Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer by Wei Tan, Fangfang Dai, Qinyu Ci, Zhimin Deng, Hua Liu, Yanxiang Cheng

“…Kaplan-Meier survival and Cox proportional hazards regression were used to identify prognostic genes for constructing risk models. …”
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Dying to be famous: retrospective cohort study of rock and pop star mortality and its association with adverse childhood experiences by Mark A Bellis, Karen Hughes, Olivia Sharples, Tom Hennell, Katherine A Hardcastle

“…An actuarial methodology compares postfame mortality to matched general populations. Cox survival and logistic regression techniques examine risk and protective factors for survival and links between adverse childhood experiences and cause of death, respectively.Setting North America and Europe.Participants 1489 rock and pop stars reaching fame between 1956 and 2006.Outcomes Stars’ postfame mortality relative to age-, sex- and ethnicity-matched populations (USA and UK); variations in survival with performer type, and in cause of mortality with exposure to adverse childhood experiences.Results Rock/pop star mortality increases relative to the general population with time since fame. …”
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Morphological change in an isolated population of red squirrels (Sciurus vulgaris) in Britain by Kim E. Chandler, Eloy Gálvez-López, Stuart Black, Andrew C. Kitchener, Kat Hamill, Bethan Roberts, Sean Doherty, Philip G. Cox

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Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E2 and F2α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Di... by Hisham Y. Al-Matubsi, Ghaleb A. Oriquat, Mahmoud Abu-Samak, Othman A. Al Hanbali, Maher D. Salim

“…On day 15 of gestation, the fetuses, placentas, and membranes were dissected, examined morphologically, and then homogenized, to measure cyclooxygenase (COX) activities and metabolisms of prostaglandin (PG) E2 (PGEM) and PGF2α (PGFM) levels. …”
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Evaluating short and long term outcomes following pediatric Myringoplasty with Gelfoam graft for tympanic membrane perforation following ventilation tube insertion by Jin Soo Song, Gerard Corsten, Liane B. Johnson

“…Overall mean time to closure was 5.6 (standard error (SE) 0.9) months. A multivariate Cox proportional hazards model demonstrated none of the covariates including graft material significantly affected TM closure. …”
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Determinants of Mortality among Adult HIV-Infected Patients on Antiretroviral Therapy in a Rural Hospital in Southeastern Nigeria: A 5-Year Cohort Study by Kelechi N. Eguzo, Adegboyega K. Lawal, Cynthia E. Eseigbe, Chisara C. Umezurike

“…Kaplan-Meier method was used to estimate survival and Cox proportional hazards models to identify multivariate predictors of mortality. …”
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Development and verification of prognostic nomogram for extraskeletal Ewing's sarcoma based on the SEER database by Feipeng Xiao, Weizhen Wang

“…After univariate or multifactor Cox regression analysis, the relevant variables were screened and a nomogram was constructed. …”
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Comprehensive analysis of telomere and aging-related signature for predicting prognosis and immunotherapy response in lung adenocarcinoma by Zhe Ye, Yiwei Huang, Tingting Chen, Youyi Wu

“…The prognostic model was constructed and evaluated using the least absolute shrinkage and selection operator (LASSO), multivariate Cox analysis, time-dependent receiver operating characteristic (ROC), and Kaplan-Meier (K-M) analysis. …”
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Zinc Deficiency and the Recurrence of Clostridium difficile Infection after Fecal Microbiota Transplant: A Retrospective Cohort Study by Blake A. Niccum, Daniel J. Stein, Brian W. Behm, R. Ann Hays

“…We controlled for risk factors for FMT failure using Cox regression. We also analyzed the effect of zinc supplementation in individuals with deficiency. …”
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Association between early ondansetron use and the risk of sepsis in intensive care unit patients: a secondary data of the Medical Information Mart for Intensive Care IV database by Xuan Liu, Qiuye Kou, Enhe Liu

“…According to the data from multivariate cox regression model, compared with participants without early ondansetron use, the risk of sepsis was reduced in participants with early ondansetron use relative to those without HR (HR=0.84, 95% CI: 0.76 to 0.93). …”
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Structural tailoring of etoricoxib: A spectrochemical, medicinal and pharmacological study by Bakul Akter, Silvia Aishee, Abdullah Hridoy, Md. Mehedi Hasan Pulok, Mohammad Ariful Islam, Antu Biswas, Aurna Patwary, Majedul Hoque, MD. Sazidul Islam, Md. Nipatul Hasan Nirob, Faisal Islam Chowdhury, Monir Uzzaman

“…Etoricoxib (ETC), a selective cyclooxygenase enzyme (COX-2) inhibitor, is widely utilized to manage pain and inflammation. …”
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Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia by Ding-Yun Feng, Yu-Qi Zhou, Xiao-Ling Zou, Mi Zhou, Hai-Ling Yang, Xiao-Xia Chen, Tian-Tuo Zhang

