Compound heterozygosity of a De novo 16q24.1 deletion and missense mutation in COX4I1 leads to developmental regression, intellectual disability, and seizures by Zhen Liu, Mei He, Xuan Luo, Hu Pan, Xiao Mao, Jinping Su

Subjects: “…COX4I1…”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bovine blood cells during systemic immune challenge by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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Brief Communication: Histological Assessment of Nonhuman Primate Brown Adipose Tissue Highlights the Importance of Sympathetic Innervation by Abigail G. Williams, Masha Long, Kylie Kavanagh

“…Beta-3 adrenergic receptor abundance had a weak positive correlation with COX IV (p = 0.04) in BAT but did not significantly correlate to UCP1 or TH expression in BAT. …”
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Effect of Moringa Oleifera Leaf Extract on FGF21 mRNA Expression in Male Wistar Rats’ Skeletal Muscle Under Sedentary Condition by Titing Nurhayati, Karen Lolinhandary

“…The treatment group was administered 200 mg/kg of MO leaf extract, while the control group was given a standard diet and water for 12 weeks. COX IV and FGF21 mRNA levels in the soleus muscle were measured using real-time polymerase chain reaction. …”
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In Vitro Exposure to the Endocrine-Disrupting Chemical Climbazole Impairs Human Sperm Motility, Hormonal Signalling, and Mitochondrial Activity by Eugenia Annunzi, Francesca Paola Luongo, Francesca Girolamo, Rosetta Ponchia, Sofia Passaponti, Paola Piomboni, Alice Luddi

“…Gene expression of key components, including hormone receptors (<i>ESR1</i>, <i>ESR2</i>, <i>FSHR</i>, <i>AR</i>), apoptosis-related genes (<i>BAX</i>, <i>BCL2</i>), and <i>COX4l1</i> (involved in mitochondrial function), was analyzed. …”
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Effects of switching from stavudine to raltegravir on subcutaneous adipose tissue in HIV-infected patients with HIV/HAART-associated lipodystrophy syndrome (HALS). A clinical and m... by Pere Domingo, María del Mar Gutierrez, José Miguel Gallego-Escuredo, Ferran Torres, Gracia María Mateo, Joan Villarroya, Ignacio de los Santos, Joan Carles Domingo, Francesc Villarroya, Luis Del Rio, Vicente Estrada, Marta Giralt

“…Relative abundance of mtDNA, expression of PPAR gamma, adiponectin, Cyt b, and MCP-1 genes increased, whereas Cox IV, TNF alpha, and CD68 did not change significantly from baseline. …”
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The causal relationship between biological function of mitochondria and chronic kidney disease： a Mendelian randomization study by Yuan Xin-zhu, Li Ling-qin, Zhou Rui-jiao, Lin Chang-wei, Xia Meng-di, Wang Bao-fu, Xie Xi-sheng

“…The leave-one-out analysis results also confirmed the stability and reliability of the study findings.ConclusionThis study provides new evidence to elucidate the roles of NDUFB8， RRF， MRPL52， COX4i2， COX8A and DIABLO in the pathophysiology of CKD. …”
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The relationship of sphingolipid mechanisms with oxidative stress and changes in mitochondria during functional unloading of postural muscles by V. A. Protopopov, A. V. Sekunov, A. V. Panov, I. G. Bryndina

“…Unloading for 14 days was characterized by an increase in ASM, ceramide, ROS, NOX2, NOX4 and a decrease in COX IV and PGC-1α levels. ASM and ceramide were also increased in the mitochondrial fraction of muscle. …”
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Author Correction: Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

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Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset by Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou

