Targeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines by Sanchari Paul, Mustafa Kaya, Olivia Johnsson, Hanna Grauers Wiktorin, Andreas Törnell, Mohammad Arabpour, Kristoffer Hellstrand, Anna Martner

“…When comparing antigens admixed with CTA1-DD to those fused with a CTA1-based adjuvant, the fusion construct elicited the strongest immunogenicity. Nevertheless, by administrating a 20-fold higher antigen dose also the admix formulation provided efficient protection against metastasis.…”
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Development of Prevascularized Synthetic Block Graft for Maxillofacial Reconstruction by Borvornwut Buranawat, Abeer Shaalan, Devy F. Garna, Lucy Di Silvio

“…This innovative strategy can potentially enhance vascularization in large tissue-engineered constructs, addressing a critical limitation in current bone regeneration techniques. …”
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A bi-subpopulation coevolutionary immune algorithm for multi-objective combinatorial optimization in multi-UAV task allocation by Xi Chen, Yu Wan, Jingtao Qi, Zipeng Zhao, Yirun Ruan, Jun Tang

“…Therefore, this paper constructs a Multi-objective Combinatorial Optimization in Multi-UAV Task Allocation Problem (MCOTAP) model, and proposes a Bi-subpopulation Coevolutionary Immune Algorithm (BCIA). …”
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Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation by Shuxiao Chen, Xiaotian Liu, Xincheng Zhou, Weixiao Lin, Minting Liu, Haoran Ma, Keli Zhong, Qiming Ma, Chengjian Qin, Chengjian Qin

“…The purpose of this study is to investigate the role of ATL-I in the progression of AAA.MethodsAAA was constructed in C57BL/6 mice by porcine pancreatic elastase (PPE)-incubation, and the diameter of the aorta was measured by ultrasound. …”
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Matrix Metalloproteinase‐Responsive Controlled Release of Self‐Assembly Nanoparticles Accelerates Heart Valve Regeneration In Situ by Orchestrating Immunomodulation by Xing Chen, Yunlong Wu, Peng Song, Liandong Feng, Ying Zhou, Jiawei Shi, Nianguo Dong, Weihua Qiao

“…In vivo, this valve scaffold promises to mitigate early inflammatory damage and provide a pro‐endothelialization niche for scaffolds' constructive remodeling. With the use of cell coculture systems and transcriptome sequencing, the mechanism of immune‐modulating scaffold accelerating endothelialization is being elucidated. …”
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Association of dietary niacin intake with osteoporosis in the postmenopausal women in the US: NHANES 2007–2018 by Li Li, Wankun Liang, Bing Deng, Yue Jiang, Xiaomin Huang, Yanlin Zhang, Tianrui Lu, Lu Wang, Yunxiang Xu, Guizhen Chen

“…Multivariate logistic regression models were constructed to determine the association between dietary niacin intake and the incidence of osteoporosis. …”
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The highly pathogenic strain of porcine deltacoronavirus disrupts the intestinal barrier and causes diarrhea in newborn piglets by Xin Yao, Wei-Hong Lu, Wen-Ting Qiao, Yu-Qian Zhang, Bao-Ying Zhang, Hui-Xin Li, Jin-Long Li

“…Five amino acid mutations are seen for the first time in the S protein. By constructing 3D models, it was found that the S1-NTD/CTD and S2-HR-C regions produced structural alterations. …”
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Analysis of tensile properties in tempered martensite steels with different cementite particle size distributions by Kengo Sawai, Keiya Sugiura, Toshio Ogawa, Ta-Te Chen, Fei Sun, Yoshitaka Adachi

“…Using the results obtained by the experimental approach, an image-based regression model was constructed that can accurately suggest the relationship between the microstructure and tensile properties of tempered martensite steel. …”
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Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics by You Hu, Jun Xu, Jian Lv, Yan Qin, Yongda Lu, Fan Cen, Hongbao Yang, Kai Chen, Suhua Xia

“…Patients in the high-risk subgroup exhibited increased expression of pro-tumor genes and reduced immune infiltration, correlating with poorer survival. We further constructed a robust risk scoring model incorporating these genes, achieving AUC values of 0.72, 0.69, and 0.66 for predicting 1-, 3-, and 5-year survival in the TCGA dataset. …”
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Specific Immune Responses and Oncolytic Effects Induced by EBV LMP2A-Armed Modified Ankara-Vaccinia Virus Vectored Vaccines in Nasopharyngeal Cancer by Liying Sun, Chao Liu, Junping Peng

“…Methods: The modified vaccinia virus Ankara (MVA) is universally used in vector vaccine research because of its excellent safety profile and highly efficient recombinant gene expression. Here, we constructed a novel MVA-LMP2A recombinant virus and investigated its specific immune response induction and oncolytic effect. …”
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A Multi-Time Scale Scheduling Model for Power Generation Systems with a High Proportion of New Energy Including Pumped Storage Power Stations by GU Huijie, ZHOU Huafeng, PENG Chaoyi, HU Yaping, ZHAO Xinyi, XIE Jun, SHI Xionghua

