Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…Nine risk factors were eventually identified: age, treatment modality, cancer types, history of allergies, age‐corrected Charlson comorbidity index, percentage of eosinophils, absolute number of monocytes, Eastern Cooperative Oncology Group Performance Status, and C‐reactive protein. …”
Get full text

A Hierarchical Behavioral Dynamic Approach for Naturally Adaptive Human-Agent Pick-and-Place Interactions by Maurice Lamb, Patrick Nalepka, Rachel W. Kallen, Tamara Lorenz, Steven J. Harrison, Ali A. Minai, Michael J. Richardson

“…Here we address this challenge by introducing a bioinspired behavioral dynamic model of free-flowing cooperative pick-and-place behaviors based on low-dimensional dynamical movement primitives and nonlinear action selection functions. …”
Get full text

PUBLIC CREDIT GUARANTEES AND BANKING SYSTEM: THE ITALIAN CASE DURING COVID-19 EMERGENCY by ALBERTO BANFI, ALBERTO MARCHESI, FRANCESCA PAMPURINI

“…The study, in a five-year perspective, analyses — in terms of intensity and pervasiveness — the set of such initiatives, both at the entire Italian banking system level and at the specific cooperative banks level, the latter characterized by greater proximity to potentially more fragile customers. …”
Get full text

Research review of network defense decision-making methods based on attack and defense game by Xiaohu LIU, Hengwei ZHANG, Junqiang MA, Yuchen ZHANG, Jinglei TAN

“…Game theory studies the optimal decision-making problem under the condition of conflict confrontation.It is one of the basic theories of cyberspace security, and can provide a theoretical basis for solving the problem of network defense decision-making.The six game characteristics of network attack and defense were defined, such as goal opposition, strategy dependence, non-cooperative relationship, incomplete information, dynamic evolution and interest drive.Based on the hypothesis of rational player and limited resources, a 5-tuple network attack and defense game model was formally defined by using player, attack and defense strategy set, attack and defense action set, attack and defense information set and attack and defense income.The existing conditions of game equilibrium were analyzed, and the general process of network defense decision-making based on attack and defense game model was summarized.The applicable scenarios of network defense decision-making methods based on eight different types of game models were analyzed, such as complete information static game, complete information dynamic game, incomplete information static game, incomplete information dynamic game, evolutionary game, differential game, time game and random game, and summarizes their research ideas.The advantages and disadvantages of network defense decision-making methods based on different types of game models were given.The development process of network defense decision-making method based on attack defense game was summarized, and the advantages and characteristics of defense decision-making method was explained.It were pointed out that there were three problems in the research process, such as the relationship between the number of factors considered in game modeling and the complexity of the model, the dependence of game reasoning on information and data, and the generalization and migration of game model.It also looked forward to the next research direction from the description mechanism of normative strategy, the calculation method of optimizing revenue and the integration with other network security technologies.And the problems that should be solved were explained.…”
Get full text

Effects of acepromazine, xylazine and propofol on spinal reflexes in healthy dogs by Ali Sheykhbahaedinzade, Ali Asghar Sarchahi, Hossein Kazemi Mehrjerdi

“…In aggressive animals, chemical restraint may be necessary due to their non‐cooperative behaviour. However, sedatives may distort the results of examinations. …”
Get full text

Review of presentations and radiotherapy outcomes of patients with malignant spinal cord compression by Louisa M. Mbokazi, Sheynaz Bassa, Krishanthavathie Pillay

“…Most patients presented in a poor Eastern Cooperative Oncology Group (ECOG) performance status (PS 4), de novo disease (63%) and multilevel vertebral involvement (70%). …”
Get full text

The Regional Subsystem Concept: From Heterogeneity to Pluralism by N. S. Labutkin

“…The author identifies the key discussion points, which include primarily the nature of relations between subsystem actors: whether they should necessarily be cooperative or not; if they need formal institutionalization and whether they should be organized hierarchically with a strong leading state. …”
Get full text

Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes by Kerry S. McDonald, Laurin M. Hanft, Timothy L. Domeier, Craig A. Emter

“…PKA increased myocyte power and yielded greater shortening-induced cooperative deactivation in myocytes, which likely provides a myofibrillar mechanism to assist ventricular relaxation. …”
Get full text

Stingless Bee Honey Farming and Farmer Empowerment in Sawahlunto City, West Sumatra, Indonesia by Oktavia Y., Mahdi Mahdi, Astuti N.B., Hidayat R., Yonariza Yonariza, Mutiani C., Anwar H., Goembira F., Arbain A.

