Paeoniflorin alleviates sepsis-associated acute kidney injury in mice by inhibiting aerobic glycolysis through the β-catenin/c-Myc pathway by GONG Yu, LEI Jiao, ZHANG Ming

“…Methods‍　‍Mouse SA-AKI model was constructed by intraperitoneal injection of 15 mg/kg LPS. …”
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Evaluation of change in emergency care knowledge and skills among front-line healthcare providers in Ukraine with the Basic Emergency Care course: a pretest/post-test study by Sean M Kivlehan, Amy Allen, Olha Viun, Dmitry A Makarov, Daniel Schnorr, Sonny Patel, Sergii A Ryzhenko, Phuong Pham, Timothy B Erickson

“…The most common positive feedback themes were high-quality teaching and useful skill sessions. The most common constructive feedback themes were translation challenges and request for additional skill session time.Conclusions This first implementation of the WHO-ICRC BEC course for front-line healthcare providers in Ukraine was successful and well received by participants. …”
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Evaluation of highway debris flow hazard based on geomorphic evolution theory coupled with material response rate by Na He, Ruze Han, Guisheng Hu, Zhiquan Yang, Linjuan Xu, Filip Gurkalo

“…The four debris flow gullies constructed during the upgrading project in Yajiang County, stretching from the west of the city to the Shearer Bay section, were analyzed via examples. …”
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The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

“…Methods and results Common DEGs were identified, and a PPI network was constructed using the STRING database and Cytoscape software to identify hub genes. …”
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Exploring the gender difference in type 2 diabetes incidence in a Swiss cohort using latent class analysis: an intersectional approach by Julien Vaucher, Michael Amiguet, Carole Clair, Joelle Schwarz, Jeanne Marie Barbier, Aurélie M Lasserre

“…The aim of this study was to highlight the intersectional social position of the participants and disentangle its role from administrative sex in predicting the development of type 2 diabetes.Methods Using CoLaus|PsyCoLaus study, a Swiss single-centre prospective cohort initiated in 2003 and including 6733 participants (age 35–75 years; 54% women) at baseline, we conducted latent class analyses using gender-related variables (eg, risk-taking behaviours, gender roles represented by employment status, etc) and socioeconomic determinants at baseline (2003–2006) to construct intersectional classes and we tested their association with the development of type 2 diabetes at follow-up (2018–2021).Results Of the 6733 participants enrolled at baseline, 3409 were included in our analyses (50.6%). …”
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Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006. by Gamji Rabiu Abu-Ba'are, Osman Wumpini Shamrock, Darcey Rodriguez, George Rudolph Kofi Agbemedu, LaRon E Nelson

“…The team will review and discuss codes to create a cohesive set of codes that will be instrumental in identifying knowledge gaps and constructing themes that summarize the data. The proposed systematic review will be among the pioneering efforts to rigorously assess global data on HIV prevention and care, with a specific focus on adolescents 10-19 years. …”
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Prediction of successful weaning from renal replacement therapy in critically ill patients based on machine learning by Qiqiang Liang, Xin Xu, Shuo Ding, Jin Wu, Man Huang

“…Multiple logistic regression (MLR) and machine learning algorithms were adopted to construct the prediction models.Results A total of 976 patients were included, with 349 patients successfully weaned off RRT. …”
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Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis by Hua Guo, Jinyang Gao, Liping Gong, Yanqing Wang

“…Heterogeneity in dependent instruments (HEIDI) test and colocalization analyses were performed to identify shared causal variants, and multi-omics integration was employed to construct potential regulatory pathways. Results Our analyses identified significant causal associations between DNA methylation, gene expression, protein abundance, and psoriasis risk. …”
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Don’t move a mussel: The role of key environmental drivers and management scale in assessing spatial variation in dreissenid spread risk in the Missouri River basin by Joseph Raymond, Lucas S. Bair, Timothy D. Counihan, Wesley M. Daniel, Sofie Duntugan, Matthew E. Neilson, Michael Springborn

“…., areas with naturally unsuitable water quality for dreissenids. To this end, we construct a composite relative risk index (CRR) for watersheds within the Missouri River Basin, a region in the United States on the front line of dreissenid spread. …”
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Immune gene features and prognosis in colorectal cancer: insights from ssGSEA typing by Anwen Huang, Jinxiu Wu, Jiakuan Wang, Chengwen Jiao, Yunfei Yang, Huaiwen Xiao, Li Yao

