Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

“…A prognostic model was constructed by incorporating the presence or absence of G-CSF expression along with clinicopathologic factors, which allowed for a more accurate prediction of poor prognosis. …”
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Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration by Gang Lei, Yanqiu Wang, Yan Yu, Zehan Li, Jiamin Lu, Xingyun Ge, Na Li, Ana Gloria Cuba Manduca, Jinhua Yu

“…The model of critical-sized defects in the calvarium of rats was constructed for exploring the in vivo efficiency of DIM on bone regeneration. …”
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Revealing joint evolutions and causal interactions in complex ecohydrological systems by a network-based framework by L. Wang, H. Gu, L. Liu, X. Liang, S. Chen, Y.-P. Xu

“…The former employs correlations, and the latter uses physically constrained causality analysis to construct network relationships. This framework is applied to the Yellow River basin, a region undergoing profound ecohydrological changes. …”
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Precision Adverse Drug Reactions Prediction with Heterogeneous Graph Neural Network by Yang Gao, Xiang Zhang, Zhongquan Sun, Payal Chandak, Jiajun Bu, Haishuai Wang

“…Specifically, a heterogeneous graph representation of patients is constructed, encompassing nodes that represent patients, diseases, drugs, and ADRs. …”
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Design and Optimization for Straw Treatment Device Using Discrete Element Method (DEM) by Shaochuan Li, Peisong Diao, Xianghao Li, Yongli Zhao, Hongda Zhao

“…In this study, the Discrete Element Method (DEM) was employed to construct models of compacted soil and hollow, flexible wheat straw, forming the foundation for a comprehensive interaction model between the tool, soil, and straw. …”
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Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction by Mohsen Moslem, Irina Eberle, Iuliia Weber, Reinhard Henschler, Tobias Cantz

“…We generated such iPSC-MSCs from fibroblasts and bone marrow MSCs utilizing two different reprogramming constructs. All such iPSC-MSCs exhibited the characteristics of normal bone marrow-derived (BM) MSCs. …”
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Fast Simulation of the Flow Field in a VAWT Wind Farm Using the Numerical Data Obtained by CFD Analysis for a Single Rotor by Yutaka Hara, Md. Shameem Moral, Aoi Ide, Yoshifumi Jodai

“…With the ultimate goal of determining the optimal layout of a wind farm (WF) for VAWTs, this study proposes a new method for quickly calculating the flow field and power output of a virtual WF consisting of two-dimensional (2-D) miniature VAWT rotors. This new method constructs a flow field in a WF by superposing 2-D velocity numerical data around an isolated single VAWT obtained through a computational fluid dynamics (CFD) analysis. …”
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Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality by Chris P Gale, Jonathan Weir-McCall, James H F Rudd, Mamas Mamas, Ramesh Nadarajah, Ben Gibbison, Louise Sun, Christian Philip Stickels, Houyuan Jiang, Kieran J Sharkey, Nick Holliman, Sara Lombardo, Lars Schewe, Matteo Sommacal, Katherine Cheema, Feryal Erhun

“…Objectives To provide estimates for how different treatment pathways for the management of severe aortic stenosis (AS) may affect National Health Service (NHS) England waiting list duration and associated mortality.Design We constructed a mathematical model of the excess waiting list and found the closed-form analytic solution to that model. …”
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Inhibitory Effect of PRMT5/MTA Inhibitor on MTAP‐Deficient Glioma May Be Influenced by Surrounding Normal Cells by Yunjie Wang, Xiaohui Sun, Runchen Ma, Xiaofan Zhang, Shengmin Ji, Zhaofeng Liu, Gangqiang Yang, Hongbo Wang, Peng Zhang, Jianzhao Zhang, Jingwei Tian

“…Then, in vivo and in vitro models of MTAP‐deficient gliomas coexisting with neurons or glial cells were constructed for evaluating the effectiveness of the anti‐tumor effects of MRTX1719 in this setting. …”
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AIEgen-self-assembled nanoparticles with anti-PD-L1 antibody functionalization realize enhanced synergistic photodynamic therapy and immunotherapy against malignant melanoma by Lu Li, Qing Xu, Xiuzhen Zhang, Yuan Jiang, La Zhang, Jiao Guo, Haichuan Liu, Bin Jiang, Shenglong Li, Qiling Peng, Ning Jiang, Jianwei Wang

“…The TBP@aPD-L1 NPs are constructed by functionalizing azide group-modified TBP-2 (TBP-N3) with anti-PD-L1 antibodies via the DBCO-S-S-PEG2000-COOH linker. …”
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Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum) by Yi Liu, Chao Bian, Ka Yan Ma, Yexin Yang, Yuanyuan Wang, Chao Liu, Guochang Ouyang, Meng Xu, Jinhui Sun, Changwei Shao, Jiehu Chen, Qiong Shi, Xidong Mu

