MEK1/2 Inhibitor (GDC0623) Promotes Osteogenic Differentiation of Primary Osteoblasts Inhibited by IL-1β through the MEK-Erk1/2 and Jak/Stat3 Pathways by Zeng-Qiao Zhang, Xiao-Shen Hu, Ye-Chen Lu, Jun-Peng Zhang, Wen-Yao Li, Wei-Yang Zhang, Wei Feng, Dao-Fang Ding, Jian-Guang Xu

“…Cell proliferation levels were evaluated by the cell counting kit 8 (CCK8), EdU assay, and western blotting [proliferating cell nuclear antigen (PCNA) and Cyclin D1]. …”
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Characterization of <i>Clostridium perfringens</i> Phage Endolysin PlyDolk21 by Suyoung Seo, Bokyung Son, Minsuk Kong

“…Additionally, PlyDolk21 effectively reduced the viable cell counts of <i>C. perfringens</i> by 3-log in beef soup and milk samples. …”
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Transcription Factor FXR Activates DHRS9 to Inhibit the Cell Oxidative Phosphorylation and Suppress Colon Cancer Progression by Jinlai Zhao, Yigang Wang, Yang Wang, Jianchao Gao, Haichao Yang, Xiaotang Wu, Hua Li

“…The effects of FXR on the biological function of colon cancer cells were measured by Cell Counting Kit-8, colony formation, and transwell assays. …”
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Effects of Pickleball Intervention on the Self-Esteem and Symptoms of Patients with Schizophrenia by Tsai-Chieh Chien, Chao-Chien Chen

“…However, the Dink test scores in the experimental group showed significant improvements in physical activity capabilities and attention over time, with average hit counts increasing from 5.3 ± 1.5 to 10.7 ± 2.3 (<i>p</i> < 0.01). …”
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Hematological and biochemical variables in hospitalized patients with clinical suspicion of dengue by Rolando Rodríguez Puga, Yoánderson Pérez Díaz, Yanet Pérez Guerrero, Serapio Romero Gavilán

“…<br /><strong>Conclusions:</strong> The analysis allowed verifying significant statistical differences between the values of the leukocyte, neutrophil and lymphocyte counts on admission and on the third day. The enzymes aspartate aminotransferase and gamma glutamyl transferase were elevated in a representative percentage of cases.…”
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Detection of Lactoferrin and Iron in Seminal Plasma and Their Possible Relation to Semen Parameters and Infertility in Varicocele: A Cross-sectional Study by Ali Mohamed Mahran, Marilyn Sameh Abd-Almalak, Fatma Mohammed Helbawi, Marwa Mohammad Mekkawy

“…There was a positive correlation between seminal lactoferrin, iron levels and sperm concentrations and counts. Seminal iron and lactoferrin were significant independent predictors of sperm concentration. …”
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The Effect of A Number Sense Education Program Supported By Web 2.0 Tools on The Number Sense Development of First Grade Elementary School Students by Zuhal Akbabaoğlu, Özgün Uyanık Aktulun

“…However, no significant change was detected in the Counting Skills subdimension (p&gt;.05). Furthermore, a statistically significant difference emerged between the experimental and control groups' post-test average scores in the NSS subdimensions and overall score (p&lt;.05), underscoring the beneficial impact of Web 2.0 Tools-supported educational processes on enhancing number sense skills.…”
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Reproductive ecology of the great reed warbler (Acrocephalus arundinaceus) in the conditions of the drainage canal of the Poltava mining and processing plant by L. M. Litvin, A. B. Chaplygina

“…Methods. Field: bird counts on permanent routes. Statistical: processing of the obtained data. …”
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In Vitro Evaluation of Proliferation and Migration Behaviour of Human Bone Marrow-Derived Mesenchymal Stem Cells in Presence of Platelet-Rich Plasma by Anh Thi Mai Nguyen, Ha Le Bao Tran, Thuy Anh Vu Pham

“…The proliferation of hBMSCs was examined by 2 methods: cell-number counting with the haemocytometer method and the colony-forming unit-fibroblast (CFU-F) assay. …”
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Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway by Yiqing Zhang, Xialu Liu, Zitong Zheng, Haiqiang Huang, Yurou Wang, Shuqin Wu, Yuan Shu, Yuxin Yang, Yufei Zhong, Pengfei Liao, Yongsong Wang, Zezheng Pan

“…The results showed that SDG significantly alleviated POI by improving ovarian indices and follicle counts while protecting against CTX-induced ovarian damage by modulating the PI3K/Akt signaling pathway in KGN cells. …”
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Predicting Interplanetary Shock Occurrence for Solar Cycle 25: Opportunities and Challenges in Space Weather Research by Denny M. Oliveira, Robert C. Allen, Livia R. Alves, Séan P. Blake, Brett A. Carter, Dibyendu Chakrabarty, Giulia D’Angelo, Kevin Delano, Ezequiel Echer, Cristian P. Ferradas, Matt G. Finley, Bea Gallardo‐Lacourt, Dan Gershman, Jesper W. Gjerloev, John Bosco Habarulema, Michael D. Hartinger, Rajkumar Hajra, Hisashi Hayakawa, Liisa Juusola, Karl M. Laundal, Robert J. Leamon, Michael Madelaire, Miguel Martínez‐Ledesma, Scott M. McIntosh, Yoshizumi Miyoshi, Mark B. Moldwin, Emmanuel Nahayo, Dibyendu Nandy, Bhosale Nilam, Katariina Nykyri, William R. Paterson, Mirko Piersanti, Ermanno Pietropaolo, Craig J. Rodger, Trunali Shah, Andy W. Smith, Nandita Srivastava, Bruce T. Tsurutani, S. Tulasi Ram, Lisa A. Upton, Bhaskara Veenadhari, Sergio Vidal‐Luengo, Ari Viljanen, Sarah K. Vines, Vipin K. Yadav, Jeng‐Hwa Yee, James W. Weygand, Eftyhia Zesta

