The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers by Y. Gidron, M. De Couck, D. Schallier, J. De Greve, J. L. Van Laethem, R. Maréchal

“…In PC patients, in a multivariate Cox regression controlling for confounders, the NIM index had a protective relative risk (RR) of 0.68 and 95% confidence interval (95% CI) of 0.51–0.92. …”
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Clinical features and prognostic factors of pediatric Langerhans cell histiocytosis: a single-center retrospective study by Yunfeng Lu, Liying Liu, Qi Wang, Bingju Liu, Ping Zhao, Guotao Guan, Yunpeng Dai

“…The 5-year OS and EFS rate in RO+ LCH and RO− LCH patients were 79.5 ± 7.5%, 53.8 ± 9.6% and 87.5 ± 11.7%, 76.2 ± 14.8%, insignificantly. Multivariate Cox regression showed that liver involvement predicted poor EFS and hematological system involvement was an independent prognostic factor for OS. …”
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儿童高危和超高危急性淋巴细胞白血病的预后因素分析

“…【结果】 总放弃治疗率25%，总预期6年无事生存率(EFS)49.3%，坚持治疗者EFS64.7%，非VHR-ALL组坚持治疗者EFS78.8%。Cox模型分析显示诱导33 d不缓解或BCR-ABL阳性是不良的独立预后因素，高强度化疗不能改变其预后差的特性，而泼泥松不敏感与其它任一项高危因素并存时复发法的危险性明显增高。…”
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Comprehensive Analysis of the Expression, Prognostic Value, and Immune Infiltration Activities of GABRD in Colon Adenocarcinoma by Fakun Huang, Zhengyang Wang, Liyue Zhu, Changqing Lin, Jia-xing Wang

“…GABRD expression was found to be an independent predictive predictor for overall survival, as determined by multivariate COX regression analysis. Additionally, the predictive nomogram model can accurately predict the fate of individuals with COAD. …”
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PWS/AS MS-MLPA Confirms Maternal Origin of 15q11.2 Microduplication by Angelika J. Dawson, Janice Cox, Karine Hovanes, Elizabeth Spriggs

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N-Acetylcysteine Decreases Myocardial Content of Inflammatory Mediators Preventing the Development of Inflammation State and Oxidative Stress in Rats Subjected to a High-Fat Diet by Klaudia Sztolsztener, Wiktor Bzdęga, Katarzyna Hodun, Adrian Chabowski

“…NAC administration ameliorated the COX-2 and 5-LOX expression, leading to a decrease in the PGE2 and LTC4 contents, respectively, and augmented the 12/15-LOX expression, increasing the LXA4 content. …”
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Analysis of Various Types of Glomerulonephritis with Crescents at a Single Center by Tomo Nakakita, Kenichi Akiyama, Kazunori Karasawa, Yoei Miyabe, Takahito Moriyama, Keiko Uchida, Kosaku Nitta

“…Factors affecting renal prognosis (end-stage renal failure requiring renal replacement therapy) were examined in a multivariate analysis using the Cox proportional hazards model. Kaplan–Meier curves and log-rank test were used to analyze and compare time from entry to renal death. …”
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The Efficacy of Processing Strategies on the Gastroprotective Potentiality of Chenopodium quinoa Seeds by Abdalbasit Adam Mariod, Suzy Munir Salama

“…All animals were sacrificed after an additional hour, and the stomach tissues were examined for histopathology of hematoxylin and eosin staining, immunohistochemistry of cyclooxygenase 2 (COX-2), and nitric oxide synthase (iNOS). Stomach homogenates were evaluated for oxidative stress parameters and prostaglandin E2 (PGE2). …”
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Nomogram for Predicting the Relationship between the Extent of Visceral Pleural Invasion and Survival in Non-Small-Cell Lung Cancer by Fan Wang, Pei Li, Fengsen Li

“…Clinical variables were calculated by means of multivariate Cox regressions and incorporated into the predictive model. …”
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Development and Validation of an Immunotherapy-Related Prognostic Signature Based on Lymph Node Ratio for Gastric Cancer by Jianxin Li, Ting Han, Xin Wang, Yinchun Wang, Xuan Chen, Wangsheng Chen, Qingqiang Yang

