The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment by Yanchao Luan, Chao Liang, Qingsong Han, Xueqin Zhou, Na Yang, li Zhao

“…This was followed by the implementation of the univariate Cox and LASSO analyses in order to construct a LUAD gene signature. …”
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Synthesis of chitosan/PVA/copper oxide nanocomposite using Anacardium occidentale extract and evaluating its antioxidant, antibacterial, anti-inflammatory and cytotoxic activities by Manickam Rajkumar, S. I. Davis Presley, Prabha Govindaraj, Dharmalingam Kirubakaran, Farha Farahim, Talat Ali, Mohd Shkir, Sellapillai Latha

“…The CS/PVA/CuONCs exhibited excellent anti-inflammatory potency against COX-1 (67.10 ± 0.58%) and COX-2 (76.39 ± 0.65%). …”
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Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer by Ekamjit S. Deol, Reza Nabavizadeh, Roxane R. Lavoie, Mihai G. Dumbrava, Edlira Horjeti, Prabin Thapa, John C. Cheville, Igor Frank, Fabrice Lucien

“…Statistical analysis included Mann–Whitney U test, Fisher's exact test, Kaplan–Meier method, and Cox regression for survival analysis. Results Among 87 patients analysed, high B7‐H3 expression was found in 44.8% (n = 39) of patients. …”
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Complete mitochondrial genome sequence analysis revealed double matrilineal components in Indian Ghoongroo pigs by Pranab Jyoti Das, Satish Kumar, Manasee Choudhury, Seema Rani Pegu, K. Meera, Rajib Deb, Sunil Kumar, Santanu Banik, Vivek Kumar Gupta

“…Furthermore, examination of tRNA genes and nucleotide composition of different genes namely rRNAs, COX1, COX2, ATP6, ND4, ND5, ND6, Cytb offered insights into genetic diversity within these pigs. …”
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Exploring the association between socioeconomic inequalities in chronic respiratory disease and all-cause mortality in China: findings from the China Health and Retirement Longitud... by Zhuo Zhang, Guoshuai Shi, Faguang Jin, Yan Zhang

“…The concentration index was employed to measure socioeconomic-related inequality in CRD, and the concentration index decomposition method was used to describe its influencing factors. Cox proportional hazards regression model was employed to examine the association between CRD and all-cause mortality.ResultsThe prevalence of CRD was 11.79% (95% CI: 10.98, 12.66) in China. …”
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Baseline FIB‐4 May Be a Risk Factor of Recurrence After SBRT in Patients With HBV‐Related Small HCC by Zhan Zeng, Yifan Han, Wengang Li, Hongyu Chen, Ning Lin, Yanyan Yu, Xiaoyuan Xu

“…Risk factors were selected using Cox regression. The FIB‐4 was stratified for survival analysis. …”
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术前外周血中性/淋巴细胞比值对肝癌患者预后的影响

“…单因素分析显示术前AFP ≥ 400 g/L,肿瘤最大径>5 cm,肿瘤数目 > 3个,NLR≥5,血管侵犯及切缘阳性是影响肝部分切除术后肝癌无瘤生存及总生存时间的危险因素,Cox回归分析提示术前NLR ≥ 5,肿瘤数目>3个以及最大肿瘤直径 > 5 cm及切缘阳性是肝癌复发的独立危险因素(P < 0.01)。…”
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Prognostic Value of Endothelial Progenitor Cells in Acute Myocardial Infarction Patients by Gongjie Ye, Xiaodan Chen, Yinchao Zhou, Jianqing Zhou, Yongfei Song, Xiaoyong Yang, Lei Yang

“…CD34+/CD133+/KDR+ cells retained statistical significance in Cox regression models even after controlling for clinical variables (HR: 6.258 × 10−10 and P=0.001). …”
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A radiomics and deep learning nomogram developed and validated for predicting no-collapse survival in patients with osteonecrosis after multiple drilling by Fan Liu, De-bao Zhang, Shi-huan Cheng, Gui-shan Gu

“…Radiomics and deep learning features were extracted from pelvic radiographs and selected by LASSO-COX regression, radiomics and DL signature were then built. …”
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THE TURKISH-GERMAN AFFAIR IN FILMS: A DREAMWORLD OR A NETHERWORLD? by Ayça Tunç Cox

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A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli by Mallory Wright, Mandeep Kaur, Laura K. Thompson, Georgina Cox

