Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial by Lauren Bloomfield, Julie Boston, Martin Masek, Lesley Andrew, Donna Barwood, Amanda Devine

“…Serious games could represent a constructive tool to help teachers impart specialized health education.…”
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Log odds of positive lymph nodes compared to positive lymph node ratio and number of positive lymph nodes in prognostic modeling for patients with NSCLC undergoing lobectomy or tot... by Qiming Huang, Shai Chen, Zhenjie Li, Longren Wu, Dongliang Yu, Linmin Xiong

“…An XGBoost model was constructed to predict overall survival in patients using three features: LODDS, LNR, and PLN. …”
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3D-AttenNet model can predict clinically significant prostate cancer in PI-RADS category 3 patients: a retrospective multicenter study by Jie Bao, Litao Zhao, Xiaomeng Qiao, Zhenkai Li, Yanting Ji, Yueting Su, Libiao Ji, Junkang Shen, Jiangang Liu, Jie Tian, Ximing Wang, Hailin Shen, Chunhong Hu

“…Deep learning models with double channel attention modules based on MRI (AttenNet) for predicting PCa and csPCa were constructed separately. Each model was first pretrained using 1144 PI-RADS 1–2 and 4–5 images and then retrained using 238 PI-RADS 3 images from three training centers (centers 1–3), and tested using 185 PI-RADS 3 images from the other three testing centers (centers 4–6). …”
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The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases by Yezhou Ding, Mingyang Feng, Wanqing Chi, Xiaoyin Wang, Baoyan An, Kehui Liu, Shike Lou, Xiaolin Wang, Hui Wang

“…Immunohistochemistry (IHC) was performed on clinical samples to validate the differential expression of METTL17 in HCC and normal tissues. Ultimately, we constructed a METTL17-related risk-score model of HCC and validated its prognostic classification efficiency. …”
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‘Queer Reverence’: Aubrey Beardsley’s Venus and Tannhäuser by Nicole Fluhr

“…Instead, the land ‘under the hill’ is constituted as a genuinely alternative paradise, a counterpublic of perverts who communally flout the dictates of heteronormativity, together constructing a world that does not simply exclude shame, guilt, and sin but disavows them entirely.…”
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Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1... by Wangcheng Hu, Hui Luo, Yuekun Yang, Qiong Wang, Ni Hong, Guoping Wang, Aiming Wang, Liping Wang

“…To investigate the role of RNA-silencing in B. dothidea defense, we constructed four small RNA libraries and sequenced B. dothidea micro-like RNAs (Bd-milRNAs) produced in response to BdCV1 and BdPV1 infection. …”
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Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study by Si Chen, Rui Nie, Xiaoran Shen, Yan Wang, Haixia Luan, Xiaoli Zeng, Yanhua Chen, Hui Yuan

“…Predictive models were constructed using machine learning algorithms, and SHapley Additive exPlanations (SHAP) analysis was applied to evaluate the contributions of age and RDW levels to mortality in this patient population. …”
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Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer by Ram Patel, John Mathews, Caroline Hamm, Swati Kulkarni, Rasna Gupta, Tarquin Opperman, John Dean Chiong, Abdullah Nasser

“…Cox proportional hazards models were constructed to adjust for confounding factors. Results: Seventy-five patients were included in the final analysis. …”
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Exploring multi-level factors determining social participation of students with intellectual disabilities in inclusive physical education classes by Christoffer Klenk, Matthias Buser

“…In specific, social participation (SP) – a construct comprising of contacts, friendships, self-perception and acceptance (Koster et al., 2009) – has yet not been accomplished. …”
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Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy by Jian Cheng, Miaomiao Sun, Xiao Dong, Yang Yang, Xiaohan Qin, Xing Zhou, Yongcheng Fu, Yuanyuan Wang, Jingyue Wang, Da Zhang

“…A prognostic signature, SRPS, was constructed and validated using machine-learning approaches. …”
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Aspergillus fumigatus Influences Gasdermin-D-Dependent Pyroptosis of the Lung via Regulating Toll-Like Receptor 2-Mediated Regulatory T Cell Differentiation by Wei Yan, Yi-si Zhao, Ke Xie, Yu Xing, Fang Xu

