IL-17 triggers PD-L1 gene transcription in NSCLC cells via TRIM31-dependent MEF2C K63-linked polyubiquitination by Shuai Ying, Ningxia Wu, Yuting Ruan, Wen Ge, Pei Ma, Tongpeng Xu, Yongqian Shu, Yingwei Wang, Wen Qiu, Chenhui Zhao

“…The corresponding plasmids were constructed and identified. An isograft model was used to verify the findings in vitro. …”
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The prognostic role of vasculoendothelial growth factor A in patients with ST-segment elevation acute myocardial infarction during 6-months follow-up period by N.P. Kopytsya, I.M. Кutya, I.V. Rodionova, Ya.V. Hilova

“…The prognostic model for the development of adverse events during 6 months follow-up is constructed, with inclusion of the VEGF-A, LDL-C concentration and complications in the acute period of the disease, increases the accuracy of prediction power predominantly because of higher specificity.…”
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Predicting Treatment Outcomes in Patients with Low Back Pain Using Gene Signature-Based Machine Learning Models by Youzhi Lian, Yinyu Shi, Haibin Shang, Hongsheng Zhan

“…From these genes, 45 machine learning models were constructed using different combinations of feature selection methods and classification algorithms. …”
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Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1 by Hong Zhou, Jiaxin Zhou, ShanShan Liu, Jing Niu, Jinghua Pan, Ruiman Li

“…A mouse model of RSA was constructed for confirmation. Finally, we analyzed the correlations between serum hsa-miR-532-3p levels and the clinical features of pregnant women with RSA. …”
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Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…And then, we adopted the quantitative real-time PCR (RT-qPCR) assay to validate the hub genes among several CKD animal models. Furthermore, we constructed a competitive endogenous RNA (ceRNA) network for the hub genes utilizing the ENCORI and miRDB databases, while also calculating Spearman correlation coefficients. …”
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Preliminary study on the coconut crab (Birgus latro) rearing in captive pond by . Sulistiono, M.M. Kamal, Nurlisa A. Butet

“…The rearing activity was done in captive pond sized 5x5x1.3 m3 divided into 22 smaller ponds sized 1x1x1.3 m3 with a hiding hole (constructed by pile stones), supported by two small ponds sized 30x40x40 cm3 for sea and fresh water stocks, respectively.  …”
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Mediating effects of occupational self-efficacy on the relationship of authentic leadership and job engagement by Popy Podder, Hillol Saha

“…Moreover, the findings of this study depict the importance to understand the constructions like leaders' authenticity that lead to the promotion of confidence in their employees and, as such, an increase in their JE and performance. …”
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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Seven machine learning models were constructed and evaluated using receiver operating characteristic (ROC) curves and decision curve analysis (DCA). …”
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Simulation and Test of Key Decorticating Components of Spiral Ramie Decorticator by Wenlong Zheng, Lan Ma, Jiajie Liu, Bo Yan, Yiping Duan, Sixun Chen, Jiangnan Lyu, Wei Xiang

“…The Box–Behnken experimental design method was used to construct a mathematical model describing the effects of the decorticating drum rotation speed and the decorticating gap on the fiber percentage of fresh stalk, and the optimal operating parameters were determined accordingly. …”
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Use of Texture Analysis on Noncontrast MRI in Classification of Early Stage of Liver Fibrosis by Ru Zhao, Xi-Jun Gong, Ya-Qiong Ge, Hong Zhao, Long-Sheng Wang, Hong-Zhen Yu, Bin Liu

“…After statistical analyses, final diagnostic models were constructed. Receiver operating curves (ROCs) and areas under the ROC (AUCs) were used to assess the diagnostic value of each final model and 100-time repeated cross-validation was applied to assess the stability of the logistic regression models. …”
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Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway by Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao

“…Methods: Lentiviruses carrying 3β-hydroxysteroid-Δ24 reductase-complementary DNA (DHCR24-cDNA), DHCR24-short hairpin RNA (DHCR24- shRNA) or empty lentiviral vectors were transfected into SHSY-5Y cells in order to construct DHCR24 knock-down and knock-in models, along with corresponding controls. …”
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Design and psychometric testing of a moral intelligence instrument for pre-hospital emergency medical services personnel: a sequential-exploratory mixed-method study by Fateme Mohammadi, Rasoul Salimi, Salman Khazaei, Mostafa Bijani

