Contribution of integrase inhibitor use, body mass index, physical activity and caloric intake to weight gain in people living with HIV by Giovanni Guaraldi, Jovana Milic, Elena Bacchi, Federica Carli, Marianna Menozzi, Iacopo Franconi, Alessandro Raimondi, Giacomo Ciusa, Valentina Masi, Michela Belli, Stefano Guaraldi, Emanuele Aprile, Maria Mancini, Cristina Mussini, Jordan E. Lake, Kristine M. Erlandson

“…Of 281 PLWH (74.3% males), mean follow-up was 4.2 years, age 50.3 years, median time since HIV diagnosis 17.8 years, CD4 cell count 630 cells/µL at baseline. PAF for weight gain was the greatest for high BMI (45%, 95% CI: 27–59, p < 0.001), followed by high CD4/CD8 ratio (41%, 21–57, p < 0.001) and lower physical activity (32%, 95% CI 5–52, p = 0.03). …”
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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

“…Baseline demographic data, comorbidities, inflammatory markers (C-reactive protein [CRP], interleukin-6 [IL-6], ferritin, neutrophil-to-lymphocyte ratio [NLR], platelet count, albumin, and derived indices such as the CRP-to-Albumin Ratio [CAR] and Prognostic Nutritional Index [PNI]) were recorded. …”
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Sewage pollution from onsite sewage disposal systems and an offshore wastewater treatment plant outfall in coastal waters of Keaukaha, Hawaiʻi Island by Shayla M.P. Waiki, Steven L. Colbert, Tracy N. Wiegner, Noelani Puniwai, Joseph W.P. Nakoa, III, Nicolas M. Storie, Craig E. Nelson, Ashlynn N. Overly, Karla J. McDermid, Devon K. Aguiar

“…Reported sewage odors coincided with high bacterial count advisories and HWTP discharge events, demonstrating the effectiveness of human olfaction as a sewage pollution indicator. …”
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Outcomes of percutaneous endoscopic gastrostomy (PEG) in HIV patients by Nikhitha Mantri, Haozhe Sun, Sameer Datta Kandhi, Nishant Allena, Muhammad Yasir Anwar, Vibha Hayagreev, Shalini Penikilapate, Ahmed Alemam, Hassan A Muntazir, Trishna Acherjee, Harish Patel, Jasbir Makker

“…This difference occurred despite no notable variations in laboratory parameters such as platelet count and (international normalized ratio), as well as similar usage of anticoagulant or antiplatelet medications between the two groups. …”
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Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma by Nayia Petousi, Nick P Talbot, Ian Pavord, Peter A Robbins, Nicholas M J Smith, Graham Richmond, Asma Alamoudi, Lorenzo Petralia, Haopeng Xu, Dominic Sandhu, Grant AD Ritchie

“…Assessments included prebronchodilator and postbronchodilator CCP and spirometry, and measurements of blood eosinophil count (BEC), fractional exhaled nitric oxide and Asthma-Symptom Questionnaire (ACQ-5).Results Bronchodilation significantly reduced σlnCl, a novel CCP-derived ventilation inhomogeneity index, (ΔσlnCl −0.08, 95% CI (−0.10 to –0.05), p&lt;0.001). …”
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Malignancies in people living with HIV: A 25-years observational study from a tertiary hospital in Italy by Antonio Anastasia, Walter Mazzucco, Luca Pipitò, Santo Fruscione, Roberta Gaudiano, Marcello Trizzino, Maurizio Zarcone, Antonio Cascio

“…No statistical difference was found between the mean values of zenith HIV-RNA and CD4 count in HIV outpatients with cancer and in those without cancer, while a statistically significant difference was found between the HIV-RNA zenith in HIV outpatients with ADC as compared with NADC (10.2 copies/mL versus 8.1 copies/mL; p-value= 0.007). …”
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Clinical outcomes among HIV positive babies below 18 months of age, diagnosed under the Early Infant Diagnosis (EID) programme, India: a mixed-methods studyResearch in context by Suchit Kamble, Nilesh Gawde, Shilpa Bembalkar, Noopur Goel, Mohan Thorwat, Kalyani Nikhare, Sushmita Kamble, Radhika Brahme, Swapna Pawar, Harsh Kubavat, Bhawanisingh Kushwaha, Vinita Verma, Chinmoyee Das, Raman Gangakhedkar

