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Correlation between estimated glucose disposal rate, insulin resistance, and cardiovascular mortality among individuals with metabolic syndrome: a population-based analysis, eviden...
Published 2025-01-01“…Logistic regression analyses revealed a significant inverse correlation between eGDR and the risk of having CVD (OR:0.845, 95%CI:0.807–0.884, p < 0.01). Multivariate Cox regression analysis and restricted cubic splines analysis demonstrated that eGDR is non-linearly correlated with both the mortality of CVD (HR: 0.906, 95% CI: 0.850–0.967, p = 0.003) and all-cause mortality (HR: 0.944, 95% CI: 0.912–0.977, p = 0.001), with an identified inflection point at 5.918. …”
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1782
Impact of neutrophil percentage-to-albumin ratio on mortality in iron-deficiency anemia patients: a retrospective study using MIMIC-IV database
Published 2025-01-01“…Materials and methods We analyzed data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) 3.0 database spanning the years 2008–2022 and identified a cohort of 817 patients with IDA who met our inclusion criteria. Through multivariate Cox regression analysis, the relationship between NPAR levels and 30-day and 365-day mortality risks was assessed, and restricted cubic splines (RCS) models were used to explore potential nonlinear relationships. …”
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1783
Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database
Published 2025-01-01“…The prognostic ability of the potential biomarkers was evaluated by Cox regression and survival curve. CellMiner was used to access the correlation between the expression of potential biomarkers and anticancer drug sensitivity. …”
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1784
Pharmacological Mechanism of Zuojin Pill for Gastroesophageal Reflux Disease: A Network Pharmacology Study
Published 2022-01-01“…The findings suggest that ZJP alleviates the symptoms of GERD and improves the prognosis by regulating ROS metabolism, thereby reducing the secretion of proinflammatory cytokines like IL-1β, COX-2, CXCL8, and MMPs, regulating the expression of oncogenes such as JUN and FOS, and maintaining the normal expression of tumor suppressor genes such as TP53 and MYC. …”
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1785
Minimally Invasive Parafascicular Surgery (MIPS) for Spontaneous Intracerebral Hemorrhage Compared to Medical Management: A Case Series Comparison for a Single Institution
Published 2020-01-01“…Demographics and pre- and postclinical outcomes were compared using t-tests, the Mann–Whitney test, and chi-squared tests for continuous, ordinal and categorical measures, respectively. Cox proportional hazard models were used to estimate the time to inpatient death. …”
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1786
Association between oral microbiome diversity and all-cause mortality: a longitudinal study of NHANES, 2009–2012
Published 2024-12-01“…Objective The study investigates the association between oral microbiome diversity and all-cause mortality.Design Population-based cohort study.Setting US National Health and Nutrition Examination Survey (2009–2010 and 2011–2012).Participants A total of 8224 participants who had valid data on the oral microbiome diversity and survival through 31 December 2019 were included in this study.Primary and secondary outcome measures Oral microbiome diversity was measured using the observed number of amplicon sequence variant (ASV) and grouped into quartiles. Cox proportional hazards regression models were used to estimate the HR and 95% CI for all-cause mortality according to the quartiles of ASV number, adjusted for potential confounders.Results Among the 8224 participants (mean (SD) age: 42.0 (15.1) years; 49.9% male; 37.2% white, 23.8% black, 27.2% Hispanic and 11.8% other race/ethnicity), the median follow-up time was 108 months (IQR, 95–120 months) and 429 (5.2%) deaths were identified. …”
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1787
The association between body composition and overall survival in patients with advanced non-small cell lung cancer
Published 2025-01-01“…After adjusting for clinical variables such as gender, smoking status, clinical staging, degree of differentiation, and radiotherapy history, the multivariable Cox regression analysis showed that an increase in SFI significantly improves the overall survival rate of patients (Hazard Ratio [HR] = 1.410, 95% Confidence Interval [CI]: 1.042–1.908, P = 0.026). …”
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1788
糖代谢异常与Ⅰ期子宫内膜样腺癌临床病理及预后的相关性
Published 2021-11-01“…DM组中血糖控制不达标者(糖化血红蛋白≥7.0%)5年生存率及5年无进展生存率均低于血糖控制达标者(<italic>P</italic><0.05)。多因素COX回归分析提示,CA125水平(≥ 35 U/mL)、淋巴脉管间隙浸润(LVSI)阳性是5年生存率的独立危险因素;脂代谢异常、LVSI阳性、深肌层浸润是5年无进展生存率的独立危险因素。…”
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Down syndrome and outcomes in critically ill pediatric patients
Published 2025-01-01“…The outcomes assessed included mortality, length of stay, duration of mechanical ventilation (DMV), ventilator-free days (VFD), and healthcare-associated infections (HAI). We applied Cox regression and Poisson regression analyses to explore the relationship between Down syndrome and clinical outcomes, providing both crude and adjusted results.ResultsA total of 525 children (average age 71.3 months, range 1–218 months) were analyzed. …”