“…It was in the second phase where the psychometric properties including face validity, content validity, construct validity and reliability were measured. A total of 210 prehospital EMS personnel participated for exploratory and confirmatory factor analysis. …”
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The Innovation Intermediaries Role in the Adoption of Emerging Technologies in Iran's Automotive Industry by Ali Maleki, Hadi Nilforoushan

“…It is worth mentioning that to test the hypotheses, the t-test was used to determine the validity of the relationship between the constructs.   Results The hypotheses showed that the innovation intermediaries have a significant effect on understanding the ease of use of emerging technologies, perceived usefulness, willingness to adopt emerging technologies, legal support in the adoption of emerging technologies, security concerns in the adoption of emerging technologies, cost savings of emerging technologies in the automotive industry. …”
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Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…Abstract Objective To develop an automatic segmentation model to delineate the adnexal masses and construct a machine learning model to differentiate between low malignant risk and intermediate-high malignant risk of adnexal masses based on ovarian-adnexal reporting and data system (O-RADS). …”
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Periodically poled aluminum scandium nitride bulk acoustic wave resonators and filters for communications in the 6G era by Izhar, M. M. A. Fiagbenu, S. Yao, X. Du, P. Musavigharavi, Y. Deng, J. Leathersich, C. Moe, A. Kochhar, E. A. Stach, R. Vetury, R. H. Olsson

“…In this work, we utilized 4-layer AlScN periodically poled piezoelectric films (P3F) to construct high-frequency (~17–18 GHz) resonators and filters. …”
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Rumen DNA virome and its relationship with feed efficiency in dairy cows by Xiaohan Liu, Yifan Tang, Hongyi Chen, Jian-Xin Liu, Hui-Zeng Sun

“…Conclusions This study constructed a comprehensive rumen DNA virome profile for Holstein dairy cows, elucidating the structural and functional complexity of rumen viruses, the roles of AMGs, and vOTU-hMAG linkages. …”
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Probing Quantum Telecloning on Superconducting Quantum Processors by Elijah Pelofske, Andreas Bartschi, Stephan Eidenbenz, Bryan Garcia, Boris Kiefer

“…Quantum telecloning allows approximate copies of quantum information to be constructed by separate parties, using the classical results of a Bell measurement made on a prepared quantum telecloning state. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…The relationship between NTN1 and tumor heterogeneity, stemness, DNA methyltransferases, and MMR genes was also examined. Lastly, we constructed a nomogram based on NTN1 in SKCM and investigated its association with drug sensitivity. …”
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Prognostic evaluation of non-muscle invasive bladder cancer with P-CRP and its nomogram by Junyun Wu, Zhixuan Deng, Xu Lei, Zhiyao Xu, Chenxi Tan, Yunqiao Tang, Xi Sheng, Ning Yang

“…PurposeTo investigate the impact of the product of preoperative platelet count and C-reactive protein (P-CRP) on the postoperative prognosis of patients with non-muscle invasive bladder cancer (NMIBC), and to construct a Nomogram to predict the recurrence-free survival (RFS) of NMIBC patients based on pathological data.MethodsA retrospective analysis was conducted on the clinical data of 164 NMIBC patients who underwent transurethral resection of bladder tumors (TURBT) at the Second Affiliated Hospital of University of South China from January 2013 to December 2019. …”
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Through each other's eyes: initial results and protocol for the co-design of an observational measure of adolescent-parent interaction using first-person perspective by Nicky Wright, Rebecca M. Pearson, Rebecca M. Pearson, Danielle Crook, Danielle Crook, Alice Bond, Tom Jewell, Tom Jewell

“…“Trust” and “understanding” were most frequently reported as important adolescent-parent relationship constructs.ConclusionsThis work represents the first attempt to truly co-design a method to assess parenting in adolescence. …”
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