A Step-by-Step Equivalent Microprediction Method for the Mechanical Properties of Composite Solid Propellants considering Dewetting Damage by Huiru Cui, Xuan Lv, Yurong Xu, Zhiwen Zhong, Zixiang Zhou, Weili Ma

“…A microscale finite element prediction model of the propellant considering dewetting damage was constructed to study the evolution process of the microdamage of the propellant. …”
Get full text

Dynamic ultrasound-based modeling predictive of response to neoadjuvant chemotherapy in patients with early breast cancer by Xinyi Wang, Yuting Zhang, Mengting Yang, Nan Wu, Shan Wang, Hong Chen, Tianyang Zhou, Ying Zhang, Xiaolan Wang, Zining Jin, Ang Zheng, Fan Yao, Dianlong Zhang, Feng Jin, Pan Qin, Jia Wang

“…We used dynamic ultrasound (US) imaging changes acquired during NACT, along with clinicopathological features, to create a nomogram and construct a machine learning model. This retrospective study included 304 EBC patients recruited from multiple centers. …”
Get full text

Enhanced Inversion of Sound Speed Profile Based on a Physics-Inspired Self-Organizing Map by Guojun Xu, Ke Qu, Zhanglong Li, Zixuan Zhang, Pan Xu, Dongbao Gao, Xudong Dai

“…Subsequently, samples within each cluster are generalized to construct the topology of the solution space for SSP reconstruction. …”
Get full text

2.5-dimensional covalent organic frameworks by Tomoki Kitano, Syunto Goto, Xiaohan Wang, Takayuki Kamihara, Yoshihisa Sei, Yukihito Kondo, Takumi Sannomiya, Hidehiro Uekusa, Yoichi Murakami

“…Here, we show COFs with 2.5-dimensional (2.5D) skeletons, which are microscopically constructed with 3D bonds but have macroscopically 2D planar shapes. …”
Get full text

The homeobox family gene signature predicts the prognosis of osteosarcoma and correlates with immune invasion by Wenda Liu, Kezhou Xia, Xinghan Huang, Zhun Wei, Zicheng Wei, Weichun Guo

“…Four genes (HOXA1, HOXA5, HOXA6, HOXA13) were identified to construct the risk-prognosis model. Patients were categorized into high-risk and low-risk groups, with significantly better prognosis observed in the low-risk group. …”
Get full text

Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice by Mengjie He, Mengying Hu, Tingqiao Wang, Zeping Zuo, Hongkai Li, Zhiwei Zhao, Yunwen Hao, Xueling Dai, Jianfang Wang, Yaxuan Sun

“…The aim of this study was to investigate the potential effects of Morinda officinalis oligosaccharides (MOO) on depression and its concomitant symptom, sexual dysfunction.MethodsChronic unpredictable mild stress (CUMS)-induced depression model was constructed, and the effects of MOO on depression and sexual abilities were evaluated.ResultsThe results revealed that MOO was able to alleviate CUMS-induced depression-like behavior in mice, to inhibit hippocampal neuron apoptosis, to reverse monoamine neurotransmitter imbalance, increase Brain-derived neurotrophic factor (BDNF) expression levels in the hippocampus, to modulate the composition and distribution of gut microbiota, and to increase the abundance of probiotics after continuous gavage of MOO for 28 days. …”
Get full text

A Novel Model-Free Intelligent Proportional-Integral Supertwisting Nonlinear Fractional-Order Sliding Mode Control of PMSM Speed Regulation System by Peng Gao, Xiaodong Lv, Huimin Ouyang, Lei Mei, Guangming Zhang

“…Next, a novel model-free supertwisting nonlinear fractional-order sliding mode control (ST-NLFOSMC) strategy is constructed based on the ultralocal model of PMSM. Meanwhile, a linear extended state observer (LESO) is used to estimate the unknown terms of the ultralocal model. …”
Get full text

Gene drive-based population suppression in the malaria vector Anopheles stephensi by Xuejiao Xu, Jingheng Chen, You Wang, Yiran Liu, Yongjie Zhang, Jie Yang, Xiaozhen Yang, Bin Chen, Zhengbo He, Jackson Champer

“…Abstract Gene drives are alleles that can bias the inheritance of specific traits in target populations for the purpose of modification or suppression. Here, we construct a homing suppression drive in the major urban malaria vector Anopheles stephensi targeting the female-specific exon of doublesex, incorporating two gRNAs and a nanos-Cas9 to reduce functional resistance and improve female heterozygote fitness. …”
Get full text

Predicting Flash Point of Organosilicon Compounds Using Quantitative Structure Activity Relationship Approach by Chen-Peng Chen, Chan-Cheng Chen, Hsu-Fang Chen

“…In this work, the FPs of 236 organosilicon compounds were collected and used to construct a quantitative structure activity relationship (QSAR) model for predicting their FPs. …”
Get full text

What can mathematical models tell us about the relationship between circular migrations and HIV transmission dynamics? by Aditya S. Khanna, Dobromir T. Dimitrov, Steven M. Goodreau

“…Two modeling classes have dominated the HIV epidemiology and policyliterature for the last decade: one a form of compartmental models,the other network models. We construct models from each class, usingordinary differential equations and exponential random graph models,respectively. …”
Get full text

