The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer by Jie Zhu, Jiale Cheng, Yuyuan Ma, Ying Wang, Zhonghua Zou, Wenjie Wang, Haihua Shi, You Meng

“…IL-6, PLR, SII, Ki-67, and lymphocyte count were associated with DFS. The risk score for each TNBC patient was obtained using LASSO regression analysis to construct a prognostic model. …”
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Prognostic evaluation of non-muscle invasive bladder cancer with P-CRP and its nomogram by Junyun Wu, Zhixuan Deng, Xu Lei, Zhiyao Xu, Chenxi Tan, Yunqiao Tang, Xi Sheng, Ning Yang

“…PurposeTo investigate the impact of the product of preoperative platelet count and C-reactive protein (P-CRP) on the postoperative prognosis of patients with non-muscle invasive bladder cancer (NMIBC), and to construct a Nomogram to predict the recurrence-free survival (RFS) of NMIBC patients based on pathological data.MethodsA retrospective analysis was conducted on the clinical data of 164 NMIBC patients who underwent transurethral resection of bladder tumors (TURBT) at the Second Affiliated Hospital of University of South China from January 2013 to December 2019. …”
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Haptoglobin Gene Polymorphism among Sickle Cell Patients in West Cameroon: Hematological and Clinical Implications by Christian Bernard Kengne Fotsing, Constant Anatole Pieme, Prosper Cabral Biapa Nya, Jean Paul Chedjou, Samuel Ashusong, Gisele Njindam, Jocelyn Tony Nengom, Georges Teto, Carine Nguemeni, Wilfred Fon Mbacham, Donatien Gatsing

“…Haptoglobin genotype of 102 SCPs (SS) and 115 healthy individuals (60 AA and 55 AS) was determined by allele-specific polymerase chain reaction, and the complete blood count was determined using the AutoAnalyser. Results showed that the genotype Hp2-2 was significantly (p < 0.05) represented in SS patients (54%) than in controls AA and AS (27% and 29%, respectively), while Hp2-1 was mostly found (p < 0.05) in AS (42%) and AA (38%), against 15% in SS. …”
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Impact of Motivational Enhanced Adherence Counseling and Point-of-Care Viral Load Monitoring on Viral Load Outcome in Women on Life-Long ART: A Randomized Pilot Study by Mercy T. Mutambanengwe-Jacob, Charles C. Maponga, K. Rivet Amico, Bernard Ngara, Nonhlanhla Yende-Zuma, Tariro D. Chawana, Teacler Nematadzira, Justice F. Gumbo, Tendayi Goverayi, Petronella Matibe, Bernadette V. Malunda, Jim Aizire, Taha E. Taha, Mary G. Fowler, Lynda Stranix-Chibanda

“…In an unblinded randomized study, consenting women with last viral load ≥200 copies/ml and/or pill count outside 90–110% range were randomized 1 : 1 to receive the intervention or continue routine care, comprising laboratory-based VL monitoring and standard EAC, from trained nurses and counsellors. …”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

“…Primary outcomes included changes in inflammatory markers (white blood cell count, C-reactive protein, and procalcitonin), imaging outcomes (resolution of pleural effusion, pulmonary inflammation, and the incidence of pleural thickening at three months), pulmonary function assessed by forced vital capacity (FVC), and in-hospital mortality. …”
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Incidence of opportunistic infections and its predictors among HIV/AIDS patients on antiretroviral therapy in Gondar University Comprehensive and Specialized Hospital, Ethiopia by Mequanente Dagnaw, Haileab Fekadu, Adhanom Gebre Egziabher, Tesfaye Yesfue, Meera Indracanti, Alemu Tebeje

“…In terms of predictors, such as a low CD4 count and an advanced WHO stage (II or III), bedridden functional status was found to be significantly associated with OIs.…”
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The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection by Lyudmila V. Lyubimova, Svetlana I. Pavlova, Nikolay S. Nikolaev, Evgeniy A. Lyubimov, Nadezhda N. Pchelova, Vladimir Y. Emelianov

“…The highest diagnostic accuracy in distinguishing between PJI and aseptic loosening was observed in the leukocyte count in synovial fluid (AUC 0.928; 95% CI: 0.837-0.977, p0.0001). …”
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Associations of the levels of adipokines and cytokines in individual follicles with in vitro fertilization outcomes in women with different ovarian reserves by Xuelan Li, Chujun Li, Jie Yang, Min Lin, Xianli Zhou, Ziyang Su, Yuting Zhang, Xinning Li, Xin Chen

“…Patients diagnosed with DOR, defined as a basal antral follicle count < 5 or an anti-Mullerian hormone concentration < 1.1 ng/mL, were assigned to the DOR group, while patients with a normal ovarian reserve (NOR) were assigned to the NOR group. …”
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Imaging and Clinical Characteristics of 8 Cases of COVID-19 Complicated with Pneumomediastinum in Children by FU Qiang, REN Zuolei, LIN Zhiqiang, GONG Jianfeng, WANG Changzheng, WANG Ting, HU Yalan, TAN Jufang

“…When the white blood cell count and hypersensitivity CRP significantly increase, close attention should be paid to respiratory conditions. …”
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Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2 by Huanyu Z. Li, Ashley C. W. Pike, Yung-Ning Chang, Dheeraj Prakaash, Zuzana Gelova, Josefina Stanka, Christophe Moreau, Hannah C. Scott, Frank Wunder, Gernot Wolf, Andreea Scacioc, Gavin McKinley, Helena Batoulis, Shubhashish Mukhopadhyay, Andrea Garofoli, Adán Pinto-Fernández, Benedikt M. Kessler, Nicola A. Burgess-Brown, Saša Štefanić, Tabea Wiedmer, Katharina L. Dürr, Vera Puetter, Alexander Ehrmann, Syma Khalid, Alvaro Ingles-Prieto, Giulio Superti-Furga, David B. Sauer

