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20281
Neglected tropical diseases in Yemen: a systematic review of epidemiology and public health challenges
Published 2025-02-01“…Prioritizing improvements in sanitation, water quality, and vector control measures, alongside community engagement, is critical. Policymakers must allocate resources effectively to address the root causes of NTDs and strengthen Yemen’s healthcare infrastructure.…”
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20282
Spread of TEM, VIM, SHV, and CTX-M β-Lactamases in Imipenem-Resistant Gram-Negative Bacilli Isolated from Egyptian Hospitals
Published 2016-01-01“…Carbapenem-resistant Gram-negative bacilli resulting from β-lactamases have been reported to be an important cause of nosocomial infections and are a critical therapeutic problem worldwide. This study aimed to describe the prevalence of imipenem-resistant Gram-negative bacilli isolates and detection of blaVIM, blaTEM, blaSHV, blaCTX-M-1, and blaCTX-M-9 genes in these clinical isolates in Egyptian hospitals. …”
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20283
NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation
Published 2022-01-01“…Toll-like receptors (TLRs) play a critical role in innate immune system responses to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). …”
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20284
Women’s experiences and expectations of intimate partner abuse identification in healthcare settings: a qualitative evidence synthesis
Published 2022-07-01“…Objectives To explore women’s experiences and expectations of intimate partner abuse (IPA) disclosure and identification in healthcare settings, focusing on the process of disclosure/identification rather than the healthcare responses that come afterwards.Design Systematic review and meta-synthesis of qualitative studiesData sources Relevant studies were sourced by using keywords to search the databases MEDLINE, EMBASE, CINAHL, PsychINFO, SocINDEX and ASSIA in September 2021.Eligibility criteria Studies needed to focus on women’s views about IPA disclosure and identification in healthcare settings, use qualitative methods and have been published in the last 5 years.Data extraction and synthesis Relevant data were extracted into a customised template. The Critical Appraisal Skills Programme checklist for qualitative research was used to assess the methodological quality of included studies. …”
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20285
A Co-Evolutionary Genetic Algorithm Approach to Optimizing Deep Learning for Brain Tumor Classification
Published 2025-01-01“…Brain tumors are among the deadliest diseases, leading researchers to focus on improving the accuracy of tumor classification—a critical task for prompt diagnosis and effective treatment. …”
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20286
Secondhand Smoke Exposure and Smoking Attitudes and Behaviors Among Adolescents in the Gaza Strip: Findings From the 2019 Global Youth Tobacco Survey
Published 2025-01-01“…Background Secondhand smoke (SHS) exposure remains a critical public health concern, especially for adolescents, who are more susceptible to its harmful effects and may initiate smoking as a result. …”
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20287
Student perspectives of equity, diversity, and inclusion in the curriculum of a UK medical school—A mixed-methods study
Published 2024-12-01“…CONCLUSION: This study emphasizes the critical need for curricular reform in medical education to prepare students for a multicultural society. …”
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20288
Analysis of whole transcriptome reveals the immune response to porcine reproductive and respiratory syndrome virus infection and tylvalosin tartrate treatment in the porcine alveol...
Published 2025-01-01“…Screening key host immune-related genetic factors in the porcine alveolar macrophages (PAMs) is critical to improve the anti-virial ability in pigs.MethodsIn this study, an in vivo model was set to evaluate the anti-PRRSV effect of tylvalosin tartrates. …”
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20289
Hybrid Random Regret Minimization and Random Utility Maximization in the Context of Schedule-Based Urban Rail Transit Assignment
Published 2018-01-01“…Route choice is one of the most critical passenger behaviors in public transit research. …”
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20290
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20291
E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model
Published 2023-01-01“…Identifying novel mechanisms regulating these processes is critical to the development of nonsurgical treatments for PAD. …”
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20292
Correlation of Aspergillus fumigatus Sensitization with Mucus Plugging in COPD
Published 2025-01-01“…Ying Luo,1,2 Jiaqi Ren,1,2 Long Liang,1,2 Jingge Qu,1,2 Chun Chang,1,2 Yongchang Sun1,2 1Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, People’s Republic of China; 2Research Center for Chronic Airway Diseases, Peking University Health Science Center, Beijing, People’s Republic of ChinaCorrespondence: Chun Chang; Yongchang Sun, Email doudou_1977@163.com; suny@bjmu.edu.cnBackground: Both Aspergillus fumigatus sensitization and mucus plugs are associated with poor clinical outcomes in COPD. …”
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20293
Optimization of meropenem continuous infusion based on Monte Carlo simulation integrating with degradation study.
Published 2024-01-01“…In-bottle stability data was subsequently integrated as input for a deterministic and stochastic simulation using a published population pharmacokinetic model of critical illness. The impact of the degradation on target attainment at 98%fT>MIC was assessed.…”
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20294
CRYβB2 alters cell adhesion to promote invasion in a triple-negative breast cancer cell line
Published 2025-01-01“…RNA sequencing analysis indicated that CRYβB2 overexpression modulated cell-cell adhesion and extracellular matrix organization pathways, which are critical to invasion of cancer cells. Specifically, CRYβB2 suppressed the expression of key cell-cell adhesion genes known as clustered protocadherins and promoted the expression of PCDH7, a nonclustered protocadherin with known oncogenic roles in various cancers. …”
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20295
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20296
Open government data in health sector: a systematic literature review
Published 2025-01-01“…The quality methodological of related studies was based on the JBI Critical Appraisal tool. Data extraction included the location of the application, description of the initiative/use of data, themes addressed, data quality, and respective evaluation tools. …”
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20297
A Comparison of Penguin Swarm Optimization Algorithms for Enhancing Network Throughput
Published 2024-12-01“…Managing and analyzing the vast amounts of data generated by smart grid devices is critical to effectively manipulating the potential of these systems. …”
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20298
Joint Task Offloading and Resource Allocation in Mobile Edge Computing-Enabled Medical Vehicular Networks
Published 2024-12-01“…In medical vehicular networks, medical vehicles can serve as efficient mobile medical service points to provide necessary and critical medical services for patients while in motion. …”
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20299
'Sanctifying Sex': Exploring 'Indecent' Sexual Imagery in Pentecostal Liturgical Practices
Published 2019-01-01“…Through an analysis of how bodies and rituals are marked by discursive practices within the songs and performances in these churches and an examination of a blasphemy case, this essay lays bare the critical spaces available for more embodied theologies - 'sexual healing' that perhaps even the worshipers themselves have unconsciously ignored. …”
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20300
Contraction ratio of multifidus and erector spinae muscles in unilateral sacroiliac joint pain: A cross-sectional trial
Published 2025-01-01“…Abstract Sacroiliac joint (SIJ) pain is one of the most prevalent reasons for disability, it affects the contraction ratio of the muscles of the back. Imaging is critical for diagnosing back muscles. The purpose of this study was to look at changes in the muscle contraction ratio of the lumbar multifidus (LM) and erector spinae (ES) in unilateral SIJ pain. …”
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