“…The study recommends strengthening extension services, offering financial support, and developing cooperative marketing channels to address these challenges. …”
Get full text

Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon by Prathiksha Srikanthan, Suresh Malakondaiah, Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

“…Some of the important areas for future research include improving the methods of early diagnosis, as well as identifying the possibilities of applying the concept of personalized medicine. Multicentre and cooperative work are essential for further improvement of the treatment of OSCC. …”
Get full text

Modeling and Control Strategy for Multiterminal Flexible DC Distribution Network with Echelon Utilization Power Battery by Min Mou, Yuhao Zhou, Wenguang Zheng, Yurong Xie, Shipeng Wang, Lili Liu, Chengzhi Wei

“…To achieve a DC network connection of various types of power supply and load, this paper proposes a starting method of multiterminal flexible DC distribution network and a cooperative control strategy of the wind-solar-storage system. …”
Get full text

Lithuanian's book publishing houses in West Europe in 1945-1952 by Remigijus Misiūnas

“…There were also two cooperative and four stock company publishing houses. …”
Get full text

Doppler Effect Estimation and Compensation for Satellite Systems in Geolocation Problems by Marcello Asciolla, Angela Cratere, Francesco Dell'Olio

“…In particular, the scenario of interest considers a non-cooperative emitter of electromagnetic waves on the surface of the Earth and a receiver able to perform Angle of Arrival measurements embarked on a satellite in Low Earth Orbit. …”
Get full text

Fiber-optic bronchoscopy for diagnosing hilar masses of the lung: a study from a tertiary care cardiothoracic and vascular centre in northeastern India by James Thiek, Mrinmoy Talukdar, Akash Guha

“…Patients with peripheral lung lesions and patients who had a performance status of Eastern Cooperative Oncology Group more than 2 were excluded from the study. …”
Get full text

Exploring the intricacies of plant growth promoting rhizobacteria interactions: an omics review by Kamogelo Mmotla, Nompumelelo R. Sibanyoni, Farhahna Allie, Lungile Sitole, Thendo Mafuna, Manamele D. Mashabela, Msizi I. Mhlongo

“…Scientists are actively exploring and studying how these microorganisms interact and coordinate their activities within the rhizosphere, shedding light on the molecular processes underpinning their cooperative efforts. In this review, we undertake a thorough examination centred on the communication systems that regulate interactions among PGPR in the rhizosphere. …”
Get full text

A bi-level optimization strategy of electricity-hydrogen-carbon integrated energy system considering photovoltaic and wind power uncertainty and demand response by Mingxuan Lu, Yun Teng, Zhe Chen, Yu Song

“…The upper-level model analyzes these uncertainties by modeling short-term and long-term output errors using robust optimization theory, applies an improved stepwise carbon trading model to control carbon emissions, and finally constructs an electricity-hydrogen-carbon cooperative scheduling optimization model to reduce wind and carbon emissions. …”
Get full text

Significance of Baseline and Changes of Tumor Markers and Neutrophil-to-Lymphocyte Ratio in Predicting Overall Survival for Patients with Advanced Pancreatic Adenocarcinoma: A Retr... by Makoto Kadokura, Keisuke Tanaka, Fumitake Amemiya, Shinichi Takano, Mitsuharu Fukasawa, Nobuyuki Enomoto

“…Results: Multivariate analysis revealed that Eastern Cooperative Oncology Group Performance Status 2 (hazard ratio [HR] 4.07, P < 0.01), neutrophil-to-lymphocyte ratio (NLR) ≥3.9 (HR 1.97, P < 0.001), modified Glasgow prognostic score 1–2 (HR 2.77, P < 0.001), carcinoembryonic antigen ≥5.0 (HR 1.44, P = 0.026), carbohydrate antigen 19-9 ≥37 (HR 1.83, P = 0.004), ΔNLR >0 (HR 2.01, P < 0.001), ΔCEA (subtracting the baseline from the start of second cycles of chemotherapy) >0 (HR 1.64, P = 0.002), and ΔCA19-9>0 (HR 1.77, P = 0.002) were independent negative prognostic factors. …”
Get full text

Temozolomide Therapy for Aggressive Pituitary Tumors: Results in a Small Series of Patients from Argentina by Oscar D. Bruno, Lea Juárez-Allen, Silvia B. Christiansen, Marcos Manavela, Karina Danilowicz, Carlos Vigovich, Reynaldo M. Gómez

“…We conclude that TMZ therapy may be of variable efficacy depending on—until now—incompletely understood factors. Cooperative work on a greater number of cases of aggressive pituitary tumors should be crucial to establish the indications, doses, and duration of temozolomide administration.…”
Get full text

Defense Stability and Ecosystem Sustainability in the Strait of Malacca: Maritime Security Challenges from an International Relations Perspective by Awal Syahrul, Sumadinata R. Widya Setiabudi, Yani Yanyan Mochamad, Sudirman Arfin

“…The strait plays a crucial role in global trade and geopolitics; however, the high volume of maritime traffic has led to issues such as maritime security threats, including piracy, smuggling, and geopolitical tensions, as well as environmental threats like marine pollution and ecosystem degradation. Cooperation between coastal countries such as Indonesia, Malaysia, and Singapore through the Cooperative Mechanism has successfully reduced security threats and environmental impacts, though significant challenges remain. …”
Get full text

Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells by Min Shen, Huihui Yu, Yunfeng Jin, Jiahang Mo, Jingni Sui, Xiaohan Qian, Tong Chen

“…Overall, our novel research illuminated the cooperative and synergistic effects of metformin and M2 macrophages on the dynamic balance of bone metabolism.…”
Get full text