Large-scale spatio-temporal variation in vital rates and population dynamics of an alpine bird by Nater, Chloé R., Frassinelli, Francesco, Martin, James A., Nilsen, Erlend B.

“…Here, we developed a multi-area version of a recently developed integrated distance sampling model (IDSM) and applied it to data from a large-scale participatory monitoring program – the “Hønsefuglportalen” – to study spatio-temporal variation in population dynamics of willow ptarmigan (Lagopus lagopus) in Norway. We constructed an open and reproducible workflow for exploring temporal, spatial (latitudinal, longitudinal, altitudinal), and residual variation in recruitment, survival, and population density, as well as relationships between vital rates and relevant covariates and signals of density dependence. …”
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Identifying the causes and consequences of pregnancy in Iranian Kurdish women under the age of 18: A grounded theory study by Javad Yoosefi lebni, Ahmad Ahmadi, Seyed Fahim Irandoost, Mandana Saki, Hossein Safari, Nafiul Mehedi

“…Results: After the data analysis and coding process, the conceptual model of causes and consequences of pregnancy in adolescents emerged, including 1) predisposing conditions (sociocultural factors: Social learning, misconceptions about fertility and childbirth, preventing stigma), 2) causal conditions (individual factors: lack of knowledge on how to prevent pregnancy, improper use of contraceptives, inadequate knowledge about the risks of pregnancy in adolescence, fear of the side effects of using contraceptives, filling the vacuum of loneliness, family factors: husband's and his family's pressure, committing her husband to life, consolidating her position in family), 3) intervening conditions (structural factors: no barriers to pregnancy, difficult access to contraceptives), 4) strategies and interactions (positive reactions: trying to prepare herself for raising a child, taking better care of herself and her child, negative reactions: trying to kill herself and the kid, fear and concealment), and 5) consequences (destructive consequences: threats to the health of the child, threat to mother's health, inadequate access to health services, constructive consequences: increase of support, strengthen the sense of empowerment). …”
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Clinical and molecular characteristics and long-term outcomes of pediatric intracranial meningiomas: a comprehensive analysis from a single neurosurgical center by Leihao Ren, Jiaojiao Deng, Hiroaki Wakimoto, Qing Xie, Ye Gong, Lingyang Hua

“…Univariate and multivariate Cox analyses were employed to evaluate the predictive values of clinicopathological characteristics. A nomogram was constructed and its predictive accuracy evaluated. Result 40 females (54.1%) and 34 males (45.9%) patients, with the gender ratio of 1.18:1, were identified. 9 (12.2%) cases were clinically diagnosed as NF2-related Schwannomatosis (NF2-SWN), while 65 (87.8%) were sporadic. …”
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Neonatal indicator data in Tanzania District Health Information System: evaluation of availability and quality of selected newborn indicators, 2015-2022 by Josephine Shabani, Nahya Salim, Christine Bohne, Louise Tina Day, Claud Kumalija, Ahmad Mohamed Makuwani, Felix Bundala, Habib Ismail, Joy E. Lawn, Eric O. Ohuma

“…To address these challenges, it is crucial to strengthen routine data review, implement robust quality checks, enhance validation processes, provide targeted training, deliver constructive feedback, and conduct supportive supervision. …”
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Assessing the effect of On-site supportive communication training (On-site SCT) on doctor burnout: a randomized controlled trial by K.K. Antonsen, J.D. Lyhne, A.T. Johnsen, S. Eßer-Naumann, L.Ø. Poulsen, L. Lund, S. Timm, L.H. Jensen

“…Pre- and post-intervention assessments on burnout (Copenhagen Burnout Inventory) were conducted, as were assessments of related constructs (job satisfaction and communication self-efficacy). …”
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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…A competing endogenous RNA (ceRNA) network was constructed using microRNA (miRNA) target prediction databases (miRanda, miRTarbase, miRcode) and sequencing results. …”
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Soil classification in a seismically active environment based on join analysis of seismic parameters by Y. Asnawi, A.V.H. Simanjuntak, U. Muksin, M. Okubo, S.I. Putri, S. Rizal, M. Syukri

“…The classification of soil properties from the combination of shear wave and horizontal-to-vertical spectral ratio data correlates with the geology of the study area.CONCLUSION: The Banda Aceh city, flanked by the two active faults, is characterized by low shear wave velocity and high amplification because the city stands on the sedimentary basin; thus, it requires a detailed investigation prior to constructing infrastructures. The other clusters are located on the relatively less vulnerable areas, indicated by moderate shear wave velocity and moderate to low seismic vulnerability indexes. …”
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Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…This research aims to restore intestinal microbiota to a healthy state through the oral administration of Bifidobacterium in the early stages with the goal of delaying the onset and progression of RA.MethodsCollagen-induced arthritis (CIA) rat model was constructed to assess the development of RA using arthritis clinical scores, paw thickness, pathological analysis of knee joint. …”
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Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients by Wang Z, Lan T, Zhang Y, Guo Z, Yu H, Sun G, Wang Z, Yan Z, Tao Q, Xu Y

“…A multivariable logistic regression model was constructed to determine whether there is a true association between OA, degree of fatigue, and pain level in FMS patients. …”
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Factors Influencing Telemedicine Adoption Among Health Care Professionals: Qualitative Interview Study by Fiona Schürmann, Daniel Westmattelmann, Gerhard Schewe