“…Using single‐nucleus RNA sequencing data from an in vivo mouse model of sepsis, tissue‐independent down‐regulation and tissue‐specific differences of serine and energy‐related genes including key module roles for the mitochondria‐linked genes, Cox4i1, Cox8a, and Ndufa4 are identified. Finally, serine‐dependent metabolic shifts, especially in the liver, are revealed by using 12C/13C murine data with labeled serine, and link altered activity of the serine hydroxymethyltransferase (SHMT) cycle with perturbed purine metabolism during sepsis. …”
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A systematic review of digital and imaging technologies for measuring fatigue in immune mediated inflammatory diseases by Haley Mozier, Philip S. Murphy, Robert L. Janiczek, Mark Morris, Jennifer G. Cox, Hung Nguyen

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Local Ancestry and Adaptive Introgression in Xiangnan Cattle by Huixuan Yan, Jianbo Li, Kunyu Zhang, Hongfeng Duan, Ao Sun, Baizhong Zhang, Fuqiang Li, Ningbo Chen, Chuzhao Lei, Kangle Yi

“…By annotating the selection signals obtained by the CLR, <i>θ</i>π, <i>F</i>_ST, and XP-EHH methods, genes associated with immunity (<i>ITGB3</i>, <i>CD55</i>, <i>OTUD1</i>, and <i>PRLH</i>) and heat tolerance (<i>COX4I2</i>, <i>DNAJC18</i>, <i>DNAJC1</i>, <i>EIF2AK4</i>, and <i>ASIC2</i>) were identified. …”
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Transcriptomic Responses to Rapid Cold Hardening in Tomato Leafminer Adults: Implications for Tomato Leafminer Management by Yan Zhao, Farman Ullah, Jiayi Shi, Yingjie Hu, Yuyang Jiang, Youming Hou

“…Downregulated genes were found to be involved in metabolism and oxidative phosphorylation, including <i>COX4</i>, <i>ATPase_I,</i> and <i>ATP-synt_ab</i>. …”
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YAP K236 acetylation facilitates its nucleic export and deprived the protection against cardiac hypertrophy in mice by Panxia Wang, Luping Wang, Cui Liu, Yuehuai Hu, Guodong Feng, Zuqian Lian, Jing Lu, Ping He, Hexin Cai, Xiaohui Liang, Peiqing Liu, Xiaoqian Wu

“…Acetylation at K236 facilitated YAP’s nucleic export, suppressed the expression of target genes such as NRF1 and Cox IV, and counteracted YAP's anti-hypertrophic effects. …”
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Sportwissenschaft by Frese S, 2, Valdivieso P, Jaecker VC, Harms SA, Konou TM, Tappe KA, Schiffer T, Frese L, Bloch W, 6, Flück M, 7

“…Aerobic performanceand content per actin of markers of mitochondrial respiration (NDUFA9, SDHA, UQCRC1, COX4AI, ATP5A1, UCP3), myogenic regulators (myogenin, myoD, tenascin-C) and MyHC were determined in m. vastus lateralis of ten male elite junior cyclists (17.30.2 years) after the preparation and competition phase over two seasons. …”
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Macrophages and the microbiome in chronic obstructive pulmonary disease by Karanjot K. Sandhu, Aaron Scott, Amanda L. Tatler, Kylie B.R. Belchamber, Michael J. Cox

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Understanding scientific creativity: an exploratory creativity scale for organic chemistry by Connor Blue, Nathaniel Barr, Baldwin Ma, Helena He, Charles T. Cox, Paul Seli

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Dusting Hole Film Cooling Heat Transfer on a Transonic Turbine Blade Tip by Ward Manneschmidt, Hallie Collopy, Phillip Ligrani, Kyle Goethals, Matthew Cox, Hongzhou Xu, Michael Fox

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Gene Transcript Profiling in Desert Bighorn Sheep by Lizabeth Bowen, Kathleen Longshore, Peregrine Wolff, Robert Klinger, Michael Cox, Sarah Bullock, Shannon Waters, A. Keith Miles

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Longitudinal Analysis of Honey Bee Colony Health as a Function of Pesticide Exposure by Susan E. Kegley, Rosemarie Radford, Timothy J. Brown, Jeff Anderson, Darren Cox, Steve Ellis, Geoffrey W. Marcy

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