Challenges of sharing individual participant data for secondary research on neglected tropical diseases: the experience of Drugs for Neglected Diseases initiative and a call for ac... by Anastassia Negrouk, Thaddaeus Egondi, Craig Tipple, Justyna Tarwid, Michelle Childs, Dominique Junod-Moser

“…It also aims to advance the debate about best practice in the research community to avoid ‘IPD sharing paralysis’, with a focus on multistakeholder projects involving patients and researchers based in countries with various levels of data privacy regulations and measures.Results The article describes a practical case study outlining the ethical, legal and technical challenges encountered by DNDi in the context of IPD data sharing. …”
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Characteristics of Pediatric Crohn’s Disease in Saudi Children: A Multicenter National Study by Omar I. Saadah, Mohammad El Mouzan, Mohammad Al Mofarreh, Ali Al Mehaidib, Mohammad Al Edreesi, Mohammed Hasosah, Abdulrahman Al-Hussaini, Khalid AlSaleem

“…The aims of this study were to describe the characteristics of Saudi children with CD and to determine whether the characteristics of CD in KSA are different from those seen in Western countries. Methods. In this study, children younger than eighteen years of age diagnosed with CD between January 2003 and December 2012 were included. …”
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Immunologic investigations into transgene directed immune-mediated myositis following delandistrogene moxeparvovec gene therapy by Rachael A. Potter, Ida H. Moeller, Sohrab Khan, Hélène Haegel, Andreas Hollenstein, Guido Steiner, Christoph Wandel, Alexander P. Murphy, Damon R. Asher, Emanuel Palatinsky, Danielle A. Griffin, Stefanie Mason, Susan T. Iannaccone, Craig M. Zaidman, Louise R. Rodino-Klapac

“…It is approved in the US and in other select countries. Two serious adverse event cases of immune-mediated myositis (IMM) were reported in the phase Ib ENDEAVOR trial (NCT04626674). …”
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Phenotypic traits differentiating the genetic resources of pea (<i>Pisum sativum</i> L.) by the type of use by E. V. Semenova, A. P. Boyko, L. Y. Novikova, M. A. Vishnyakova

“…The object of the study was a sample of 494 pea accessions originated from 43 countries and 18 regions and territories of the Russian Federation. …”
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A Novel Sesterterpenoid, Petrosaspongin and γ-Lactone Sesterterpenoids with Leishmanicidal Activity from Okinawan Marine Invertebrates by Takahiro Jomori, Nanami Higa, Shogo Hokama, Trianda Ayuning Tyas, Natsuki Matsuura, Yudai Ueda, Ryo Kimura, Sei Arizono, Nicole Joy de Voogd, Yasuhiro Hayashi, Mina Yasumoto-Hirose, Junichi Tanaka, Kanami Mori-Yasumoto

“…The disease is endemic in 90 countries, and with millions of people at risk, it is seen as one of the ten most neglected tropical diseases. …”
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Association between NSAIDs and Clostridium difficile-Associated Diarrhea: A Systematic Review and Meta-Analysis by Nitipong Permpalung, Sikarin Upala, Anawin Sanguankeo, Suthanya Sornprom

“…Clostridium difficile infection is a leading cause of nosocomial diarrhea in developed countries. Studies evaluating the associations of increased risk of community-acquired CDAD and the use of nonsteroidal anti-inflammatory drugs (NSAIDs) have yielded inconclusive results. …”
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Burden and trends of dietary iron deficiency in the Middle East and North Africa region, 1990–2021 by Saeid Safiri, Saeid Safiri, Fatemeh Amiri, Nahid Karamzad, Nahid Karamzad, Mark J. M. Sullman, Mark J. M. Sullman, Ali-Asghar Kolahi, Morteza Abdollahi

“…The greatest reductions in prevalence were seen among older age groups, indicating an age-related downward trend from 1990 to 2021.ConclusionDespite some improvements, dietary iron deficiency remains a significant public health concern in the MENA region, particularly in countries with lower socio-demographic indices (SDI). …”
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Statistical Distribution of Urban Area Reveals a Converging Trend of Global Urban Land Expansion by Shengjie Hu, Zhenlei Yang, Sergio Andres Galindo Torres, Zipeng Wang, Haoying Han, Yoshihide Wada, Thomas Cherico Wanger, Ling Li

“…We analyzed the global urban extent data based on nighttime lights to examine the statistical distribution of urban land area at the global scale, and in 13 regions and countries over 29 years. The results reveal a converging temporal trend in urban land expansion from subnational to global scales, characterized by a coherent shift of urban area distribution from an initial power law toward an exponential distribution. …”
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CSO (Canadian Society of Otolaryngology - Head & Neck Surgery) position paper on rhinologic and skull base surgery during the COVID-19 pandemic by Yvonne Chan, Sarfaraz M. Banglawala, Christopher J. Chin, David W. J. Côté, Dustin Dalgorf, John R. de Almeida, Martin Desrosiers, Richard M. Gall, Artur Gevorgyan, A. Hassan Hassan, Arif Janjua, John M. Lee, Randy M. Leung, Bradford D. Mechor, Dominik Mertz, Eric Monteiro, Smriti Nayan, Brian Rotenberg, John Scott, Kristine A. Smith, Doron D. Sommer, Leigh Sowerby, Marc A. Tewfik, Andrew Thamboo, Allan Vescan, Ian J. Witterick

