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  1. 21121

    Association between internet use and depression among the middle-aged and elderly adults with multimorbidity in China: do gender differences exist? by Jiao Zhang, Jiao Zhang, Yuheng Jia, Lixin Hong, Yixin Zhang, Lihua Li, Kan Tian, Kan Tian

    Published 2025-01-01
    “…Logistic regression models were constructed to examine the effects of Internet use on depression, as well as comparing gender differences. …”
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  2. 21122

    Prediction of pulmonary embolism by an explainable machine learning approach in the real world by Qiao Zhou, Ruichen Huang, Xingyu Xiong, Zongan Liang, Wei Zhang

    Published 2025-01-01
    “…To address this, we employed an artificial intelligence–based machine learning algorithm (MLA) to construct a robust predictive model for PE. We retrospectively analyzed 1480 suspected PE patients hospitalized in West China Hospital of Sichuan University between May 2015 and April 2020. 126 features were screened and diverse MLAs were utilized to craft predictive models for PE. …”
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  3. 21123

    Biochemical and technological properties of moose (<i>Alces alces</i>) recombinant chymosin by D. V. Balabova, A. P. Rudometov, S. V. Belenkaya, A. N. Belov, A. D. Koval, A. A. Bondar, A. Yu. Bakulina, E. A. Rukhlova, V. V. Elchaninov, D. N. Shcherbakov

    Published 2022-06-01
    “…Within this study, we for the first time constructed an expression vector allowing production of a recombinant analog of moose chymosin in the expression system of Escherichia coli (strain SHuffle express). …”
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  4. 21124

    Study on the safety distance determination model for natural gas wells in Ordos Basin subsidence areas of coal mining by Wen Wang, Yang Zhang, Shuang Gong, Junqi Lei, Jiandong Ren, Yanxiong Ding, Xiaowei Lu

    Published 2025-01-01
    “…Abstract To optimize the safe distance between coal mining faces and natural gas wells, with the Ordos Basin as the engineering background for the intersectional development of natural gas and coal resources, a Gaussian function equation for subsidence curves under complete mining was proposed based on the probability integral method, and a model was constructed to determine the coordinated mining safety distance between coal mining faces and natural gas wells. …”
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  5. 21125

    Evaluation of Prediction Models for the Capping and Breaking Force of Tablets Using Machine Learning Tools in Wet Granulation Commercial-Scale Pharmaceutical Manufacturing by Sun Ho Kim, Su Hyeon Han, Dong-Wan Seo, Myung Joo Kang

    Published 2024-12-01
    “…<b>Conclusions</b>: These findings indicate that TBF, friability, and capping occurrence were successfully modeled using machine learning with a large dataset by constructing regression and classification models. Applying these models before tablet manufacturing can enhance product quality during wet granulation scale-up, particularly by preventing capping during the manufacturing process without damaging the tablets.…”
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  6. 21126

    Identification of a Seven-lncRNA-mRNA Signature for Recurrence and Prognostic Prediction in Relapsed Acute Lymphoblastic Leukemia Based on WGCNA and LASSO Analyses by Haiyan Qi, Long Chi, Xiaogang Wang, Xing Jin, Wensong Wang, Jianping Lan

    Published 2021-01-01
    “…Least absolute shrinkage and selection operator analysis showed that seven genes constructed a prognostic signature (including one lncRNA: LINC00652 and six mRNAs: INSL3, NIPAL2, REN, RIMS2, RPRM, and SNAP91). …”
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  7. 21127

    A Pool of Bacterium-like Particles Displaying African Swine Fever Virus Antigens Induces Both Humoral and Cellular Immune Responses in Pigs by Jingshan Huang, Hongxia Wu, Tianqi Gao, Huanjie Zhai, Assad Moon, Xin Song, Shuwen Li, Zhanhao Lu, Jing Lan, Dailang Zhong, Xinyu Zhang, Hua-Ji Qiu, Yongfeng Li, Yuan Sun

    Published 2024-12-01
    “…This underscores the urgent need for safe and effective ASF vaccines. Methods: Here, we constructed five bacterium-like particles (BLPs) that each display one of the five ASFV antigens (F317L, H171R, D117L, B602L, and p54) based on the Gram-positive enhancer matrix-protein anchor (GEM-PA) system. …”
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  8. 21128

    Fusobacterium nucleatum promotes colorectal cancer liver metastasis via miR-5692a/IL-8 axis by inducing epithelial-mesenchymal transition by Yulong Yu, Han Yin, Bili Wu, Weiheng Zhao, Yuan Wang, Aifeina Aili, Mu Yang, Qianqian Yu, Xianglin Yuan

    Published 2025-01-01
    “…The mouse model of CRC liver metastasis was constructed by spleen injection, and the degree of liver metastasis was assessed by in vivo bioluminescence imaging. …”
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  9. 21129

    Development and validation of a novel AI-derived index for predicting COPD medical costs in clinical practice by Guan-Heng Liu, Chin-Ling Li, Chih-Yuan Yang, Shih-Feng Liu

    Published 2025-01-01
    “…A Gradient Boosting model was constructed, optimized with Recursive Feature Elimination (RFE), and evaluated using 5-fold cross-validation on an 80/20 train-test split. …”
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  10. 21130

