Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth by Chu-Wen Li, Xiao-Li Wu, Xiao-Ning Zhao, Zu-Qing Su, Hai-Ming Chen, Xiu-Fen Wang, Xiao-Jun Zhang, Hui-Fang Zeng, Jian-Nan Chen, Yu-Cui Li, Zi-Ren Su

“…Preliminary mechanism studies demonstrated that ERP decreased the level of MPO and MDA, increased the activities of anti-oxidant enzymes (SOD, GPx, and GRd), attenuated the productions of TNF-α, IL-1β, IL-6, PGE2 and NO, and suppressed the activities of COX-2 and iNOS. This work demonstrates that ERP has considerable anti-inflammatory potential, which provided experimental evidences for the traditional application of the root and rhizome of Pogostemon cablin in inflammatory diseases.…”
Get full text

Combined detection of monocyte distribution width and procalcitonin for diagnosing and prognosing neonatal sepsis by Jiaping Wang, Ming Hu, Na Wang, Tingting Huang, Huiyi Wu, Hua Li

“…Relationships between variables were analyzed with Pearson correlation and Cox regression models; diagnostic performance was assessed using ROC curves. …”
Get full text

The Anti-Inflammatory, Phytoestrogenic, and Antioxidative Role of Labisia pumila in Prevention of Postmenopausal Osteoporosis by M. E. Nadia, A. S. Nazrun, M. Norazlina, N. M. Isa, M. Norliza, S. Ima Nirwana

“…LP contains antioxidant as well as exerting anti-inflammatory effect which can act as free radical scavenger, thus inhibiting TNF-α production and COX-2 expression which leads to decline in RANKL expression, resulting in reduction in osteoclast activity which consequently reduces bone loss. …”
Get full text

Application of the Bayesian Model Averaging in Analyzing Freeway Traffic Incident Clearance Time for Emergency Management by Yajie Zou, Bo Lin, Xiaoxue Yang, Lingtao Wu, Malik Muneeb Abid, Jinjun Tang

“…In addition, the BMA approach can provide better prediction performance than the Cox proportional hazards model and the accelerated failure time models. …”
Get full text

Peak Serum AST Is a Better Predictor of Acute Liver Graft Injury after Liver Transplantation When Adjusted for Donor/Recipient BSA Size Mismatch (ASTi) by Kyota Fukazawa, Seigo Nishida, Ernesto A. Pretto

“…The predictive value of ASTi of primary nonfunction (PNF) and graft survival was assessed by receiver operating characteristic curve, logistic regression, Kaplan-Meier survival, and Cox proportional hazard model. Results. Size-adjusted peak AST (ASTi) was significantly associated with subsequent occurrence of PNF and graft failure. …”
Get full text

An Interstitial 20q11.21 Microdeletion Causing Mild Intellectual Disability and Facial Dysmorphisms by Ivan Y. Iourov, Svetlana G. Vorsanova, Oxana S. Kurinnaia, Yuri B. Yurov

“…Array comparative genomic hybridization (CGH) has shown that the deletion resulted in the loss of 68 genes, among which 5 genes (COX4I2, MYLK2, ASXL1, DNMT3B, and SNTA1) are disease causing. …”
Get full text

Rationality of the FIGO2023 staging for early-stage endometrial cancer, compared with the FIGO2009 staging by Yiqin Wang, Jianliu Wang, Xingchen Li, Aoxuan Zhu, Yangyang Dong

“…Kaplan-Meier survival analysis was used to compare for prognostic differentiation. Cox regression was used to identify potential prognostic indicators.Results A total of 81 patients underwent staging shifts, all stage elevation. …”
Get full text

Effect of Raphia vinifera Fibre Size and Reinforcement Ratio on the Physical and Mechanical Properties of an Epoxy Matrix Composite: Micromechanical Modelling and Weibull Analysis by Syrille Brice Tchinwoussi Youbi, Omar Harzallah, Nicodème Rodrigue Sikame Tagne, Paul William Mejouyo Huisken, Tido Tiwa Stanislas, Jean-Yves Drean, Sophie Bistac, Ebenezer Njeugna

“…The distribution of strength and Young’s modulus follows Weibull’s law. Furthermore, the Cox–Krenkel mathematical model has the best approximated model for the experimental results after the tensile test. …”
Get full text

The Anti-Inflammatory Role of Vitamin E in Prevention of Osteoporosis by A. S. Nazrun, M. Norazlina, M. Norliza, S. Ima Nirwana

“…Vitamin E has also been shown to inhibit COX-2, the enzyme involved in inflammatory reactions. …”
Get full text