“…Then, we identified the differentially expressed genes (DEGs) related to LNR in the training cohort of GC. Univariate Cox regression and least absolute shrinkage and selection operator (LASSO) regression were performed to construct the risk score signature. …”
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Volume and distribution of white matter hyperintensities in rheumatoid arthritis and ulcerative colitis patients by Jennifer G. Cox, James H. Cole, Matthew J. Kempton, Steven C. R. Williams, Marius de Groot

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Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study by Ezhil Arasan Ramanan, Sailatha Ravi, K. R. Radha Anbu, Margaret Michael

“…Inositol and associated molecules display inhibitory properties against 5-α reductase, COX-2, and lipase enzymes in addition to their antimicrobial and anti-inflammatory properties. …”
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Evaluation of comorbidity burden on disease progression and mortality in patients with interstitial pneumonia with autoimmune features: A retrospective cohort study. by Elena K Joerns, Michelle A Ghebranious, Traci N Adams, Una E Makris

“…<h4>Methods</h4>In a retrospective study, we evaluated the prevalence and severity of comorbidities in an institutional cohort of patients with IPAF. Using Cox regression, we correlated the association of individual comorbidities and comorbidity indices with time to lung disease progression (relative forced vital capacity decline of 10% or more) and with time to lung transplant/death. …”
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Role of Traditional Cardiovascular Risk Factors after Initiation of Statin Therapy: A PharmLines Inception Cohort Study by Dennis Steenhuis, Stijn de Vos, Jens Bos, Eelko Hak

“…Using the unique linkage between biomedical data and prescription data from the PharmLines Initiative, we assessed the role of several risk factors used in cardiovascular risk models, using a time-dependent Cox PH model, in the occurrence of drug treatment of CVEs after initiation of statin therapy. …”
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HMGB2 Deficiency Mitigates Abdominal Aortic Aneurysm by Suppressing Ang-II-Caused Ferroptosis and Inflammation via NF-κβ Pathway by Hao Wu, Legao Chen, Kaiping Lu, Yi Liu, Weiqin Lu, Jinsong Jiang, Chao Weng

“…HMGB2 silencing considerably weakened Ang-II-caused VSMC ferroptosis, as revealed by the decrease of Fe2+ level and ACSL4 and COX2 levels and the increase in GPX4 and FTH1 levels. …”
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Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin by Michał Biernacki, Elżbieta Skrzydlewska

“…Phospholipids are subject to continuous transformation, including enzymatic hydrolysis (with the participation of phospholipases A, C, and D) to free polyunsaturated fatty acids (PUFAs), which under the influence of cyclooxygenases (COX1/2), lipoxygenases (LOXs), and cytochrome P450 (CYPs P450) are metabolized to various classes of oxylipins, depending on the type of PUFA being metabolized and the enzyme acting. …”
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Association of platelet-to-lymphocyte ratio with 1-year all-cause mortality in ICU patients with heart failure by Xinyu Hu, Shijiao Cheng, Huaan Du, Yuehui Yin

“…Patients were stratified into tertiles (0–126.45, 126.45–252.40, and 252.40–1000), and mortality risk was analyzed using Kaplan-Meier survival curves and Cox proportional hazards models. Elevated PLR was independently associated with higher mortality, with the highest tertile showing a 36% increased risk compared to the lowest (HR 1.36, 95% CI: 1.23–1.50, P < 0.001). …”
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A prognostic index model for predicting long-term recurrence of uterine leiomyoma after myomectomy. by Xiu Ming, Junying Zhou, Jinhai Gou, Na Li, Dan Nie, Luqi Xue, Zhengyu Li

“…A PI model was proposed based on the multivariate Cox regression analysis in the model group. The predictive value of this model was tested in both internal and external validation group.…”
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Environmental noise exposure and autoimmune diseases: Evidence from a national cohort study by Seunghyun Lee, Yongho Lee, Wanhyung Lee, Xiaoxue Ma

“…The HR were estimated using the Cox proportional hazards model, along with standardized incidence ratios (SIRs) for autoimmune diseases. …”
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Treatment of Sarcoptic Mange in Wombats With Topical Moxidectin by Hayley J. Stannard, Marie B. Wynan, Ray J. Wynan, Amanda Cox, Howard Ralph, Gregory S. Doran

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