SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study by Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum

“…Hazard ratios of subsequent symptomatic and severe infections were estimated using Cox regression with inverse probability weighting. …”
Get full text

Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…Stepwise regression, Harrell’s c-index, and clinician input were used to derive 2 multivariable Cox PH models from a set of candidate variables. …”
Get full text

慢性HBV 感染者血清HBsAg 自发转阴的影响因素分析 by 陈兴, 尤旭, 崇雨田, 李向永

“…【方法】选取中山大学附属第三医院974例未抗病毒的慢性HBV感染者为研究对象，定期收集患者临 床数据，包括人口学数据、基线及随访各时间点的生化学、病毒学、血清学、肝脾影像学指标，了解其血清HBsAg 自发转阴情况，并进行单因素和多因素COX回归分析。【结果】随访至2016年12月，974例慢性HBV感染者中共 54 例出现血清HBsAg 自发转阴，每年自发阴转率约为1.3%。…”
Get full text

Loss of p53 impairs death receptor expression and confers resistance to CD19 CAR T-cell therapy in BCP-ALL by Willem P. J. Cox, Noël M. M. Dautzenberg, Linde Dekker, Tesa Klenovsek, Annelisa M. Cornel, Marliek van Hoesel, Dorette S. van Ingen Schenau, Reno S. Bladergroen, Roland P. Kuiper, Laurens T. van der Meer, Friso G. Calkoen, Stefan Nierkens, Frank N. van Leeuwen

Get full text

Blood pressure control with active ultrafiltration measures and without antihypertensives is essential for survival in hemodiafiltration and hemodialysis programs for patients with... by Franklin Geovany Mora-Bravo, Pamela Tatiana Morales Torres, Nelson Rojas Campoverde, Guillermina Lucía Blum Carcelen, Juan Cristobal Santacruz Mancheno, Ángel Cristóbal Santacruz Tipanta, Hector Perez-Grovas, Willan Patricio Robles Abarca

“…The log-rank test (Mantel-Cox) was used for survival comparisons. Results The study included 106 patients. …”
Get full text

Postdiagnostic use of antihypertensive medications and survival in colorectal, lung, corpus uteri, melanoma and kidney cancer patients with hypertension by Rūta Everatt, Irena Kuzmickienė, Birutė Brasiūnienė, Ieva Vincerževskienė, Birutė Intaitė, Saulius Cicėnas, Ingrida Lisauskienė

“…Methods The association between 1-year postdiagnostic AH medication intake and the risk of death was examined in a population-based cohort of cancer patients including colorectal (N = 1104), lung (N = 344), melanoma (N = 334), corpus uteri (N = 832) and kidney cancer (N = 714), diagnosed between 2013 and 2015, and identified from the Lithuanian Cancer Registry. Multivariate Cox proportional hazards models were used to estimate hazard ratios (HRs), and corresponding 95% confidence intervals (95% CI) to assess associations between AH medications and cancer-specific and overall mortality. …”
Get full text

Systemic Predictors of Diabetic Retinopathy and Diabetic Macular Edema in an Adult Veteran Population by Tran EM, Gregori NZ, Rachitskaya A, Nandan A, Pershing S, Goldberg JL

“…After adjusting for sociodemographic factors, we used multivariable Cox regression models to evaluate the association of hemoglobin A1c (HbA1c) levels, blood pressure, albuminuria, blood urea nitrogen (BUN), and prescribed medications with the subsequent diagnosis of 1) any diabetic eye disease (defined for this analysis as DR and/or DME, 2) diabetic retinopathy, and 3) diabetic macular edema.Results: Of 4089 diabetic Veteran patients, 821 (20%) were subsequently diagnosed with diabetic retinopathy and 88 (2%) had macular edema. …”
Get full text

Knowledge discovery from database: MRI radiomic features to assess recurrence risk in high-grade meningiomas by Chen Chen, Lifang Hao, Bin Bai, Guijun Zhang

“…Combinations of data preprocessing methods, including normalization (Min-Max, Z-score, Mean), dimensionality reduction (Pearson Correlation Coefficients (PCC)), feature selector (max-Number, cluster) and ten-fold cross-validation were analyzed for their prediction performance. Kaplan–Meier curve, Cox proportional hazards regression model were used and concordance index (C-index), integrated Brier score (IBS) were selected. …”
Get full text

Association between frailty, as measured by the FRAIL scale, and 1-year mortality in older patients undergoing hip fracture surgery by Shaohua Xi, Zhibin Wu, Jian Cui, Suran Yin, Shaozhi Xi, Chaoyang Liu

“…Frail patients had a higher incidence of Clavien-Dindo (CD) classification of surgical complications ≥ II (31.3% vs. 12.3%, p = 0.00) and greater 1-year mortality (21.3% vs. 4.4%, p = 0.00) compared with non-frail patients. Cox regression analysis indicated that preoperative frailty was independently associated with 1-year mortality (adjusted hazard ratio: 3.88; 95% confidence interval [CI]: 1.28–11.77; p = 0.02). …”
Get full text

Oxidative Stress and Risk of Dementia in Older Patients with Depression: A Longitudinal Cohort Study Using Plasma Biomarkers by Yoo-Jin Jang, Min-Ji Kim, Su-Jin Lee, Shinn-Won Lim, Doh-Kwan Kim

“…AD conversion was determined using comprehensive neuropsychological assessment. Cox proportional hazards models were used to evaluate the association between oxidative stress biomarkers and AD conversion after adjusting for confounders. …”
Get full text

