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481
Determination of the Effects of Camptothecin on Cell Cycling and Apoptosis in Human Leukaemic Cell Lines
Published 2001-01-01Get full text
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482
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483
Determinants of Policy Diffusion in Brazil and the U.S.
Published 2021-10-01“…It uses Weibull distribution and Cox regression to measure the time until events occur and to estimate the influence of a variety of factors on the likelihood of two policies being adopted. …”
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484
Necrotizing Pneumonia Complicated by Early and Late Pneumatoceles
Published 2008-01-01Get full text
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485
艾纳香油通过NF-κB非经典信号影响花生四烯酸代谢缓解LPS所致巨噬细胞的炎症反应
Published 2024-03-01“…结论BBO可能通过抑制NF-κB非经典信号中调节蛋白TRAF3和TRAF2,转录因子RelB的浓度,造成NIK蛋白的诱导激酶作用受到抑制,进一步抑制了p100蛋白的磷酸化及其与转录因子RelB的结合,从而影响到下游AA通路中重要限速酶<italic>COX-2</italic>、<italic>5-LOX</italic>和 <italic>FLAP</italic>的表达与炎症介质PGE<sub>2</sub>和LTB<sub>4</sub>的水平发挥抗炎作用。…”
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486
Prognostic value of intraductal carcinoma subtypes and postoperative radiotherapy for localized prostate cancer
Published 2025-01-01“…In addition, patients with IDC-P(+) pattern 2 were more likely to experience biochemical recurrence and death. Multivariate Cox regression analysis showed that pattern 2 was a risk factor for biochemical recurrence and death. …”
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487
<i>Endarachne binghamiae</i> Extract Ameliorates Inflammatory Responses in Macrophages Through Regulation of MAPK, NF-kB and PI3K/AKT Pathways, and Prevents Acute Lung Injury in Mi...
Published 2025-01-01“…In mRNA analysis, the expression of pro-inflammatory cytokines, COX-2, and iNOS mRNAs, was down-regulated by EB-WE treatment. …”
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488
Prognostic impact of tumor size on cancer-specific survival for postoperative WHO grade II oligodendroglioma: a SEER-based study
Published 2025-02-01“…Univariate and multivariate Cox analyses and Kaplan-Meier survival curves were used to identify and assess prognostic factors. …”
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489
Prognostic correlation analysis of multiple myeloma based on HALP score of peripheral blood before chemotherapy
Published 2025-01-01“…Univariate and multivariate analyses were conducted using the Cox regression model, and a forest plot was generated using Graphpad Prism to illustrate factors that may impact patient prognosis. …”
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490
Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-κB Pathway
Published 2018-01-01“…The results showed that the extract has significantly inhibited the production of the proinflammatory mediators including NO and PGE2; cytokines comprising IL-6, IL-1β, and TNFα; and enzymes covering the iNOS and COX-2 by preventing the IκBα from being degraded, to inhibit the nuclear translocation of NF-κB subunit p65 in order to hinder the inflammatory pathway activation. …”
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491
Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF
Published 2025-01-01“…A receiver operating characteristic (ROC) curve was used to explore the diagnostic value of BAR for 1-year all-cause mortality in IPF patients, and the survival rate was further estimated using the Kaplan–Meier survival curve. Cox proportional hazards regression model and forest plot were used to assess the association between the BAR and 1-year all-cause mortality in IPF patients.ResultsThe BAR of IPF patients was significantly higher in the non-survivor group than in the survivor group [0.16 (0.13–0.23) vs. 0.12 (0.09–0.17) mmol/g, p = 0.002]. …”
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492
Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study
Published 2025-02-01“…The secondary endpoint was in-hospital mortality and the rate of renal replacement therapy(RRT) use. Cox regression analysis and restricted cubic spline were used to analyze TyG index association with AKI risk. …”
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493
Identification of key chromium resistance genes in Cellulomonas using transcriptomics
Published 2025-02-01“…Cytochrome c subunits encoding genes qcrA and qcrC were involved in the intracellular reduction of Cr(VI), and cytochrome c oxidase subunits encoding genes coxB and coxC were involved in extracellular electron secretion. …”
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494
The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer
Published 2025-12-01“…The Kaplan–Meier survival curve and Cox proportional hazards model were used to assess the effect of DLEU1 on postoperative recurrence, metastasis and prognosis among patients with CC.Results Our research showed that DLEU1 expression in the serum exosomes of patients with CC was significantly upregulated compared to that in patients with cervical intraepithelial neoplasia (CIN) and healthy controls (HCs) (both p < .001). …”
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495
Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3
Published 2025-01-01“…Enzymatically oxygenated phospholipids (eoxPL) from lipoxygenases (LOX) or cyclooxygenase (COX) are prothrombotic. Their generation in arterial disease, and their modulation by cardiovascular therapies is unknown. …”
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496
Effect of Huaier granule on prognosis of breast cancer: A single-center propensity score matching retrospective study
Published 2025-01-01“…The disease-free survival (DFS) and overall survival (OS) for these groups were compared using the Kaplan–Meier method and the Cox regression. Results:. This study included 214 early invasive breast cancer patients, 107 in the Huaier group and 107 in the control group. …”
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497
Cannabidiol Alleviates Chronic Prostatitis and Chronic Pelvic Pain Syndrome via CB2 Receptor Activation and TRPV1 Desensitization
Published 2025-01-01“…Conclusions: CBD inhibits the TLR4/NF-κB pathway by activating the CB2 receptor, desensitizes the TRPV1 receptor, and decreases the release of COX2. This results in relief of inflammation and pain in patients with CP/CPPS, indicating CBD as a potential treatment for CP/CPPS.…”
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498
Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration
Published 2025-02-01“…Prognosis-related genes were screened and models were constructed using LASSO-Cox analysis. The models were validated by survival analysis. …”
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499
Association between triglyceride-glucose index and all-cause mortality in critically ill patients with acute myocardial infarction: analysis of the MIMIC-IV database
Published 2025-01-01“…Logistic regression and Cox proportional hazard analyses revealed that the TyG index was an independent predictor of in-hospital, 28-day, and 90-day mortality (OR: 1.406, 95% CI 1.141-1.731, p = 0.001; HR: 1.364, 95% CI 1.118-1.665, p = 0.002; HR: 1.221, 95% CI 1.024-1.445, p = 0.026, respectively). …”
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500
Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study
Published 2024-12-01“…Continuous Cox models demonstrated each 20 ml/min increase in eBFR linked to a 63% decrease in the risk of all-cause mortality (HR: 0.37, 95% CI: 0.23–0.59) and a 38% decrease in the occurrence of new MACE (HR: 0.62, 95% CI: 0.46–0.84). …”
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