The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions by Wiktorowska-Owczarek Anna

“…Diclofenac belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and non-selective COX inhibitors. The aim of this study was to examine the effect of diclofenac on endothelial cell proliferation under the influence of hypoxia or inflammatory conditions. …”
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Research Advances in Antitumor Mechanism of Evodiamine by Luning Li, Cunxin Zhang, Chen Huang, Xinchen Tian, Wenxue Sun, Shulong Jiang

“…Evodiamine can inhibit Wnt/β-catenin, mTOR, NF-κB, PI3K/AKT, JAK-STAT, and other signaling pathways in various cancer cells, and it can significantly downregulate the expression of many tumor markers, such as VEGF and COX-2. These facts partially explain the antitumor mechanism of evodiamine. …”
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Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women: The Women's Health and Aging Study I by Kai Sun, Richard D. Semba, Linda P. Fried, Debra A. Schaumberg, Luigi Ferrucci, Ravi Varadhan

“…Women in the highest quartile of serum CML had increased risk of developing of severe walking disability in a multivariate Cox proportional hazards model, adjusting for age and other potential confounders. …”
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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

“…In addition, PD inhibited CLP-induced serum tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) production, lung cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase isoform (iNOS) protein expressions and NF-κB activation. …”
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Anti-Inflammatory Effect of By-Products from Haliotis discus hannai in RAW 264.7 Cells by Ho-Seok Rho, Hyang Kim, Jung-Ae Kim, Fatih Karadeniz, Byul-Nim Ahn, Ki-Ho Nam, Youngwan Seo, Chang-Suk Kong

“…Results indicated that presence of H. discus hannai mucosubstance by-products (AM) significantly lowered the nitric oxide (NO) production along the expressional suppression of inflammatory mediators such as cytokines TNF-α, IL-1β, and IL-6 and enzymes iNOS and COX-2. Also, AM was shown to increase expression of anti-inflammatory response mediator HO-1. …”
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Active Carbon Respiratory Masks as the Adsorbent of Toxic Gases in Ambient Air by Khayan Khayan, Taufik Anwar, Slamet Wardoyo, Widyana Lakshmi Puspita

“…Testing distinguishes the ability of cotton, spunbond, meltblown, and activated carbon as a respiratory mask to absorb toxic gases such as COx, NOx, and SOx. Test statistics are using the ANOVA test with a confidence level of 95%, α = 5%. …”
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Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease by Tsuneo Takenaka, Takahiko Sato, Hitoshi Hoshi, Nobutaka Kato, Keita Sueyoshi, Masahiro Tsuda, Yusuke Watanabe, Hiroshi Takane, Yoichi Ohno, Hiromichi Suzuki

“…Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. …”
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Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica) by Takuhiro Uto, De-Xing Hou, Osamu Morinaga, Yukihiro Shoyama

“…We previously reported that 6-MSITC strongly suppresses cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and cytokines, which are important factors that mediate inflammatory processes. …”
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Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer by Xiao He, Xianjie Cheng, Zhun Zhang, Lanhui Chen, Changjun Xie, Mengjie Tang

“…Our study seeks to create a predictive model for BRCA using efferocytosis-related genes (ERGs) to explore the significance of efferocytosis in this disease.MethodsIn this research, Differential analysis, and univariate Cox regression were employed to identify genes linked to prognosis in BRCA patients. …”
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Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study by Si Chen, Rui Nie, Xiaoran Shen, Yan Wang, Haixia Luan, Xiaoli Zeng, Yanhua Chen, Hui Yuan

“…Methods Clinical data from GCA patients were extracted from the MIMIC-IV (3.0) database. Logistic and Cox regression analyses, Kaplan–Meier (KM) survival analysis, restricted cubic spline (RCS) analysis, and mediation effect analysis were employed to investigate the association between age, RDW levels, and 180-day and 1-year mortality in GCA patients hospitalized or admitted to the ICU. …”
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Factors associated with retention and adherence on Pre-Exposure Prophylaxis among men who have sex with men in Kigali, Rwanda. by Sezi Mubezi, Samuel S Malamba, Gallican N Rwibasira, Jeanne Uwineza, Jean de Dieu Kayisinga, Eric Remera, Basile Ikuzo, Emah Ndengo, Nadege Umuhoza, Beata Sangwayire, Richard C N Mwesigwa, Caroline E Stamatakis, Manasseh G Wandera, Tom O Oluoch, Eugenie Kayirangwa