“…Existing studies focus on patient perspectives or general adoption factors, neglecting the complex interplay of contextual variables and trust constructs influencing HCPs’ telemedicine adoption. …”
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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…A three-generation pedigree that includes details such as the year of cancer diagnosis, age at diagnosis, cancer type, survival status of family members and age at death will be constructed for each participant. The collected data will be linked to secondary sources such as cancer registries and National Health Insurance Service data to provide a comprehensive analysis of the impact of hereditary cancer on health and survival.Ethics and dissemination The study protocol was approved by all the Ethics Committees: the National Cancer Center IRB (NCC2023-0179), the Samsung Medical Center IRB (SMC2023-09-057), the Yonsei University Health System, Severance Hospital IRB (4-2023-0627), the Hanyang University Guri Hospital IRB (GURI2023-08-021) and the Keimyung University IRB (DSMC IRB 2024-05-048). …”
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Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease by Jia Mao, Yufei Zhou, Licheng Lu, Ping Zhang, Runhua Ren, Yaqiong Wang, Jing Wang

“…Subsequently, a protein-protein interaction (PPI) network was established to screen out on which hub genes enrichment analyses should be performed, and a ceRNA network (lncRNA/circRNA-miRNA-mRNA) was constructed to elucidate ceRNA axes in CHD. Results. …”
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miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis by ZhiYu Zhao, BoXia Li, DianWei Cheng, YuFang Leng

“…Subsequently, the target gene miRNA-541-5p was obtained by miRNA sequencing screening, and further validation revealed that miRNA-541-5p expression was increased in the myocardial tissues of rats in the I/R injury model group compared with those of rats in the NC group, P < 0.05. Subsequently, by constructing H9C2 cell lines with miRNA-541-5p overexpression and miRNA-541-5p expression inhibition, miRNA-541-5p expression was inversely correlated with the survival of H9C2 cells after hypoxia-reoxygenation injury. miRNA-541-5p up-regulation led to a decrease in SOD and GSH, an increase in ferritin and MDA, and an accumulation of ROS. wb and qRT-PCT demonstrated that high miRNA-541-5p expression up-regulated the expression of protein/mRNA expression of ACSL-4, HO-1, ferritin, and TFR-1, but down-regulated protein/mRNA expression of GPX-4. …”
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Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation by Chaowang Zhou, Ruqian Zhong, Lei Zhang, Renyi Yang, Yuxin Luo, Huijun Lei, Liang Li, Jianzhong Cao, Zhiying Yuan, Xiaoning Tan, Mengzhou Xie, Haoyu Qu, Zuomei He

“…Secondly, GO and KEGG enrichment analysis of RDEGs were performed, and protein–protein interaction networks (PPIs) were constructed to identify and visualize hub RDEGs. Then, molecular docking between hub RDEGs and RosA was performed, and further evaluation was carried out by using bioinformatics for the predictive value of the hub RDEGs. …”
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Spectroscopic analysis (UV-VIS-NIR) for predictive modeling of macro and micronutrients in grapevine leaves by J.I. Manzano, M. Rodríguez-Febereiro, M. Fandiño, M. Vilanova, J.J. Cancela

“…Partial Least Squares Regression (PLS-R) was employed to construct models for the concentrations of these nutrients based on the reflectance measurements of the leaves. …”
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Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid by Yanqing Xia, Hongwu Tian, Yanlei Li, Xinru Yang, Jinming Liu, Chunli Liu, Li Zhou, Lincai Zhang, Tiejian Li, Tiesheng Shi

“…The species versus pH and reactivity of species versus pH distribution diagrams were constructed, demonstrating that the species ‒SCH2CH2SO3‒ of Mesna largely governs the total reactivity when pH > 5; in contrast, the form of Mesna per se (mainly as HSCH2CH2SO3‒) makes a negligible contribution. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…The objective of this study was to evaluate the psychometric performance of the QOL-E in patients with LR-MDS.MethodsData from four clinical trials in MDS (MEDALIST, DARB-MDS, EQoL-MDS, and RevMDS trials) were used to assess construct validity, reliability, and responsiveness. …”
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Glucagon-Like Peptide-2 Analogue ZP1849 Augments Colonic Anastomotic Wound Healing by Marie Kjaer, Wayne Russell, Peter Schjerling, Elena Cottarelli, Kennet N. Christjansen, Ditte M. G. Olsen, Peter-Martin Krarup, Lene Jessen, Mark Berner-Hansen, Lars N. Jorgensen, Magnus S. Ågren

“…Eighty-seven male Wistar rats were stratified into four groups and received daily treatment with vehicle or ZP1849 starting one day before (day -1) end-to-end anastomosis was constructed in the left colon on day 0, and on days 0 (resected colon segment), 3, and 5, gene expressions of GLP-2R, Ki67, insulin-like growth factor- (IGF-) 1, type I (COL1A1) and type III (COL3A1) procollagens, cyclooxygenase- (COX-) 1, COX-2, and matrix metalloproteinase- (MMP-) 7 were quantified by RT-qPCR. …”
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How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach by Qian Bai, Qian Bai, Lieyu Huang, Yan Guo, Xin Xu, Zhouyixin Zhang, Yuan Wang, Hao Chen, Ying Bian, Ying Bian

“…Meanwhile, in the context of restricted public health resources, how to efficiently utilize these resources becomes a paramount concern.ObjectiveThis study aimed to evaluate the technical efficiency of specialized public health facilities, the major providers of public health services in China, then discuss its temporal and spatial distribution characteristics and finally investigate its influencing factors.MethodsThe super slacks-based measure data envelopment model was constructed to calculate the efficiency of specialized public health facilities of 31 provinces from 2017 to 2019. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…Attenuated live vaccines are capable of eliciting robust immune protection against SE.MethodsIn this study, an mcpC gene deletion strain (ΔmcpC) was constructed by the wild strain C50336, to evaluate its potential as a genetically engineered attenuated live vaccine. …”
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