Machine learning for predicting severe dengue in Puerto Rico by Zachary J. Madewell, Dania M. Rodriguez, Maile B. Thayer, Vanessa Rivera-Amill, Gabriela Paz-Bailey, Laura E. Adams, Joshua M. Wong

“…Feature importance analysis identified hemoconcentration (≥ 20% increase during illness or ≥ 20% above baseline for age and sex), leukopenia (white blood cell count < 4000/mm3), and timing of presentation at 4–6 days post-symptom onset as key predictors. …”
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An early lung cancer diagnosis model for non-smokers incorporating ct imaging analysis and circulating genetically abnormal cells (CACs) by Ran Ni, Yongjie Huang, Lei Wang, Hongjie Chen, Guorui Zhang, Yali Yu, Yinglan Kuang, Yuyan Tang, Xing Lu, Hong Liu

“…Furthermore, our results indicated that the model built using random forest (RF) method, which integrates clinical characteristics (age, extra-thoracic cancer history, gender), radiological characteristics of pulmonary nodules (nodule diameter, nodule count, upper lobe location, malignant sign at the nodule edge, subsolid status), the artificial intelligence analysis of LDCT data, and liquid biopsy achieved the best diagnostic performance in the independent external non-smokers validation cohort (sensitivity 92%, specificity 97%, area under the curve [AUC] = 0.99). …”
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General immunologic reactivity of patients with COVID-19 and its relation to gene polymorphism, severity of clinical course of the disease and combination with comorbidities by M.O. Sokolenko, L.P. Sydorchuk, L.S. Sokolenko, A.A. Sokolenko

“…The overall immunological reactivity was detected and evaluated based on the analysis of 14 integral leukocyte indices: leukocyte shift index, absolute leukocyte count/erythrocyte sedimentation rate (ESR) ratio index, lymphocyte-granulocyte index, lymphocyte index, immunological resistance and reactivity index, and others. …”
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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

“…Laboratory tests were performed to determine the levels of the following: (1) complete blood count; (2) nitrite + nitrate; (3) HbF; and (4) reticulocytes. …”
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Molecular, Cytogenetic, and Hematological Analysis of Chronic Myeloid Leukemia Patients and Discovery of Two Novel Translocations by Muhammad Asif, Abrar Hussain, Abdul Wali, Nazeer Ahmed, Irfan Ali, Zafar Iqbal, Muhammad Amir, Muhammad Shafiq, Mahmood Rasool

“…In this study, 131 CML patients were enrolled. Complete blood cell count was performed at the time of diagnosis for all the patients. …”
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Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods by Lisa M Gandy, Lana V Ivanitskaya, Leeza L Bacon, Rodina Bizri-Baryak

“…ObjectivePopular sentiment analysis tools based on natural language processing (NLP; VADER [Valence Aware Dictionary for Sentiment Reasoning], TEXT2DATA [T2D], and Linguistic Inquiry and Word Count [LIWC-22]), and a large language model (ChatGPT 4.0) were compared with manually coded sentiment scores, as applied to the analysis of YouTube comments on videos discussing the opioid epidemic. …”
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High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior by Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y

“…The expression of BMP7 in the bronchial epithelia of patients with COPD was negatively correlated with the airway counts measured by quantitative computed tomography, positively correlated with airway wall thickness, and negatively correlated with FEV1. …”
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Development and Validation of the Systemic Inflammatory Response Index-Based Nomogram for Predicting Short-Term Adverse Events in Patients With Acute Uncomplicated Type B Aortic In... by Wang Y, Wu X, Wang Y, Zhang Z, Liu X, Sun D, Liu X, Zhou T, Wang X

“…SIRI was calculated using neutrophil, monocyte, and lymphocyte counts. ARAEs were defined as death related to aortic disease, and the progression of IMH to aortic dissection or penetrating aortic ulcer. …”
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Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway by Xiaoying LIN, Aling SHEN, Meizhu WU, Ying CHENG, Xiaoping CHEN, Huixin LIU, Liya LIU, Zhiqing SHEN, Xiangyan WU, Nanhui XU, Jianfeng CHU, Youqin CHEN, Jun PENG

“…Western blot was used to detect the effect of BA on the protein expression of TGF-β and Smad2/3 in HCT116 cells after treated with BA for 48 h.Results:(1) CCK8 assay showed that the cell viability in each group was significantly reduced after treatment with different concentrations of BA for 24,48 and 72 h, and the differences were statistically significant compared with the 0 μmol/L group respectively (<italic>P</italic>&lt;0.05); The cell count results showed the number of cells in each group was remarkably decreased, and the differences were statistically significant compared with the 0 μmol/L group respectively (<italic>P</italic>&lt;0.05). (2) Transwell assay showed that the number of cells that migrated or invaded into the membrane was profoundly inhibited in each group after treatment with different concentrations of BA for 48 h, and the differences were statistically significant compared with the 0 μmol/L group respectively (<italic>P</italic>&lt;0.05). (3) Western blot assay showed that the protein expression of TGF-β and Smad2/3 was obviously decreased in each group after treated with different concentrations of BA for 48 h compared with the 0 μmol/L group.Conclusion:BA can inhibit the growth and metastasis of colon cancer cells, and its mechanism may be achived by regulating the TGF-β/Smad signaling pathway.…”
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Profil Sindrom Stevens Johnson pada Pasien Rawat Inap di RSUP Dr. M. Djamil Padang Periode Januari 2010 sampai Desember 2011 by Amelia Rahayu, Rina Gustia, Rahmatini .

