The predicted value for venous thromboembolism based on a modified model of caprini combined with fasting blood glucose and D-dimer: a retrospective study by Ping Wang, Yusi Yang, Lin Zheng, Xiaotong Qi, Sheng Yan, Honglin Dong

“…In addition to Caprini and age, FBG and D-dimer may be important predictors of deep vein thrombosis in patients with LEF. Therefore, we constructed three models. caprini + D-dimer, caprini + FBG, and caprini + D-dimer + FBG. …”
Get full text

The Association of HOTAIR with the Diagnosis and Prognosis of Gastric Cancer and Its Effect on the Proliferation of Gastric Cancer Cells by Zhiying Xu, Hui Chen, Bin Yang, Xiangfeng Liu, Xiaoli Zhou, Hongfang Kong

“…Furthermore, a receiver operating characteristic (ROC) curve was constructed. Additionally, the correlation between this lncRNA and overall survival (OS) was analyzed. …”
Get full text

Correlation and predictive value of novel anthropometric indicators with adult sarcopenia and sarcopenia obesity by Xue Wu, Ziang Chen, Yuanhui Zhao, Hong Ren

“…Utilizing the diagnostic criteria established by the American Foundation for the National Institutes of Health (FNIH), anthropometric measurement data were extracted to construct composite indices. These indices were then cross-referenced with diagnostic assessments from dual-energy X-ray absorptiometry and bioelectrical impedance analysis to examine the correlations between various metrics and the incidence of diseases. …”
Get full text

Self-assessment of didactic performance of psychology and education professors in Mexico and Peru by Aldo Bazán-Ramírez, Walter Capa-Luque, Roberto Chávez-Nava, Mónica C. Dávila-Navarro, Homero Ango-Aguilar, Edmundo Hervias-Guerra, Catalina Bello-Vidal

“…As for the evidence of validity based on the internal structure of the construct, satisfactory results were found with the confirmatory factor analysis strategy for a multidimensional model of seven oblique factors (CFI = 0.99, TLI = 0.98, RMSEA = 0.05, SRMR = 0.06) and a second-order factor model made up of two general factors and seven specific first-order factors (CFI = 0.98, TLI = 0.98, RMSEA = 0.06, SRMR = 0.07). …”
Get full text

Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain by Chen Y, Tang G, Lu J, Tang S, Xiong X, Chen C, Pei L, Shi J

“…In vitro experiment, the astrocyte model was constructed by Vincristine, and si-C/EBP-β was regulated before VCR administration. …”
Get full text

The Efficacy of Conversational AI in Rectifying the Theory-of-Mind and Autonomy Biases: Comparative Analysis by Marcin Rządeczka, Anna Sterna, Julia Stolińska, Paulina Kaczyńska, Marcin Moskalewicz

“…MethodsThis study used constructed case scenarios simulating typical user-bot interactions to examine how effectively chatbots address selected cognitive biases. …”
Get full text

An intraoperative nomogram for predicting secondary margin positivity in breast conserving surgery utilizing frozen section analysis by Cheng Li, Yan Jiang, Xumiao Wu, Yong Luo, Qi Li

“…LASSO identified six variables to construct the model and corresponding nomogram. The model showed good discrimination (mean area under the curve (AUC) values of 0.79 in the training set and 0.83 in the testing set), calibration (Hosmer-Lemeshow test results (p-values 0.214 in the training set, 0.167 in testing set)) and clinical utility. …”
Get full text

Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…We remark that in various time scale domains $$\mathbb {N}_{\ell }$$ , the investigated discrete formulations will be $$\rho ^{2}$$ -nonincreasing or $$\rho ^{2}$$ -nondecreasing by examining $$\rho$$ -monotonicity formulations and the basic properties of the suggested operator. Algorithms are constructed in the discrete generalized Mittag–Leffler (GML) kernel for mathematical simulations, emphasizing the effects of the infection resulting from multiple factors. …”
Get full text

Development of the children's primitive reflex integration assessment scale by Meng Wang, Jing Yu, Hongyao Li, Chongran Zhao, Yichao Li, Xinyue Yang

“…For formal testing data, Cronbach's α assessed the reliability of the scale, while fit indices such as chi-square value/degrees of freedom (χ2/df), Root Mean Square Error of Approximation (RMSEA), and Comparative Fit Index (CFI), along with tests of construct validity, evaluated the scale's validity.ResultsOverall, 555 participants were selected, 234 children with a mean age of 7.59 ± 0.71 years participated in the pilot testing, while 321 children with a mean age of 7.73 ± 0.71 years participated in the formal testing. …”
Get full text

Identification of Five m6A-Related lncRNA Genes as Prognostic Markers for Endometrial Cancer Based on TCGA Database by Li Shan, Ye Lu, Cheng-Cheng Xiang, Xiaoli Zhu, Er-Dong Zuo, Xu Cheng

