丙烯醛体内外诱导神经元铁死亡的初步研究 by 彭伟嘉, 朱泽宇, 杨扬, 侯加卫, 皮荣标

“…同时丙烯醛可显著增加细胞内自由基与亚铁离子。此外，在细胞水平丙烯醛促进环氧化酶2（COX-2）、铁蛋白重链1（FTH1）表达上升，谷胱甘肽过氧化物酶4（GPX4）表达减少；在动物水平丙烯醛促进COX-2表达上升，GPX4、FTH1表达减少。…”
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Prognostic determinants and functional role of PIK3C2G in stage IIb-IIIa lung adenocarcinoma: insights from clinical and molecular analyses by Chao Gao, Jiaqi Zhang, Xin Du, Xuehan Gao, Xiayao Diao, Ke Zhao, Yeye Chen, Shanqing Li

“…Univariate and multivariate Cox regression analyses were conducted to identify prognostic factors. …”
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Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study by Hu H, Mu X, Zhao S, Yang M, Zhou H

“…The first part involved 555 patients with clinically diagnosed DKD, while the second part focused on 85 patients with biopsy-proven DKD. Cox regression analysis and competing risk regression were employed to identify independent predictors. …”
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Retrospective clinical analysis of time to recovery from diabetic ketoacidosis in Ethiopia by Angefa Ayele, Dube Jara, Alo Edin, Digafe Hailu, Mihiret Kifle, Yohannes Fekadu

“…Results from bivariable and multivariable Cox-regression were reported via adjusted hazard ratio with 95 % confidence intervals. …”
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Incidence and Risk Factors of Ventilator-Associated Pneumonia among Patients with Delirium in the Intensive Care Unit: A Prospective Observational Study by Morteza Shamsizadeh, Ali Fathi Jouzdani, Farshid Rahimi-Bashar

“…According to multivariate cox regression, the expected HR for VAP was 53.5% lower for patients with early-onset delirium than in patients with late-onset delirium (HR: 0.465, 95% CI: 0.241–0.894, P=0.022). …”
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Cardiovascular disease risk prediction by Framingham risk score in women with polycystic ovary syndrome by Mina Amiri, Maryam Mousavi, Mahsa Noroozzadeh, Fereidoun Azizi, Fahimeh Ramezani Tehrani

“…Among them, 215 women aged 30 years or older were diagnosed with PCOS. A Cox proportional hazards model applied to assess the relationship between the FRS and CVD event. …”
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Estimated Pulse Wave Velocity Is Associated With All‐Cause Mortality and Cardiovascular Mortality Among Adults With Chronic Kidney Disease by Xiao‐Hua Feng, Yi Chen, Xue‐Qi Chen, Wei‐Hong Zhao

“…Our study examined the association between ePWV and mortality risk based on weighted Kaplan–Meier plots and multivariate Cox regression. Linear testing between ePWV and mortality from all causes and CVD was performed using restricted cubic splines and Cox regression. …”
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Is Whole‐Brain Radiotherapy for Brain Metastases an Overestimated Therapy? A Retrospective Study of Real‐World Data Using Landmark Analyses by Florian Hoelzl, Oliver Koelbl, Isabella Gruber

“…The study analyzed prognostic factors for survival using Cox regression analyses, while two landmark analyses, reflecting a minimum survival of 60 and 90 days, accounted for early deaths. …”
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Factors associated with in-hospital mortality of newborns admitted to a special care newborn unit of a tertiary care hospital in southern Bangladesh: a retrospective cohort study by Md Mostafizur Rahman, Tahmina Zerin, Md Abdullah Saeed Khan, Md Golam Abbas, Aysha Haque, Mohammed Zahidul Alam, Ummay Thamima, Md Wahiduzzaman, Siddhartha Sankar Das

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The differential expression of AFF3 in cervical cancer and its correlation with clinicopathological features and prognosis by Yaxuan Zhang, Lanying Li, Qingling Han, Lanying Wen

“…The Univariate analysis of prognostic risk factors was conducted using the COX proportional hazards model, followed by multivariate COX regression analysis including variables with p < 0.01.Results AFF3 expression was downregulated in CC, and its levels were correlated with lymph node metastasis (LNM) and International Federation of Gynaecology and Obstetrics (FIGO) stage. …”
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Restoration effect of chemically modified microRNA-143-3p on acute myocardial infarction in animal models by Shingo Minatoguchi, Nobuhiko Sugito, Kazuki Heishima, Yuko Ito, Remi Nakashima, Hiroyuki Okura, Yukihiro Akao, Shinya Minatoguchi

