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  1. 22681

    Development of a machine learning model related to explore the association between heavy metal exposure and alveolar bone loss among US adults utilizing SHAP: a study based on NHAN... by Jiayi Chen

    Published 2025-02-01
    “…Logistic Regression (LR), Support Vector Machines (SVM), Random Forest (RF), K-Nearest Neighbor (KNN), Decision Tree (DT), and XGboost were used to construct the ML model. Accuracy, Area Under the Receiver Operating Characteristic Curve (AUC), Precision, Recall, and F1 score were used to select the optimal model for further analysis. …”
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  2. 22682
  3. 22683

    Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley by Yue Wang, Qian Hu, Youhua Yao, Yongmei Cui, Yixiong Bai, Likun An, Xin Li, Baojun Ding, Xiaohua Yao, Kunlun Wu

    Published 2025-01-01
    “…Based on the above research results, we constructed a Protein-Protein Interaction (PPI) network of barley leaf stripe resistance. …”
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  4. 22684
  5. 22685

    Optic Nerve Head Hemoglobin Levels in Glaucoma: A Structural and Functional Correlation Study by Janaina A. G. Rocha, Diego T. Dias, Maria Betânia C. Lemos, Fábio N. Kanadani, Augusto Paranhos, Carolina P. B. Gracitelli, Tiago S. Prata

    Published 2021-01-01
    “…Scatter plots were constructed, and regression analysis was used to investigate the correlations between GDF, average pRNFL thickness, and VF mean deviation (VFMD) index values. …”
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  6. 22686

    Unusual hypertrophic cardiomyopathy: case report of an early onset wild-type ATTR amyloidosis accompanied by a chromosomal duplication involving the MYH6 and MYH7 gene by Jassin Hamidi, Yvonne Hanel, Sven Dittmann, Wanda Maria Gerding, Huu Phuc Nguyen, Karin Klingel, Eric Schulze-Bahr

    Published 2025-02-01
    “…This highlights the extreme rarity of this condition, making it challenging to ascertain the extent to which a presumably mutated hybrid myosin gene construct or the TTR amyloid fibrils contribute to stiffness, tissue fibrosis, and cardiac dysfunction. …”
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  7. 22687

    The Effectiveness of Rapamycin Combined with Eltrombopag in Murine Models of Immune-Mediated Bone Marrow Failure by Shaoxue Ding, Xiaowei Liang, Tian Zhang, Rong Fu

    Published 2020-01-01
    “…In this study, an immune attack-mediated AA mouse model was constructed by total body irradiation (TBI) and allo-lymphocyte infusion. …”
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  8. 22688

    Analysis of the interaction mechanism between straw soil rotary tillage blade during rotary tillage process by Zhaojie Wang, Xiangyu Li, Junwei Li, Yuntao Qiu, Tianlong Gu, Hailong Wang

    Published 2025-01-01
    “…Based on EDEM software, we constructed a soil-rotary tillage cutter-straw interaction model, carried out straw-soil-rotary tillage cutter interaction mechanism analysis. …”
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  9. 22689

    The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice by Mengqi Xie, Zhongshun Huang, Yun Zhang, Yujie Gan, Huiying Li, Dan Li, Honglei Ding

    Published 2025-02-01
    “…Finally, lymphocyte proliferation after stimulation with corresponding proteins or crude extract of M. hyopneumoniae J strain was assessed.ResultsWe successfully constructed recombinant bacteria expressing rMhp170, rMhp274, and rMhp336. …”
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  10. 22690

    Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets by Huahua Li, Lingling Zou, Zhaowei Long, Junkun Zhan, Junkun Zhan

    Published 2025-01-01
    “…Machine learning models were constructed to classify T2DM subtypes based on metabolic signatures, and T-cell-monocyte interactions were explored to assess immune crosstalk. …”
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  11. 22691

    Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

    Published 2025-01-01
    “…ObjectiveTo investigate the protective effect of naringin on mitochondrial apoptosis in osteoarthritic (OA) chondrocytes by regulating lncRNA GAS5.MethodsIn vivo experiments, a rat OA model was constructed using the modified Hulth method and treated with naringin at 70 mg/kg by gavage for 8 weeks. …”
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  12. 22692

    Association between life's essential 8 and Parkinson's disease: a case–control study by Jiaxin Fan, Yanfeng Wang, Xingzhi Guo, Shuai Cao, Shuqin Zhan, Rui Li

