Incidence and predictors of respiratory tract infections among birth cohorts in Ethiopia, 2023 by Fekade Demeke Bayou, Mastewal Arefaynie, Anissa Mohammed, Abiyu Abadi Tareke, Awoke Keleb, Natnael Kebede, Yawkal Tsega, Bayu Hailemariam Mersha, Abel Endawkie, Shimels Derso Kebede, Kaleab Mesfin Abera, Eyob Tilahun Abeje, Ermias Bekele Enyew, Chala Daba, Lakew Asmare

“…A two-stage cluster sampling technique was used to select a total 2,246 eligible study participants from 206 enumeration areas. A Cox proportional hazards regression model was used to identify independent predictors of respiratory tract infection incidence. …”
Get full text

Prognostic factors and survival outcomes in patients with salivary duct carcinoma: a retrospective cohort study by Fei Chen, Liangbo Li, Jingqiao Tao, Nenghao Jin, Liwei Wang, Liang Zhu, Bo Qiao, Lejun Xing, Bo Wei, Jingqiu Bu, Haizhong Zhang

“…Univariate and multivariate Cox proportional hazards models were used to identify prognostic factors for overall survival (OS). …”
Get full text

Acute exacerbations in patients with progressive pulmonary fibrosis by Michael Kreuter, Elizabeth A. Belloli, Elisabeth Bendstrup, Stefania Cerri, Kevin R. Flaherty, Shane Shapera, Jin Woo Song, Heiko Mueller, Klaus B. Rohr, Yasuhiro Kondoh, on behalf of the INBUILD trial investigators, S. Quadrelli, M. Otaola, M.A. Bergna, P. Elias, G. Arce, A. Cazaux, J. Guiot, B. Bondue, C. Dahlqvist, L. Homik, S. Shapera, A. Cantin, M. Kolb, M. Salinas Fénero, R. Maturana Rozas, A. Silva Orellana, Z. Xu, Q. Luo, J. Kang, H. Cai, S. Marchand-Adam, E. Bergot, A. Gamez-Dubuis, F. Riviere, R. Kessler, H. Nunes, C. Marquette, L. Wemeau, S. Jouneau, F. Lebargy, B. Crestani, V. Cottin, M. Reynaud-Gaubert, S. Blaas, F. Bonella, W. Randerath, J. Hetzel, D. Koschel, M. Kreuter, A. Prasse, D. Skowasch, S. Stieglitz, R. Refini, S. Cerri, A. Pesci, S. Tomassetti, C. Vancheri, F. Varone, N. Sakamoto, S. Abe, H. Hayashi, T. Saito, T. Suda, H. Kitamura, M. Okamoto, Y. Kondoh, S. Makino, T. Takeuchi, Y. Yamada, C. Kono, Y. Inoue, H. Sugiura, K. Kishi, H. Takaya, H. Yamauchi, K. Ichikado, K. Tomii, H. Takahashi, S. Izumi, T. Kawamura, Y. Nishioka, Y. Miyazaki, J.W. Song, J.S. Park, Y. Kim, E. Jassem, J. Kus, W. Piotrowski, A. Barczyk, D. Ziora, E. Bazdyrev, S. Moiseev, S. Avdeev, M. Ilkovich, V. Yakusevich, C. Valenzuela, O. Acosta, M. Martínez, L. Gómez, M. Molina-Molina, D.M. Castillo Villegas, M. Aburto, J.A. Rodríguez Portal, A. Villar, A. León Jiménez, J. Sauleda, M. Arias, P. Beirne, H. Stone, B. Hope-Gill, N. Hirani, N. Chaudhuri, A. Gifford, L. Jones, L. Morrison, D. Antin-Ozerkis, N. Bhatt, T. Kulkarni, T. Moua, N. Ettinger, L. Pitts, S. Veeraraghavan, M. Padilla, E.R. Fernández Pérez, G. Giessel, M. Strek, S. Danoff, J. Burk, M. Rossman, N. Patel, E. Belloli, D. Hotchkin, S. Weigt, M.B. Scholand, R. Kaner, B. Sigal, Z. Safdar, L. Tolle, R. Martinez, M. Glassberg, R. Hallowell, J. Golden, M. Schwartz, E. Britt, L. Morrow, Y. Mageto, K. Buch, S. Chaaban, H. Poonyagariyagorn, D. Dilling, O. Shlobin, K. Thavarajah, A. Nambiar, I. Rosas, R. Bascom, J. Oldham, S. Schmidt, J. Dematte D'Amico, J. Falk, C. Glazer, G. Criner

“…Associations between baseline characteristics and time to first acute exacerbation were assessed using pooled data from both treatment groups using Cox proportional hazard models, firstly univariable models and then a multivariable model using forward stepwise selection. …”
Get full text

Surgery versus concurrent chemoradiotherapy for stage III non-small cell lung cancer: a retrospective study with propensity score matching by Takao Shigenobu, Yuri Taniguchi, Takahiro Suzuki, Yuya Tabuchi, Mizuki Sato, Kazumasa Odagiri, Yukiko Nakamura, Tsuneo Shimokawa, Hiroaki Okamoto, Akira Yoshizu