“…This reported mortality identified by the univariate Cox regression analysis is found to have been affected by the following factors: age greater than 70 years, presence of diabetes mellitus and chronic obstructive pulmonary disease, gastric tube intubation, administration of proton-pump inhibitor, blood albumin level less than 30 g/l, elevated neutrophil-to-lymphocyte ratio, antibiotics therapy in the preceding 90 days, intensive care unit (ICU) admission, blood lymphocyte count less than 0.8 × 109/L, elevated blood urea nitrogen/albumin (BUN/ALB) level, and presence of multidrug-resistant (MDR) pathogens. …”
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NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton by Van Thai Ha, Heung Soo Beak, Eunji Kim, Kwang-Soo Baek, Muhammad Jahangir Hossen, Woo Seok Yang, Yong Kim, Jun Ho Kim, Sungjae Yang, Jeong-Hwan Kim, Yung Hyup Joo, Chang Seok Lee, Joonho Choi, Hong-Ju Shin, Sungyoul Hong, Song Seok Shin, Jae Youl Cho

“…Furthermore, AP736 also downregulated the expression of multiple inflammatory genes, such as inducible NO synthase (iNOS), cyclooxygenase- (COX-) 2, and interleukin- (IL-) 1β in LPS-treated RAW264.7 cells. …”
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Outcomes of combined liver-lung transplant in pediatric patients with cystic fibrosis: An ISHLT transplant registry study by Renita Wilson, BS, J. Asher Jenkins, MD, Juan Maria Farina, MD, Blake Langlais, MS, Bashar Aqel, MD, Ashraf Omar, MD, Jonathan D’Cunha, MD PhD, Pedro Reck dos Santos, MD PhD

“…Data were propensity matched to LTx-only controls and analyzed with Fisher’s exact, Wilcoxon rank sum tests, Kaplan-Meier methods, and Cox proportional hazards where appropriate. Results: We identified 18 ConLi-LTx who were compared to 72 LTx-only cases. …”
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Association between frailty index and mortality in depressed patients: results from NHANES 2005–2018 by Xiaoqiang Liu, Yubin Wang, Yingxuan Huang, Chanchan Lin, Boming Xu, Yilin Zeng, Peizhong Chen, Xiaobo Liu, Yisen Huang

“…We recruited 2,669 participants with depression from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018 and quantified their frailty status using a 53-item frailty index. Cox proportional hazards models were used to estimate hazard ratios (HR) and their 95% confidence intervals (CI). …”
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Multifunctional Plumeria rubra nanoparticles: Antimicrobial, antiviral, antiparasitic and anti-inflammatory activities by Bassma H. Elwakil, Mohab H. Elsabrouty, Areej Eskandrani, Keshav Raj Paudel, Esraa Abdelhamid Moneer

“…Moreover, the synthesized Plumeria rubra nanoparticles' anti-inflammatory effect showed effective and selective COX-2 inhibition (IC50 = 4.2 μM, SI = 15.57). On top of that, the synthesized nanoparticles reduced the parasitic tachyzoites’ count by 37, 43, and 49 % in the spleen, brain, and liver, respectively.…”
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Effect of comorbidity classes on survival of patients with gastrointestinal tract cancer by Linna Gao, Tian Yao, Shaohua Ge, Jiuwei Cui, Wei Li, Zengqing Guo, Hongxia Xu, Min Weng, Suyi Li, Qinghua Yao, Wen Hu, Lan Zhou, Junqiang Chen, Xianghua Wu, Qingchuan Zhao, Hongli Li, Hanping Shi, Yi Ba, He Huang, The Investigation on Nutrition Status and its Clinical Outcome of Common Cancers (INSCOC) Group

“…Methods In a multicenter prospective observational study from 2012 to 2021, we grouped the comorbidities of patients with GTC by latent class analysis, obtaining two comorbidity classes. Cox regression models were initially used to predict mortality. …”
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The role of FAM171A2-GRN-NF-κB pathway in TBBPA induced oxidative stress and inflammatory response in mouse-derived hippocampal neuronal HT22 cells by Yi Wang, Jing Shan, Ling Zhang, Rui Wang, Meng-Yu Wu, Hong-Mei Li, Hai-Ming Xu

“…The results showed that TBBPA exposure could lead to an increase in the production of inflammation-related genes IL-6, iNOS, TGF-β1, COX2, and TNF-α in both HT22 cells and HT22-AD-model, intensifying the inflammatory response; it inhibits the mRNA expression of antioxidative enzymes genes Sod1, Cat, Gpx1, and Gsta1, resulting in reduced antioxidant enzyme activities of SOD, CAT, and GSH-Px/GPX. …”
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Rapid Improvement in Cardiac Damage Predicts Better Prognosis After Transcatheter Aortic Valve Replacement by Hao-Wei Lee, Chih-Hui Chin, Po-chin Chou, Chia-Hsiu Chang, Chiu-Ling Tsai, Chi-Hung Huang

“…During a median follow-up of 2.5 ± 1.9 years, 34.4% of patients met the primary endpoint, which included 16 deaths and 6 HF hospitalizations. Cox regression analysis revealed that improvement in cardiac damage correlated with a lower risk of composite death or HF hospitalization (HR: 0.095; 95% CI: 0.014–0.627; <i>p</i> = 0.015). …”
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The diagnostic and prognostic value of serum miR-199a-5p combined with echocardiography in acute myocardial infarction by Lixin Xu, Jianfeng Lin, Jianke Xia, Deng Chen, Guohan He

“…The occurrence of major adverse cardiovascular events (MACE) was recorded to analyze the prognostic value of miR-199a-5p by the Kaplan-Meier curve and Cox regression. Results Serum miR-199a-5p was elevated in AMI, positively correlated with cTnI and negatively correlated with LVEF. …”
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