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21861
Establishment of a rapid method for the detection of Brucella canis based on recombinase-mediated thermostable nucleic acid amplification technology
Published 2025-01-01“…Primers and fluorescent probes were designed and synthesized, and recombinant plasmids were constructed as standards. The RAA assay was optimized by screening primers and establishing a fluorescent reaction system. …”
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21862
Ultrasound radiomics-based logistic regression model for fibrotic NASH
Published 2025-02-01“…Radiomics characteristics were derived from two-dimensional liver ultrasound images of the rats, and a radiomics model was constructed, with rad-scores calculated accordingly. …”
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21863
Rebound Mechanism and Control of the Hard Main Roof in the Deep Mining Roadway in Huainan Mining Area
Published 2021-01-01“…To control the stability of the top beam and simplify the supporting reaction to limit the deformation of the slope angle, RC and RD are used to construct the statically indeterminate beam. By adding an anchor cable and advance self-moving support to the roadway side angle, the problem of difficult control of the surrounding rock with a large deformation of the side angle roof is solved, which provides a reference for roof control under similar conditions.…”
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21864
An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction
Published 2025-01-01“…Despite its effectiveness, DE has a significant drawback as it relies on randomly selecting indices from the population of target vectors to construct donor vectors in search of optimal solutions. …”
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21865
A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins
Published 2025-02-01“…Based on a high-resolution 2.91 Å CP model that was constructed for the first time, this degradation process is likely driven by hydrophobic interactions between tCuinter-bCDs and CP residues MET1, VAL5, THR55, and THR58, along with hydrogen bonds formed with THR4, VAL5, GLY15, PRO57, and ALA59, thereby promoting degradation of adjacent peptide segments. …”
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21866
MRI-based deep learning and radiomics for predicting the efficacy of PD-1 inhibitor combined with induction chemotherapy in advanced nasopharyngeal carcinoma: A prospective cohort...
Published 2025-02-01“…Results: Twenty-one prediction models were constructed. The Tf_Radiomics+Resnet101 model, which combines radiomic features and DLFs, demonstrated the best performance. …”
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21867
Structure and dynamics analysis of brain functional hypernetworks based on the null models
Published 2025-01-01“…Specifically, first, based on the original brain functional hypernetwork, this article proposed the optimized hyper dK-series algorithm with hyperedges to construct null models that preserved the different node attributes and hyperedge attributes of the original brain functional hypernetwork, respectively. …”
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21868
Current status of public health awareness and roles within medical institutions in eastern China
Published 2025-01-01“…ObjectiveTo examine the current landscape of public health functions and the level of cognition among medical staff across various medical institutions in Jiangsu Province, ultimately aiming to provide a theoretical framework for constructing a hospital public health work model under the integrated medical and defense system.MethodsA mixed-methods approach involving questionnaires and semi-structured interviews was employed to assess the establishment and operational status of public health departments within medical institutions, staffing scenarios, comprehension of public health tasks, and the degree of emphasis placed on them.ResultsOur findings reveal that 70.6% of medical institutions possess standalone public health departments, with a median of 5 full-time public health personnel, predominantly from the nursing profession. …”
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21869
Impact of distress and anxiety due to COVID-19 on digital addictions in university students in the third wave period [version 2; peer review: 3 approved]
Published 2025-01-01“…The first model shows that the latent variables distress and anxiety due to COVID-19 have direct effects on digital addictions as a general construct (R2 = 22%). The second model shows that the exogenous latent variables (stress and anxiety) have direct effects of different magnitudes on each digital technology, so the variance explained on smartphone addiction was higher (R2 = 25%) with respect to internet (R2 = 19%) and video game addiction (R2 = 6%). …”
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21870