“…In cultured rat H9c2 cells, miR143#12 significantly inhibited H2O2-induced autophagic cell death by decreasing ROS levels and increased viable cell numbers more than the control by silencing COX-1, -2, and ATG7. Replacement treatment with miR143#12 in the infarct areas, where the expression levels of miR143 were significantly decreased, has a beneficial effect on AMI by silencing COX-1 and -2.…”
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The additive effect of the stress hyperglycemia ratio on type 2 diabetes: a population-based cohort study by Cancan Cui, Jiayin Song, Lingyu Zhang, Ning Han, Wanqi Xu, Chen Sheng, Guangda Xin, Xiaofeng Cui, Lili Yu, Lin Liu

“…Participants were divided into SHR quartiles, and Cox proportional hazards regression and fine-gray competing risk models were used to assess SHR’s association with T2D onset, adjusting for fasting glucose and HbA1c. …”
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Clinicopathological characteristics and predictors of renal outcomes in diffuse crescentic glomerulonephritis : a retrospective single-center study from Western China by Shan Wen, Shasha Chen, Yingying Lin, Guisen Li, Ping Zhang, Wei Wang

“…Analytical methods included Cox regression models and Kaplan-Meier survival analysis to assess the data. …”
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Propensity score matched comparison of lymph node upstaging in early-stage lung cancer: open versus minimally invasive surgery with standardized lymphadenectomy by Julia Zimmermann, Julia Walter, Valentina Pfeiffer, Julia Kovács, Gökçe Yavuz, Johannes Schön, Mircea Gabriel Stoleriu, Christian Ketscher, Niels Reinmuth, Rudolf A. Hatz, Amanda Tufman, Christian P. Schneider

“…Frequency of categorical outcomes was compared with Chi [2]-test, mean values with t-test. We used logistic and Cox regression models to assess factors associated with upstaging, overall survival and progression-free survival, restrictively. …”
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The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study by Jinhua Zhu, Zeying Zhang, Yefei Lei, Zhenrong Ouyang, Shelby Kutty, Qiming Liu, Yunbin Xiao, Yunbin Xiao

“…The Kaplan–Meier survival curve was used to compare the cumulative survival rates of the high and low groups using the log-rank test. Multivariable Cox regression analyses were constructed to assess the relationship between AG and short-term outcomes in PH patients with sepsis.ResultsA total of 2,012 sepsis patients with PH were included. …”
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Association between dietary antioxidants, serum albumin/globulin ratio and quality of life in esophageal squamous cell carcinoma patients: a 7-year follow-up study by Juwei Zhang, Jinsong Zhou, Siting Chen, Yue Huang, Zheng Lin, Yuan Deng, Minglian Qiu, Zhisheng Xiang, Zhijian Hu, Zhijian Hu

“…The deterioration times were compared using the log-rank test, and the association of the combined DAI and AGR index with postoperative quality of life in ESCC patients was examined through Cox regression models.ResultsA total of 238 ESCC patients were included in the study. …”
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Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19: a multicenter, retrospective, cohort study by Haiyu Wang, Guangying Cui, Ming Cheng, Tuerganaili Aji, Guotao Li, Xinjun Hu, Guangming Li, Shixi Zhang, Yanyang Zhang, Linqi Diao, Pan Li, Ling Wang, Yiqiang Yuan, Guowu Qian, Ruiqing Zhang, Xiaoli Jin, Juan Wang, Hong Luo, Donghua Zhang, Mingming Wang, Silin Li, Zhan Song, Mengzhao Yang, Guanyue Su, Ranran Sun, Junbiao Chang, Zujiang Yu, Zhigang Ren

“…Clinical outcomes were compared between the two drugs via Kaplan–Meier analysis and Cox regression models. Additionally, in vitro and in vivo experiments were used to evaluate the antitumor effects and safety of both drugs. …”
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Machine learning model and nomogram to predict the risk of heart failure hospitalization in peritoneal dialysis patients by Liping Xu, Fang Cao, Lian Wang, Weihua Liu, Meizhu Gao, Li Zhang, Fuyuan Hong, Miao Lin

“…The prediction performance of ML methods and Cox regression was compared.Results Over a median follow-up of 49 months. …”
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Risk factors affecting long-term efficacy of ultrasound-guided high-intensity focused ultrasound treatment for multiple uterine fibroids by Zhenjiang Lin, Feng Xu, Yuan Yuan, Jiaojiao Peng, Jin Luo, Chunmei Gong, Dayong Chen, Yangyang Wang, Donghong Wang, Bing Yang, Lian Zhang

“…Recurrence, defined as PBAC score above or equal to 100 and/or the residual fibroid volume increased by 10%, was detected in 90 patients within 3 years after USgHIFU, with a cumulative recurrence rate of 20.2% (90/446). The multi-factor Cox analysis showed that age was a protective factor for recurrence. …”
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Establishing nomograms for predicting disease-free survival and overall survival in patients with breast cancer by Ling Zhou, Lifen Bai, Huiyin Zhu, Chongyong Guo, Sheng Liu, Lu Yin, Jian Sun

“…Univariate and multivariate Cox regression analyses were utilised to analyse the risk factors of recurrence and mortality. …”
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