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20681
Transient dynamic analysis of cutter-head loads: effects of different cutter spacings during excavation
Published 2025-01-01“…As a critical component in achieving the rock-breaking function during the operation of Tunnel Boring Machines (TBM), the cutterhead inevitably generates significant vibrations during the rock-breaking process. …”
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20682
Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways
Published 2020-01-01“…Cytokine-induced endothelial dysfunction leads to inflammation and vascular adhesion molecule production in retinal pigment epithelium (RPE) cells. Inflammation is a critical mediator in retinal degeneration (RD) diseases, including age-related macular degeneration (AMD), and RD progression may be prevented through anti-inflammatory activity in RPE cells. …”
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20683
TEACHERS’ AND STUDENTS’ ATTITUDES TOWARDS THE USE OF ARTIFICIAL INTELLIGENCE: ALL-UKRAINIAN RESEARCH
Published 2024-12-01“…Understanding the essential role of teachers and students as active participants in this transformation, as well as the factors influencing their perceptions and attitudes toward AI, is critical. In Ukraine, the emergence and rapid spread of accessible AI tools occurred during a time of full-scale military conflict, bringing about drastic disruptions to traditional educational processes. …”
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20684
The Ability of Combined Flavonol and Trihydroxyorganic Acid to Suppress SARS-CoV-2 Reproduction
Published 2024-12-01“…The global burden of COVID-19 continues to rise, and despite significant progress in vaccine development, there remains a critical need for effective treatments for the severe inflammation and acute lung injury associated with SARS-CoV-2 infection. …”
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20685
Plant Growth and Nutritional Quality Attributes of Basella alba Applied with Variable Rates of Nitrogen Fertilizer at Different Planting Dates under Canadian Maritime Climatic Cond...
Published 2021-01-01“…Nitrogen (N) fertilization at critical planting time is important to optimize productivity and reduce nitrate accumulation in edible portions of green leafy vegetable plants. …”
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20686
The power of personas: Exploring an innovative model for understanding stakeholder perspectives in an oncology learning health network
Published 2025-01-01“…When an LHN is established, it is critical to understand the needs of all stakeholders. …”
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20687
Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil
Published 2025-01-01“…Addressing digital access, literacy inequities, and strengthening regulations are critical for the future success and equity of DHIs in public health systems. …”
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20688
The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma
Published 2021-01-01“…Our study demonstrated that the six IAG signature played a critical role in the prognosis and immunotherapy of melanoma, which might help clinicians predict patients’ survival and provide individualized treatment.…”
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20689
Prediction of clinical efficacy of acupuncture intervention on upper limb dysfunction after ischemic stroke based on machine learning: a study driven by DSA diagnostic reports data
Published 2025-01-01“…Feature importance analysis identified the M1 segment of the Middle Cerebral Artery (MCA), the origin of the Internal Carotid Artery (ICA), and the C1 segment of the ICA as the most critical factors influencing the model’s predictions. …”
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20690
Assessing Electricity Supply Reliability by Detection of Anomalies in Daily Nighttime Light
Published 2025-01-01“…Reliable electricity supply is critical to achieving Sustainable Development Goal 7 (SDG7), but it is difficult to measure and assess, especially in less developed countries and regions. …”
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20691
Surgical sharp debridement alongside maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs): A systematic review of case reports
Published 2025-03-01“…Data were extracted using a standardized form, and the quality of case reports was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports. A narrative synthesis was conducted due to the anticipated heterogeneity of the case reports, and a sensitivity analysis was performed to assess the robustness of the findings. …”
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20692
Risk Factor Analysis in Vascular Access Complications for Hemodialysis Patients
Published 2025-01-01“…<b>Background:</b> Chronic kidney disease (CKD) and renal failure remain critical global health challenges, with vascular access complications posing significant obstacles in hemodialysis management. …”
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20693
Predictive Capabilities of Corotating Interaction Regions Using STEREO and Wind In‐Situ Observations
Published 2022-07-01“…Therefore advanced warning of SIRs/CIRs is vital for mitigating the effect of space weather on critical infrastructures in modern society. Recently, several solar missions, for example, Vigil mission (Luntama et al., 2020) and Solar Ring mission (Wang et al., 2020), that can be served as a space weather monitor, have been proposed. …”
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20694
The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review
Published 2025-01-01“…The identification of reliable biomarkers for early prediction is critical for improving maternal, fetal, and neonatal outcomes. …”
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20695
Systematic identification of the chemical components of leaves and roots of Didymocarpus heucherifolius Hand.-Mazz. based on UHPLC Q-Exactive Orbitrap MS technology coupled with mo...
Published 2025-01-01“…Therefore, a rapid and accurate identification and quantification are critical in phytochemical analysis. An efficient approach based on molecular networking strategy coupled with ultra high-performance liquid chromatography coupled with Q-Exactive Orbitrap tandem mass spectrometry (UHPLC Q-Exactive Orbitrap MS) was used to analyze the chemical components systematically. …”
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20696
Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy
Published 2025-02-01“…Conclusion: This investigation illuminates the critical potential of targeting CAFs to augment immunotherapeutic approaches in prostate cancer. …”
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20697
The relationships between mental health and social media addiction, and between academic burnout and social media addiction among Chinese college students: A network analysis
Published 2025-02-01“…Results: Bridge Expected Influence results indicate that “Depression” is consistently the most central node, playing a critical role in the network connecting social media addiction, academic burnout, and psychological stress. …”
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20698
Toward 6G: An Overview of the Next Generation of Intelligent Network Connectivity
Published 2025-01-01“…Additionally, it identifies major challenges—such as advanced coding schemes, energy management, and security—and presents a roadmap for future research in these critical areas. The study also reviews potential coding and modulation techniques, such as non-binary codes and lattice codes, assessing their suitability for 6G’s stringent performance requirements. …”
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20699
Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice
Published 2025-01-01“…These results underscore the critical role of peripheral monocytes and TREM-1 in PD progression, suggesting that targeting TREM-1 could be a promising therapeutic approach to prevent dopaminergic neurodegeneration and motor dysfunction in PD. …”
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20700
Forecasting the seasonal phenology of Agrotis ipsilon in Oregon grass seed and vegetable agroecosystems
Published 2025-01-01“…Regionally specific phenological models serve as a critical component of effective areawide pest management plans to inform the timing of pest monitoring and management action. …”
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