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1481
Can Cryptogonimids of the Same Genus Influence Each Other’s Level of Genetic Variation?
Published 2024-12-01“…By using partial gene sequences of the mitochondrial <i>cox1</i> gene (715 bp), including 30 newly obtained sequences from the southern part of the Russian Far East, we found a low level of genetic variation in both species, consistent with previous findings of other trematodes from the same region. …”
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1482
Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma
Published 2025-01-01“…A prognostic model for UCEC was developed using LASSO Cox regression analysis and a Nomogram, integrating survival data, status, and gene signatures. …”
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1483
Donor Small-Droplet Macrovesicular Steatosis Affects Liver Transplant Outcome in HCV-Negative Recipients
Published 2019-01-01“…In negative recipients (n=122), graft loss was independently associated with graft Sd-MaS, in multivariable Cox regression models comprehending only pre-/intraoperative variables (HR=1.03, 95%CI=1.01-1.05; P=0.003) and when including indexes of early postoperative graft function (HR=1.04, 95%CI=1.02-1.06; P=0.001). …”
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1484
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis
Published 2024-05-01“…Our results show that OXH treatment reverses the changes in iNOS, COX-2, IL-1β, IL-6, and TNF-α levels. …”
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1485
The association between the dietary inflammatory index during pregnancy and risk of gestational diabetes: a prospective cohort study and a meta-analysis
Published 2025-02-01“…Each participant’s DII score was calculated, and then, the Cox proportional hazard model was used to calculate the hazard ratio (HR) and 95% CI of GDM across the quartiles of DII. …”
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1486
Correlation between hemoglobin, albumin, lymphocyte, and platelet score and short-term mortality in critically ill patients
Published 2025-02-01“…Additionally, the HALP score improved the predictive ability of the SOFA score (∆Area under curve: 0.009, p < 0.001). In Cox proportional hazards models, a low HALP score (HALP score < 3.2) was also associated with a higher risk of 28-day mortality (adjusted hazard ratio: 1.52, 95% CI: 1.33 to 1.74). …”
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1487
Tumor-Infiltrating Lymphocytes and Neutrophils and Their Location in Canine Mammary Neoplasms with a Solid Arrangement: A Prognostic Factor?
Published 2025-01-01“…This retrospective study assessed the density of peri- and intratumoral tumor-infiltrating lymphocytes (TILs), tumor-associated neutrophils (TANs), and CD3<sup>+</sup> and CD79<sup>+</sup> lymphocytes in canine mammary neoplasms with a solid arrangement, and associated such data with histological types, immunophenotype, prognostic factors, cyclooxygenase-2 (Cox-2) expression and overall and cancer-specific survival. …”
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1488
GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway
Published 2024-01-01“…A prognostic risk score model based on clinical phenotypic features was built using LASSO regression and step multi-Cox analyses. Gene set enrichment analysis (GSEA) was used to find potential molecular pathways associated with STAD. …”
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1489
A Nomogram for Predicting Overall Survival in Primary Central Nervous System Lymphoma: A Retrospective Study
Published 2025-02-01“…The least absolute shrinkage and selection operator (LASSO) regression and multivariate Cox regression analysis were used to identify the risk factors for overall survival (OS) and construct a nomogram. …”
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1490
广东省2009-2012年手足口病流行趋势分析
Published 2014-01-01“…男性高发,男女发病率之比(1.75 ~ 1.90)逐年下降;不同类型病例均主要集中于5岁以下儿童,以1~ < 2岁组儿童所占比例和发病率最高;EV71感染者的重症率(22.62% ~ 34.11%)和病死率(0.93%~3.83%)均比COX A16感染者(重症率:1.32%~ 3.48%;病死率:0.00%)要高。各年Moran’s I在0.39 ~ 0.51之间。…”
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1491
Associations of neutrophil/high-density lipoprotein cholesterol ratio with frailty and its mortality
Published 2025-01-01“…Weighted logistic regression, restricted cubic spline (RCS), and Cox regression were used to analyze the association of NHR with frailty and its long-term survival. …”
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1492