    Published 2025-02-01
    “…Multivariate logistic regression models were constructed to explore the association between LE8 metrics and PD. …”
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  13. 22693

    Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

    Published 2025-01-01
    “…This study aimed to construct a nomogram based on systemic inflammation biomarkers and traditional prognostic factors to assess the risk of surgical site infection (SSI) after hip fracture in the elderly. …”
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  14. 22694

    The Value of Serum YKL-40 and TNF-α in the Diagnosis of Acute ST-Segment Elevation Myocardial Infarction by Caoyang Fang, Zhenfei Chen, Jing Zhang, Jianyuan Pan, Xiaoqin Jin, Mengsi Yang, Luyao Huang

    Published 2022-01-01
    “…Three diagnostic models were constructed: cTnI univariate model (model A), combined serum YKL-40 and TNF-α model other than cTnI (model B), and combined cTnI and serum YKL-40 and TNF-α model (model C). …”
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  15. 22695

    Resilience of Fishery Economy in Fujian Coastal Areas from the Perspective of Institutional Evolution by Leng Yun, Wei Suqiong, You Xiaojun, Ren Zhihuang

    Published 2025-01-01
    “…This study considers the fishery industry in the coastal area of Fujian Province as an example, measures the resilience resistance of the fishery industry using output value and output, and constructs an analytical framework by combining the "Robustness-Resistance-Recovery" resilience assessment framework and the theory of institutional change to give explanations for the formation of the differences in fishery resilience. …”
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  16. 22696

    Examining the Leverage Effect, Dynamic Conditional Correlation, and Volatility Spillover Among Selected Indices of the Tehran Stock Exchange: Evidence from the ARMA-DCC-GJR-GARCH M... by Gholamhosein Golarzi, Seyed Ramin Abolfazli

    Published 2024-03-01
    “…MethodsIn this study, the ARMA (1,1) form was utilized to construct the mean model. Then, the GJR-GARCH model was used to check the leverage effects. …”
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  17. 22697

    Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction by Yize Sun, Yize Sun, Haibin Zhao, Zheyi Wang

    Published 2025-01-01
    “…All the targets were intersected to construct the Protein-Protein Interaction (PPI) network on Metascape platform and the herb-compound-target (HCT) network on Cytoscape, to identify the hub targets. …”
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  18. 22698

    Regional Ionospheric Parameter Estimation by Assimilating the LSTM Trained Results Into the SAMI2 Model by Jeong‐Heon Kim, Young‐Sil Kwak, Yong Ha Kim, Su‐In Moon, Se‐Heon Jeong, Jong Yeon Yun

    Published 2020-10-01
    “…Abstract This paper presents a study on the possibility of predicting the regional ionosphere at midlatitude by assimilating the predicted ionospheric parameters from a neural network (NN) model into the Sami2 is Another Model of the Ionosphere (SAMI2). The NN model was constructed from the data set of Jeju ionosonde (33.43°N, 126.30°E) for the period of 1 January 2011 to 31 December 2015 by using the long‐short term memory (LSTM) algorithm. …”
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  19. 22699

    Effect of <italic>Shaoyao Gancao</italic> Decoction on Inflammatory Injury of Posterior Cervical Muscle Based on miR-146a Regulation of NF-κB Signaling Pathway by Jincheng CHEN, Rong LIN, Yuanfang ZHANG, Jiquan DONG, Weilin LIU, Zheng JIANG, Shaoqing CHEN, Xiangbin WANG, Jian HE

    Published 2020-06-01
    “…Objective:To investigate the effect of <italic>Shaoyao Gancao</italic> decoction on the injury of rabbit cervical posterior myoinflammation and its possible mechanism from histology and molecular level, and provided experimental basis for the clinical application of <italic>Shaoyao Gancao</italic> decoction in the treatment of cervical spondylopathy.Methods:A total of thirty 6-month-old New Zealand white rabbits were randomly divided into high dose group, medium dose group, low dose group, model group and normal group, with 6 rabbits in each group. The model was constructed according to the cold and wet rabbit cervical spondylopathy model prepared by the research group. …”
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  20. 22700

    Urine proteomics defines an immune checkpoint-associated nephritis signature by Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong

    Published 2025-01-01
    “…Using statistical and machine learning methods, we constructed a novel urine biomarker signature—IL-5+Fas—that achieved an area under the curve of 0.94 for diagnosing ICI-AIN.By leveraging high-sensitivity proteomics, we developed a non-invasive strategy for diagnosing ICI-AIN. …”
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