“…In this work, we use a supervised machine learning regression model to predict the number of shocks expected in SC25 using three previously published sunspot predictions for the same cycle. We predict shock counts to be around 275 ± 10, which is ∼47% higher than the shock occurrence in SC24 (187 ± 8), but still smaller than the shock occurrence in SC23 (343 ± 12). …”
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Feeding of dried sweet orange (Citrus sinensis) peel on humoral immune response of broiler chickens by Z. Pourhossein, A. Qotbi, A. Seidavi, V. Laudadio, D. Mazzei, V. Tufarelli

“…Average white blood cell, heterophil, lymphocyte, and monocyte counts, as well as heterophil/lymphocyte (H/L) ratio, were different among treatments. …”
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Altered Intracellular ATP Production by Activated CD4+ T-Cells in Very Preterm Infants by Giulia Aquilano, Maria Grazia Capretti, Francesca Nanni, Luigi Corvaglia, Arianna Aceti, Liliana Gabrielli, Angela Chiereghin, Giacomo Faldella, Tiziana Lazzarotto

“…The neonatal immune system is not fully developed at birth; newborns have adequate lymphocytes counts but these cells lack function. Objective. To assess the activity of T-cells and the influence of the main perinatal factors in very preterm infants (birth weight < 1500 g). …”
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Matrix Metalloproteinase-9 Production following Cardiopulmonary Bypass Was Not Associated with Pulmonary Dysfunction after Cardiac Surgery by Tso-Chou Lin, Feng-Yen Lin, Yi-Wen Lin, Che-Hao Hsu, Go-Shine Huang, Zhi-Fu Wu, Yi-Ting Tsai, Chih-Yuan Lin, Chi-Yuan Li, Chien-Sung Tsai

“…The plasma MMP-9 concentrations significantly elevated at 2–6 h after beginning CPB (P<0.001) and returned to the preanesthesia level at 24 h (P=0.23), with predominant neutrophil counts after surgery (P<0.001). The plasma MMP-9 levels at 4 and 6 h were not correlated with prolonged CPB time and displayed no association with postoperative PaO2/FiO2, regardless of reduced ratio from preoperative 342.9±81.2 to postoperative 207.3±121.3 mmHg (P<0.001). …”
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Detection of Viable but Nonculturable E. coli Induced by Low-Level Antimicrobials Using AI-Enabled Hyperspectral Microscopy by MeiLi Papa, Aarham Wasit, Justin Pecora, Teresa M. Bergholz, Jiyoon Yi

“…The VBNC state was induced by low-level oxidative (0.01% hydrogen peroxide) and acidic (0.001% peracetic acid) stressors for 3 days, confirmed by live-dead staining and plate counting. HMI provided spatial and spectral data, extracted into pseudo-RGB images using three characteristic spectral wavelengths. …”
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Systemic Inflammatory Responses and Lung Injury following Hip Fracture Surgery Increases Susceptibility to Infection in Aged Rats by Hao Zhang, Tiansheng Sun, Zhi Liu, Jianzheng Zhang, Xiaowei Wang, Jia Liu

“…Both sham-operated and injured/surgical group animals underwent intratracheal inoculation with Pseudomonas aeruginosa 1, 3, and 7 days after surgery. P. aeruginosa counts in blood and bronchoalveolar lavage (BAL) fluid and survival rates were recorded. …”
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Ultrasound-assisted enzyme extraction of Dendrobium Officinale polysaccharides: Extraction process, characterization, immunomodulatory effects by Hengpu Zhou, Yingjie Dong, Zhangyun Wu, Xi Peng, Meiqiu Yan, Suhong Chen, Guiyuan Lv

“…It mitigates damage to the thymus and spleen tissues, increases white blood cell counts, regulates the ratio of T lymphocytes and the levels of related factors, enhances macrophage phagocytic function to improve nonspecific immune responses, and boosts the levels of immunoglobulins IgA and IgG to enhance specific immune function. …”
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Alterations of Hematologic and Hematopoietic Parameters in Mice Exposed to Pulsed Electromagnetic Field by Kangchu Li, Zenghui Teng, Zhaohui Liu, Yuxing Zhang, Kaiping Long, Qimei Liao, Ansheng Ni, Guirong Ding, Shirong Ma

“…After PEMF exposure, blood samples and bone marrow cells of mice were collected for hematologic examinations, bone marrow nucleated cell counting, colony-forming units of granulocyte-macrophage (CFU-GM) colony assay, and serum granulocyte-macrophage colony-stimulating factor (GM-CSF) assay. …”
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Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) by Qiyuan Bai, Hao Chen, Zhen Gao, Xuhua Li, Jiapeng Li, Shidong Liu, Bing Song, Cuntao Yu

“…Serum albumin levels and lymphocyte counts were combined to calculate the PNI. We used descriptive statistics categorized by PNI quartiles and performed multivariate logistic regression to adjust for variables including age, gender, ethnicity, and coexisting medical conditions. …”
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The Impact of Grape Maceration on Quality and Biogenic Amine Formation in Slovak Tokaj Wines: Examination of Microbial, Chemical and Sensory Properties by Boris Semjon, Martin Bartkovský, Peter Očenáš, Ivana Regecová, Zuzana Megyesy Eftimová, Jana Výrostková, Lýdia Mesarčová, Mariana Kováčová, Matúš Várady, Lucia Šuľáková, Slavomír Marcinčák

“…Microbiological examination promoted stable yeast counts during the maceration process, ensuring their longer presence during fermentation. …”
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