“…Three-year survival was 91%. Baseline CD4 count less than 1500 cells/mm3 had a higher hazard for mortality (hazard ratio 11.39 (CI: 1.45, 89.45), p = 0.021) as well as for either mortality or development of opportunistic infections (hazard ratio 4.87 (CI: 1.56, 15.15), p = 0.006). …”
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Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024 by Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H

“…The United States emerged as the leading country by publication count; Lin Cheng-li ranked first among authors, while China Medical University topped institutional contributions. …”
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Hidden blood loss and risk factors after percutaneous endoscopic transforaminal lumbar interbody fusion by Meng Ge, Meng Ge, Fangbing Zhu, Fangbing Zhu, Weibin Du, Weibin Du, Zhengcong Ye, Zhengcong Ye, Zhenfei Xiong, Zhenfei Xiong, Lukai Zhang, Lukai Zhang, Hua Zhou, Hua Zhou, Jun Yang, Jun Yang

“…The levels of fibrinogen, activated partial thromboplastin time, prothrombin time, thrombin time, and platelet count as well as the pre- and postoperative hematocrit and hemoglobin levels were collected. …”
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Overview of preclinical and phase II clinical studies on Pegmolesatide’s long-term erythropoiesis stimulating effect via EPOR-mediated signal transduction by Xiaoying Ma, Zhen Li, Lu Zhang, Hui Qian, Qinkai Chen, Ye Tao, Yunfan Li, Dandan Wang, Zhizhen Hu, Weili Luo, Ping Li, Hai Yu, Changlin Mei, Xueqing Yu, Yuanfeng Zhou

“…Following a single 0.08 mg/kg dose of Pegmolesatide in BALB/c mice, reticulocyte count, red blood cells, hemoglobin, and hematocrit persisted at elevated levels 4-6 days after administration. …”
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Clinical manifestations of COVID-19 infection and its impact on the outcome in children and adolescents with benign and malignant hematological disease in Egypt: a single-center ex... by Fatma Soliman Elsayed Ebeid, Aya Mostafa, Sondos M. Magdy, Haidy Moahmed Abd El Kader, Amal Abdel Azim Lotfy, Nihal Hussien Aly

“…Baseline laboratory investigation were collected included complete blood count (CBC), liver and kidney functions, C-reactive protein (CRP), serum ferritin, lactate dehydrogenase, and coagulation test. …”
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The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study by Hiroya Kitsunai, Yuka Shinozaki, Sho Furusawa, Naoyuki Kitao, Miki Ito, Hiroyoshi Kurihara, Chiho Oba-Yamamoto, Jun Takeuchi, Akinobu Nakamura, Yumi Takiyama, Hiroshi Nomoto

“…Subjects in the original cohort were divided into groups as follows: subjects with suspected MASLD (alanine aminotransferase > 30 U/L) were placed in an overall group; a subpopulation from an overall group at high risk for hepatic fibrosis (fibrosis-4 (FIB-4) index ≥ 1.3 or platelet count < 200,000/µL) was placed in a high-risk group; and the remaining subjects were placed in a low-risk group. …”
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An Ultra-Low Power, Adaptive All-Digital Frequency-Locked Loop With Gain Estimation and Constant Current DCO by Imran Ali, Hamed Abbasizadeh, Muhammad Riaz Ur Rehman, Muhammad Asif, Seong Jin Oh, Young Gun Pu, Minjae Lee, Keum Cheol Hwang, Youngoo Yang, Kang-Yoon Lee

“…With decrease in frequency resolution, DCO clock counts for each capacitor bank bit evaluation dynamically increases with the proposed technique for accurate frequency tracking. …”
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Intramural pregnancy after intrauterine insemination in a nulligravid patient without previous uterine trauma, complicated by idiopathic thrombocytopenic purpura: A case report by Koyo Yamamoto, Tsuyoshi Takiuchi, Kengo Kiso, Saki Ishii, Satoshi Nakagawa, Yasuto Kinose, Michiko Kodama, Yutaka Ueda, Kenjiro Sawada, Takahiro Tsuboyama, Tadashi Kimura