“…Accordingly, mutations in the S1P transporter SPNS2 are associated with reduced white cell count and hearing defects. SPNS2 also exports the S1P-mimicking FTY720-P (Fingolimod) and thereby is central to the pharmacokinetics of this drug when treating multiple sclerosis. …”
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The Spectrum of Pulmonary Disease in Patients with HIV Infection by Julio Sg Montaner, Leila Spour, Carlos Zala

“…Differential diagnosis of respiratory conditions is significantly facilitated by the prior knowledge of the degree of immunodeficiency present as measured by the CD4 count. In particular, most episodes of PCP occur in patients with absolute CD4 counts below 200 cells/mm3. …”
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Testicular Nitric Oxide and Thiobarbituric Acid Reactive Substances Levels in Obstructive Azoospermia: A Possible Role in Pathophysiology of Infertility

“…Epididymal-aspirated seminal plasma was used for semen count and morphological analysis according to the Kruger criteria. …”
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Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India by Rekha Thapar, Meher Singha, Nithin Kumar, Prasanna Mithra, Bhaskaran Unnikrishnan, Ramesh Holla, Vaman Kulkarni, B. B. Darshan, Avinash Kumar

“…Most of the children orphaned by AIDS (n=78, 90.7%) had a history of both the parents being HIV positive. The median CD4 count of participants at the time of our study was 853.5 (IQR 552–1092) cells/microliter. …”
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Smart packaging tools for selected Indian traditional buffalo milk products: a case for on-package freshness indicators by Narender Raju Panjagari, Ashish Kumar Singh, Sangita Ganguly, Rajan Sharma, Vivek Sharma

“…Among all the freshness indicators, the TCD was found to be very highly positively correlated with titratable acidity, thiobarbituric acid value, free fatty acids value, and total viable bacterial count while significantly negatively correlated with pH, sensory flavor, and overall acceptability scores. …”
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Development and Validation of an MRI‐Based Radiomics Nomogram to Predict the Prognosis of De Novo Oligometastatic Prostate Cancer Patients by Wen‐Qi Liu, Yu‐Ting Xue, Xu‐Yun Huang, Bin Lin, Xiao‐Dong Li, Zhi‐Bin Ke, Dong‐Ning Chen, Jia‐Yin Chen, Yong Wei, Qing‐Shui Zheng, Xue‐Yi Xue, Ning Xu

“…Results Eastern Cooperative Oncology Group (ECOG) score, absolute neutrophil count (ANC) and Rad‐score were included in the nomogram as independent risk factors for OS in de novo oligometastatic PCa patients. …”
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Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Moreover, endometrial morphology and embryo count showed the most pronounced improvement in the H2S treatment group (p < 0.05). …”
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Ejaculatory abstinence duration impacts semen parameters: Insights from a retrospective analysis in male infertility on 23,527 analyses by Giorgio Ivan Russo, Maria Giovanna Asmundo, Andrea Cocci, Ali Saber Abdelhameed, Annalisa Liprino, Filippo Giacone, Debora Lombardo, Antonino Guglielmino, Sandrine Chamayou

“…Group differences were analyzed, focusing on sperm parameters across abstinence periods in normospermic versus patients with sperm abnormalities.ResultsIn normospermic patients we found a trend increase from day 1 to day 7 of abstinence time regarding total sperm count (million) (92.4 vs. 191.1; p&lt;0.01), sperm concentration (million/ml) (44.5 vs. 72.0; p&lt;0.01) and morphology (6 vs. 12.5; p= 0.03) but not regarding motility (A+B) (50.0% vs. 48.0%; p=0.43). …”
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Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia by Nicola Low, Partha Basu, Andreas Limacher, Katayoun Taghavi, Misinzo Moono, Mulindi Mwanahamuntu, Herbert Kapesa, Albert Manasyan, Julia Bohlius, Marie Roumet, Thamsanqa Madliwa, Anne Rutjes

“…A sensitivity analysis considered disease when only visible lesions were biopsied.Results Women included in the study had well-controlled HIV infection (median CD4 count=542 cells/mm3) and all except one were on antiretroviral therapy. …”
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Long-term effects of dupilumab on chronic rhinosinusitis with nasal polyps: A step towards clinical remission by Mona Al-Ahmad, MD, FRCPC, Asmaa Ali, MD, PhD, Wafaa Talat, MD, PhD, Haitham A. Dawood, MD, PhD, Osama Imam, MD, PhD

“…Higher fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC) levels, along with anosmia/hyposmia, predicted larger polyp size. …”
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Tiny clue reveals the general trend: a bibliometric and visualized analysis of renal microcirculation by Bing Wang, Mengting Xu, Sunjing Fu, Yingyu Wang, Hao Ling, Yuan Li, Bingwei Li, Xueting Liu, Qin Ouyang, Xiaoyan Zhang, Ailing Li, Xu Zhang, Mingming Liu

“…The United States, Mayo Clinic, and Lerman Lilach O emerged with the highest publication count, indicating their active collaborations. ‘Type 2 diabetes’ was the most significant keyword cluster, and ‘diabetic kidney disease’ was the largest cluster of cited references. …”
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