“…The mouse model of A. fumigatus infection was constructed by tracheal instillation. The pathological changes in the lungs of the mice were observed under a microscope. …”
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Framework for smartphone-based grape detection and vineyard management using UAV-trained AI by Sergio Vélez, Mar Ariza-Sentís, Mario Triviño, Antonio Carlos Cob-Parro, Miquel Mila, João Valente

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Analisis Kinerja Augmented Reality HyperText Markup Language (ARHTML) Melalui Pemanfaatan Web Graphics Library dan OpenGl Shading Language untuk Pengembangan 3D by Multohadi Hamzaturrazak, Abdul Jabbar, Rizal Setya Perdana, Aryo Pinandito

“…The implemented shaders are combined with Three.js and AR.js tools to construct a captivating augmented reality atmosphere. …”
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Development and Validation of Risk Stratification for Heart Failure After Acute Coronary Syndrome Based on Dynamic S100A8/A9 Levels by Jie Ma, Ke Ma, Jing Chen, Xinying Yang, Fei Gao, Hai Gao, Hui Zhang, Xin‐Liang Ma, Jie Du, Ping Li, Yulin Li

“…S100A8/A9 is not only rapidly released after myocardial ischemia, but is also involved in reperfusion injury, which is an important predictor of HF after ACS. We attempted to construct a reliable HF risk stratification tool for evaluating patients with ACS after reperfusion therapy based on S100A8/A9 dynamic changes. …”
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Employee retention through effective human resource management practices in Maldives: Mediation effects of compensation and rewards system by Zubair Hassan

“…ORIGINALITY AND VALUE: This could be one of the pioneering studies carried out in the retail sector of Maldives by examining the four constructs of human resource management practices to shed light on how retail sector business organizations in Maldives make decisions on improving employee retention. …”
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Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

“…In vitro experiments, human aortic smooth muscle cells were extracted, and an in vitro dissection model was constructed with angiotensin II. siRNA silencing studies were performed to investigate the effects of MR-1 and ROCK1 on the development of AD and their interconnections.Results: Analysis of aortic tissues revealed significantly elevated levels of MR-1 and ROCK1 in AD patients, and meanwhile the inflammatory indexes showed the same trend. …”
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DepITCM: an audio-visual method for detecting depression by Lishan Zhang, Lishan Zhang, Zhenhua Liu, Yumei Wan, Yunli Fan, Diancai Chen, Qingxiang Wang, Kaihong Zhang, Yunshao Zheng

“…The resolution of these issues is crucial for constructing models of depression detection.MethodsIn this paper, we propose a multi-task representation learning based on vision and audio for depression detection model (DepITCM).The model comprises three main modules: a data preprocessing module, the Inception-Temporal-Channel Principal Component Analysis Module(ITCM Encoder), and a multi-task learning module. …”
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Using Health Utility Index (HUI) for Measuring the Impact on Health-Related Quality of Life (HRQL) Among Individuals with Chronic Diseases by Frank Mo, Bernard C.K. Choi, Felix C.K. Li, Joav Merrick

“…The Health Utilities Index (HUI) is a recently developed system for measuring the overall health status and health-related quality of life (HRQL) of individuals, clinical groups, and general populations. Using the HUI (constructed based on eight attributes: vision, hearing, speech, mobility, dexterity, cognition, emotion, and pain/discomfort) to measure the HRQL for chronic disease patients and to detect possible associations between HUI system and various chronic conditions, this study provides information to improve the management of chronic diseases.This study is of interest to data analysts, policy makers, and public health practitioners involved in descriptive clinical studies, clinical trials, program evaluation, population health planning, and assessments. …”
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Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma by Simin Li, Yang Wang, Rui Sun, Debora Franceschi, Hongying Pan, Chenxuan Wei, Anthony Chukwunonso Ogbuehi, Bernd Lethaus, Vuk Savkovic, Sebastian Gaus, Rüdiger Zimmerer, Dirk Ziebolz, Gerhard Schmalz, Xiao Jiang

“…Single-cell pseudotime trajectories were constructed with MONOCLE (version 2.6.4). Cell-cell interactions were analyzed with CellChat R package. …”
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miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF-κB Signaling Pathway by Jie Bian, Weizhong Ge, Zhengmei Jiang

“…The in vivo animal models for DR were constructed using streptozotocin-induced diabetic C57BL/6 mice. …”
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