Single or multiple treatments with lusutrombopag in subjects with thrombocytopenia and chronic liver disease needing an invasive procedure by Davide Scalabrini, Paolo Sciuto, Cristina Felicani, Antonia Rudilosso, Pietro Andreone

“…This condition, when present in the severe form [platelet count (PLT) less than 50 × 109/L] correlates, with an increased risk of bleeding during the main diagnostic-therapeutic procedures which cirrhotic patients usually undergone. …”
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After Treatment Decrease of Bone Marrow Tregs and Outcome in Younger Patients with Newly Diagnosed Acute Myeloid Leukemia by Mario Delia, Paola Carluccio, Anna Mestice, Roberta Frappampina, Francesco Albano, Giorgina Specchia, Pellegrino Musto

“…However, although BMA Tregs did not differ in the study population after treatment, their counts significantly decreased in responder patients (p=0.039), while no difference was documented in nonresponder ones. …”
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Prognostic Role of Monocytic Myeloid-Derived Suppressor Cells in Advanced Non-Small-Cell Lung Cancer: Relation to Different Hematologic Indices by Asmaa M. Zahran, Helal F. Hetta, Zeinab Albadry M. Zahran, Alaa Rashad, Amal Rayan, Dalia O. Mohamed, Zeinab Ahmed Abd Elhameed, Salah M. Khallaf, Gaber El-Saber Batiha, Yasir Waheed, Khalid Muhammad, Hanaa Nafady-Hego

“…Furthermore, these cells accumulated significantly in stage IV compared to stage III (p=0.006) and correlated negatively with overall survival (r=−0.471, p=0.002), lymphocyte to monocyte ratio (r=−0.446, p=0.004), and mean platelet volume to platelet count ratio (MPV/PC) (r=−0.464, p=0.003), patients with Mo‐MDSCs<13% had significantly better survival than those with Mo‐MDSCs≥13% (p=0.041). …”
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Intramural pregnancy after intrauterine insemination in a nulligravid patient without previous uterine trauma, complicated by idiopathic thrombocytopenic purpura: A case report by Koyo Yamamoto, Tsuyoshi Takiuchi, Kengo Kiso, Saki Ishii, Satoshi Nakagawa, Yasuto Kinose, Michiko Kodama, Yutaka Ueda, Kenjiro Sawada, Takahiro Tsuboyama, Tadashi Kimura

“…Upon further investigation, the patient was diagnosed with idiopathic thrombocytopenic purpura, presenting with a platelet count of 30,000/μL. Due to the associated risk of hemorrhage, we proceeded with emergency exploratory laparoscopy after platelet transfusion. …”
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A Case of Undiagnosed HIV Infection in a 57-Year-Old Woman with Multiple Myeloma: Consequences on Chemotherapy Efficiency and Safety by I. Poizot-Martin, S. Brégigeon, C. Tamalet, R. Bouabdallah, O. Zaegel-Faucher, V. Obry-Roguet, A. Ivanova, C.E. Cano, C. Solas

“…Moreover, prophylactic medication is recommended in these patients regardless of CD4+ cell count at the initiation of chemotherapy.…”
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Effect of a Yogic Breathing Technique on Immune Parameters among Healthcare Workers: A Randomized Controlled Pilot Study by Archana Balasubramanian, Priyathersini Nagarajan, Mathangi Damal Chandrasekar, Kaviraja Udupa, Emmanuel Bhaskar, Divya Kanchibotla, Saumya Subramanian

“…A slight increase in interleukin (IL)-6 values and a higher IL-4 mean values was observed in the study group compared to controls. CD56 and CD8 counts were higher in the study group compared to controls. …”
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Memory B cells and their transcriptomic profiles associated with belimumab resistance in systemic lupus erythematosus in the maintenance phase by Takeshi Iwasaki, Takeshi Iwasaki, Hajime Yoshifuji, Koji Kitagori, Shuji Sumitomo, Shuji Akizuki, Ran Nakashima, Hideaki Tsuji, Ryosuke Hiwa, Mirei Shirakashi, Kosaku Murakami, Akira Onishi, Hideo Onizawa, Masao Tanaka, Fumihiko Matsuda, Akio Morinobu, Koichiro Ohmura, Koichiro Ohmura

