Machine learning based predictive model and genetic mutation landscape for high-grade colorectal neuroendocrine carcinoma: a SEER database analysis with external validation by Ruixin Wu, Ruixin Wu, Sihao Chen, Sihao Chen, Yi He, Yi He, Ya Li, Song Mu, Aishun Jin, Aishun Jin

“…This study was designed to construct a risk model based on comprehensive clinical and mutational genomics data to facilitate clinical decision making.MethodsA retrospective analysis was conducted using data from the Surveillance, Epidemiology, and End Results (SEER) database, spanning 2000 to 2019. …”
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Quantitative evaluation of two-way referral policies based on PMC index model by Jing Gong, Leiyu Shi, Jinsong Deng, Wanzhen Xie, Shengwu Liao, Oudong Xia, Gang Sun

“…Basing on the focus of the two-way referral policy identified by text-mining methods, we constructed a PMC index model containing 9 primary and 43 secondary variables to conduct a quantitative evaluation of the two-way referral policy. …”
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Analysis of the mediating role of life style in the relationship between health literacy and self-rated health employing structural equation modeling by Mansour Bagherinia, Shahab Rezaeian, Ebrahim Shakiba, Raheleh Maleki, Abbas Mohammad Karimi Mazhin, Hadi Darvishigilan, Maryam Janatolmakan, Badriyeh Karami

“…In addition, the principal hypothesis of this research posits the mediating function of lifestyle within the interrelationship between the two constructs of health literacy and self-rated health. …”
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An Aptamer Sensor Based on Alendronic Acid-Modified Upconversion Nanoparticles Combined with Magnetic Separation for Rapid and Sensitive Detection of Thiamethoxam by Qian Huang, Lu Han, Hui Ma, Weijie Lan, Kang Tu, Jing Peng, Jing Su, Leiqing Pan

“…Herein, we introduced an innovative fluorescence biosensor constructed from alendronic acid (ADA)-modified upconversion nanoparticles (UCNPs) linked with magnetic nanoparticles (MNPs) via aptamer recognition for the detection of thiamethoxam. …”
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Water-Soluble Polymer Assists N-Methyl-D-Aspartic Acid Receptor 2B siRNA Delivery to Relieve Chronic Inflammatory Pain In Vitro and In Vivo by Jie Peng, Jiahui Ma, Xue Yang, Huan He, Haopeng Wu, Tongtong Ma, Jianhua Lu

“…We constructed a water-soluble lipopolymer (WSLP) as a nonviral gene carrier to deliver siRNA targeting NR2B. …”
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Calibration of double electroinduction spherical electric field strength sensor in a homogeneous field by S. V. Biryukov, L. V. Tyukina, A. V. Tyukin

“…For measuring the strength of electric fields near highvoltage equipment, dual electroinduction spherical sensors, which are a constructive combination of two double sensors into one, are promising. …”
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Three-Dimensional Numerical Modeling and Roof Deformation Analysis of Yuanjue Cave Based on Point Cloud Data by Zhigang Meng, Manchao He, Zhigang Tao, Bin Li, Gang Zhao, Mingru Xiao

“…Then, based on FLAC3D finite difference numerical simulation technology, an accurate three-dimensional numerical calculation model of Yuanjue Cave was constructed. Finally, the model was used to analyze the roof stability of Yuanjue Cavern, revealing the deformation laws of the Yuanjue Cave roof under static load conditions, and the numerical calculation results were compared with the on-site measured results, verifying the feasibility of the high-precision modeling method, and the reliability of the numerical calculation results provided a reference for the preventive protection of the cultural relics of the cave temple.…”
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Low-carbon economic dispatch of integrated energy system with carbon capture power plant and multiple utilization of hydrogen energy by Jiarui Wang, Xiu Ji, Xiangdong Meng, Yang Bai, Meiyue Li

“…It can utilize the potential of collaborative operation with carbon capture power plants; on this basis, consider the transferability and substitutability characteristics of electric heating gas load, and construct an electric heating gas comprehensive demand response model; secondly, consider the mutual recognition relationship between carbon quotas and green certificates, Propose a green certificate-carbon trading mechanism; finally establish an integrated energy system with the optimization goal of minimizing the sum of energy purchase cost, demand response compensation cost, wind curtailment cost, carbon storage cost, carbon purchase cost, carbon trading cost and green certificate trading compensation. …”
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A new score for predicting intracranial hemorrhage in patients using anticoagulant drugs by Fuxin Ma, Zhiwei Zeng, Jiana Chen, Chengfu Guan, Wenlin Xu, Chunhua Wang, Jinhua Zhang

“…Multifactorial analysis showed that male, leukoaraiosis, high risk of falls, APTT ≥ 45.4 s, and FIB ≥ 4.2 g/L were independent risk factors for cerebral hemorrhage, and β-blockers were protective factors. The model was constructed using these six factors with an AUC value of 0.883. …”
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Fatigue crack behaviour: comparing three-point bend test and wedge splitting test data on vibrated concrete using Paris' law by S. Seitl, T. Thienpont, W. De Corte