Delving into biomarkers and predictive modeling for CVD mortality: a 20-year cohort study
Published 2025-02-01“…The combined model, incorporating both biomarkers and demographic variables, demonstrated superior predictive performance with a C-index of 0.9205 (95% CI: 0.9129–0.9319), outperforming models with demographic variables alone (C-index: 0.9030 (95% CI: 0.8938–0.9147)) or biomarkers alone (C-index: 0.8659 (95% CI: 0.8519–0.8826)). Cox regression analysis further identified key predictors of CVD mortality, including elevated AST/ALT, TyG, BUN, and systolic blood pressure, with protective factors such as higher chloride and iron levels. …”
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1493
Kinetic-pharmacodynamic model to predict post-rituximab B-cell repletion as a predictor of relapse in pediatric idiopathic nephrotic syndrome
Published 2025-01-01“…This study aimed to identify factors that influence disease relapse and B-cell repletion to provide tailored treatment.MethodsLASSO and random survival forest were performed on 143 children to screen covariates which were then included in Cox regression model to determine the biomarkers of relapse and establish a nomogram. …”
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1494
Use of Minimal Residual Disease Status to Reduce Uncertainty in Estimating Long-term Survival Outcomes for Newly Diagnosed Multiple Myeloma Patients
Published 2023-01-01“…In the response-based PSM, survival was dependent on MRD status at the time of the response assessment via a landmark analysis. Cox-proportional hazard ratios from external sources and CASSIOPEIA informed the relationship for OS between MRD-positive and MRD-negative, and between patients receiving BTd and daratumumab plus BTd, respectively. …”
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1495
Survival outcomes of surgery and adjuvant chemotherapy in early-stage small cell and large cell lung cancer: a novel focus on tumors less than 1 cm
Published 2025-01-01“…The primary outcome was overall survival (OS) from diagnosis, which was evaluated using Kaplan–Meier methods and multivariate Cox regression analyses. A propensity score matching (PSM) analysis was performed to compare outcomes in patients with SCLC and tumors ≤ 1 cm who received adjuvant chemotherapy versus surgery alone. …”
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1496
Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma
Published 2022-01-01“…Kaplan-Meier survival analysis and Cox regression analysis suggested that downregulated FXYD2 could independently predict poor survival of ccRCC patients. …”
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1497
Lipid Metabolism-Related Gene Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Advanced Gastric Cancer
Published 2024-01-01“…We then used consensus cluster analysis to classify AGC patients into molecular subtypes based on lipid metabolism and constructed a diagnostic model using least absolute shrinkage and selection operator- (LASSO-) Cox regression analysis and Gene Set Enrichment Analysis (GSEA). …”
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1498
Peripheral Tumor Location Predicts a Favorable Prognosis in Patients with Resected Small Cell Lung Cancer
Published 2022-01-01“…Models of 2-year and 3-year survival were evaluated by deriving the area under receiver operating characteristic curves. Kaplan–Meier and Cox regression analyses were used to evaluate significant differences between the survival curves and hazard ratios. …”
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1499
Long noncoding RNAs predict the survival of patients with colorectal cancer as revealed by constructing an endogenous RNA network using bioinformation analysis
Published 2019-03-01“…Univariate and multivariate Cox's proportional hazard regression model revealed that five (H19, MIR31HG, HOTAIR, WT1‐AS, and LINC00488) out of 62 lncRNAs were closely related to the overall survival (OS) (P < 0.05). …”
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1500
Association between serum bicarbonate and 28-day mortality in critically ill patients with infective endocarditis: a cohort study from MIMIC-IV
Published 2025-01-01“…To evaluate the relationship between the serum bicarbonate and 28-day mortality, multivariable Cox regression was employed. The study included 450 patients with IE in serious condition in the ICU, with a 57.4-year-old average and 64.2% male representation. …”
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