“…Subsequently, a prognostic risk model of CRC was constructed based on 12 prognostic genes, and the accuracy and reliability of the model prediction were verified. …”
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Genome-wide microsatellite characterization and their marker development and transferability in Broussonetia Species by Xiaowen Jia, Hanyu Li, Ying Han, Lu Wang, Chanjuan Lai, Xi Liu, Pan Li, Zupei Lei, Yonghua Zhang

“…Sequencing of their genomes allowed us to develop genomic markers (e.g. simple sequence repeats (SSRs)) and construct a high-density physical map. Results A total of 369,557, 332,627, and 276,245 SSRs were identified in 13 high-quality assembled pseudochromosomes and their unassembled scaffolds for B. papyrifera, B. monoica, and B. kaempferi, respectively. …”
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Attitudes of German General Practitioners Toward eHealth Apps for Dementia Risk Reduction: Qualitative Interview Study by Adrian Schultz, Melanie Luppa, Markus Bleckwenn, Steffi G Riedel-Heller, Andrea Zuelke

“…Data were fully transcribed and analyzed using a process model of qualitative content analysis with codes and categories being constructed inductively and deductively. …”
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Analgesia and sedation strategies in neonates undergoing whole-body therapeutic hypothermia: A scoping review. by Mahima Joshi, Javed Muneer, Lawrence Mbuagbaw, Ipsita Goswami

“…<h4>Conclusions</h4>No multidimensional pain scale has been tested for reliability and construct validity in hypothermic encephalopathic neonates. …”
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State Judgement Model of the Coal and Rock Medium and Its Engineering Application by Chuanqi Zhu, Lei Wang, Xiangang Han

“…Then, based on the variation law of the medium state index, the coal and rock mass medium state judgement model was constructed. This model was applied to judge the coal mass medium state. …”
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EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury by Shuangfei Ni, Bo Yang, Lei Xia, Huafeng Zhang

“…We used lipopolysaccharide (LPS) to induce inflammation of microglia, and we constructed the ASCI animal model. qRT-PCR detected the relative expression levels of EZH2, HIF-1α, miR-146a-5p, IL-6, TNF-α, IL-17, PKM2, GLUT1, and HK2 in cells and tissues. …”
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Risk prediction models for dysphagia after radiotherapy among patients with head and neck cancer: a systematic review and meta-analysis by You Pu, Jin Yang, Lian Shui, Qianlong Tang, Xianqin Zhang, Guangguo Liu

“…Of these models, most were constructed based on logistic regression, while only two studies used machine learning methods. …”
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Achievements and prospects of applying high-throughput sequencing techniques to potato genetics and breeding by I. V. Bykova, N. A. Shmakov, D. A. Afonnikov, A. V. Kochetov, E. K. Khlestkina

“…The Potato Genome Sequencing Consortium activities included not only constructing genome libraries, sequencing, assembling and annotation of the genome, but also genome sequence-based investigations uncovering features of potato genome evolution, SNP identification, analysis of genes and gene networks regulating resistance to phytopathogens and technological characteristics. …”
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INTRA-REGIONAL DIFFERENTIATION OF ENTREPRENEURSHIP OF MUNICIPALITIES OF THE ŚWIĘTOKRZYSKIE VOIVODESHIP IN TERMS OF SUSTAINABLE DEVELOPMENT IN 2010 AND 2020 by Paweł Dziekański, Łukasz Popławski, Fabio Fragomeni

“…Synthetic measures were constructed using the Technique for Order Preference by Similarity to an Ideal Solution method. …”
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Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis by Shuai Ma, Peifei Peng, Zhihao Duan, Yifeng Fan, Xinzhi Li

“…Furthermore, the upstream shared miRNA was predicted, and a miRNA–genes network was constructed. Candidate drugs were also analyzed and predicted. …”
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Antimicrobial use in animal farms in Egypt: rates, patterns, and determinants by Nada ElSayed, Amira Amine, Laila El-Attar, Mohamed E. K. Amin

“…Farm personnel’s AMU behavior was associated with the TRA constructs: perceived benefits of antimicrobials (attitude) and perceived AMU behavior in other farms (subjective norm). …”
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