“…The fatigue behaviour of concrete has become more important for the design of constructions due to the desire to build slimmer structures, which are more sensitive to fatigue loading. …”
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Cooperative game scheduling and revenue sharing strategy for virtual power plants considering scenery uncertainty by SONG Duoyang, XUE Tianliang, LI Yipu, TU Jintong, BI Yuhao, WANG Mankang

“…Secondly, the same type of distributed energy sources form alliances and aim to maximize the revenue from power sales, and construct a cooperative game scheduling model for multiple alliances of virtual power plants. …”
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Characterization of stem cell landscape and identification of stemness-relevant prognostic gene signature to aid immunotherapy in breast cancer by Xiaozhou Yang, Xiaojun Yang, Haili Tang, Xin Chen, Jiangang Wang, Huadong Zhao

“…A 5-gene stemness model was constructed, showing that higher stemness scores correlated with poorer prognosis. …”
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Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry by Johanna C.W. Deenen, André L.M. Verbeek, Pieter A. van Doorn, Catharina G. Faber, Anneke J. van der Kooi, Nicolette C. Notermans, Jan J.G.M. Verschuuren, Baziel G.M. van Engelen, Nicol C. Voermans

“…Nationwide incidence maps were constructed for myotonic dystrophy, progressive (spinal) muscular atrophy, chronic inflammatory demyelinating polyneuropathy, facioscapulohumeral muscular dystrophy, inclusion body myositis, hereditary motor and sensory neuropathy, Pompe disease and oculopharyngeal muscular dystrophy. …”
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Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology by Qi Wu, Chen Sun, Liping Guo, Yujia Xie, Jinpeng Zhang, Jinpeng Zhang, Dehui Yin, Dehui Yin

“…Recombinant T4SS proteins were prepared, and an indirect ELISA method was established for serological diagnosis of human brucellosis.ResultsSeven T4SS proteins (rVirB3, rVirB4, rVirB9, rBMEII0036, rVirB8, rVirB11, and rVirB10) were expressed used to construct the indirect ELISA method which showed high diagnostic accuracy. …”
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Factors Associated with PMTCT Cascade Completion in Four African Countries by Jodie Dionne-Odom, Thomas K. Welty, Andrew O. Westfall, Benjamin H. Chi, Didier Koumavi Ekouevi, Margaret Kasaro, Pius M. Tih, Alan T. N. Tita

“…Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis. …”
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Deep Learning Applications in Ionospheric Modeling: Progress, Challenges, and Opportunities by Renzhong Zhang, Haorui Li, Yunxiao Shen, Jiayi Yang, Wang Li, Dongsheng Zhao, Andong Hu

“…Additionally, this study explores the potential of deep learning in ionospheric modeling for the early warning of geological hazards such as earthquakes, volcanic eruptions, and tsunamis, offering new insights for constructing ionospheric-geological activity warning models. …”
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Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer? by Jia-Le Zhang, Zhen-Ning Wang, Hui-Mian Xu, Zhi Zhu, Bao-Jun Huang

“…Univariate and multivariate analyses of preoperative examination results were performed to identify the predictors of metastatic scope. ROC curves were constructed, and the area under the curve (AUC) was calculated to estimate diagnostic values. …”
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DEPEND study protocol: early detection of patients with pancreatic cancer – a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as scr... by Christopher D Byrne, Sam Wilding, Paul Remi Afolabi, Declan McDonnell, Victoria Goss, Jocelyn Walters, Zaed Z Hamady

“…In this study, we propose the use of a diagnostic algorithm that combines tests of pancreatic exocrine function (faecal elastase-1 (FE-1) test and the 13C-mixed triglyceride (13C-MTG) breath test) to identify patients with PC that urgently needs imaging studies.Methods and analysis This prospective pilot (proof of concept) study will be carried out on 25 patients with resectable PC, 10 patients with chronic pancreatitis and 25 healthy volunteers. This study will construct a predictive algorithm for PC, using two tests of pancreatic exocrine function, FE-1 test and the 13C-MTG breath test. …”
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Psychometric Properties of the Abdominal Pain Index (API) in the Iranian Adolescent Population by Sepideh Hoseini, Mahdi Jafari, Zahra Asl Soleimani, Kaveh Qaderi Bagajan, Meysam Sadeghi, Shadi Zolfaghari

“…Also, to evaluate the construct validity of API, exploratory and confirmatory factor analysis methods were applied. …”
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Investigation of Theoretical Models, Pumping-Recharge Well Arrangements and System Performance of Abandoned Mine Water Source Heat Pump by Zhiqiang Zhang, Wenchao Zu, Wenke Zhang, Kexun Wang, Xueqing Ma, Ping Cui

“…Finally, by choosing a residential building as the analysis object, a simulation model of the abandoned mine water source heat pump heating system is constructed, which is compared with a gas boiler heating system, revealing the energy savings and environmental protection benefits of the abandoned mine water source heat pump system. …”
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