”
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Genomic identification, evolutionary analysis, and transcript profiling of protein phosphatase 2C in Solanum lycopersicum by Miah Mohammad Sakib, Md. Sifatul Islam, Asifur Rob Bhuya, Md. Rihan Kabir Shuvo, Mohammad Abdullah-Al-Shoeb, Muhammad Abul Kalam Azad, Ajit Ghosh

“…Abstract Protein phosphatases (PPs) are a class of enzymes that play a critical role in cellular regulation by catalyzing the removal of phosphate groups from proteins. …”
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Review of Urinary Tract Infections in Pregnancy: Risks, Complications and Management by Patrycja Kałuziak, Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Marta Jajczak, Maciej Mossakowski, Aleksandra Witek, Mateusz Litwin, Stanisław Jesionek

“…Healthcare professionals play a critical role in managing UTIs during pregnancy. Early detection through routine screening and prompt treatment is crucial for optimal outcomes. …”
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Driving brain state transitions via Adaptive Local Energy Control Model by Rong Yao, Langhua Shi, Yan Niu, HaiFang Li, Xing Fan, Bin Wang

“…However, they often neglect the critical question of how the whole brain responds to external control inputs that are driven by control energy from multiple brain regions, which limits their application value in guiding clinical neurostimulation. …”
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Influence of hypertension diagnosis and subjective life expectancy on health behaviors among middle-aged and older Chinese adults by Xiaoxiao Liu, Xiaoyi Ji, Honghong Xia, Yuxin Tian, Weihong Zheng, Linyun Fu, Peiyuan Qiu, Yang Wan

“…Therefore, there is a critical need to enhance hypertension awareness and promote healthier behaviors among both diagnosed individuals with uncontrolled blood pressure and those unaware of their hypertension.…”
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Assessing survey design changes of long-term fishery-independent groundfish trawl surveys in the Gulf of Mexico by Adam G. Pollack, Eric R. Hoffmayer, Theodore S. Switzer, David S. Hanisko, Jill M. Hendon, John Mareska, Fernando Martinez-Andrade, Jeff Rester, Zachary C. Zuckerman, Gilmore Pellegrin

“…Finally, a discussion around the lesson learned (i.e., the critical need for overlap of survey designs), emphasizing the potential impacts of these changes on the overall time series concerning stock assessments, is presented.…”
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Biomechanical Analysis of Truncated Cone Implants for Maxillary Sinus Lift: An In Vitro Study on Polyurethane Laminas by Luca Comuzzi, Tea Romasco, Carlos Fernando Mourão, Giulia Marchioli, Adriano Piattelli, Natalia Di Pietro

“…Notably, this difference was not significant at the 20 PCF/3 mm lamina, highlighting that bone density may play a more critical role than thickness for SLC implants. This study simulated the clinical condition of achieving primary stability even with extreme maxillary bone thickness. …”
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Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma by Yanfang Huang, Guoxian Luo, Xiujie Sheng, Jianqi Li

“…The LASSO regression and Nomogram models demonstrated robust predictive performance for UCEC prognosis, identifying CDKN2A, GLS, and PPAT as critical prognostic genes. Furthermore, these genes played essential roles in immune cell infiltration in UCEC, confirming their significance. …”
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Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms by M. A. Kleshchev, A. V. Maltseva, E. A. Antropova, P. S. Demenkov, T. V. Ivanisenko, Y. L. Orlov, H. Chao, M. Chen, N. A. Kolchanov, V. A. Ivanisenko

“…Drought is a critical factor limiting the productivity of bread wheat (Triticum aestivum L.), one of the key agricultural crops. …”
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Unveiling the link between NADPH oxidase 2 activation and mitochondrial superoxide formation in leukemic cell killing induced by arsenic trioxide by Andrea Spina, Andrea Guidarelli, Gloria Buffi, Mara Fiorani, Orazio Cantoni

“….-) formation induced by clinically relevant concentrations of arsenic trioxide (ATO; As2O3) in acute promyelocytic leukemia (APL) cells.Carefully controlled inhibitor studies and small interfering RNA mediated downregulation of p47phox (a component of the NOX 2 complex) expression demonstrated that, in an APL cell line, ATO promotes upstream NOX 2 activation critically connected with the formation of mitoO2.- and with the ensuing mitochondrial permeability transition (MPT)-dependent apoptosis.Instead, acute myeloid leukemia (AML) cell lines respond to ATO with low NOX 2 activation, resulting in a state that is non-permissive for mitoO2.- formation. …”
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Natremia Significantly Influences the Clinical Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Munirah M. Hasan, George Agriantonis, Navin D. Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington

“…<b>Objective</b>: Fluctuations in sodium levels (SLs) may increase mortality, severity, and prolonged length of stay (LOS) in critically ill patients. We aim to study the effect of SL on various clinical outcomes in patients with severe traumatic brain injury (TBI). …”
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DPV pUL15 possesses a potential NLS, which is important for the location of the terminase complex and for viral proliferation and genome cleavage by Qiao Yang, Yaya Feng, Lizhen Liu, Linlin Yang, Mingshu Wang, Ying Wu, Bin Tian, Xumin Ou, Renyong Jia, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Di Sun, Yu He, Zhen Wu, Ling Zhang, Yanling Yu, Anchun Cheng

“…The conserved amino acids K187, R188, and K190 are critical for the nuclear localization of pUL15, pUL28, and pUL33 but not for their interaction. …”
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Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department by Sandra Domingues, Tiago Barros, João Correia, Arlindo Cruz, Nuno Araújo, Liliana Silva

“…Effective management of acute stroke in emergency departments is critical, requiring a rapid and coordinated response to optimize clinical outcomes. …”
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Barriers to and Facilitators of Implementing Team-Based Extracorporeal Membrane Oxygenation Simulation Study: Exploratory Analysis by Joan Brown, Sophia De-Oliveira, Christopher Mitchell, Rachel Carmen Cesar, Li Ding, Melissa Fix, Daniel Stemen, Krisda Yacharn, Se Fum Wong, Anahat Dhillon

“… Abstract IntroductionExtracorporeal membrane oxygenation (ECMO) is a critical tool in the care of severe cardiorespiratory dysfunction. …”
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