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  1. 21241

    Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells by Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang

    Published 2025-01-01
    “…Subsequently, the protein Interaction Network (PPI), the annotation of gene ontology (GO) and the database of Kyoto Encyclopedia of Genes and Genomes (KEGG) were constructed for in-depth analysis. The results showed that CPV VP2 protein participated mainly in cell metabolism, cell biosynthesis, protein folding and various signal transduction processes. …”
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  2. 21242

    Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling by He-Fei Sun, Xin-Nan Wang, Ya-Nan Li, Lan-Lan Wang, Yue-Ying Li, Lian-Ju Ma, Xue-Mei Li

    Published 2025-02-01
    “…DElncRNAs and DEmRNAs were combined with miRNA database to construct ceRNA network. DEmRNAs in ceRNA network were mainly participated in carbohydrate metabolic process, peroxidase activity and phenylpropanoid biosynthesis. …”
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  3. 21243

    Supportive care needs of the family caregivers of urostomy patients: a qualitative study by Kaixia Gao, Shaoguo Zhang, Jie Liu, Fang Zhang, Na Liu, Jiyan Dong, Tingting Zhang, Junping Gao, Sufang Qin, Junhong An, Xiaojuan Han

    Published 2025-01-01
    “…Further, within these four themes, eight sub-themes were constructed using coders. The respondents reported that they felt equally under pressure as the urostomy patients they were caring for, although the medical staff appeared to be paying little attention to them. …”
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  4. 21244

    Feasibility of NepaDengue mobile application for dengue prevention and control: user and stakeholder perspectives in Nepal by Eggi Arguni, Anita Mahotra, Yuvraj Pokhrel, Tulsi Ram Thapa, Riris Ahmad Andono

    Published 2024-04-01
    “…Descriptive statistics were calculated, and a thematic analysis was conducted.Results The high acceptability mean rating scores reported based on the TAM construct indicate that the application is perceived as useful and easy to use and exhibits good functioning and gestural design. …”
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  5. 21245

    Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG1 antibodies by Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter

    Published 2024-12-01
    “…A panel of related monospecific and bispecific IgG1 antibodies was constructed and assessed for immunogenicity risk by comparison with benchmark antibodies with known low (Avastin and Herceptin) or high (bococizumab and ATR-107) clinical incidence of anti-drug antibodies. …”
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  6. 21246

    Development of an indicator system for evaluation of quality of undergraduate education in public health: a Delphi study based on CIPP evaluation model by Jiaqi PENG, Jiamin WANG, Gongming LI, Bingsong LI, Yanxiu LIU, Yujia FENG, Xiaojie SUN, Xuemei ZHEN

    Published 2024-11-01
    “…MethodsBased on the context, input, process, product (CIPP) evaluation model, a preliminary evaluation indicator system was constructed through literature review. Two rounds of Delphi expert consultation were conducted with 15 experts in social medicine and health services, epidemiology, biostatistics, microbial testing, health toxicology and nutrition, and educational management. …”
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  7. 21247

    Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

    Published 2025-03-01
    “…The results demonstrate that the BA-Kstar ensemble model achieved superior performance (R2 = 0.91, RMSE = 1.60, NSE = 0.91, and RSR = 0.30). Notably, manually constructed input scenarios outperformed automated feature selection methods, with maximum temperature emerging as the most significant predictor of Ep variability. …”
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  8. 21248

    Ferroptosis genes and ST-segment elevation myocardial infarction outcomes: A predictive signature by Xing-jie Wang, Lei Huang, Min Hou, Jie Guo, Xi-ming Li

    Published 2025-01-01
    “…Objective: The aim of this paper is to discover differentially expressed genes related to ferroptosis (DEFRGs) in patients with ST-segment elevation myocardial infarction (STEMI) and to construct a reliable prognostic signature that incorporates key DEFRGs and easily accessible clinical factors. …”
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  9. 21249

    Analysis of Underwater Topographic Survey of Stilling Basin Based on Unmanned Survey System by Hui Xie, Haoran Wang, Yayi Yang, Yongcan Chen, Jun Yang, Shuang Wang, Zhaowei Liu

    Published 2021-01-01
    “…In this paper, the combined technology was integrated with unmanned surface vehicle (USV) technology to construct an unmanned survey system suitable for underwater topographic survey in stilling basin, and it was applied to survey the underwater topography of the stilling basin of Tingzikou hydrojunction project. …”
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  10. 21250
  11. 21251

    Continuous and Discrete Similarity Coefficient for Identifying Essential Proteins Using Gene Expression Data by Jiancheng Zhong, Zuohang Qu, Ying Zhong, Chao Tang, Yi Pan