“…Propensity score matching was performed to balance baseline clinicopathological factors, and the prognoses of patients in each treatment group were examined using Cox proportional hazards regression. Results Of the 923 patients with NSCLC who underwent surgery, 97 with pathologic stage III NSCLC underwent complete resection (surgery group) and 125 with clinical stage III NSCLC underwent cCRT (cCRT group), of whom 54 (43.2%) received consolidation therapy with durvalumab. …”
Get full text

Exploring the association between pro-inflammatory diets and chronic liver diseases: evidence from the UK Biobank by Lili Pan, Lili Pan, Zhengrong Xu, Yining Li, Guoen Cai, Haibing Gao, Shenglong Lin

“…This study explores the relationship between the Dietary Inflammatory Index (DII), a measure of dietary inflammatory potential, and CLD risk.MethodsUtilizing data from the UK Biobank cohort, we assessed the dietary information and calculated the DII for each participant. Cox proportional hazards models and Fine-Gray competing risk models were employed to evaluate the association between DII and CLD incidence, adjusting for potential confounders.ResultsOur analysis included 121,329 participants with a median follow-up of 604.43 weeks, during which 4,018 developed CLD. …”
Get full text

Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study by Daniela Iacono, Serena Fasano, Ilenia Pantano, Virginia D’Abrosca, Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Luca Navarini, Nicola Maruotti, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini

“…The Kaplan–Meier curve and log-rank test were used to investigate differences in event-free survival. Cox regression analysis was carried out to identify factors associated with CV event occurrence. …”
Get full text

Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring by Ningyuan Wen, Dingzhong Peng, Xianze Xiong, Geng Liu, Guilin Nie, Yaoqun Wang, Jianrong Xu, Shaofeng Wang, Sishu Yang, Yuan Tian, Bei Li, Jiong Lu, Nansheng Cheng

“…These models, combined with other prognostic factors revealed by COX-PH model, enabled the establishment of nomograms for recurrence monitoring of CCA. …”
Get full text

Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…Real-world progression-free survival (rwPFS) and overall survival (rwOS) were evaluated among patients treated with SC or CRI using Kaplan-Meier and Cox proportional hazard methods. Baseline differences were balanced using propensity score-derived inverse probability treatment weights (IPTW). …”
Get full text

Prognostic impact of coronary microvascular dysfunction assessed by AMR in acute coronary syndrome patients with chronic kidney disease by Ziyu Guo, Yike Li, Qiang Chen, Jingang Zheng, Jingang Zheng

“…During a median follow-up of 23.0 months, higher prevalence rate of MACEs (28.3% vs. 15.1%, P = 0.003) and death (20.2% vs. 4.1%, P = 0.001) were observed in the CMD group. In multivariate Cox regression analysis, patients in the group of CMD had a 1.843 times higher hazard ratio (HR) for developing MACEs (HR: 1.843, 95% CI: 1.071–3.174, P = 0.027) and 5.325 times higher HR for developing death (HR: 5.325, 95% CI: 1.979–14.327, P < 0.001) for every 10 mmHg*s/m increment in AMR. …”
Get full text

A Novel Cancer Stemness-Related Signature for Predicting Prognosis in Patients with Colon Adenocarcinoma by Wei Wang, Congrong Xu, Yan Ren, Shiwei Wang, Chunli Liao, Xiaoyan Fu, Haixia Hu

“…Univariate and multivariate Cox regression analyses were applied to construct a prognostic risk cancer stemness-related signature. …”
Get full text

Long-term ambient air pollution and the risk of major mental disorder: A prospective cohort study by Chuyu Pan, Bolun Cheng, Shiqiang Cheng, Li Liu, Xuena Yang, Peilin Meng, Xin Qi, Na Zhang, Xiaoyue Qin, Dan He, Wenming Wei, Jingni Hui, Yan Wen, Yumeng Jia, Huan Liu, Feng Zhang

“…The association between air pollutants and incident MD was investigated by Cox proportional hazard model. Results During a median follow-up of 10.6 years, 9 004 participants developed MD. …”
Get full text

Increased risk of type 2 diabetes after traumatic amputation: a nationwide retrospective cohort study by Jung Eun Yoo, Jung Eun Yoo, Dagyeong Lee, Bongseong Kim, Won Hyuk Chang, Sang-Man Jin, Kyungdo Han, Dong Wook Shin, Dong Wook Shin

“…A total of 21,343 individuals with amputation during 2010–2018 and their 1:3 age- and sex-matched controls was included. We conducted Cox proportional hazard analysis to calculate the risk of T2DM among individuals with amputation.ResultsDuring the 4.2 ± 2.5 year mean follow-up period, there were 912 incident T2DM cases (10.7 per 1,000 person-years) among individuals with amputation. …”
Get full text

Association of frequent intradialytic hypotension with the clinical outcomes of patients on hemodialysis: a prospective cohort study by Yuanhao Wu, Jianda Lu, Tingting Wang, Xiaoye Zhu, Jun Xue, Li You

