Therapeutic Approaches in COVID-19 Patients: The Role of the Renin-Angiotensin System by Farzaneh Ketabchi, Sina Jamzad

“…However, the administration of COX inhibitors can reduce innate immune responses and have the opposite effect. …”
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Mechanism of Cytosolic Phospholipase A2 Activation in Ghrelin Protection of Salivary Gland Acinar Cells against Ethanol Cytotoxicity by Bronislaw L. Slomiany, Amalia Slomiany

“…The loss in countering effect of ghrelin occurred with cNOS inhibitor, L-NAME, as well as indomethacin and COX-1 inhibitor, SC-560, while COX-2 inhibitor, NS-398, and iNOS inhibitor, 1400W, had no effect. …”
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Markers of Inflammation and Fibrosis in the Orbital Fat/Connective Tissue of Patients with Graves’ Orbitopathy: Clinical Implications by Przemyslaw Pawlowski, Joanna Reszec, Anja Eckstein, Kristian Johnson, Andrzej Grzybowski, Lech Chyczewski, Janusz Mysliwiec

“…To assess FGF-β, TGF-β, and COX2 expression and immunocompetent cells in the orbital tissue of patients with severe and mild Graves’ orbitopathy. …”
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The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling by Zhenyu Zhang, Yina Gao, Yuanyuan Qian, Bowen Wei, Kexin Jiang, Zhiwei Sun, Feifan Zhang, Mingming Yang, Salem Baldi, Xiaoqi Yu, Yunfei Zuo, Shuangyi Ren

“…CUT‐Tag showed that Lyn/RUVBL1 silencing reduces the H3K27ac level in the COX2 promoter. Then, it is found that COX2 is regulated by the transcription factor FOXA1. …”
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Sildenafil (Viagra) Protective Effects on Neuroinflammation: The Role of iNOS/NO System in an Inflammatory Demyelination Model by Catarina Raposo, Ana Karolina de Santana Nunes, Rayana Leal de Almeida Luna, Shyrlene Meiry da Rocha Araújo, Maria Alice da Cruz-Höfling, Christina Alves Peixoto

“…We recently demonstrated that sildenafil reduces the expression of cytokines, COX-2, and GFAP in a demyelinating model induced in wild-type (WT) mice. …”
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Machine learning techniques for independent gait recovery prediction in acute anterior circulation ischemic stroke by Jiangping Ma, Yuanjie Xie

“…Predictive models were developed using the Random Survival Forest (RSF) and COX regression methods. The optimal model was identified based on C-index values. …”
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High pulse pressure is associated with an increased risk of prediabetes in hypertensive individuals: A retrospective study based on an adult Chinese population. by Zhanxing Wu, Zhongqing Chen, Wenfei Zeng, Ganggang Peng, Zhenhua Huang

“…A two-stage Cox proportional hazards regression model was used to determine the inflection point of PP in relation to the risk of prediabetes.…”
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Effects of Salmonella Typhimurium infection on intestinal flora and intestinal tissue arachidonic acid metabolism in Wenchang chickens by Shenghong Chen, Yaochen Xie, Dingqian Guo, Tiansen Li, Zhen Tan, Xuhua Ran, Xiaobo Wen

“…In HD11 cells, the use of a cyclooxygenase (COX) inhibitor reduced the increased levels of COX-2 and PGF2α induced by S. …”
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The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cyto... by Yuan-Yi Chia, Chien-Cheng Liu, Guan-Ming Feng, Chia-Chih Alex Tseng, Kuo-Chuan Hung, Chih-Chieh Chen, Ping-Heng Tan

“…LED therapy provides an analgesic effect and modifies the expression of COX-2, PGE2, and proinflammatory cytokines in incised skin.…”
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Only IF/TA in the Histological Evaluation of Post-Reperfusion Baseline Biopsies Correlates With Kidney Transplant Outcome by Quirin Bachmann, Carlos Torrez, Maike Büttner-Herold, Bernhard Haller, Flora Haberfellner, Renate Hausinger, Volker Assfalg, Lutz Renders, Kerstin Amann, Uwe Heemann, Christoph Schmaderer, Stephan Kemmner, Stephan Kemmner