    Published 2023-06-01
    “…We also compared the PJC coefficient with other methods using the NF-PIN algorithm, which predicts proteins by constructing active PPI networks through dynamic gene expression. …”
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  12. 21252

    A Hierarchical Graph-Enhanced Transformer Network for Remote Sensing Scene Classification by Ziwei Li, Weiming Xu, Shiyu Yang, Juan Wang, Hua Su, Zhanchao Huang, Sheng Wu

    Published 2024-01-01
    “…Moreover, we develop a fine-grained graph neural network extractor that constructs the spatial topological relationships of pixel-level scene images, thereby aiding in the discrimination of similar complex scene categories. …”
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  13. 21253

    GIS-BASED ASSESSMENT OF GROUND WATER QUALITY FOR DRINKING PURPOSE BY WATER QUALITY INDEX APPROACHES IN BAHAWALPUR, PUNJAB by Ali Hassan, Haroon Rashid, Ahsan Sarfraz, Kashif Javed, Dawood Nawaz, Muhammad Faizan

    Published 2023-12-01
    “…The data collected and analyzed in this study could be used to design and construct a filtration plant facility to reduce water pollution in the area.…”
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  14. 21254

    How faculty with critical care specialties learn in a university hospital: a qualitative phenomenological study by Hyeyoon Jeong, Hyena Cho, Kyoung-Woo Seo, Janghoon Lee, Miran Kim, Jihye Yu

    Published 2025-01-01
    “…Objectives The study aims to explore the workplace learning experiences of medical faculty in critical care specialties at a university hospital, focusing on how they develop their professional identity and construct the meaning of their work.Design Qualitative, phenomenological study.Setting The current study was conducted at a university hospital in South Korea between November 2022 and October 2023.Participants Five faculty members (two males and three females) from critical care specialties (eg, emergency medicine) with over 15 years of experience, each having served as faculty at a university hospital for more than 5 years.Results Six key themes emerged: cultivating ‘doctor-ishness’ in the realm of critical care, beacon of inner drive: guiding professional growth, nexus for leveraging expertise and fostering professional growth, the challenging reality of becoming an ‘ideal’ faculty, the shifting tides of the medical profession’s role and weaving workplace learning into a unique rhythm of practice. …”
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  15. 21255

    MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level by Inyoung Sung, Sangseon Lee, Dongmin Bang, Dongmin Bang, Jungseob Yi, Sunho Lee, Sun Kim, Sun Kim, Sun Kim, Sun Kim

    Published 2025-01-01
    “…Given that a single mechanism involves multiple pathways, MDTR measures pathway-level perturbation by constructing a radial basis kernel-based toxicity space and measuring the Mahalanobis distance in the transcriptomic kernel space. …”
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  16. 21256

    How integrated knowledge translation worked to reduce federal policy barriers to the implementation of medication abortion in Canada: a realist evaluation by Sarah Munro, Kate Wahl, Sheila Dunn, Courtney Devane, Linda C. Li, Wendy V. Norman

    Published 2025-02-01
    “…Methods We conducted a realist evaluation of what iKT strategies worked, for whom, and in what context to impact federal mifepristone regulations. We constructed initial program theories (if–then statements about how iKT worked). …”
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  17. 21257

    Research on ultrasonic testing method for tangential contact stress based on equivalent medium theory by Nana Niu, Yongsheng Zhao, Zhifeng Liu, Ying Li, Lele Liu

    Published 2025-01-01
    “…An ultrasonic acoustic time difference model considering changes in contact surface material parameters is constructed based on the principle of acoustic elasticity of ultrasound. …”
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  18. 21258

    Tumour heterogeneity and personalized treatment screening based on single-cell transcriptomics by Xinying Zhang, Jiajie Xie, Zixin Yang, Carisa Kwok Wai Yu, Yaohua Hu, Jing Qin

    Published 2025-01-01
    “…Here, we collected five single-cell transcriptome datasets from patients with lung, breast, colorectal, gastric, and liver cancers and constructed multiple cancer blueprints of tumour cell heterogeneity. …”
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  19. 21259

    Wild Boar Attacks on Hunting Dogs in Czechia: The Length of the Hunting Season Matters by Jana Adámková, Karolína Lazárková, Jan Cukor, Hana Brinkeová, Jitka Bartošová, Luděk Bartoš, Kateřina Benediktová

    Published 2025-01-01
    “…Further investigation into wild boar and hunting dog interactions is necessary for constructing strategies to improve hunting practices and reduce dog injury risks.…”
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  20. 21260

    Two cellular models for analyzing mitochondrial heteroplasmy by Yaning Hu, Lin Jiang, Wen Liu, Xingbo Zhao

    Published 2025-01-01
    “…In this study, we developed two novel approaches to construct mitochondrial heteroplasmy cellular models. …”
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