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20741
Bacteria-Inspired Synthesis of Silver-Doped Zinc Oxide Nanocomposites: A Novel Synergistic Approach in Controlling Biofilm and Quorum-Sensing-Regulated Virulence Factors in <i>Pseu...
Published 2025-01-01“…Multidrug-resistant <i>Pseudomonas aeruginosa</i> infections pose a critical challenge to healthcare systems, particularly in nosocomial settings. …”
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20742
Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning
Published 2025-01-01“…Here, stDCL is developed, a dual graph contrastive learning method to identify spatial domains and interpret gene regulation in spatial transcriptomics data. stDCL adaptively incorporates gene expression data and spatial information via a graph embedding autoencoder, thereby preserving critical information within the latent embedding representations. …”
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20743
Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium
Published 2025-01-01“…Overall, these findings underscore the critical role of metabolic profiling in gaining a deeper understanding of microbial capabilities and addressing the complexities of residue composition and environmental variability.…”
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20744
Challenges of Beekeeping in Arid Regions
Published 2024-12-01“…The beekeeping sector in the Ziban region is constrained by various obstacles, with the most critical being logistical issues, a shortage of beekeeping equipment, pesticide exposure, climate change, and elevated production costs. …”
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20745
Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr...
Published 2022-07-01“…Introduction The management of diabetes has become a critical public health issue in China. The development of community-based type 2 diabetes management in China has not yet reached an ideal state, and the most suitable management methods for diabetic patients are still being explored. …”
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20746
Multi‐Instrument Investigation of the Impact of the Space Weather Events of 6–10 September 2017
Published 2021-12-01“…The total radio fade‐out lasted from 30 to 90 min at the Hermanus and Sao Luis ionosondes during the flares, while the risk level to critical ground infrastructures based on the geomagnetically induced currents hazard was very low risk. …”
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20747
Adapting to change: exploring the distribution dynamics of the alien and potentially invasive aphid species Cinara curvipes (Hemiptera: Aphididae) in the context of global warming
Published 2025-12-01“…Its high reproductive output allows the species to quickly colonise new habitats and exploit available resources, contributing to its potential invasiveness. We emphasise the critical need for collaborative engagement among researchers, stakeholders, and the public to bolster citizen science initiatives and reinforce environmental monitoring networks, all within the framework of an early detection and rapid response (EDRR) process. …”
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20748
Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients
Published 2024-01-01“…Understanding the immune response generated by SARS-CoV-2 is critical for assessing efficient therapeutic protocols and gaining insights into the durability of protective immunity. …”
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20749
Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases
Published 2025-01-01“…These findings underscore the pivotal role of mitochondrial proteins in neurodegenerative diseases, offering critical insights into disease mechanisms and potential therapeutic avenues.…”
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20750
Leadership and management skills for student nurses: a scoping review
Published 2025-01-01“…Moreover, self-awareness and understanding of personal skills were identified as critical for building confidence, fostering reflection, strategic planning, and making sound decisions. …”
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20751
Role of colour doppler ultrasound in the evaluation of hemodialysis arteriovenous access maturation and its correlation with success rate
Published 2024-12-01“…It effectively identifies critical factors such as blood flow and vein size early in the process, allowing for timely interventions to enhance dialysis outcomes. …”
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20752
Significance of the Powder Metallurgy Approach and Its Processing Parameters on the Mechanical Behavior of Magnesium-Based Materials
Published 2025-01-01“…Furthermore, PM enables precise control over critical processing parameters, such as compaction pressure, sintering temperature, and particle size, which directly influence the composite’s microstructure and properties. …”
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20753
STAT6 deficiency mitigates the severity of pulmonary arterial hypertension caused by chronic intermittent hypoxia by suppressing Th2-inducing cytokines
Published 2025-01-01“…Conclusion These findings exhibit the critical role of STAT6 in the pathogenesis of CIH induced PH by regulating Th2 immune response.STAT6 could be a significant therapeutic target for OSA-related PH.…”
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20754
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway
Published 2025-01-01“…IntroductionUlcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response. Iron is a critical fundamental element for both the maintenance of homeostasis and the mediation of inflammation in many tissues. …”
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20755
Thermodynamic qualification of knitted spacer fabrics for use as insulation box insert in the context of refrigerated transport containers in the logistics sector
Published 2023-02-01“…A thermal imaging camera was used to identify critical points for heat transfer. …”
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20756
Arbuscular mycorrhizal colonization defines root ecological strategies in an extreme arid environment
Published 2025-01-01“…These findings emphasize the critical importance of colM in modulating plant ecological strategies and highlight the need to further investigate how AM enhances root lifespan and optimizes resource uptake in extreme environments.…”
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20757
Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men
Published 2021-01-01“…AMPK/PPAR interaction is critical to regulate hepatocyte nuclear factor-4 (HNF4), a prerequisite for SHBG upregulation. …”
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20758
Machine learning-based monitoring of land cover and reclamation plantations on coal-mined landscape using Sentinel 2 data
Published 2025-02-01“…The rehabilitation of degraded coal-mined landscapes has recieved significant global attention due to its critical impact on ecological integrity, economic prosperity, and social development, aiming for zero net land degradation. …”
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20759
Exploring information technology utilization and needs in community pharmacies: a cross-sectional survey in Shanghai, China
Published 2025-02-01“…BackgroundCommunity pharmacists are critical in managing medication therapy and ensuring patient safety. …”
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20760
Remotely-sensed products capture the spatial distribution of regional carbon sequestration potential ability: A case study of Hubei Province, China
Published 2025-01-01“…Carbon neutrality has emerged as a critical issue both in China and globally, playing a significant role in mitigating climate change, protecting the environment, and enhancing energy security. …”
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