Targeting TCMR-associated cytokine genes for drug screening identifies PPARγ agonists as novel immunomodulatory agents in transplantation
Published 2025-01-01“…To evaluate the effectiveness of this gene set, a diagnostic predictive model was constructed using Lasso regression and multivariate logistic regression, with validation in independent datasets. …”
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21871
A machine learning-based model to predict POD24 in follicular lymphoma: a study by the Chinese workshop on follicular lymphoma
Published 2025-01-01“…XGBoost was utilized to construct the POD24-predicting model, which was internally validated in the validation set and externally validated in the GALLIUM cohort. …”
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21872
Risk factors analysis and prediction model establishment of acute kidney injury after heart valve replacement in patients with normal renal function
Published 2025-02-01“…Based on the results, a risk prediction model was developed, and traditional and dynamic nomograms were constructed. The risk prediction model was evaluated using receiver operating characteristic (ROC), calibration curve, and decision curve analysis (DCA).Results220 patients (36.2%) developed AKI after surgery. …”
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21873
Parent-implemented early intervention design for improving speech and language skills among Mandarin-speaking infants and toddlers with cleft lip and/or palate
Published 2025-01-01“…Second, according to the problem diagnosis, the logical model of parent–child interaction behavior change was constructed. Finally, the health outcomes were transformed into intervention goals at three levels (i.e., infants and toddlers with CL/P, parents and environment), and a set of early intervention programs were designed by integrating various intervention techniques.ResultsThe diagnosis of parent–child interaction problems showed that 40.91% of parents and children often use electronic media together; in parent–child interaction, 41.67% of parents presented ‘lack of waiting’, 29.55% overcorrected pronunciation errors. …”
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21874
Hydrate-Based Methane Storage in Biodegradable Hydrogels Absorbing Dilute Sodium P-Styrenesulfonate Solution
Published 2024-12-01“…In this work, a kind of eco-friendly hydrogel, polyvinyl alcohol-co-acrylic acid (PVA-co-PAA), was utilized to absorb dilute sodium p-styrenesulfonate (SS) solution, for constructing a hybrid reaction medium for methane hydrate formation. …”
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21875
Psychometric accuracy of the Dutch Child and Adolescent Trauma Screener
Published 2025-12-01“…A total of 587 children and adolescent, age 7–21, and 658 caregivers referred to mental health care services in Amsterdam was included in the study to examine psychometric properties. The construct was tested by confirmatory factor analysis (CFA). …”
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21876
Inhibition of Endothelial–Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats
Published 2025-01-01“…Methods: Our study was divided into two parts: in vivo and in vitro. We constructed a small interfering RNA (ACVR2A-siRNA) by silencing activin receptor type IIA (ACVR2A) and an adeno-associated virus (AAV-ACVR2A) containing a sequence that silenced ACVR2A. …”
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21877
Mapping a Magnetic Superstorm: March 1989 Geoelectric Hazards and Impacts on United States Power Systems
Published 2022-05-01“…For this, a 1‐min‐resolution sequence of geomagnetic field maps is constructed from magnetometer time series acquired at ground‐based observatories. …”
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21878
Spatiotemporal dynamics of soil organic carbon in desert region and its response to climate change: A case study of Heihe river
Published 2025-01-01“…However, the long-term response mechanisms of SOC density in desert regions to climate change remain unclear, increasing uncertainty in estimating the carbon sequestration potential of these ecosystems. This study aims to construct a comprehensive SOC database for the lower reaches of the Heihe River (HRL) and simulate the spatiotemporal distribution of SOC density within the 0 – 100 cm soil profile. …”
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21879
3D Point Cloud from Millimeter-wave Radar for Human Action Recognition: Dataset and Method
Published 2025-02-01“…For each 3D point cloud frame, PETer constructs a locally directed neighborhood graph through edge convolution to extract spatial geometric features effectively. …”
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21880
NCAPD3‐mediated AKT activation regulates prostate cancer progression
Published 2025-02-01“…A subcutaneous tumor xenograft model was constructed by injecting DU145‐Lv‐NCAPD3 cells and control cells into male BALB/c nude mice to confirm the result derived from in vitro assay. …”
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