Investigating the impact of persistent HPV infection on recurrence of lesions post-surgery for early-stage cervical cancer and related influencing factors by Jing Na, Ya Li, Qiao Lu, Yang Wang, Shichao Han, Jun Wang

“…ObjectiveTo explore the influencing factors of recurrence after surgical treatment for early-stage cervical cancer (stages IA1-IIA1) and to investigate the relationship between human papillomavirus (HPV) infection and postoperative recurrence of lesions.MethodsA retrospective analysis was conducted on the clinical data of 242 patients who underwent surgical treatment for early-stage cervical cancer (FIGO stages IA1-IIA1) at the Second Affiliated Hospital of Dalian Medical University between 2015 and 2022. Cox regression analysis was employed to evaluate the relationship between persistent postoperative HPV infection and lesion vaginal local recurrence while identifying the associated risk factors for persistent HPV infection following surgery.ResultsWithin 12 months postoperatively, the HPV clearance rate was 88.11%. …”
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Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer by Ke Zhu, Wen Deng, Hui Deng, Xiaoqiang Liu, Gongxian Wang, Bin Fu

“…The differentially expressed PPAR-targeted genes were investigated. Cox analysis and least absolute shrinkage and selection operator (LASSO) analysis were performed for screening prognostic PPAR-targeted genes and constructing the prognostic PPAR signature and then validated by GSE13507 cohort and GSE32894 cohort. …”
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肿瘤干细胞标志物CD133在非小细胞肺癌中的 表达及临床意义

“…CD133阳性表达率51.9%(40/77);CD133的表达与淋巴结转移呈正相关(r=0.246,P < 0.05),与患者手术后生存期呈负相关(P < 0.05)?COX多因素分析仅癌肿病理类型和CD133蛋白表达为影响生存率的独立因素? 【结论】 NSCLC的淋巴结转移和病理类型与预后有密切关系;肿瘤干细胞标志物CD133蛋白的表达与NSCLC的淋巴结转移和预后密切相关?…”
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Binge-like sucrose consumption reduces the dendritic length and complexity of principal neurons in the adolescent rat basolateral amygdala. by Masroor Shariff, Paul Klenowski, Michael Morgan, Omkar Patkar, Erica Mu, Mark Bellingham, Arnauld Belmer, Selena E Bartlett

“…Given the overlap in neural circuitry affected by drugs of abuse and sucrose, we sought to examine the effect of short- and long-term binge-like sucrose consumption on the morphology of the BLA principal neurons using an intermittent-access two-bottle choice paradigm. We used Golgi-Cox staining to impregnate principal neurons from the BLA of short- (4 week) and long-term (12 week) sucrose consuming adolescent rats and compared these to age-matched water controls. …”
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Survival analysis of conservative vs. dialysis treatment of elderly patients with CKD stage 5. by Roman Reindl-Schwaighofer, Alexander Kainz, Michael Kammer, Alexandra Dumfarth, Rainer Oberbauer

“…The risk of mortality was analyzed using multivariable Cox proportional hazards models. Furthermore, a parametric model of time to event analysis was used for visualization of changing risk over time and precise calculation of time to equal risk assuming a Weibull distribution. …”
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Landscape of Alternative Splicing Events Related to Prognosis and Immune Infiltration in Glioma: A Data Analysis and Basic Verification by Hong-xin Su, Gang Yang, Fei Su, Chen-xiao Hu, Tao Zhang, Jun-tao Ran, Quan-lin Guan

“…Altogether, 9028 AS events were discovered. Upon univariate Cox analysis, 425 AS events were found to be related to the survival of patients with glioma, and 42 AS events were further screened to construct the final prognostic model (area under the curve=0.974). …”
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Response to induction chemotherapy as a prognostic indicator in locally advanced head and neck squamous cell carcinoma by Francesca Huwyler, Roland Giger, Ruben Bill, Daniel Rauch, Simon Haefliger

“…Data were analyzed using Kaplan-Meier survival curves and Cox regression analysis. Results A total of 48 patients received IC. …”
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The kidney reabsorption-related magnesium depletion score is associated with cardiovascular disease and longitudinal mortality in diabetic kidney disease patients by Zhengxi Zhou, Xiaotian Yao

“…Weighted logistic regression analysis was used to explore the relationship between MDS and the occurrence of CVD. Weighted COX proportional hazards regression was used to explore the relationship between MDS and mortality. …”
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Analysis of Age Appropriate Measles Immunisation among the Eligible Children in India: A Cross-Sectional Analysis of National Family Health Survey–5 by Avijit Debnath, Niranjan Roy, Dipankar Roy, Munmi Sarma, Dipanjan Roy, Kinnor Das, Deepmala Deb