“…Retention was defined as attending scheduled PrEP follow-up appointments and adherence as taking PrEP medication 95% or more of the time. We used multivariable cox proportion hazard regression to determine factors associated with 3-month retention and principal component analysis (PCA) to determine factors associated with self-reported adherence. …”
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Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer by Ram Patel, John Mathews, Caroline Hamm, Swati Kulkarni, Rasna Gupta, Tarquin Opperman, John Dean Chiong, Abdullah Nasser

“…A Kaplan–Meier analysis was used to estimate the PFS and OS, and differences between the treatment groups were assessed using the log-rank test. Cox proportional hazards models were constructed to adjust for confounding factors. …”
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肺癌脊柱转移瘤的外科治疗疗效及预后因素分析 by 李玉希, 卢世新, 梁育玮, 李明, 程子颖, 黄浚燊, 黄家俊, 黄霖

“…单变量生存分析结果显示性别、吸烟史、病理类型、放化疗和靶向治疗对患者生存期有显著影响。多因素COX比例风险模型生存分析结果显示靶向治疗和放化疗是影响肺癌脊柱转移瘤患者预后的独立因素。结论外科手段治疗肺癌脊柱转移瘤能有效缓解患者的疼痛程度、提高生活质量和改善神经功能，靶向治疗和放化疗是影响肺癌脊柱转移瘤患者生存期的重要因素。…”
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Predictors and prognosis of elderly hip fracture patients with perioperative atrial fibrillation: a nested case–control study by Wei Li, Aoying Min, Wei Zhao, Weining Li, Shuhan Li, Saidi Ran, Mingming Fu, Qili Yu, Junkai Kou, Zhiqian Wang, Zhiyong Hou

“…An assessment of the correlation between baseline factors, complications, and all-cause mortality was conducted through univariable and multivariable Cox proportional hazards analysis. Results Enrolling 1,376 elderly patients with hip fractures, we found 1,189 in the non-AF group, 103 in the paroxysmal AF group, and 84 in the permanent AF group. …”
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Exploring and detecting predictors associated with survival and mortality of cervical cancer patients: a 10-year retrospective study by Shaba Muneeha, Raushan Kumar Chaudhary, Vijith Vittal Shetty, Soumya Patil, Uday Venkat Mateti

“…The data was analyzed using descriptive statistics, Kaplan–Meier curve, log-rank test and Cox regression. Results Out of 330 cervical cancer patients, majority (64.24%) were > 50 years of age followed by 35.76% were < 50 years. …”
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Diagnostic and Predictive Values of Inflammatory Factors in Pathology and Survival of Patients Undergoing Total Cystectomy by Xingxing Tang, Yudong Cao, Jia Liu, Shuo Wang, Yong Yang, Peng Du

“…The differences between different groups were analyzed by the Kaplan-Meier curves, and the predictive value of these IFs was determined by the Cox proportional hazards regression model. Results. …”
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Remnant cholesterol and its variability independent of low density lipoprotein cholesterol predict metabolic dysfunction associated steatotic liver disease by Yuting Sun, Xinlei Miao, Manling Hu, Xiaoling Xie, Shuang Liu, Ziping Song, Jiayi Deng, Fei Xu, Meng Li, Yangxuan He, Song Leng

“…A longitudinal cohort study involving 43,065 participants who underwent at least two physical examinations was conducted. This study used Cox proportional hazards models to assess the relationships among RC quartile levels (Q1–Q4), visit-to-visit variability, and the risk of MASLD. …”
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ApoB/ApoA-Ι is associated with major cardiovascular events and readmission risk of patients after percutaneous coronary intervention in one year by Jie Zhang, Mengyu Liu, Ju Gao, Xiaowen Tian, Yaru Song, Haibei Zhang, Peng Zhao

“…Univariate and multivariate Cox proportional hazards regression models were utilized to establish the relationship between ApoB/ApoA-I levels and MACEs/readmission. …”
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Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a prospect... by Zeyan Liu, Jinbo Wang, Yanfang Yang, Jinglin Cheng, Min Yang, Ye Zhang

“…The relationship between EAMI and MACE was analyzed using Kaplan–Meier curves, Cox regression, and restricted cubic spline (RCS) plots. …”
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Association between monocyte-lymphocyte ratio and all-cause and cardiovascular mortality in patients with chronic kidney diseases: A data analysis from national health and nutritio... by Wenwu Liu, Shuwei Weng, Chenghui Cao, Yuting Yi, Yue Wu, Daoquan Peng

“…The partial correlation analysis was conducted to assess the relationships between MLR and some important clinical features. Cox proportional hazards models were used to investigate the associations between MLR and mortality from all-cause and cardiovascular disease. …”
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