    A Novel Metabolic Connectome Method to Predict Progression to Mild Cognitive Impairment by Min Wang, Zhuangzhi Yan, Shu-yun Xiao, Chuantao Zuo, Jiehui Jiang

    Published 2020-01-01
    “…Individual metabolic network based on connectome analysis was constructed, and the metabolic connectivity in this network was extracted as predictive features. …”
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  11. 21131

    Estimating Seafloor Topography of the South China Sea Using SWOT Wide-Swath Altimetry Data by Fengshun Zhu, Jinbo Li, Yang Li, Jianqiao Xu, Jinyun Guo, Jiangcun Zhou, Heping Sun

    Published 2025-01-01
    “…This study utilized 15 cycles of SWOT Level-3 product to construct seafloor topography model of the South China Sea by linear regression analysis. …”
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  12. 21132

    Contrast-Enhanced CT Texture Analysis for Distinguishing Fat-Poor Renal Angiomyolipoma From Chromophobe Renal Cell Carcinoma by Guangjie Yang MD, Aidi Gong BS, Pei Nie MD, Lei Yan BS, Wenjie Miao BS, Yujun Zhao BS, Jie Wu MD, Jingjing Cui BS, Yan Jia BS, Zhenguang Wang MD

    Published 2019-10-01
    “…The 2D and 3D CTTA models were constructed with the least absolute shrinkage and selection operator algorithm and texture scores were calculated. …”
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  13. 21133

    STLNet: Symmetric Transformer Learning Network for Remote Sensing Image Change Detection by Liye Mei, Andong Huang, Zhaoyi Ye, Yaxiaer Yalikun, Ying Wang, Chuan Xu, Wei Yang, Xinghua Li

    Published 2025-01-01
    “…To address this, we propose a symmetric transformer learning network (STLNet) specifically tailored for remote sensing image CD tasks, constructed entirely using transformers. The STLNet is designed to leverage the intrinsic capability of transformers to model extensive long-range dependencies effectively. …”
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  14. 21134

    A single-surgeon experience with the internal joint stabilizer of the elbow across 56 cases by John J. Heifner, MD, Gagan Grewal, MD, Christopher J. Castagno, MD, Gil Gontre, MD

    Published 2025-01-01
    “…Adjuvant stabilization—whether internal or external—is intended to acutely stabilize the elbow and off-load the repair construct(s) during early mobilization. Our objective was to report clinical outcomes for a single-surgeon consecutive series using the internal joint stabilizer (IJS) of the elbow. …”
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  15. 21135

    Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors by Yunbi Liu, Wei Yang, Guangnan She, Liming Zhong, Zhaoqiang Yun, Yang Chen, Ni Zhang, Liwei Hao, Zhentai Lu, Qianjin Feng, Wufan Chen

    Published 2019-01-01
    “…Then, nonparametric priors of soft tissue and bone components are constructed by sampling image patches from the selected soft tissue and bone images according to the corresponding fields. …”
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  16. 21136

    Creep model of bond-degradation in deep granite based on variable radius particle clump by Chunzhe Jin, Chuang Sun, Yunhe Ao, Dong Xue, Xin Lu, Qing Zhang

    Published 2025-01-01
    “…The mechanical properties and creep characteristics of deep granite were obtained by indoor tests, and a variable radius particle clump model was constructed based on the particle flow method. The bond-weakening-friction-strengthening model was combined with the parallel bond stress corrosion method to establish the bond-degradation creep model of granite. …”
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  17. 21137

    EMD-GM-ARMA Model for Mining Safety Production Situation Prediction by Menglong Wu, Yicheng Ye, Nanyan Hu, Qihu Wang, Huimin Jiang, Wen Li

    Published 2020-01-01
    “…Finally, aiming to predict the mining safety production situation, the EMD-GM-ARMA model was constructed via superimposing the prediction results of each subsequence, thereby compared to the ARIMA model, wavelet neural network model, and PSO-SVM model. …”
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  18. 21138

    Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease by Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao, Lijuan Wang

    Published 2025-02-01
    “…Edaravone dexborneol (EDB) is known to target multiple pathways involved in fibrosis. Methods We constructed the CCH mouse models that were subjected to either PBS or EDB at different concentrations. …”
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  19. 21139

    An expert perspective on diversity-oriented standards for assessing sex and gender in clinical research by Hannah R. Hambruch, Nora M. Laskowski, Robert-Paul Juster, Georg Halbeisen, Georgios Paslakis

    Published 2025-01-01
    “…Inclusive research must consider the diversity of sex and gender to eliminate inequalities and improve health outcomes.MethodsA two-stage expert survey was conducted using a self-developed questionnaire in which the constructs of sex, gender, and gender expression were considered. …”
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  20. 21140

    Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California by Yen-Yi Juo, Melinda A. Maggard Gibbons, Erik Dutson, Anne Y. Lin, Jane Yanagawa, O. Joe Hines, Guido Eibl, Yijun Chen

    Published 2018-01-01
    “…Regression models were constructed to adjust for other carcinogenic factors. …”
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