“…Associations with delayed graft function (DGF) and death-censored graft survival were explored through Cox-regression analyses. The maximum follow-up time was 11.4 years, with DGF observed in 108 (32%) cases. …”
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Preference for and resistance to a toxic sulfur volatile opens up a unique niche in Drosophila busckii by Venkatesh Pal Mahadevan, Diego Galagovsky, Markus Knaden, Bill S. Hansson

“…This adaptability is likely linked to insensitivity of the enzyme complex cytochrome c oxidase (COX), which is a DMDS target in other insects. Our findings position D. busckii as a potential model for studying resistance to toxic gases affecting COX and offers insight into evolutionary adaptations within specific ecological contexts.…”
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The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer by Jie Zhu, Jiale Cheng, Yuyuan Ma, Ying Wang, Zhonghua Zou, Wenjie Wang, Haihua Shi, You Meng

“…Prognostic risk scores were calculated by univariate Cox regression analysis and Lasso-penalized Cox regression. …”
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Comprehensive analysis of ceRNA Networks in UCEC: Prognostic and therapeutic implications. by Li Fan, Mengqiu Lan, Xiaohua Wei, Lili Wei, Liuhong Yang, Liuying Nong, Jiajia Wei, Jingjing Li, Wenjie Huang

“…However, multivariate Cox regression suggested that other clinical factors may modulate this relationship. …”
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Evaluation of Overall Survival Predictions In Inoperable Pancreas Ductal Adenocarcinoma by Hasan Önner, Mustafa Erol, İlknur Küçükosmanoğlu

“…Univariate andmultivariate Cox regression analyzes were performed to investigate the variable affecting overall survival. …”
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Taenia asiatica: Mitochondrial signatures based analysis of an emerging public health threat in India by Aman D. Moudgil, Anil K. Nehra, Pallavi Moudgil

“…The sequences generated herein exhibited 99.60 % and 98.85 % similarity to the GenBank-archived sequences of T. asiatica corresponding to the nad1 and cox1 genes, respectively. Overall, 2 and 6 haplotypes for the overall data set with low nucleotide (0.00399 ± 0.00237 and 0.00095 ± 0.00042) and low haplotype (0.400 ± 0.237 and 0.131 ± 0.054) diversities were recorded for the nad1 and cox1 genes, respectively. …”
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Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma by Licheng Li, Ting Chen, Jishi Wang, Mengxing Li, Qinshan Li

“…Both multivariate and univariate Cox regression analyses were performed to identify autophagy-related genes. …”
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AI-assisted exposure-response data analysis: Quantifying heterogeneous causal effects of exposures on survival times by Louis Anthony Cox, Jr., R. Jeffrey Lewis, Saumitra V. Rege, Shubham Singh

“…The results add insights not easily obtained from traditional parametric or semi-parametric models such as logistic regression and Cox proportional hazards models, illustrating the advantages of non-parametric approaches for quantifying heterogeneous causal effects on survival times. …”
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Analysis methods for covariate-constrained cluster randomized trials with time-to-event outcomes by Amy M. Crisp, M. Elizabeth Halloran, Matt D. T. Hitchings, Ira M. Longini, Natalie E. Dean

“…We compared the performance of a semi-parametric Cox proportional hazards model with robust variance, a mixed effects Cox model, and a permutation test utilizing deviance residuals. …”
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Prediction of Postoperative Survival in Young Colorectal Cancer Patients: A Cohort Study Based on the SEER Database by Sheng Pan, Wenchao Mei, Linfei Huang, Yan’e Tao, Jing Xu, Yuelu Ruan

“…To assess the predictive ability of each predictor on the prognosis of colorectal cancer patients, we used two steps of Cox univariate analysis and Cox stepwise regression to screen variables, and the screened variables were included in a multifactorial Cox proportional risk regression model for modeling. …”
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Head Circumference for Growth Curves and Percentiles for 0-2-Year-Old Children in Ankara: Comparison with GAMLSS and Quantile Regression Methods by Eda Çakmak, Serhat Kılıç, Pınar Özdemir, Ergun Karaağaoğlu

“…Lambda-Mu-Sigma, LMSP, and LMST methods based on Box-Cox Cole and Green (BCCG), Box-Cox power exponential (BCPE), and Box-Cox t (BCT) distributions respectively, and quantile regression (QR) method were used to construct the fitted growth curves. …”
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