“…Upon further investigation, the patient was diagnosed with idiopathic thrombocytopenic purpura, presenting with a platelet count of 30,000/μL. Due to the associated risk of hemorrhage, we proceeded with emergency exploratory laparoscopy after platelet transfusion. …”
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Corneal Mucin‐Targeting Liposome Nanoplatforms Enable Effective Treatment of Dry Eye Diseases by Integrated Regulation of Ferroptosis and Inflammation by Yin Zhang, Tinglian Zhou, Kai Wang, Chenqi Luo, Dan Chen, Zeen Lv, Haijie Han, Ke Yao

“…The CF@SNPs treatment comprehensively alleviates DED symptoms, including improving corneal defects, augmenting goblet cell count, and restoring tear secretion. Specifically, CF@SNPs attenuate dry eye pathology by suppressing p53‐SLC7A11‐GSH‐dependent ferroptosis and TNF‐α‐associated inflammatory cascades, accompanied by favorable biocompatibility in vivo. …”
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Effects of in-ovo injection of Yu ping feng polysaccharides on growth performance, intestinal development, and immunity in broiler chickens by Li-Gang Xue, Tian-Kui Guo, Juan Wang, Yu-Quan Shan, Li Guo, Dong-Xing Zhang, Zhong Wei, Dan Wang

“…Furthermore, the YPF group exhibited a statistically significant increase in intestinal IgA+ cell count and flushing fluid SIgA level throughout various time periods compared with those in the other three groups. …”
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Systematic Evaluation of Clinical Efficacy of Shiyiwei Shenqi (Ginseng and Astraglus, Eleven Ingredients) Preparation in Adjuvant Chemotherapy for Malignant Tumor by Bowei HUANG, Yuhui ZENG, Lisha LU, Huijuan GAN

“…Meta analysis results showed that: compared with the control group, the experimental group can increase the clinical stability rate of patients with malignant tumors[<italic>OR</italic>=1.73, 95%<italic>CI</italic>(1.10, 2.73), <italic>P</italic>=0.02], improve the quality of life[<italic>OR</italic>=2.77, 95%<italic>CI</italic>(1.80, 4.28), <italic>P</italic>&lt; 0.000 01], increase the white blood cell count[<italic>OR</italic>=0.41, 95%<italic>CI</italic>(0.27, 0.61), <italic>P</italic>&lt; 0.000 01], increase the hemoglobin content[<italic>OR</italic>=0.38, 95%<italic>CI</italic>(0.23, 0.63), <italic>P</italic>=0.000 2], reduce gastrointestinal reactions[<italic>OR</italic>=0.27, 95%<italic>CI</italic>(0.12, 0.60), <italic>P</italic>=0.000 2], and reduce the incidence of renal function[<italic>OR</italic>=0.27, 95%<italic>CI</italic>(0.12, 0.59), <italic>P</italic>=0.001]. …”
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Prevalence of Diabetes, Prediabetes, and Associated Factors in an Adult Chinese Population: Baseline of a Prediabetes Cohort Study by Xinjie Yu, Fang Duan, Da Lin, Hai Li, Jian Zhang, Qiuyu Wang, Xianglong Wang, Qian Zhao, Jiayu Deng, Guangwei Song, Qingqing Ji, Haihua Zheng, Xiang Chen, Guoyi Zhou

“…The regression analysis showed that older age (relative risk ratio (RRR) = 1.06; 95% CI, 1.01–1.11, P=0.018), higher systolic blood pressure (RRR = 1.04; 95% CI, 1.004–1.08, P=0.030), higher BMI (RRR = 1.20; 95% CI, 1.06–3.06, P=0.004), higher TG (RRR = 1.80; 95% CI, 1.06–3.06, P=0.029), and higher WBC count (RRR = 1.32; 95% CI, 1.07–1.64, P=0.010) were significantly associated with a higher risk of DM. …”
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A Review on Blockchain Applications in Operational Technology for Food and Agriculture Critical Infrastructure by Chengliang Zheng, Xiangzhen Peng, Ziyue Wang, Tianyu Ma, Jiajia Lu, Leiyang Chen, Liang Dong, Long Wang, Xiaohui Cui, Zhidong Shen

“…The United States, China, and India are at the forefront in terms of journal citation counts. Our analysis determined that a reference count of 37 serves as an appropriate threshold. …”
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Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway by Zhuming Chen, Jing Lu, Tianying Chang, Dongmei Zhang, Yibin Zhang, Miao Liu, Tong Wu, Peng Xv, Jian Wang

“…Flow cytometry was utilized to count Th17, Th1, Th2, and Treg cells in lymphocytes. …”
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