Prevalence and consequences of bovine subclinical mastitis in hill tract areas of the Chattogram division, Bangladesh by Md. Piplu Mia, Hemayet Hossain, Khadiza Akter Brishty, Md. Shahidur Rahman Chowdhury, Md. Imranuzzaman, Mostafizor Rahman, Sadia Islam Ria, Milon Mia, Md Saidul Haque, Md. Ashik-uz-zaman, Md. Nazmul Haque, Anzuman Ara, Md. Masudur Rahman, Md. Mahfujur Rahman

“…The prevalence of SCM at the farm level was 76.8% (43/56) in Chattogram and 69.5% (73/105) in Cox's Bazar. At the quarter level, the prevalence of SCM was found to be 32.29% (1307/4048; 95% CI: 30.9-33.8), while at the animal level, it was 41.3% (418/1012; 95% CI: 38.3-44.4). …”
Get full text

Comparison of the Development and Prognosis in Patients of Hypertriglyceridemic Pancreatitis with and without Diabetes by Wenjian Liao, Xiuxiu Niu, Wei Zhang, Xiaobing Liu

“…The clinical characteristics and prognosis data of these patients in the two groups were analyzed. Results. Multivariate Cox regression analysis showed that age, body mass index, glycated serum protein (GSP), and Acute Physiology and Chronic Health Evaluation (APACHE) II score were significantly associated with mortality in patients with HTGP. …”
Get full text

Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…NSAIDs, particularly selective cyclooxygenase-2 (COX-2) inhibitors, have shown potential as anticancer agents. …”
Get full text

Gaps in the ethical governance of pharmaceutical clinical trials in Europe by Rosemarie D. L. C. Bernabe, Rosemarie D. L. C. Bernabe, Shereen A. Dawkins-Cox, Christine C. Gispen-de Wied

Get full text

Evaluation of Vaso-occlusive Crises in United States Sickle Cell Disease Patients: A Retrospective Claims-based Study by Nirmish Shah, Menaka Bhor, Lin Xie, Steve Arcona, Rashid Halloway, Jincy Paulose, Huseyin Yuce

“…Clinical outcomes included mortality, inpatient pain crises, and complications. Cox regressions were applied to examine the relationship between pain crises and deaths or acute complications, respectively. …”
Get full text

The value of a metabolic and immune-related gene signature and adjuvant therapeutic response in pancreatic cancer by Danlei Ni, Jiayi Wu, Jingjing Pan, Yajing Liang, Zihui Xu, Zhiying Yan, Kequn Xu, Feifei Wei

“…A genetic prognostic model was developed via univariable Cox regression analysis on a training cohort. Predictive accuracy was assessed using Kaplan-Meier (K-M) curves, calibration plots, and ROC curves. …”
Get full text

Characteristics and Prognostic Nomogram for Primary Lung Lepidic Adenocarcinoma by Hui Tang, Caixia Qiao, Yingyi Wang, Chunmei Bai

“…Univariate and multivariate Cox proportional hazard models were performed to identify independent survival predictors for further nomogram development. …”
Get full text

Anti-inflammatory activity of Alpinia officinarum hance on rat colon inflammation and tissue damage in DSS induced acute and chronic colitis models by Vijayabharathi Rajendiran, Vidhya Natarajan, Sivasithamparam Niranjali Devaraj

“…In addition, the in-vitro study showed that HEAO treatment inhibited the proliferation of HT-29 cells and down regulated the mRNA expression of NF-κB and COX-2. Taken together, these results suggest that HEAO is a promising anti-oxidant and anti-inflammatory agent that support its possible therapeutic role in the treatment of colitis. …”
Get full text

The usefulness of Charlson Comorbidity Index (CCI) scoring in predicting all-cause mortality in Outpatients with Clinical Diagnoses of COPD by Kevin Ly, Dorothy Wakefield, Richard ZuWallack

“…Methods We tested the hypothesis that the Charlson Comorbidity Index (CCI) score at the time of an outpatient medical clinic encounter for COPD predicts all-cause mortality. Cox Proportional Hazards analyses were used in 200 randomly selected patients to relate CCI scores to all-cause mortality out to 5 years. …”
Get full text

Epichloë scottii sp. nov., a new endophyte isolated from Melica uniflora is the missing ancestor of Epichloë disjuncta by Torsten Thünen, Yvonne Becker, Murray P. Cox, Samad Ashrafi

Get full text

Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer by E. E. van Eeghen, M. J. Flens, M. M. R. Mulder, R. J. L. F. Loffeld

“…Primary outcomes were recurrence-free survival (RFS) measured through the Cox regression analysis and prevalence of EMVI. …”
Get full text