“…The risk-based model constructed from the five key m6A-related lncRNAs was implicated in immune cell infiltration and can potentially be an accurate prognosticator for UCEC.…”
Get full text

Mechanism of Action of Decitabine in the Treatment of Acute Myeloid Leukemia by Regulating LINC00599 by Fan Du, Ting Jin, Li Wang

“…The regulatory relationship between miR-135a-5p and LINC00599 was verified by constructing miR-135a-5p mimics, miR-135a-5p inhibit, wild type LINC00599 3′-untranslated region (UTR), and mutant LINC00599 3′-UTR. …”
Get full text

Echoes of Strain: A Two-Year Longitudinal Study on the Impact of China’s Zero-COVID Policy on College Students’ Insomnia and Depressive Symptoms by Wang S, Zou X, Tang Q, Zhang L, Liu X, Liu G, Tao Y

“…Three contemporaneous symptom networks and two cross-lagged panel networks were constructed.Results: In the current sample, the prevalence of clinically significant depressive symptoms was 6.1%, 8.9%, and 7.7% during the first, second, and third waves, respectively. …”
Get full text

Measures of social connectedness in adult populations: a systematic review by Ruth Plackett, Joe Hulin, Clara Mukuria, Mark Clowes, Sheena E. Ramsay, Liam Spencer, Emma A. Adams, Jennifer Dykxhoorn, Kate Walters, David P. J. Osborn, Victoria Zamperoni, Oliver Jones, Scott Weich

“…Psychometric evidence was extracted relating to six general domains: conceptual model, content validity, reliability, construct validity, scoring and interpretability, and respondent burden and presentation. …”
Get full text

Ethical education: Ways of moral consciousness development (understanding experience through Tyumen ethical and philosophical tradition) by E. N. Yarkova, A. G. Ivanov, Ya. V. Maltsev

“…is of great concern to both theorists, who construct various models of ethical education, and, practitioners, who implement these models in life.A serious source of knowledge concerning the methodology of ethical education is the concept of the individual moral consciousness development, created by well-known ethicists A. …”
Get full text

Effect of Swimming on Gut Microbiota and Inflammation in Colorectal Cancer Cells Transplanted Mice by LI Jiapeng, XIE Qiurong, WEN Ying, CHEN Haichun, PENG Jun, SHEN Aling

“…ObjectiveTo investigate the effects of swimming on the growth of colorectal cancer (CRC) transplanted tumor in mice, and to explore its regulation mechanism from the perspective of gut microbiota and inflammation.MethodsThe CT-26 bearing mouse model was constructed and the experiment mice were randomly divided into model and swimming groups. …”
Get full text

To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation by Sha Li, Jingshan Chen, Wenjing Zhou, Yonglan Liu, Di Zhang, Qian Yang, Yuerong Feng, Chunli Cha, Li Li, Guoyong He, Jun Li

“…Finally, immunoinfiltrative analysis was performed, and the transcription factor (TF)–microRNA (miRNA)–mRNA regulatory network and the drug–gene interaction network were constructed. There were 2633 DN-DEGs between the DN and control samples and 515 PM-DEGs between the high and low PMRG score groups. …”
Get full text

Comprehensive analysis of clinicopathologic and prognostic features in locally advanced thyroid papillary cancer by Liang Jiwang, Ye Dongman, Fang Fengqin, Zhao Yuejiao

“…This study was to investigate the clinicopathologic features of LAPTC and the risk factors that affect its postoperative recurrence. We aimed to construct a nomogram to predict Recurrence-Free Survival (RFS) in LAPTC. …”
Get full text

A within-person investigation of recovery identity following substance use disorder: examining the impact of recovery-focused social contexts by Joseph H. Lancaster, Hannah B. Apsley, Timothy R. Brick, Timothy R. Brick, H. Harrington Cleveland

“…Until now, no studies have investigated recovery identity as a dynamic construct, although recent findings suggest it fluctuates from one day to the next. …”
Get full text

C5a/C5aR regulates Th1/Th2 imbalance in sepsis-associated lung injury by promoting neutrophil activation to increase PAD4 expression by Zhenbing Lu, Ling Zhu, Changlin Yi, Bi Su, Renying Wang

“…An LPS-induced septic lung injury mouse model was constructed, with HE and PAS stains evaluating lung damage. …”
Get full text

Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude by Xiaozhen Liu, He Ding, Xiaoxue Zhang, Na Ta, Jinmei Zhao, Qian Zhang, Huiyun Liu, Mengjiao Sun, Xiaoqing Zhang

“…Moreover, a Gangba sheep gastrointestinal microbial genomic catalogue was constructed for the first time, including 1146 metagenome-assembled genomes (MAGs) with completeness > 50% and contamination < 10%, among which, 504 bacterial and 15 archaeal MAGs were of high quality with completeness > 80% and contamination < 10%. …”
Get full text