“…Based on the characteristics that the prediction accuracy of wind, photovoltaic (PV) and load power improves step by step with the shortening of time scales, a three-phase coordinated scheduling model is constructed with the goal of minimizing the total operating cost of the system, which includes a 24-hour day-ahead plan, a 1-hour intraday plan and a 15-minute real-time plan. …”
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Magnesium and silicon recovery from chrysotile asbestos waste of the deposit Zhitikara, Kazakhstan by R. A. Shayakhmetova, A. A. Mukhametzhanova, D. N. Akbayeva, A. Zh. Terlikbaeva, P. A. Osipov, A. M. Alimzhanova, A. A. Zharmenov

“…Batch reactors are used in both laboratory and pilot experiments, and initial trials are conducted in a recently constructed industrial Ti reactor at the Kostanay Minerals JSC plant in the Kostanay region of Zhitikara. …”
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Mediating effect of social support between depressive symptoms and sarcopenia in the elderly by Jia Mei, Xiuna Sun, Dianju Qin, Jing Xu, Mengze Xu, Li Duan, Lanfang Jia

“…[Methods] A total of 1 040 elderly people were investigated with the general information questionnaire, geriatric depression scale-5, social support rating scale and strength, assistance with walking, rise from a chair, climb stairs and falls.Pearson correlation analysis was used to analyze the relationship between depressive symptoms, social support and sarcopenia.Multiple stepwise regression analysis and AMOS26.0 were used to construct a structural equation model and verify the mediating effect of social support between depressive symptoms and sarcopenia. …”
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Enhancing Thermal Comfort in Historic Buildings by Wind-Driven Ventilation Systems—A Case Study of the Praterateliers in Vienna by Aida Shayegani, Viera Joklova, Katarina Kristianova, Juraj Illes

“…This research not only advances the application of passive cooling strategies in heritage buildings but also provides scalable solutions for addressing urban overheating in modern constructions.…”
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Discrete Element Simulation Analysis of the Bending and Toppling Failure Mechanisms of High Rock Slopes by Zhigang Meng, Yongli Hou, Longji Guo, Fengnian Wang, Kuiming Liu, Gan Qi, Juan Ma

“…Based on the discrete element method, the geological model of layered excavation of the thin layer slope can be constructed. Combined with indoor and outdoor assessments, the characteristics of toppling deformation of the thin layer open-air slope can be studied and summarized. …”
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An improved fuzzy time series forecasting model based on hesitant fuzzy sets by Lubna Shafi, Shilpi Jain, Praveen Agarwal, Pervaiz Iqbal, Aadil Rashid Sheergojri

“…The proposed method utilizes trapezoidal and bell-shaped fuzzy membership functions for constructing HFSs. Ahesitant fuzzy weighted averaging operator is then applied to the Hesitant Fuzzy Elements (HEFs) to create fuzzy logical relations. …”
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Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance by Zachary E. Markow, Jason W. Trobaugh, Edward J. Richter, Kalyan Tripathy, Sean M. Rafferty, Alexandra M. Svoboda, Mariel L. Schroeder, Tracy M. Burns-Yocum, Karla M. Bergonzi, Mark A. Chevillet, Emily M. Mugler, Adam T. Eggebrecht, Joseph P. Culver

“…Herein, simulations indicated reducing inter-optode spacing to 6.5 mm, creating a higher-density grid with more source-detector distances, would further improve image quality and noise-resolution tradeoff, with diminishing returns below 6.5 mm. We then constructed an ultra-high-density DOT system (6.5-mm spacing) with 140 dB dynamic range that imaged stimulus-evoked activations with 30–50% higher spatial resolution and repeatable multi-focal activity with excellent agreement with participant-matched fMRI. …”
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Distributed optimization and scheduling strategy for source load storage distribution grid based on alliance chain by Jinhua Tian, Yueyuan Zhang, Yanan Gao, Yu Qin, Bihan Fan, Cheng Zhang, Qiqi Zang

“…In response to issues as difficult global information acquisition, less consideration of flexible load and energy storage unit access, individual deception, and insufficient security in the optimization scheduling process of active distribution networks, this paper constructed a distribution network optimization scheduling model that includes sources, loads, and storage. …”
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Digital mental health treatment implementation playbook: successful practices from implementation experiences in American healthcare organizations by David C. Mohr, David C. Mohr, Alexandra L. Silverman, Alexandra L. Silverman, Soo Jeong Youn, Soo Jeong Youn, Soo Jeong Youn, Patricia Areán, Andrew Bertagnolli, Jenna Carl, Tarolyn Carlton, Neha Chaudhary, David Cooper, Shelly DeVito, Stephanie Eaneff, Megan Flom, Valerie L. Forman-Hoffman, Leanna Fortunato, Karen Franchino, Andrea K. Graham, Heidi Greenberger, Jessica Hauflaire, Benjamin Kaveladze, Rachel Kornfield, Kaylee P. Kruzan, Eric Kuhn, Eric Kuhn, Carolyn MacIver, Frederick Muench, Regina Misch, Adrian Ortega, Lisa Palko, Derek Richards, Derek Richards, Louisa Salhi, Jonathan Schremp, Eva Szigethy, Eva Szigethy, Nathan Tatro, Bethany A. Teachman, Bethany A. Teachman, Trina Histon

“…Concepts and thematic constructs were extracted by experts in qualitative data analysis. …”
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Understanding the misophonic experience: a mixed method study by Yesim Ozuer, Rilana Cima, Rilana Cima, Rilana Cima, Elke Kestens, Ilse Van Diest

“…Also, four emotional reaction themes were constructed: “anger/defensive rage,” “disgust,” “fear,” and “safety behaviors.” …”
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