“…The sample comprised 48,928 children aged 12 to 23 months. Cox Proportional Hazard regression analysis was used to determine the significant influencing factors on age-appropriate measles immunization in India. …”
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Differences in risk factor profiles for peripheral artery disease compared to coronary, cerebral and carotid artery by Stefan Acosta, Yufeng Du, Yan Borné, Anders Gottsäter

“…The estimated population attributable risk fractions (PAF) for each atherosclerotic manifestation were estimated by first fit an age and sex adjusted Cox proportional hazard regression, and then estimate the PAF using the Direct method. …”
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Increase in assisted suicide in Switzerland: did the socioeconomic predictors change? Results from the Swiss National Cohort by Marcel Zwahlen, Nicole Steck, Christoph Junker

“…We calculated crude rates and used Cox proportional hazard and logistic regression models to examine associations of assisted dying with gender, marital status, education, religion, neighbourhood socioeconomic status and other variables, and investigated trends over time.Results We identified 3941 assisted suicides among 6 237 997 Swiss residents, 80% of which occurred in the older age group. …”
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A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer by Ruyue Chen, Zengwu Yao, Lixin Jiang, Jinchen Hu

“…We developed a GARRS using Cox-Lasso regression analysis, accurately stratifying patients into high- and low-risk groups. …”
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CTSK and PLAU as Prognostic Biomarker and Related to Immune Infiltration in Pancreatic Cancer: Evidence from Bioinformatics Analysis and qPCR by Yuntao Ding, Zhangzuo Li, Huizhi Wang, Qi Wang, Han Jiang, Zhengyue Yu, Min Xu

“…Prognostic values were assessed by the Kaplan-Meier and Cox regression analyses, and an overall survival (OS) nomogram was created to predict 1-, 2-, and 3-year survival after cancer diagnosis. …”
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Aurora-A在喉鳞癌中表达的临床意义 by 陈福进, 陈艳峰, 李秋梨, 田慎之

“…K- M 法计算分析 , Aurora- A 表达阳性者生存时间( 中位生存时间 46 月) 与Aurora- A 表达阴性者生存时间( 中位生存时间 85 月)有明显差异, P < 0.05。Cox 多因素回归分析显示切缘情况、肿瘤分化程度、临床分期及 Aurora- A 表达与喉鳞癌的预后有关, P 値均小于 0.05。…”
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The healthcare burden of isolated aortic valve insufficiency by Ibrahim Sultan, Michael Ryan, Candace Gunnarsson, Natalie Heidrich, Prashanth Vallabhajosyula

“…Outcomes of interest were all-cause mortality, time to home health, time to SNF, annualized healthcare utilization, and annualized costs. We used the Cox proportional model to estimate mortality and general linear models to estimate healthcare utilization and costs. …”
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Treatment Patterns for Patients on Overactive Bladder Therapy: A Retrospective Statistical Analysis Using Canadian Claims Data by Adrian Wagg, Demitri Diles, Todd Berner

“…Descriptive results were evaluated using univariate (Kaplan-Meier) and multivariate (Cox proportional hazards) models. **Results:** Data were available for 31,754 patients. …”
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Disparate Intent-to-Treat Outcomes for Pediatric Liver Transplantation Based on Indication by Anna Lang, Cameron Goff, Ashley Montgomery, Jake Lynn, Spoorthi Kamepalli, John Goss, Abbas Rana

“…Intent-to-treat survival analysis is important in this study because it is more comprehensive, combining the transplant outcomes of waitlist mortality, post-transplant mortality, and transplant rate into a single metric to elucidate any disparities in outcomes based on indication. Methods. Cox regression was used to analyze factors impacting survival in 8,002 children listed for liver transplant in the UNOS database between 2006 and 2016. …”
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Construction and Analysis of Hepatocellular Carcinoma Prognostic Model Based on Random Forest by Yikai Wang, Le Ma, Pengjun Xue, Bianni Qin, Ting Wang, Bo Li, Lina Wu, Liyan Zhao, Xiongtao Liu

“…The Kaplan‒Meier curve was used to evaluate its prognostic significance. Cox regression analysis was used to construct a survival prognosis prediction model, and the ROC curve was used to verify it. …”
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Impaired Mitophagy: A New Potential Mechanism of Human Chronic Atrial Fibrillation by Shuang Zhou, Weiran Dai, Guoqiang Zhong, Zhiyuan Jiang

“…The results of immunofluorescence staining and western blot showed an enhanced expression of Cox IV in the AF group. Dual immunofluorescent stainings revealed that mitophagy defect in atrial myocytes of patients with AF resulted from dysfunction in the process of delivery of mitochondria into autophagosomes. …”
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The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1 by Payal Khandelwal, Mythili K. Padala, John Cox, Ramareddy V. Guntaka

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