“…Lower C4 and white blood cell counts may serve as clinical markers of higher memory B cells.…”
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Effect of Preoperative Nutritional Risk Screening on Postoperative Recovery in Patients with Laparoscopic-Assisted Radical Resection for Colorectal Cancer by Xiaolong Wang, Jianlin Wu, Sen Lei, Feng Tian, Ce Cao, Guangfeng Shi

“…There were statistically significant differences in BMI, albumin, total cholesterol, and lymphocyte count between patients from the two groups (all P<0.05). …”
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A Review of the Health Impact of Nicotine Pouches by Radosław Chmiel, Daria Michałka, Natalie Papachristoforou, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Natalia Tekiela, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan

“…Moreover, their use is linked to various health concerns such as cardiovascular issues, type 2 diabetes, oral mucosal changes, and decreased sperm count. Snus has been associated with a modest increase in cardiovascular disease risk, although the risks are lower than smoking. …”
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A new approach for hemodynamics of varicoceles: blood flow patterns based on contrast-enhanced ultrasound by Penglin Zou, Gaoxiang Fan, Zheng Li, Yuchen Tao, Chao Jia, Hongmei Liang, Ruhui Tian, Qiusheng Shi, Jianlin Hu, Rong Wu

“…The four patterns were further grouped into the “steady flow & intermittent stasis” and “intermittent reflux & filling defect” patterns for logistic regression analyses; the intermittent reflux & filling defect pattern was revealed as an independent risk factor for impaired sperm concentration, total sperm counts, progressive motility, morphology, and DNA fragmentation index. …”
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DRomics, a workflow to exploit dose-response omics data in ecotoxicology by Delignette-Muller, Marie Laure, Siberchicot, Aurélie, Larras, Floriane, Billoir, Elise

“…DRomics has been augmented especially to be able to handle varied omics data considering the nature of the measured signal (e.g. counts of reads in RNAseq) and the way data were collected (e.g. batch effect, situation with no experimental replicates). …”
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The Stress and Adversity Inventory for Adults (Adult STRAIN) in Korean: Initial Validation and Associations with Psychiatric Disorders by Eun Soo Kim, Yun Tae Kim, Kang-Seob Oh, Young Chul Shin, Sang-Won Jeon, Dong-Won Shin, Sung Joon Cho, George M. Slavich, Junhyung Kim

“…Finally, the test–retest reliability for total lifetime stressor count and severity over four weeks was high. Conclusions: The Korean STRAIN is a practical, valid, and reliable instrument for researchers and clinicians to efficiently assess lifetime stressor exposure.…”
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Comparative analysis of ChatGPT and Gemini (Bard) in medical inquiry: a scoping review by Fattah H. Fattah, Fattah H. Fattah, Abdulwahid M. Salih, Abdulwahid M. Salih, Ameer M. Salih, Ameer M. Salih, Saywan K. Asaad, Saywan K. Asaad, Abdullah K. Ghafour, Rawa Bapir, Rawa Bapir, Rawa Bapir, Berun A. Abdalla, Berun A. Abdalla, Snur Othman, Sasan M. Ahmed, Sasan M. Ahmed, Sabah Jalal Hasan, Yousif M. Mahmood, Fahmi H. Kakamad, Fahmi H. Kakamad, Fahmi H. Kakamad

“…The inclusion criteria consisted of studies that focused on using AI in medicine and assessed outcomes based on the accuracy and character count (length) of ChatGPT and Gemini. Data collected from the studies included the first author's name, the country where the study was conducted, the type of study design, publication year, sample size, medical speciality, and the accuracy and response length.ResultsThe initial search identified 64 papers, with 11 meeting the inclusion criteria, involving 1,177 samples. …”
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Fluoroscopic Stenting as a Bridge to Surgery versus Emergency Management for Malignant Obstruction of the Colon by Fan Xue, Feng Lin, Jun Zhou, Ning Feng, You-Gang Cui, Xu Zhang, Yu-Peng Yi, Wen-Zhi Liu