“…Abstract Healthcare services in many countries have been partially or completely disrupted by the Coronavirus (COVID-19) pandemic since its onset in the end of 2019. …”
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“Culture Is So Interspersed”: Child-Minders’ and Health Workers’ Perceptions of Childhood Obesity in South Africa by Roger Figueroa, Jaclyn Saltzman, Jessica Jarick Metcalfe, Angela Wiley

“…Child-minders and health workers play a crucial role in obesity prevention efforts, but their perceptions of childhood obesity in low- and middle-income countries are poorly understood. This study aims to (1) explore child-minders and health workers’ perceptions of the causes, consequences, potential strategies, and barriers for childhood obesity prevention and intervention in Cape Town, South Africa and (2) to provisionally test the fit of a socioecological framework to explain these perceptions. …”
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Optimizing the Future: A Game Theory to Tumor Therapeutic Strategies by Fang-Yuan Liu, Xin Liu, Dan-Ni Ding, Shao-Xuan Liu, Jing Xu, Yu-Xin Zhao, Yan-Hong Wang, Feng-Juan Han

“…Abstract Background Cancer poses significant economic and societal burdens on countries in the coming decades. During chemotherapy, patients frequently encounter adverse reactions. …”
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Climate Change Hotspots Identification in China through the CMIP5 Global Climate Model Ensemble by Huanghe Gu, Zhongbo Yu, Jigan Wang, Qin Ju, Chuanguo Yang, Chuanhao Fan

“…China is one of the countries vulnerable to adverse climate changes. The potential climate change hotspots in China throughout the 21st century are identified in this study by using a multimodel, multiscenario climate model ensemble that includes Phase Five of the Coupled Model Intercomparison Project (CMIP5) atmosphere-ocean general circulation models. …”
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Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Anci... by Oscar H. Del Brutto, Mark J. Sedler, Robertino M. Mera, Pablo R. Castillo, Elizabeth H. Cusick, Jadry A. Gruen, Kelsie J. Phelan, Victor J. Del Brutto, Mauricio Zambrano, David L. Brown

“…Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. …”
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Development of Entrepreneurial Activity Using the Integration of Human Capital and Green Technologies to Optimize the Sustainable Development of the Territories by Alma Karshalova, Aidos Akpanov, Santay Tleubayeva, Anuar Belgibayev, Askar Makhmudov, Aigul Atchabarova, Margarita Zholayeva

“…Meeting the requirements of the modern tourism industry is a problem not only for the Republic of Kazakhstan but also for other countries that strive for sustainable development of the tourism sector. …”
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Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings by J Cloete, M Karsas, T Chetty, A Pillay, M Archary, D Moore, T Reddy, Y Balakrishna, F Nakwa, R Lancaster, A Goga, P Jeena

“…In low-to-middle income countries (LMICs) like South Africa, research on antimicrobial usage for neonatal and paediatric healthcare-associated infections (HAI) is limited. …”
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Assessment of Microbiological Safety and Quality of Minced Meat and Meat Contact Surfaces in Selected Butcher Shops of Addis Ababa, Ethiopia by Kibrom Zerabruk, Negussie Retta, Diriba Muleta, Anteneh T. Tefera

“…Food-borne pathogens are one of the leading causes of illness and death particularly in developing countries. This study was aimed at analyzing the hygiene indicator microorganisms and pathogens of minced meat and contact surface materials in butcher shops in Addis Ababa, Ethiopia. …”
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Analysis of the Spatial and Temporal Differences of China’s Power Carbon Footprint by Zhen-Yu Zhao, Shu-Guang Yuan, Yu Fu, Ying Wang, Heng Li

“…Therefore, analyzing the regional ecological environmental carrying capacity of thermal power carbon emissions is of great significance for countries with high thermal power capacity to guide the development of low-carbon power and industrial layout. …”
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Bibliometrics of the current state of application of teletechnology in the rehabilitation of patients with heart and large blood vessel disease by Sican Wang, Ping Yu, Xuemei Zhou, Yuan Yuan, Jian Chen, Dongmei Chen, Jingyan Liang, Jingyan Liang, Li Xu

“…To bridge this gap, bibliometrics was used, a novel approach to determine the most prolific countries, institutions, journals, authors, source topics, funding agencies, and the most popular category of remote technologies and solutions for disease rehabilitation. …”
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The Study of Tariff Barriers and Foreign Exchange Rates Effects in the Function of Iran's Import Demand: A Critical Review of Iran's Trade Policy and Foreign Exchange Regime for Re... by Ali Zahedtalaban, Mahdi Khodaparast Mashhadi, Ahmad Sabahi, Mohamadreza Lotfalipour

“…So far, relatively a few studies have been conducted to investigate the effect of tariff rates on total imports of countries, which do not have consistent results. In this paper, we examine the actual effects of tariff and currency rates on the import demand function. …”
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Room temperature CRISPR diagnostics for low-resource settings by Eric A. Nalefski, Selma Sinan, Jason L. Cantera, Anastasia G. Kim, Remy M. Kooistra, Rafael E. Rivera, Jordyn P. Janshen, Sanchita Bhadra, Joshua D. Bishop, Andrew D. Ellington, Ilya J. Finklestein, Damian Madan

“…The reactions developed herein reduce the complexity and equipment requirements for affordable diagnostics in low- and middle-income countries.…”
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