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Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases
Published 2020-12-01“…Estimation of an optimal corticosteroid (CS, prednisone) dosage for the remission induction in patients with ulcerative colitis (UC) and Crohn’s disease (CD) based on the construction of a dose-effect relationship during the first and second courses of therapy.Materials and methods. …”
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Exploring the inhibitory effect and mechanism of isorhamnetin therapy on oral squamous cell carcinoma based on network pharmacology and molecular docking
Published 2025-01-01“…Methods The key targets were obtained by constructing the PPI protein interaction network based on the common intersection targets of Iso-OSCC. …”
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7325
Development of a problem-oriented index system for evaluating the integration of medical treatment and prevention at county level: a Delphi study based on the rainbow model
Published 2024-12-01“…ObjectiveTo construct an evaluation index system in accordance with the practical implementation of county-level medical treatment and prevention integration in China, and to provide guiding principles and evaluation tools for its scientific development. …”
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7326
An endoscopic ultrasound-based interpretable deep learning model and nomogram for distinguishing pancreatic neuroendocrine tumors from pancreatic cancer
Published 2025-01-01“…The optimal DL model was identified and used to establish a clinical signature, which subsequently informed the construction and evaluation of a nomogram. Gradient-weighted Class Activation Mapping (Grad-CAM) and Shapley Additive Explanations (SHAP) were implemented to interpret and visualize the model outputs. …”
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7327
Climate-change impacts on distribution, habitats, sustainability and cultivation planning of two economically and ecologically important forest trees (China fir and Masson pine) in...
Published 2025-01-01“…Unraveling the influences of ANCC on forest trees is essential for understanding the response of forests to climate change and devising future strategies for forestry construction and production. In this study, multi-species distribution models and ArcGIS were utilized to identify priority planting and tending areas and simulate the spatiotemporal variation of habitat suitability for two economically and ecologically important forest trees: China fir (Cunninghamia lanceolata (Lamb.) …”
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An Investigation of the Capabilities of Resin Tire Carbon Black “N-330” as a Waste Binder in Asphalt Concrete Mixtures
Published 2025-01-01“…With the increasing demand for environmentally friendly construction materials, this research aims to assess the feasibility of incorporating resin tire carbon black N-330 “RTCB N-330” into asphalt as a full replacement for conventional binders. …”
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7330
Targeted genome modifcation in protoplasts of a highly regenerable Siberian barley cultivar using RNA-guided Cas9 endonuclease
Published 2019-01-01“…Site-directed plant genome modifcation by this technology involves the construction of Cas endonuclease- and guide-RNA-encoding vectors, delivery of the plasmid DNA into plant cells, processing of the chosen genomic target site by the corresponding gene products and regeneration of plants from modifed cells. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial
Published 2025-01-01“…The primary efficacy indicator will be the change in NRS score after four weeks of treatment, with secondary outcomes including WOMAC, STAI, and safety assessments. fMRI observations will employ independent component analysis, brain network construction, and functional connectivity, complemented by Pearson correlation analysis to explore the relationship between brain responses and clinical improvements.Conclusion: This study will initially uncover how acupuncture intervention for chronic KOA pain centrally regulates and exerts therapeutic effects through the modulation of abnormal brain network functional connectivity patterns, with a demonstrated long-term effect.Ethics and Dissemination: This study has been approved by the ethics committee of Shandong University of Traditional Chinese Medicine Affiliated Hospital ((2024) Lunshen No. (028) - KY).Clinical Trial Registration: This study has been approved by registered in the Chinese Clinical Trial Registry (ChiCTR2400083695).Keywords: acupuncture, knee osteoarthritis, neuroimaging, RCT, protocol…”
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7332
Differential controls on CO2 and CH4 emissions from the free-flowing Neretva River, Bosnia and Herzegovina
Published 2023-12-01“…In contrast, CO2 evasion was more variable in time and equally dependent on CO2 and gas exchange velocity. The construction of dams intended in this area would lead to reservoirs of slowly flowing or standing water with similar habitat conditions as the observed CH4-hotspot. …”
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7333
Cyclic surfaces accompanying non-ruled quadrics of rotation
Published 2023-09-01“…The geometric scheme of surface shaping is based on a construction that includes: a curvilinear axis of rotation and a one-parameter set of its normal planes; a generatrix whose points describe in normal planes circular trajectories centered on a curvilinear axis. …”
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7334
Comment faire une « sociologie des singes » et une « éthique » de l’expérimentation animale ?
Published 2014-01-01“…A noter qu’à l’appellation de « sociologie des études animale » nous pourrions préférer celui d’« anthropozoologie » ou encore « sociologie des singes » (pour Bruno Latour, Shirley Strum serait une « sociologue des singes », et les babouins qu’elle étudia, « des sociologues à fourrure ») car ce champ, en processus de construction, nous l’aurons compris, reste à être défini. …”
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Un port rural antique de fond d’estuaire à Blainville-sur-Orne (Calvados)
Published 2020-12-01“…Particular attention is paid to the description of the construction methods and the evolution of these architectural elements. …”
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7336
Dufulin Impacts Plant Defense Against Tomato Yellow Leaf Curl Virus Infecting Tomato
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7337
Multiscale study on the compressive performance of diverse solid waste backfill bodies
Published 2025-01-01“…The research findings can provide reference for the design and construction of solid waste backfill pipelines and trenches.…”
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A QUALITATIVE ANALYSIS OF THE INFLUENCE OF MANAGEMENT INFORMATION SYSTEMS ON ORGANIZATIONAL DECISION-MAKING PROCESSES
Published 2024-11-01“…Through a series of in-depth semi-structured interviews with key decision-makers across diverse sectors—such as technology, healthcare, retail, construction, and consulting—this study captures the nuanced perceptions and experiences of professionals who rely on MIS to navigate complex decision-making environments. …”
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7339
A Method for Quantifying Mung Bean Field Planting Layouts Using UAV Images and an Improved YOLOv8-obb Model
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Balancing on carbon storage and ecological security in urban areas: The case of Dongguan city, China
Published 2025-06-01“…However, by 2030, all scenarios show construction land expanding sharply across cultivated land and grassland, and carbon storage declines. …”
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