“…The Kaplan-Meier curves showed that frequent IDH patients had higher risks of all-cause mortality (p = 0.009, Definition 1; p = 0.002, Definition 2) and cardiovascular mortality (p = 0.021, Definition 1). Multivariable Cox regression analysis indicated that frequent IDH was independently associated with a higher risk of all-cause mortality (Model 1: HR = 2.553, 95%CI 1.334–4.886, p = 0.005; Model 2: HR = 2.406, 95%CI 1.253–4.621, p = 0.008). …”
Get full text

The correlation and predictive value of Hb, RDW and their association for short-term and long-term mortality in patients with acute aortic dissection by Peng Hou, Peng Hou, Lin Xia, Fangran Xin, Boxuan Sun, Guoxin Zhang, Liming Yu, Huishan Wang

“…BackgroundThis study examines the relationship between Hb, RDW and their association and both short-term and long-term mortality in patients with acute aortic dissection (AAD), aiming to establish combined effect between Hb and RDW as a potential prognostic biomarker for AAD outcomes.MethodsWe extracted clinical data from the Medical Information Mart for Intensive Care (MIMIC) databases for this analysis. Using adjusted Cox regression and Kaplan-Meier survival curve analyses, we assessed the relationship between Hb, RDW and their association at admission and mortality at multiple post-discharge intervals (30 days, 90 days, 1 year, and 5 years) among patients with AAD. …”
Get full text

Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study by Tong Liu, Wenqiang Li, Sarah Tan Siyin, Nan Yao, Ning Duan, Guoshuai Xu, Jun Qu, Siqing Liu

“…Epidemiological data, anthropometric parameters and biochemical data of participants were collected.Primary and secondary outcome measures Cox proportional hazards regression models were used to evaluate the association between hs-CRP concentrations and the risk of GSD after adjustments for potential confounders.Results During the mean 7.58 years of follow-up among 95 319 participants, 4205 participants were identified as newly diagnosed with GSD or having undergone cholecystectomy for cholelithiasis. …”
Get full text

Evaluation of the association between lymph node ratio and long-term survival in patients after surgery for lymph node-positive bladder cancer: a SEER population-based study with e... by Tao Chen, Xinchang Zou, Yihe Li, Lifen Peng, Zhen Song, Haichao Chao, Bin Fu, Tao Zeng

“…The Kaplan-Meier method and Cox regression model were utilized to evaluate the association between LNR and overall survival (OS) and cancer-specific survival (CSS). …”
Get full text

Adjuvant chemotherapy followed by concurrent chemoradiation is associated with improved survival for resected stage I‐II pancreatic cancer by Sung Jun Ma, Gregory M. Hermann, Kavitha M. Prezzano, Lucas M. Serra, Austin J. Iovoli, Anurag K. Singh

“…Kaplan‐Meier analysis, multivariable Cox proportional hazards method, forest plot, and propensity score matching were used. …”
Get full text

Preoperative carcinoembryonic antigen to lymphocyte ratio serves as a prognostic predictor in elderly patients with colorectal cancer: a multicentre retrospective study by Lei Jiang, Ning Tan, Xiaonan Zhang, Jiayi Jiang, Xinyi Li, Gang Deng, Tao Liang, Haohan Ma, Weiping Deng, Lichang Guan, Kaijun Zhang, Xujie Cai, Lishu Xu

“…Survival analyses revealed that CRC patients with CLR ≤2.53 tended to have better overall survival than those with CLR >2.53 (p<0.05 for all cohorts). Multivariate Cox proportional hazard models indicated that CLR ≤2.53 was significantly associated with reduced mortality risk in the derivation (HR: 0.405, p<0.001), external validation (HR: 0.519, p=0.039) and localised validation cohorts (HR: 0.167, p<0.001).Conclusions Preoperative CLR serves as a reliable predictor of all-cause death following curative resection in elderly patients with CRC. …”
Get full text

Changes in serum sodium concentration during hemodialysis is a predictor of mortality and cardio-cerebrovascular event by Qixing Liu, Ke Zheng, Haiyun Wang, Dan Song, Xuemei Li

“…Baseline pre-HD SNa and ΔSNa were collected; time-averaged pre-HD SNa and ΔSNa were computed as the mean values within 1-year, 2-year and 3-year intervals after enrollment. Cox proportional hazards models were used to evaluate the relationships of pre-HD and ΔSNa with outcomes.Results Time-averaged pre-HD SNa were associated with all-cause mortality (2-year pre-HD SNa: HR [95% CI] 0.86 [0.74–0.99], p = 0.042) and CCVE (3-year pre-HD SNa: HR [95% CI] 0.83 [0.72–0.96], p = 0.012) with full adjustment. …”
Get full text

The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer by Ross D. Dolan, Kathryn Pennel, Joshua Thompson, Molly McKenzie, Peter Alexander, Colin Richards, Douglas Black, Tanvir Abbass, Noori Maka, Josh McGovern, Antonia Roseweir, Stephen T. McSorley, Paul G. Horgan, Campbell Roxburgh, Donald C. McMillan, Joanne Edwards

“…Survival analysis was carried out using univariate and multivariate Cox regression. Results A total of 473 patients were included. …”
Get full text