“…No significant differences between the two groups were observed in any of the clinicopathologic characteristics except for higher preoperative absolute neutrophil count in the ES group (P<0.001). Compared to the ES group, the SEMS group has significantly more cases, which featured a laparoscopic approach (72.7% vs. 14.0%, P<0.001), lower overall stoma rate (0% vs. 34.0%, P<0.001), and lower overall postoperative morbidity (27.3% vs. 56.0%, P=0.010). …”
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Toxicity test of compound essential oil nanoemulsion on fall armyworm (Spodoptera frugiperda J.E. Smith) eggs by Nurnina Nonci, Rita Noveriza, Araz Meilin, Melati Melati, Ifa Manzila, Arlyna B. Pustika, Haliatur Rahma, Erwin Najamuddin, Amran Muis

“…FAW egg masses were collected daily in the screen house and brought to the laboratory to count the number of eggs in one egg mass under a stereo microscope. …”
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Elevated Liver Function Tests as Predictors of Severe Maternal Outcomes in Women with Preeclampsia by Sadia Chaudhary, Hafiza Ateeqa Mubarak, Anila Sabir, Hina Sadaf, Anas Khalil, Zahid Mahmood, Marium Shoukat, Farah Naz Tahir

“… Background: Preeclampsia is a hypertensive disorder of pregnancy that ultimately led to high mortality and morbidity due to its complication HELP (Hemolysis, Elevated Liver Enzymes, and Low Platelet count), syndrome, and its association with elevated liver function tests. …”
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The Effect of Maternal Body Mass Index on in Vitro Fertilization-Intracytoplasmic Sperm Injection Treatment: A Prospective Comparative Study by Zeynep Ozturk Inal, Hasan Ali Inal

“…Results: While there were no differences between the groups in terms of age, smoking status, etiology of infertility, thyroid-stimulating hormone, prolactin levels, antral follicle count, and stimulation protocol (p>0.05), there was a significant statistical difference in terms of body mass index, duration of infertility, baseline follicle-stimulating hormone, luteinizing hormone, estradiol (E2), duration of stimulation, total gonadotropin dose required, peak E2 levels, progesterone levels, endometrial thickness on hCG administration, and cycle cancellation rate (p<0.05). …”
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Gut microbial alteration in chronic spontaneous urticaria unresponsive to second generation antihistamines and its correlation with disease characteristics‐ a cross‐sectional case‐... by Indrashis Podder, David Pesqué, Nerea Carrón, Pedro Iñaki González Torres, Ramon M. Pujol, Ana M. Giménez‐Arnau

“…Among CSU patients, higher Bacteroides and reduced Firmicutes count were associated with higher disease activity and poor control; however, there was no link with the type of therapy. …”
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Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma. by Anton W Roodnat, Chelsey Doyle, Breedge Callaghan, Karen Lester, Megan Henry, Carl Sheridan, Declan J McKenna, Colin E Willoughby, Sarah D Atkinson

“…For both mRNA and miRNA species, differential expression was determined using a bioinformatics pipeline consisting of FastQC, STAR, FeatureCounts, edgeR (for miRNA) and DESeq2 (for mRNA). Putative mRNA-miRNA interactions between differentially expressed mRNA and miRNA species were determined using interaction databases miRWalk, miRTarBase, TarBase and TargetScan. …”
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InsectChange: Comment by Gaume, Laurence, Desquilbet, Marion

“…On the basis of a comprehensive review of the original studies, we highlight numerous issues in this database, such as errors in insect counts, sampling biases, inclusion of noninsects driving assemblage trends, omission of drivers investigated in original studies and inaccurate assessment of local cropland cover. …”
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