“…The data were processed, counted the percentage, and presented in tabular form.The result showed there were 22 SJS cases (0,05%) with incidence ratio between male and female was 3:1. …”
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Inflammatory changes in the choroid plexus following subarachnoid hemorrhage: the role of innate immune receptors and inflammatory molecules by Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Martin Bareš, Alemeh Zamani, Parisa EmamiAref, Andrea Joukal, Lucie Kubíčková, Erik Kročka, Klaudia Hašanová, Marek Joukal

“…The number of CCR2 and CX3CR1 positive cells per choroid plexus area was manually counted. Immunohistochemical changes were confirmed by Western blot analyses.ResultsImmunohistochemical methods and Western blot showed increased levels of TLR9 and a slight increase in TLR4 and FRP2 following both subarachnoid hemorrhage as well as the application of artificial cerebrospinal fluid over time, although the individual periods were different. …”
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A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds by C. Persichilli, S. Biffani, G. Senczuk, M. Di Civita, M.K. Bitew, A. Bosco, L. Rinaldi, S. Grande, G. Cringoli, F. Pilla

“…To do this, faecal samples were collected from 642 Comisana and 323 Massese sheep over 3 years to assess Faecal Egg Counts, and Estimated Breeding Values (EBVs) for GIN resistance were estimated by a repeatability animal model. …”
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Peningkatan Akurasi Metode Weighted Fuzzy Time Series Forecasting Menggunakan Algoritma Evolusi Differensial dan Fuzzy C-Means by Agus Fachrur Rozy, Solimun Solimun, Ni Wayan Surya Wardhani

“…The Fuzzy C-Means classification resulted in finding 7 clusters with different membership counts. Forecasting values are calculated through defuzzification by converting linguistic variables into real numbers. …”
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Addition of Vitamin C on Diet to Improve Immunity on Tiger Grouper, Epinephelus fuscoguttatus to Infection Viral Nervous Necrosis by F. Johnny, K. Mahardika, I.N.A. Giri, D. Roza

“…Fish seed tiger grouper counted 400 fishes with wight between 35-55 disperse gram into 4 polycarbonate tanks volume of 1000 litres with density of 100 fish/tank.  …”
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SOIL TILLAGE VARIANTS AND SULPHUR FERTILIZATION AFFECT NODULATION, N2 FIXATION AND YIELD OF BAMBARA GROUNDNUT (Vigna subterreana) IN SOUTHEAST NIGERIA by M.A.N. Anikwe, Nnamnani D.E, Ikengannyia E.E, J.C. Eze, Obidike-Ugwu, E. O

“…At 30 DAP, the plots treated with till+gypsum1 (21 kg/ha), till+gypsum2 (42 kg/ha), no-till+gypsum2 (42 kg/ha), no-till+gypsum1 (21 kg/ha), and till+no gypsum had 62-63 % higher soil sulphur content (P= 0.05) than the control plots. The nodule count per plant in plots treated with no-till+gypsum2 (42 kg/ha) was greater than that in the control plot, plots with no-till+gypsum1 (21 kg/ha), and plots with till+gypsum2 (42 kg/ha) by 72-74 % at 30, 60, and 90 DAP across two seasons. …”
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Analysis of the correlation between the dose exposure intensity and apatinib in advanced gastric cancer: a retrospective cohort study by Xiao Ma, Xiao Ma, Lan Gao, Siying Che, Chaofeng Tao

“…The most common TRAEs of any grade were hypertension, proteinuria, and neutrophil count decreased. The incidence of grade 3-4 adverse reactions in the 500 mg cohort was higher than the 250 mg cohort (P=0.0016).ConclusionThe efficacy of apatinib in advanced gastric cancer was significantly positively correlated with dose exposure intensity, and HDEI can prolong PFS and OS. …”
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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

“…Multivariate analysis determined that the independent risk factors were age, race, norepinephrine, dopamine, phenylephrine, vasopressin, mechanical ventilation, intubation, hepatic failure (HepF), heart rate, respiratory rate, temperature, systolic blood pressure (SBP), anion gap (AG), blood urea nitrogen (BUN), creatinine, chloride, mean corpuscular volume (MCV), red blood cell distribution width (RDW) and white cell count (WCC). The C-index of the nomogram (0.767, 95% CI 0.759 to 0.779) was superior to that of the traditional Sequential Organ Failure Assessment, Acute Physiology Score III and Get With The Guidelines Heart Failure scores, indicating its discrimination power. …”
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Status and influencing factors of health literacy among college students of traditional Chinese medicine: a cross-sectional study by Jie Zhu, Cuixia Lin, Yanhui Yang, Rui Yao, Ran Yang, Mingqian Jiang

“…Descriptive statistical analysis was used to analyze the general data of the respondents, chi-square test was used to compare the count data between groups, and Logistic regression model was used to analyze the influencing factors of health literacy.ResultsThe health literacy level of TCM college students was 57.30%. …”
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Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study by Xiao Qin, Junming Ren, Chunping Xing, Lijiao Chen, Renjie Wang, Shouyuan Tian

“…Compared to the lower Hs-CRP group, patients in the higher Hs-CRP group exhibited higher age, heart rate, white blood cell count, blood urea nitrogen, creatinine, uric acid, fasting glucose, hemoglobin A1c, fibrinogen, D-dimer, and a higher prevalence of CKD, but lower hemoglobin, high-density lipoprotein cholesterol, albumin and estimated glomerular filtration rate. …”
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IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery by Cheng H, Ma J, Zhao F, Liu Y, Wu J, Wu T, Li H, Zhang B, Liu H, Fu J, He H, Zhu C, Ren H, Yang C, Qin S

“…The training cohort was analyzed utilizing X-tile software to identify the ideal threshold values for categorizing high-sensitivity C-reactive protein, albumin, lymphocyte count, and the CALLY index. The predictive significance of the IINS and CALLY index was evaluated through Kaplan–Meier survival curves and univariate and multivariate Cox regression analyses. …”
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