“…Abstract Background Silver arowana (Osteoglossum bicirrhosum) is a basal fish species with sexual monomorphism, while its sex determination mechanism has been poorly understood, posing a significant challenge to its captive breeding efforts. Results We constructed two high-quality chromosome-level genome assemblies for both female and male silver arowana, with scaffold N50 values over 10 Mb. …”
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Simulation analysis of radiometer effect and outgassing based on molecular particle source perturbation by Wenyan Zhang, Zuolei Wang, Jian Min, Yi Wang, Jungang Lei, Yunpeng Li, Dongxue Xi

“…To this end, this paper conducts an in-depth decoupling analysis of the impacts of the radiometer effect and outgassing effect using a simulation method based on molecular particle source perturbation. By constructing a finite element simulation model that couples residual gas and temperature gradient fluctuations, we simulate molecular thermal motion based on fundamental theories such as Maxwell’s distribution function, the free path distribution law, and Knudsen’s adsorption layer hypothesis, in order to study the two manifestations of the radiometer effect and the outgassing. …”
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Limited data based kinetic modeling and optimization of propionic acid synthesis over supported Rh/C catalyst by László Balogh, Jenő Bódis, Botond Szilágyi, Ágnes Bárkányi, Attila Egedy

“…To make the process operate well, we apply the available measured data co construct a kinetic model, and use it to optimize the system subject to various goals. …”
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A breeding method for Ogura CMS restorer line independent of restorer source in Brassica napus by Xuesong Wang, Xingyu Liang, Rui Wang, Yuan Gao, Yun Li, Haoran Shi, Wanzhuo Gong, Saira Saleem, Qiong Zou, Lanrong Tao, Zeming Kang, Jin Yang, Qin Yu, Qiaobo Wu, Hailan Liu, Shaohong Fu

“…To further investigate and locate the restorer gene, the BSA method was employed to construct extreme mixed pools. As a result, the restorer gene was mapped to three positions: A09 chromosome 10.99–17.20 Mb, C03 chromosome 5.07–5.34 Mb, and C09 chromosome 18.78–36.60 Mb. …”
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Altered Brain Structural Networks in Patients with Brain Arteriovenous Malformations Located in Broca’s Area by Maogui Li, Pengjun Jiang, Jun Wu, Rui Guo, Xiaofeng Deng, Yong Cao, Shuo Wang

“…Weighted brain structural networks were constructed based on deterministic tractography. We compared the topological properties and network connectivity between patients and normal controls. …”
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Identification of Pseudoperonospora cubensis RxLR Effector Genes via Genome Sequencing by Rahel Dinsa Guta, Marc Semunyana, Saima Arif, Inyong Jeong, Sun Ha Kim, Jiyoung Min, Sang-Keun Oh

“…Subcellular localization of selected effectors was determined using GFP-tagged constructs. Functional characterization revealed that while most effectors did not induce a hypersensitive response (HR), a subset showed either weak or strong necrosis. …”
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A comprehensive overview of acupuncture therapy over the past 20 years: Machine learning-based bibliometric analysis by Chen Liu, Shuqing Liu, Yu Wang, Xinyi Xia, Yu Zhang, Huili Jiang, Tuya Bao, Xuehong Ma

“…A topic network was constructed by latent Dirichlet allocation (LDA) and the Louvain algorithm. …”
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Identification of the Bovine <i>CSN3</i> Core Promoter Region and the Relationships Between <i>CSN3</i> Promoter Polymorphisms and the <i>CSN3</i> A and B Alleles by Wenqing Li, Xiaoyang Wang, Xiuyang Xu, Pinhui Wu, Tong Fu, Liyang Zhang, Tengyun Gao

“…Therefore, a series of 5′-deleted promoter plasmids were constructed to define the core promoter of <i>CSN3</i>. …”
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KE-RSIC: Remote Sensing Image Captioning Based on Knowledge Embedding by Kangda Cheng, Erik Cambria, Jinlong Liu, Yushi Chen, Zhilu Wu

“…To acquire general knowledge, we construct a remote sensing knowledge graph and propose a general knowledge embedding method, enabling semantic correlations between entities and relationships in remote sensing knowledge graphs. …”
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FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils by Peiyuan Li, Wenbin Ji, Baotong Zhang, Haowen Jia, Jinmiao Wang, Zhaonan Sun, Yifan Wang, Weiwei Wang, Feng Qi

“…The effects of blocking FPR1 on neutrophil function as well as acute rejection were tested in vivo after constructing a mouse kidney transplant model. Results The proportion of neutrophils was higher in the AR group than in the non-rejection group, and FPR1 was identified as an important gene in the regulation of acute rejection in kidney transplantation by neutrophils. …”
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