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Determinants of Hospital Length of Stay among Patients with Pneumonia Admitted to a Large Canadian Hospital from 1991 to 2001 by Margaret J McGregor, J Mark FitzGerald, Robert J Reid, Adrian R Levy, Michael Schulzer, David Jung, Horacio E Groshaus, Michelle B Cox

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Current Perspectives in NSAID-Induced Gastropathy by Mau Sinha, Lovely Gautam, Prakash Kumar Shukla, Punit Kaur, Sujata Sharma, Tej P. Singh

“…Though several approaches for limiting these side effects have been adopted, like the use of COX-2 specific drugs, comedication of acid suppressants like proton pump inhibitors and prostaglandin analogs, these alternatives have limitations in terms of efficacy and side effects. …”
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Anti-Inflammatory and Anticoagulant Activities of Synthesized NSAID Prodrug Esters by Murad N. Abualhasan, Motasem Y. Al- Masri, Rufaida Manasara, Lana Yadak, Nael S. Abu-Hasan

“…The results showed an improved COX inhibition and anticoagulant activity compared with their parent drugs. …”
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Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

“…The association between duration of ART and liver damage (grade II–IV liver enzyme elevation [LEE] and/or total bilirubin elevation [TBE]), was analysed. Cox regression was used to examine the factors related to liver damage.Results Of 2119 eligible patients, 12.41% (263/2119) developed liver damage (grade II–IV LEE/TBE) and contributed 4.11/100 person-years crude incidence rate. …”
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The INFLUENCE 3.0 model: Updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy by M.C. Van Maaren, T.A. Hueting, D.J.P. van Uden, M. van Hezewijk, L. de Munck, M.A.M. Mureau, P.A. Seegers, Q.J.M. Voorham, M.K. Schmidt, G.S. Sonke, C.G.M. Groothuis-Oudshoorn, S. Siesling

“…Methods: Women, surgically treated for nonmetastatic breast cancer, diagnosed between 2012 and 2016, were selected from the Netherlands Cancer Registry. Cox regression with restricted cubic splines was compared to Random Survival Forest (RSF) to predict five-year LRR and CBC risks. …”
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Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer by Yasunobu Mano, Yasunobu Mano, Yuka Igarashi, Yuka Igarashi, Keisuke Komori, Keisuke Komori, Itaru Hashimoto, Itaru Hashimoto, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Hirohito Fujikawa, Takanobu Yamada, Hidetomo Himuro, Hidetomo Himuro, Taku Kouro, Taku Kouro, Feifei Wei, Feifei Wei, Kayoko Tsuji, Kayoko Tsuji, Shun Horaguchi, Shun Horaguchi, Shun Horaguchi, Mitsuru Komahashi, Mitsuru Komahashi, Mitsuru Komahashi, Takashi Oshima, Tetsuro Sasada, Tetsuro Sasada

“…In addition, the multivariate Cox proportional hazards model using these prognostic genes and clinicopathological information showed that combining the B cell marker CD19 and Ly had a high predictive accuracy for prognosis. …”
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Serum 25‐Hydroxyvitamin D Levels and Survival Outcomes in Advanced Biliary Tract Cancer: Results From the NIFTY Trial by So Heun Lee, Jaekyung Cheon, Ilhwan Kim, Kyu‐pyo Kim, Baek‐Yeol Ryoo, Jae Ho Jeong, Myoung Joo Kang, Byung Woog Kang, Hyewon Ryu, Ji Sung Lee, Changhoon Yoo

“…Baseline serum 25(OH)D levels were not associated with OS in either the multivariable Cox proportional hazard regression or restricted cubic spline analysis. …”
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Prognostic significance of neutrophil extracellular trap-related genes in childhood acute lymphoblastic leukemia: insights from multi-omics and in vitro experiment by Cheng Chen, Yu Ma, Yadai Gao, Huiqing Ge, Xiaochun Zhang

“…Prognostic genes were determined via multivariate Cox regression analysis, followed by the construction and validation of a risk model and nomogram. …”
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Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma by Dengfeng Lu, Fei Wang, Yayi Yang, Aojie Duan, Yubo Ren, Yun Feng, Haiying Teng, Zhouqing Chen, Xiaoou Sun, Zhong Wang

“…There were significant differences in clinicopathological characteristics and overall survival between groups. COX analysis suggested that CMRGS was an independent risk factor for glioma prognosis and had a better predictive performance than several classical indicators. …”
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