Long-term drought and risk of infant mortality in Africa: A cross-sectional study. by Pin Wang, Tormod Rogne, Joshua L Warren, Ernest O Asare, Robert A Akum, N'datchoh E Toure, Joseph S Ross, Kai Chen

“…The association between drought exposure and infant mortality risk was estimated using Cox regression models allowing time-dependent covariates. …”
Get full text

Mortality and Its Predictors among Adult Human Immune-Deficiency Virus-Infected Patients Attending Their Antiretroviral Treatment at Health Centers, Addis Ababa, Ethiopia: Multicen... by Selam Tesfayohannes, Sisay Shine, Abinet Mekuria, Sisay Moges

“…Regressions using the Kaplan‐Meier and Cox proportional hazards were employed. Results. …”
Get full text

Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease by Zhihao Qi, Quan Li, Shuhua Yang, Chun Fu, Burong Hu

“…<b>Results:</b> We identified seven DDR-related genes (<i>Arid5b</i>, <i>Cox5a</i>, <i>Erbb2</i>, <i>Ube2l3</i>, <i>Gpx1</i>, <i>H2bcl2</i>, and <i>Mapk3</i>), 33 DNA methylation genes, and two DDR-related proteins (CD274 and FCGR2A) which were all causally associated with IBD and its subtypes. …”
Get full text

Left Ventricular End-Systolic Volume Is a Reliable Predictor of New-Onset Heart Failure with Preserved Left Ventricular Ejection Fraction by Marina Kato, Shuichi Kitada, Yu Kawada, Kosuke Nakasuka, Shohei Kikuchi, Yoshihiro Seo, Nobuyuki Ohte

“…The prognostic value of LVESVI was investigated using a Cox proportional hazards model. Results. A univariable analysis demonstrated that age, log BNP level, tau, peak − dP/dt, LVEF, LV end-diastolic volume index (LVEDVI), and LVESVI were associated with adverse events. …”
Get full text

Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma by Lanhua Wu, Liang Li, Mingjing Zhu, Ziyan Zhou, Xuejin Su, Yueming Jiang, Min Kang, Li Jiang

“…Prognostic value was assessed using Kaplan–Meier curves, Cox regression analysis, and a nomogram. Drug sensitivity was predicted using the R package pRRophetic, and molecular interactions were analyzed using the DepMap database. …”
Get full text

Evaluación del rol del equipo de coordinación de nefrología en la consulta externa específica de acceso vascular. ¿Qué podemos aportar de nuevo? by Néstor Fontseré, Gaspar Mestres, Xavi Yugueros, Daniel Gil, Carla Blanco, Valentín Lozano, Lidia María Rodas, Arantxa Gelabert, Paula Escarcena, Rosa Ramos, Francisco Maduell

“…Se comparan las diferencias en las variables preoperatorias entre los grupos en los que las valoraciones entre ambos equipos fueron coincidentes y no coincidentes, la cirugía indicada y la permeabilidad primaria (PP) y secundaria (PS) durante el período de seguimiento (curvas de Kapplan-Meier y Log-rank test, y análisis de regresión de Cox). P significativa ≤ 0,05. Resultados: Se han analizado un total de 605 creaciones o reparaciones de AV: 74 ligaduras (12,2%), 207 FAVn distales (34,3%), 237 FAVn proximales (39,2%), 35 reparaciones (5,7%), 41 FAVp (6,7%) y 11 otros procedimientos (1,9%). …”
Get full text

Association of coronary revascularisation after physician-referred non-invasive diagnostic imaging tests with outcomes in patients with suspected coronary artery disease: a post ho... by Takao Kato, Moriaki Inoko, Naoya Matsumoto, Yukari Uemura, Masanao Naya, Mitsuru Momose, Satoshi Hida, Takao Yamauchi, Takatomo Nakajima, Eriko Suzuki, Tohru Shiga, Nagara Tamaki

“…The χ2 test, Student’s t-test, Kaplan-Meier analysis, log-rank test and multivariable Cox proportional hazard model were used in data analysis.Results A total of 210 (17.4%) patients in the SPECT stratum and 149 (23.8%) in the CT stratum underwent revascularisation. …”
Get full text

Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

“…Bivariable and multivariable analyses were conducted using Cox proportional hazard regression models to estimate hazard ratios (HR) of selected exposures and time to omphalitis. …”
Get full text

Association between the low-density lipoprotein to high-density lipoprotein ratio and prognosis in critically ill intracerebral hemorrhage patients: a retrospective cohort study fr... by Yuchen Liu, Houxin Fu, Yue Wang, Yi Zhong, Rongting Zhang, Jingxuan Sun, Tianquan Yang, Yong Han, Yongjun Xiang, Bin Yuan, Ruxuan Zhou, Min Chen, Hangzhou Wang

“…Initially, the association between LHR and short-term outcomes in ICH patients, including ICU mortality, in-hospital mortality, and 28-day mortality, was analyzed using Cox regression in both continuous and categorical models. …”
Get full text

Walking for transport and all-cause mortality: a prospective cohort study of Australian community-dwelling older adults by Rory Wolfe, Neville Owen, Ben Beck, Yang Chen, David W Dunstan, Alice Owen, Robyn L Woods, Danijela Gasevic, Joanne Ryan, Shivangi Shah, Carlene Britt

“…All-cause mortality was verified by two independent sources. Cox proportional-hazards models (HR and 95% CI) assessed the association between transport-related walking and all-cause mortality.Results Of participants, 44.1% reported walking every day, 31.5% more than once a week, 21.7% rarely or once a week and 2.7% never engaged in transport-related walking. …”
Get full text