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Identification of Cytosolic DNA Sensor cGAS-STING as Immune-Related Risk Factor in Renal Carcinoma following Pan-Cancer Analysis
Published 2022-01-01“…Tumor-infiltrating immune cells (TIICs) were determined by the ssGSEA method. Kaplan–Meier curves, Cox regression analyses, and the area under the curve (AUC) were employed to decipher the predictive value of cGAS-STING risk score and TIICs across several human cancers. …”
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1792
Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden
Published 2020-01-01“…Kaplan–Meier methods and Cox regression hazard proportional models were used. …”
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1793
Microscale total genomic DNA was used to explore the complete mitochondrial genomes of two biting midge species of the family Ceratopogonidae (Insecta: Diptera)
Published 2025-01-01“…In the key first step, the universal primers for cloning COX1 and 16S rRNA from insects are used, so the two-fragment cloning method may be widely used for insects.…”
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1794
Impact of non-participation bias due to psychiatric illness on mortality and cardiovascular event estimates: a Danish longitudinal population study
Published 2024-07-01“…Here, we investigate the mental health bias in a population study and the potential impact on estimates of cardiovascular morbidity and overall survival.Design Data were retrieved from nationwide registries.Setting The Danish General Suburban Population Study (GESUS), a cross-sectional community study conducted in Naestved Municipality, Denmark, from 2010 to 2013.Participants 49 707 subjects invited to participate in GESUS.Main outcome measures Factors related to non-participation were examined using multivariable logistic regression and time-to-event data using Cox proportional hazards models.Results Of 21 203 (43%) participants, 823 (3.9%) had a psychiatric diagnosis. …”
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1795
The prognostic importance of the pan-immune-inflammation value in patients with septic shock
Published 2024-01-01“…Median survival was longer in the low-PIV group than in the high-PIV group (28 (15.25 – 40.76) vs 16 (9.46 – 22.55) days, respectively, p < 0.05). The univariate Cox proportional hazards (CPH) model showed that high PIV (HR = 2.13 (1.03—4.38)), low GCS (HR = 3.31 (1.34 – 8.15)), high SOFA (HR = 9.41 (2.86 – 30.95)), high APACHE II (HR = 3.08 (1.47 – 6.45)), high lactate (HR = 6.56 (2.73 – 15.75)), and high procalcitonin (PCT) (HR = 2.73 (1.11 – 6.69)) values were associated with a decreased survival time among ICU patients (p < 0.05). …”
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The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank
Published 2025-01-01“…Participants were categorized into four groups according to the timing of their MVPA: “morning, evening, mixed, midday-afternoon”, with the midday-afternoon group serving as the reference. Cox proportional hazards models were utilized to evaluate the association between activity patterns and female reproductive diseases. …”
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1797
Activation of three targets by a TAL effector confers susceptibility to bacterial blight of cotton
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1798
Effect of healthy lifestyle score trajectory on all-cause mortality in the late middle-aged and older population: Finding from 17-year retrospective cohort study
Published 2025-02-01“…The chi-square test and Cox proportional hazards model were employed to examine the association between HLST and all-cause mortality over a 10-year follow-up period (December 31, 2012, to December 31, 2022; 3650 days). …”
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Medicaid Eligibility and Time to Re-incarceration Among Previously Incarcerated Subjects With Schizophrenia
Published 2016-10-01“…Time to Medicaid eligibility after release from incarceration, cumulative days of eligibility, and whether they were eligible on the re-incarceration date were evaluated in independent models. One and three-year Cox Regression models analyses (p<0.05) were used to evaluate the hazard for re-incarceration. …”
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Prediction of outcomes after chemoradiotherapy for cervical cancer by neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio
Published 2024-12-01“…The associations of PLR and other clinicopathological factors with 1-year survival rates were explored through univariate analysis and multivariate Cox regression analysis, respectively.Results NLR was significantly associated with the therapeutic effects of neoadjuvant therapy, with the optimal cut-off value of 2.89, area under the ROC curve (AUC) of 0.848 (95% confidence interval [CI]: 0.712–0.896), sensitivity of 0.892 (95% CI: 0.856–0.923) and specificity of 0.564 (95% CI: 0.512–0.592). …”
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