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15001
Machine learning identification of a novel vasculogenic mimicry-related signature and FOXM1’s role in promoting vasculogenic mimicry in clear cell renal cell carcinoma
Published 2025-03-01“…Conclusion: This study constructed a VM-related signature and revealed that FOXM1 promotes VM formation in renal cell carcinoma through the PYCR1-PI3K/AKT/mTOR signaling axis, serving as a prognostic indicator and potential therapeutic target.…”
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15002
Enhanced Electrochemical Performance of Dual-Ion Batteries with T-Nb<sub>2</sub>O<sub>5</sub>/Nitrogen-Doped Three-Dimensional Porous Carbon Composites
Published 2025-01-01“…Herein, a nitrogen-doped three-dimensional porous carbon (RMF) was prepared for loading niobium pentoxide to construct a composite system with excellent electrochemical performance. …”
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15003
Identification and Pathogenicity of <i>Fusarium</i> Species from Herbaceous Plants on Grassland in Qiaojia County, China
Published 2025-01-01“…Through morphological means and based on ITS, <i>RPB2</i>, and <i>TEF-1</i> gene sequences, we compared and constructed polygenic phylogenetic trees to classify and identify the <i>Fusarium</i> species. …”
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15004
Drug Efficacy Recommendation System of Glioblastoma (GBM) Using Deep Learning
Published 2025-01-01“…A drug efficacy recommendation system was constructed using a deep learning method that combines gene expression, drug Simplified Molecular Input Line Entry System (SMILES), and inhibitory concentration features. …”
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15005
Measurement properties of the Traumatic Brain Injury Quality of Life (TBI-QoL) and Spinal Cord Injury Quality of Life (SCI-QoL) measurement systems: a systematic review
Published 2025-01-01“…Both measurement systems have sufficient content validity, structural validity, internal consistency and construct validity across nearly all domains (GRADE: high). …”
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15006
Evaluation of nitrous oxide reduction in solid carbon source-driven counter-diffusional biofilm denitrification system
Published 2025-05-01“…In this work, a fixed bed bioreactor driven by polycaprolactone (PCL) was constructed and operated over 180 days, achieving 97 %-99 % of total nitrogen (TN) removal efficiency. …”
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15007
The preoperative neutrophil‐to‐lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving r...
Published 2019-03-01“…A total of 994 subjects were retrospectively enrolled, and the histological specimens of 210 patients were retrieved for constructing a tissue microarray. Immunohistochemistry was then performed to assess the expression of AR, ERG, PTEN, p‐AKT, Bcl‐2, Beclin‐1, Ki‐67, CD3, CD4, CD8, IFN‐γ and TNF‐α. …”
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15008
The Effect of FOXA3 Overexpression on Hepatocyte Differentiation and Liver Regeneration in a Fah cKO Mouse ModelSummary
Published 2025-01-01“…Moreover, a Fah conditional knockout mouse model (Fah cKO mice) was constructed using the CRISPR-Cas9 method and treated with RF3 spheroids for transplantation. …”
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15009
Online tools to predict individualised survival for primary oesophageal cancer patients with and without pathological complete response after neoadjuvant therapy followed by oesoph...
