Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

“…We determined the sequence identity, DNA and RNA contamination, off-target RNA contamination, and poly-A count with the proposed workflow. <b>Results</b>: Our workflow predicted most of the critical quality controls of mRNA vaccine and plasmid DNA samples, especially focusing on the identity and the nucleotide-based impurities. …”
Get full text

Resource Utilization and Costs of Care prior to ART Initiation for Pediatric Patients in Zambia by Hari S. Iyer, Callie A. Scott, Deophine Lembela Bwalya, Gesine Meyer-Rath, Crispin Moyo, Carolyn Bolton Moore, Bruce A. Larson, Sydney Rosen

“…Patients made, on average, 2.38 clinic visits prior to ART initiation and received 0.81 CD4 tests, 0.74 full blood count tests, and 0.49 blood chemistry tests. The mean cost of pre-ART care was $20 per patient. …”
Get full text

Can deep freezing maintain the quality of two different Iberian pork products over a long storage period? by Ainhoa Sarmiento-García, Beatriz Martínez, Begoña Rubio, Juan-José García-García, Ceferina Vieira

“…Frozen storage time affected microbial quality with different trends depending on the microbial count and the product assessed. An increase in pH value and water holding capacity (p < 0.05) was observed in sirloin at the end of storage, while ‘picadillo’ showed the opposite trend. …”
Get full text

Overwhelming Pulmonary Infection after a Tobogganing Accident by Ravinder Singh, Brian E Louie, William F Bennett, Christopher Allen, Tom Kelly, Christine H Lee

“…Laboratory results showed a white blood cell count of 40×109/L with a left shift. Chest radiography showed a left pleural effusion. …”
Get full text

Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations by Dominica Hudasch, Franz Felix Konen, Nora Möhn, Lea Grote-Levi, Ulrich Wurster, Gabriel Welte, Josef Conzen, Nima Mahmoudi, Thomas Skripuletz, Philipp Schwenkenbecher

“…In addition to central nervous system involvement, all patients exhibited characteristic features of neuroborreliosis like painful meningoradiculitis or peripheral facial palsy. An elevated cell count in cerebrospinal fluid (CSF), positive oligoclonal bands, and blood-CSF barrier dysfunction indicated by an elevated albumin quotient (QAlb) was found in all patients. …”
Get full text

Metabolic consequences and nailfold capillary changes in children with familial Mediterranean fever by Ahmed S. Abo Hola, Rania S. El Zayat, Wafaa Ahmed Shehata, Mai I. Elashmawy, Noha E. Khalaf, Heba M. S. El Zefzaf

“…Results During attack-free periods, patients exhibited higher total leucocytic counts, ESR, CRP, SAA, HOMA-IR, total cholesterol (TC), non-high-density lipoprotein cholesterol (non-HDL-C), Castelli’s risk index I (CRI I), and atherogenic coefficient (AC), and a lower hemoglobin level than controls. …”
Get full text

Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome by Ruth M. Fred-Jiménez, Mariangelí Arroyo-Ávila, Ángel M. Mayor, Grissel Ríos, Luis M. Vilá

“…In addition, the tender point count was higher in the overweight/obese group. In the logistic regression analyses, self-reported memory impairment and urinary frequency differences remained significant after adjusting for confounding variables. …”
Get full text

Value judgment of life quality of women diagnosed with HIV/AIDS in Maceio, Alagoas, Brazil by Cecilio Argolo Júnior, Sonia Maria Soares Ferreira, Vívian Wanderley Teixeira de Albuquerque, Jessyca Ítala Barros Wanderley da Silva

“…Within the construct sensing we observed significant evaluations concerning life satisfaction, concerns about health, financial worries, trust, and sexual function and the following sociodemographic and clinical characteristics: Income, school timing, formal education, work incapacity due to HIH, having a partner, CD4 count and viral load. The results show low quality of life of the women interviewed. …”
Get full text

Endothelial Cell Loss after Phacoemulsification according to Different Anterior Chamber Depths by Hyung Bin Hwang, Byul Lyu, Hye Bin Yim, Na Young Lee

“…Clinical examinations included central corneal thickness (CCT) and endothelial cell count (ECC) preoperatively and 2 months postoperatively. …”
Get full text

Thromboelastography to Monitor Clotting/Bleeding Complications in Patients Treated with the Molecular Adsorbent Recirculating System by Esther B. Bachli, Jörg Bösiger, Markus Béchir, John F. Stover, Reto Stocker, Marco Maggiorini, Eberhard L. Renner, Beat Müllhaupt, Reto A. Schuepbach

“…During MARS therapy median INR increased significantly from 1.7 to 1.9 platelet count and fibrinogen content decreased significantly from 57 fL−1 to 42 fL−1 and 2.1 g/L to 1.5 g/L. …”
Get full text