Massively Parallel Screening of Toll/Interleukin‐1 Receptor (TIR)‐Derived Peptides Reveals Multiple Toll‐Like Receptors (TLRs)‐Targeting Immunomodulatory Peptides by Yun Lim, Tae Kyeom Kang, Meong Il Kim, Dohyeon Kim, Ji Yul Kim, Sang Hoon Jung, Keunwan Park, Wook‐Bin Lee, Moon‐Hyeong Seo

“…A large peptide library is constructed, named TIR surfacesome, by tiling surface sequences of the large TIR domain family and screening against MALTIR and MyD88TIR, TIRs of two major TLR adaptor proteins, resulting in the discovery of hundreds of TIR‐binding peptides. …”
Get full text

Increasing of Pulsed Laser Source Peak Power by Use of Ring Fiber-Optic Delay Line by V. A. Alekseev, M. R. Zaripov, A. S. Perminov, E. A. Sitnikova, V. P. Usol’tsev, S. I. Yuran

“…Objective of this work was estimating energy effectiveness of laser systems, which based on this method.General constructing method of the laser pulsed laser source with ring fiber delay line is considered, its block diagram and the general operating principle of similar systems are presented. …”
Get full text

Lemon-derived nanoparticle-functionalized hydrogels regulate macrophage reprogramming to promote diabetic wound healing by Enyou Jin, Yusheng Yang, Shengjie Cong, Dengke Chen, Ruixiong Chen, Jun Zhang, Yanjun Hu, Weini Chen

“…To solve the problems of continuous drug delivery and penetration depth, Lemon Exosomes were loaded into a hydrogel constructed of Gelatin Methacryloyl (GelMA) and Dialdehyde Starch (DAS) that closely fits to the skin, absorbs water, swells, and is moist and breathable, effectively promoting the sustained and slow release of exosomes and resulting in excellent performance for diabetic wound healing. …”
Get full text

Evaluation of a Three-Stage Method for Improving Mandibular Retrognathia with Labially Inclined Incisors Using Genioplasty, Segmental Osteotomy, and Two-Jaw Surgery by Kazuhiro Matsushita, Hiro-o Yamaguchi, Mino Koshikawa-Matsuno, Nobuo Inoue

“…We have previously described a three-stage method to overcome this problem, involving genioplasty for improving the retruded chin, and to construct the infrastructure for subsequent subapical segmental alveolar osteotomy, subapical segmental alveolar osteotomy itself, and, finally, two-jaw surgery. …”
Get full text

A Survey on the Modeling of Magnetic Tunnel Junctions for Circuit Simulation by Hyein Lim, Seungjun Lee, Hyungsoon Shin

“…Some behavioral models are constructed by adding fitting parameters or introducing new physical parameters to represent the complex switching behavior of an MTJ over a wide range of input current conditions. …”
Get full text

A Negative Capacitance Field-Effect Transistor with High Rectification Efficiency for Weak-Energy 2.45 GHz Microwave Wireless Transmission by Hualian Tang, Ailan Tang, Weifeng Liu, Jingxiang Huang, Jianjun Song, Wenjie Sun

“…Based on the optimized NCFET, a half-wave rectifier circuit employing a novel diode connection configuration was constructed and verified through transient simulations. …”
Get full text

Oriented ice eddy detection network based on the Sentinel-1 dual-polarization data by Jinqun Wu, Jinqun Wu, Yiqin Zheng, Tingting Wang, Chunyong Ma, Chunyong Ma, Ge Chen, Ge Chen

“…Secondly, an automatic ice eddy detection method based on oriented bounding boxes (OBB) was constructed to identify the ice eddy and output features such as horizontal scales, eddy centers and rotation angles. …”
Get full text

Increased vulnerability of Arctic potential ice roads under climate change by Yuanbiao Dong, Pengfeng Xiao, Xueliang Zhang, Daqing Ge, Junchuan Yu, Yangyang Chen, Qiong Wu, Yanni Ma, Rongyuan Liu, Wenbo Luan, Hao Liu, Jie Bai

“…In the context of the Arctic amplified warming, the vulnerability of potential ice roads under the influence of complex climate system remains unclear. Here, we construct a potential ice road assessment model that allows quantization of the climatic suitability of potential ice roads in the Arctic. …”
Get full text

Historical shoreline analysis in selected areas on the east coast of Albay, Philippines by Antonino B. Mendoza Jr., Joshua K. B. Bista, Skorzeny C. De Jesus, María Luisa U. Tango

“…Natural processes, including storm surges and sediment transport, were compounded by human activities such as sand mining, urban expansion, and coastal road constructions, resulting in the degradation, fragmentation and loss of vital coastal ecosystems. …”
Get full text

Calibration of a groundwater flow model in a karst aquifer using EPM approach: Case of Elhajeb-Ifrane aquifer, Morocco by Ammari Zakaria, Oumou Abdellah, Essahlaoui Narjisse, El Fakir Rabia, Mili El Mostafa, Essahlaoui Ali, Kassou Amina, Van Rompaey Anton

“…The groundwater flow model was constructed using a Python package and was calibrated using the parameter estimation code. …”
Get full text