Published 2024-07-01“…Two distinct multivariable Cox models of overall survival (OS) were constructed for pCR and non-pCR patients, respectively, and were presented using web-based dynamic nomograms (graphical representation of predicted OS based on the clinical characteristics that a patient could input into the website). …”
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15010
A Large Ship Detection Method Based on Component Model in SAR Images
Published 2025-01-01“…Experiments on the large ship component model dataset constructed for this article demonstrate significant improvements in the proposed algorithm over the preoptimized YOLOv8. …”
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15011
A nomogram for predicting mortality risk in geriatric patients with hip fractures complicated by pneumonia: A multicenter study
Published 2025-02-01“…Multiple logistic regression was then used to identify independent risk factors for inpatient mortality in the P group and a nomogram was constructed to predict inpatient mortality. The predictive performance of the nomogram was assessed using receiver operating characteristic curves, decision curve analysis, and calibration curves. …”
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15012
Experimental analysis of micro-cavity influence on the effective solar absorptance of white sand curtain on porous obstructions of particle heating receivers
Published 2025-02-01“…A high-flux module (HFM) was devised and constructed to experimentally assess ESA, comprising a particle-handling unit, a primary concentrator, and a secondary concentrator. …”
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15013
Development of the cultural tailoring score (CTS): a scoring instrument to assess cultural tailoring of health messaging
Published 2025-12-01“…It is based on research demonstrating the importance of: (1) Levels of engagement of the intended audience in the production, (2) use of understandable and culturally meaningful language, incorporation of (3) surface cultural cues and (4) deeper cultural constructs, (5) presence of a narrative to bind the information and cultural elements into a relatable story, and (6) factors associated with concrete psychological construal level (“now,” “here,” “you”).Methods We document a trial of the cultural tailoring score conducted by graduate students identifying as Filipino, Haitian, or Hispanic/Latinx reviewing 17 ads promoting COVID-19 vaccine that had been pretested during the pandemic for perceived effectiveness with convenience samples of these same ethnic groups.Results We achieved a combined Spearman’s Rank Correlation rho of 0.45 between the cultural tailoring score and perceived effectiveness ranking of all 17 ads (individual cultural groupings range from Spearman’s rho 0.45 to 0.90), suggesting that cultural components were moderately to strongly associated with perceived effectiveness. …”
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15014
The Women in ORTHopaedics Program Offers Early Exposure to Orthopaedic Surgery for Young Women. A Pre- and Post-Event Survey Comparison
Published 2025-02-01“…Conclusions: Findings indicate that WORTH played a constructive role in guiding young women toward trajectories beyond secondary education. …”
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15015
Optimization and potential assessment of CO2 geological storage caprock in the saline aquifers of the Qingjiang Basin, middle and lower reaches of the Yangtze River
Published 2025-04-01“…Based on these findings, a hierarchical structure model was constructed, including three evaluation index layers and 21 evaluation indicators. …”
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15016
Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
Published 2022-06-01“…The SRs included 205 outcomes and involved 138 995 participants from 1402 RCTs. We constructed 77 evidence matrices, including 120 SRs and their included RCTs in the Epistemonikos database. …”
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15017
Unleashing the potential of a low CpG Passer transposon for superior CAR-T cell therapy
Published 2025-02-01“…BALB/c mice and M-NSG mice were used to evaluate the inflammatory response and efficacy of LCG CAR-T in vivo, with TIL grouping detected via immunohistochemistry.ResultsIn this study, we modified the newly discovered Passer (JL) transposon to construct a low-CpG content transposon for CAR-T cell (LCG CAR-T cell) preparation. …”
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15018
Genetic Mapping for Seed Aging Tolerance Under Multiple Environments in Sweet Corn
Published 2025-01-01“…Utilizing SNP arrays, genotypes were identified, and a genetic linkage map was constructed. Composite interval mapping was employed to detect quantitative trait loci (QTLs) associated with five seed vigor traits, namely the seedling fresh weight (SFW), germination potential (GP), germination rate (GR), germination index (GI), and vigor index (VI), at three days after artificial aging treatment. …”
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15019
Identifying the healthy places to live in Australia with a new environmental quality health index
Published 2025-01-01“…Exposure-mortality relationships were estimated using a spatial age-period-cohort model, and EQHIs (scored 0–100, with higher values indicating better conditions) were constructed. Validation was performed using K-fold cross-validation and spatial regression models. …”
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15020
Global, regional, and national burden of early-onset colorectal cancer from 1990 to 2021: a systematic analysis based on the global burden of disease study 2021
Published 2025-01-01“…The relationship between socio-demographic index (SDI) and disease burden was assessed by the concentration index of inequality. In addition, we constructed a Bayesian age-period-cohort model to predict the burden of EOCRC worldwide from 2022 to 2030. …”
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