The Effectiveness of Dipstick for the Detection of Urinary Tract Infection by Isaac Dadzie, Elvis Quansah, Mavis Puopelle Dakorah, Victoria Abiade, Ebenezer Takyi-Amuah, Richmond Adusei

“…Urine cultures with bacteria count ≥105 cfu/ml were classified as “positive” for UTI. …”
Get full text

3,5,4′-Tri-O-acetylresveratrol Attenuates Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome via MAPK/SIRT1 Pathway by Lijie Ma, Yilin Zhao, Ruixuan Wang, Tingting Chen, Wangping Li, Yandong Nan, Xueying Liu, Faguang Jin

“…Lung injuries have been evaluated by histological examination, wet-to-dry weight ratios, and cell count and protein content in bronchoalveolar lavage fluid. …”
Get full text

Obesity as a risk factor for COVID-19 breakthrough infection among the fully vaccinated urban population of South Gujarat – A retrospective cohort study by Mayank Jha, Pratham Kholwadwala, Vatsal Kalariya, Mamta Rani, Jayant Patel, Hitesh Shah, Rushikesh Shukla

“…As high as 144 (17.6%) of respondents were having history of previous infection before vaccination, and around 42 (5.1%) respondents of the overall study population were infected after the first dose of vaccination. The total count of people for infections before receiving a single dose of vaccination irrespective of body status was reported to be 144 (17.6%) out of a total of 818 candidates. …”
Get full text

Disseminated Histoplasmosis as an AIDS-Defining Illness Presenting as Fever of Unknown Origin in an 11-Year-Old Female by Kathryn E. Kalata, Christina Osborne, Amy Willis, Kacey Navarro, Laura Z. Fenton, Christiana Smith

“…Additional testing confirmed the diagnosis of HIV/AIDS with a CD4 count of 52 cells/mm3, complicated by disseminated histoplasmosis. …”
Get full text

Managing Post COVID-19 Patient with Breathlessness by Yen Shen Wong, Muhammad Amin Ibrahim, Mohd Arif Mohd Zim, Mohd Fauzi Abdul Rani

“…Corticosteroid inhaler should be cautioned in this case, in view of recent pneumonia and non-elevated serum eosinophil count. These groups of patients should be closely followed up to unmask interstitial lung disease that may present prior to COVID-19 and worsen post-infection. …”
Get full text

Towards an Integrated <i>Orobanche</i> Management: Understanding Farmers’ Decision-Making Processes Using a Discrete Choice Experiment by Ahmed Yangui, Taheni Mlayeh, Zouhaier Abbes, Mohamed Kharrat

“…While increasing faba bean yields remains a priority, farmers are willing to pay more for IOM scenarios that reduce the <i>Orobanche</i> plant shoot count. In conclusion, there is significant heterogeneity in farmers’ preferences, their financial situation, and the severity of <i>Orobanche</i> infestation significantly influencing their decision. …”
Get full text

Characteristics of strong mine pressure manifestation in composite hard roofs and determination of main controlling layers by LI Yanjun

“…At the square position of the working face, the acoustic emission ringing count of the upper roof decreased by 38.36% compared to pre-splitting of the lower hard roof. …”
Get full text

Primary Mechanism Study of Panax notoginseng Flower (Herb) on Myocardial Infarction in Rats by Xin Zhou, Zhi-Cheng Li, Pei-Pei Chen, Rui-Fang Xie

“…HE (hematoxylin and eosin) staining, immunofluorescent assay, TUNEL assay, quantitative real-time PCR, and western blot analysis were, respectively, performed to observe morphology, count mean minimal vessels, investigate apoptotic cells, and record gene (HIF-1, VEGFA, and KDR) and protein (Bcl-2 and Bax) expressions. …”
Get full text

The average relative dose intensity of R‐CHOP is an independent factor determining favorable overall survival in diffuse large B‐cell lymphoma patients by Monika Długosz‐Danecka, Sebastian Szmit, Tomasz Ogórka, Aleksander B. Skotnicki, Wojciech Jurczak

“…Prolonged intervals between cycles of immunochemotherapy—the most common cause of decreased ARDI (49.3%, 110/223)—were due to neutropenia (absolute neutrophil count <1.0 × 109/L) and infections. Reductions in cytostatic doses were observed in 19.7% (44/223) of patients, mainly as the consequence of cardiotoxicity (23/223, 10.3%). …”
Get full text

Significance of EGFR and PTEN Expression and PLR and NLR for Predicting the Prognosis of Epithelioid Malignant Peritoneal Mesothelioma by Yufei Liang, Guoqi Zheng, Wenjie Yin, Hui Song, Chunying Li, Liang Tian, Dongliang Yang

“…We analyzed the relationships of these markers to age, sex, asbestos exposure, elevated platelet count, ascites, and clinical stage. Results. EGFR and PTEN expressions were positive in 22 (66.67%) and 7 (21.21%) epithelioid MPeM patients, respectively. …”
Get full text